المؤلفون: Larson EA; Charles River Laboratories, Laval, Quebec, Canada., Accardi MV; Charles River Laboratories, Laval, Quebec, Canada., Zhong Y; Charles River Laboratories, Laval, Quebec, Canada., Paquette D; Charles River Laboratories, Laval, Quebec, Canada., Authier S; Charles River Laboratories, Laval, Quebec, Canada.; Faculté de Médecine Vétérinaire, Université de Montréal, St-Hyacinthe, Quebec, Canada.

المصدر: International journal of toxicology [Int J Toxicol] 2021 Oct; Vol. 40 (5), pp. 403-412.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Seizures/*chemically induced, Animals ; Cell Death ; Drug Development ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Ion Channels/physiology ; Neurons/pathology ; Neurons/physiology ; Seizures/pathology ; Seizures/physiopathology ; Synaptic Transmission

المؤلفون: Trefry JC; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Rossi FD; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Accardi MV; Charles River (formerly Citoxlab North America), Laval, Canada., Dorsey BL; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Sprague TR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Wollen-Roberts SE; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Shamblin JD; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Kimmel AE; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Glass PJ; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Miller LJ; Veterinary Medicine Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Burke CW; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Cardile AP; Division of Medicine, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Smith DR; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Bavari S; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Authier S; Charles River (formerly Citoxlab North America), Laval, Canada., Pratt WD; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Pitt ML; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America., Nasar F; Virology Division, United States Army Medical Research Institute of Infectious Diseases, Frederick, Maryland, United States of America.

المصدر: PLoS neglected tropical diseases [PLoS Negl Trop Dis] 2021 Jun 17; Vol. 15 (6), pp. e0009424. Date of Electronic Publication: 2021 Jun 17 (Print Publication: 2021).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101291488 Publication Model: eCollection Cited Medium: Internet ISSN: 1935-2735 (Electronic) Linking ISSN: 19352727 NLM ISO Abbreviation: PLoS Negl Trop Dis Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal* , Electroencephalography* , Encephalitis Virus, Eastern Equine*, Alphavirus Infections/*virology , Monitoring, Physiologic/*instrumentation , Telemetry/*instrumentation, Aerosols ; Alphavirus Infections/pathology ; Animals ; Blood Pressure ; Body Temperature ; Chlorocebus aethiops ; Female ; Heart Rate ; Humans ; Macaca fascicularis ; Male ; Monitoring, Physiologic/methods ; Motor Activity ; Respiratory Physiological Phenomena ; Telemetry/methods ; Vero Cells

المؤلفون: Boulay E; Charles River Laboratories, Laval, Quebec, Canada.; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Troncy E; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Accardi MV; Charles River Laboratories, Laval, Quebec, Canada., Pugsley MK; Toxicology, Cytokinetics, South San Francisco, CA, USA., Downey AM; Charles River Laboratories, Laval, Quebec, Canada., Miraucourt L; Charles River Laboratories, Laval, Quebec, Canada., Huang H; Charles River Laboratories, Laval, Quebec, Canada., Menard A; Charles River Laboratories, Laval, Quebec, Canada., Tan W; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Dubuc-Mageau M; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Sanfacon A; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Guerrier M; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada., Authier S; Charles River Laboratories, Laval, Quebec, Canada.; 70354Faculté de médecine vétérinaire, Université de Montréal, Québec, Canada.

المصدر: International journal of toxicology [Int J Toxicol] 2020 Nov/Dec; Vol. 39 (6), pp. 530-541. Date of Electronic Publication: 2020 Oct 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Sage Publications Country of Publication: United States NLM ID: 9708436 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1092-874X (Electronic) Linking ISSN: 10915818 NLM ISO Abbreviation: Int J Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Arrhythmias, Cardiac/*etiology , Epinephrine/*pharmacology , Phenethylamines/*pharmacology , Ranolazine/*pharmacology , Sulfonamides/*pharmacology , Verapamil/*pharmacology, Animals ; Anti-Arrhythmia Agents/administration & dosage ; Anti-Arrhythmia Agents/pharmacology ; Arrhythmias, Cardiac/prevention & control ; Biomarkers ; Body Temperature ; Dogs ; Dose-Response Relationship, Drug ; Electrocardiography ; Female ; Heart Rate ; Male ; Phenethylamines/administration & dosage ; Ranolazine/administration & dosage ; Stress, Physiological/drug effects ; Sulfonamides/administration & dosage ; Verapamil/administration & dosage

المؤلفون: Miraucourt LS; Charles River Laboratories Laval, 445 Armand-Frappier Blvd., Laval, QC H7V 4B3, Canada., Accardi MV; Charles River Laboratories Laval, 445 Armand-Frappier Blvd., Laval, QC H7V 4B3, Canada., Asin KE; Millennium Pharmaceuticals, Inc. (Takeda Pharmaceuticals International Co.), 35 Lansdowne Street, Cambridge, MA 02139, United States., Pugsley MK; Charles River Laboratories Laval, 445 Armand-Frappier Blvd., Laval, QC H7V 4B3, Canada., Curtis MJ; Cardiovascular Division, Faculty of Life Sciences & Medicine, King's College London, Rayne Institute, St Thomas' Hospital, London SE17EH, United Kingdom., Authier S; Charles River Laboratories Laval, 445 Armand-Frappier Blvd., Laval, QC H7V 4B3, Canada. Electronic address: simon.authier@crl.com.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2020 Sep; Vol. 105, pp. 106883. Date of Electronic Publication: 2020 May 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

مواضيع طبية MeSH: Central Nervous System/*metabolism , Central Nervous System/*physiology , Neurons/*metabolism , Neurons/*physiology , Primates/*metabolism , Primates/*physiology, Animals ; Cells, Cultured ; Electrophysiology/methods ; Female ; Male ; Patch-Clamp Techniques/methods ; Rats ; Receptors, AMPA

المؤلفون: Delaunois A; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium. Electronic address: annie.delaunois@ucb.com., Accardi MV; Citoxlab, a Charles River company, 445 boulevard Armand Frappier, Laval, QC, Canada., André V; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Authier S; Citoxlab, a Charles River company, 445 boulevard Armand Frappier, Laval, QC, Canada., Bouzom F; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Hebeisen S; B'SYS GmbH, Benkenstrasse 254, Witterswil, Switzerland., Lamberty Y; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Laredj F; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Leclercq K; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Letombe AG; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Rosseels ML; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Rospo CC; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Tordeur MC; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Valentin JP; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium., Wood M; UCB Biopharma SRL, chemin du Foriest, Braine-l'Alleud, Belgium.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2020 Jul - Aug; Vol. 104, pp. 106874. Date of Electronic Publication: 2020 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

مواضيع طبية MeSH: Ion Channels/*drug effects , Risk Assessment/*methods , Seizures/*chemically induced, Animals ; CHO Cells ; Cricetulus ; Dogs ; Electroencephalography ; Electrophysiological Phenomena ; Female ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Ion Channels/metabolism ; Lead ; Male ; Mice ; Patch-Clamp Techniques ; Rats ; Seizures/physiopathology ; Telemetry

المؤلفون: Larson EA; Integrated Program in Neuroscience, McGill University, Montréal, Québec, Canada H3A 2B4.; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 0B1, Québec, Canada., Accardi MV; Graduate Program in Pharmacology, McGill University, Montréal, Québec, Canada H3G 1Y6.; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 0B1, Québec, Canada., Wang Y; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0J9.; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada R3E 3J7.; The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba Canada R3E 3P4., D'Antoni M; Integrated Program in Neuroscience, McGill University, Montréal, Québec, Canada H3A 2B4.; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 0B1, Québec, Canada., Karimi B; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0J9.; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada R3E 3J7.; The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba Canada R3E 3P4., Siddiqui TJ; Department of Physiology and Pathophysiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada R3E 0J9.; Neuroscience Research Program, Kleysen Institute for Advanced Medicine, Health Sciences Centre, Winnipeg, Manitoba, Canada R3E 3J7.; The Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba Canada R3E 3P4., Bowie D; Department of Pharmacology and Therapeutics, McGill University, Montréal H3G 0B1, Québec, Canada derek.bowie@mcgill.ca.

المصدر: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2020 Apr 22; Vol. 40 (17), pp. 3348-3359. Date of Electronic Publication: 2020 Mar 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis Regulatory Proteins/*metabolism , Cerebellum/*metabolism , Interneurons/*metabolism , Microtubule-Associated Proteins/*metabolism , Nitric Oxide/*metabolism , Signal Transduction/*physiology, Animals ; Cerebellum/drug effects ; Enzyme Inhibitors/pharmacology ; Excitatory Amino Acid Antagonists/pharmacology ; Female ; Interneurons/drug effects ; Male ; Mice ; Neural Inhibition/drug effects ; Neural Inhibition/physiology ; Nitric Oxide Synthase Type I/antagonists & inhibitors ; Patch-Clamp Techniques ; Signal Transduction/drug effects ; Synaptic Transmission/drug effects ; Synaptic Transmission/physiology

المؤلفون: Accardi MV; CiToxLAB North America, Laval, QC, Canada., Donini O; Soligenix, Inc., Princeton, NJ, USA., Rumage A; Soligenix, Inc., Princeton, NJ, USA., Ascah A; CiToxLAB North America, Laval, QC, Canada., Haruna J; CiToxLAB North America, Laval, QC, Canada., Pouliot M; CiToxLAB North America, Laval, QC, Canada., Bujold K; CiToxLAB North America, Laval, QC, Canada., Huang H; CiToxLAB North America, Laval, QC, Canada., Wierzbicki W; CiToxLAB North America, Laval, QC, Canada., Stamatopoulos J; CiToxLAB North America, Laval, QC, Canada., Naraghi H; CiToxLAB North America, Laval, QC, Canada., Measey T; Soligenix, Inc., Princeton, NJ, USA., Authier S; CiToxLAB North America, Laval, QC, Canada.; Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, QC, Canada.

المصدر: International journal of radiation biology [Int J Radiat Biol] 2020 Jan; Vol. 96 (1), pp. 100-111. Date of Electronic Publication: 2018 Apr 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 8809243 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1362-3095 (Electronic) Linking ISSN: 09553002 NLM ISO Abbreviation: Int J Radiat Biol Subsets: MEDLINE

مواضيع طبية MeSH: Mouth/*radiation effects , Radiation Protection/*methods, Acute Radiation Syndrome/blood ; Acute Radiation Syndrome/etiology ; Acute Radiation Syndrome/pathology ; Animals ; Citrulline/blood ; Cobalt Radioisotopes/adverse effects ; Gamma Rays/adverse effects ; Macaca mulatta ; Male ; Survival Analysis ; Ulcer/blood ; Ulcer/etiology ; Ulcer/pathology

المؤلفون: Pereira PJS; Citoxlab, Laval, QC, Canada., Pugsley MK; Citoxlab, Laval, QC, Canada., Troncy E; Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, QC, Canada., Tan W; Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, QC, Canada., Pouliot M; Citoxlab, Laval, QC, Canada., Harper C; Avrobio, Cambridge, MA, United States of America., Prefontaine A; Biogen, Cambridge, MA, United States of America., Easter A; Praxis Precision Medicines, Cambridge, MA, United States of America., Wallis R; Safety Pharmacology Consultant, London, United Kingdom., Miraucourt L; Citoxlab, Laval, QC, Canada., Huang H; Citoxlab, Laval, QC, Canada., Accardi MV; Citoxlab, Laval, QC, Canada., Boulay E; Citoxlab, Laval, QC, Canada; Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, QC, Canada., Maghezzi MS; Citoxlab, Laval, QC, Canada., Authier S; Citoxlab, Laval, QC, Canada; Faculty of Veterinary Medicine, Université de Montréal, St-Hyacinthe, QC, Canada. Electronic address: simonauthier@hotmail.com.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2019 Sep - Oct; Vol. 99, pp. 106589. Date of Electronic Publication: 2019 May 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Authier S; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada. Electronic address: authiers@ca.citoxlab.com., Arezzo J; Department of Neuroscience, Albert Einstein College of Medicine, United States; Department of Neurology, Albert Einstein College of Medicine, USA., Pouliot M; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada., Accardi MV; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada., Boulay E; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Troncy E; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Dubuc Mageau M; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Tan W; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Sanfacon A; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Mignault Goulet S; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Paquette D; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2019 Sep - Oct; Vol. 99, pp. 106611. Date of Electronic Publication: 2019 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Authier S; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada. Electronic address: authiers@ca.citoxlab.com., Arezzo J; Department of Neuroscience, Albert Einstein College of Medicine, United States; Department of Neurology, Albert Einstein College of Medicine, USA., Pouliot M; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada., Accardi MV; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada., Boulay E; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Troncy E; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Dubuc Mageau M; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Tan W; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Sanfacon A; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Mignault Goulet S; Groupe de recherche en pharmacologie animale du Québec (GREPAQ), Faculté de médecine vétérinaire, Université de Montréal, Saint-Hyacinthe, QC, Canada., Paquette D; Citoxlab North America, 445 Armand-Frappier, Laval, QC, Canada.

المصدر: Journal of pharmacological and toxicological methods [J Pharmacol Toxicol Methods] 2019 May - Jun; Vol. 97, pp. 52-58. Date of Electronic Publication: 2019 Mar 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 9206091 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-488X (Electronic) Linking ISSN: 10568719 NLM ISO Abbreviation: J Pharmacol Toxicol Methods Subsets: MEDLINE

مواضيع طبية MeSH: Seizures/*chemically induced , Seizures/*physiopathology, Animals ; Behavior, Animal/physiology ; Dogs ; Drug Evaluation, Preclinical/methods ; Electroencephalography/methods ; Macaca fascicularis ; Primates ; Rats ; Rats, Sprague-Dawley ; Retrospective Studies ; Telemetry/methods