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المؤلفون: Jana Flegel, Saad Shaaban, Zhi Jun Jia, Britta Schulte, Yilong Lian, Adrian Krzyzanowski, Malte Metz, Tabea Schneidewind, Fabian Wesseler, Anke Flegel, Alisa Reich, Alexandra Brause, Gang Xue, Minghao Zhang, Lara Dötsch, Isabelle D. Stender, Jan-Erik Hoffmann, Rebecca Scheel, Petra Janning, Fraydoon Rastinejad, Dennis Schade, Carsten Strohmann, Andrey P. Antonchick, Sonja Sievers, Pedro Moura-Alves, Slava Ziegler, Herbert Waldmann
المصدر: Journal of Medicinal Chemistry. 65:16268-16289
مصطلحات موضوعية: Osteoblasts, Receptors, Aryl Hydrocarbon, Drug Discovery, Molecular Medicine, Hedgehog Proteins, Cell Differentiation, Signal Transduction
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المؤلفون: Adrian Krzyzanowski, Lea Marie Esser, Anthony Willaume, Renaud Prudent, Christoph Peter, Peter ‘t Hart, Herbert Waldmann
المصدر: Journal of Medicinal Chemistry. 65:15300-15311
مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Drug Discovery, Molecular Medicine, Enzyme Inhibitors, Adaptor Proteins, Signal Transducing
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المؤلفون: Michael Grigalunas, Sohan Patil, Adrian Krzyzanowski, Axel Pahl, Jana Flegel, Beate Schölermann, Jianing Xie, Sonja Sievers, Slava Ziegler, Herbert Waldmann
المصدر: Chemistry (Weinheim an der Bergstrasse, Germany). 28(67)
مصطلحات موضوعية: Biological Products, Polyketides, Organic Chemistry, Hedgehog Proteins, Antineoplastic Agents, General Chemistry, Catalysis, Biosynthetic Pathways
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5
المصدر: Chembiochem
مصطلحات موضوعية: Protein-Arginine N-Methyltransferases, Peptide, protein–protein interactions, 010402 general chemistry, 01 natural sciences, Biochemistry, Protein–protein interaction, interfaces, TIM barrel, Humans, Molecular Biology, Peptide sequence, Adaptor Proteins, Signal Transducing, chemistry.chemical_classification, biology, 010405 organic chemistry, Chemistry, Methyltransferase complex, Protein arginine methyltransferase 5, Communication, Organic Chemistry, Active site, Signal transducing adaptor protein, Communications, proteins, 0104 chemical sciences, biology.protein, peptides, Molecular Medicine, Protein Processing, Post-Translational, Transcription Factors
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المؤلفون: Mohammad Akbarzadeh, Jana Flegel, Sumersing Patil, Erchang Shang, Rishikesh Narayan, Marcel Buchholzer, Neda S. Kazemein Jasemi, Michael Grigalunas, Adrian Krzyzanowski, Daniel Abegg, Anton Shuster, Marco Potowski, Hacer Karatas, George Karageorgis, Niloufar Mosaddeghzadeh, Mia‐Lisa Zischinsky, Christian Merten, Christopher Golz, Lucas Brieger, Carsten Strohmann, Andrey P. Antonchick, Petra Janning, Alexander Adibekian, Roger S. Goody, Mohammad Reza Ahmadian, Slava Ziegler, Herbert Waldmann
المصدر: Angewandte Chemie International Edition. 61
مصطلحات موضوعية: rho GTP-Binding Proteins, rho Guanine Nucleotide Dissociation Inhibitor alpha, Biological Products, rho-Specific Guanine Nucleotide Dissociation Inhibitors, General Medicine, General Chemistry, Ligands, Catalysis
وصف الملف: application/pdf
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المؤلفون: Ingrid R. Vetter, Hélène Adihou, Darijan Schüler, Arthur T. Porfetye, Adrian Krzyzanowski, Mohammad Akbarzadeh, Herbert Waldmann, Pascal Hommen, Anaïs F. M. Noisier, Peter 't Hart
المصدر: Angewandte Chemie (International Ed. in English)
مصطلحات موضوعية: Scaffold protein, Peptide Inhibitors, Proteases, cyclization, Protein Conformation, Peptide, protein–protein interactions, Alkylation, Crystallography, X-Ray, 010402 general chemistry, Peptides, Cyclic, 01 natural sciences, Catalysis, Protein–protein interaction, chemistry.chemical_compound, Amide, inhibitors, Humans, Amino Acid Sequence, Research Articles, chemistry.chemical_classification, Bicyclic molecule, 010405 organic chemistry, Circular Dichroism, General Chemistry, General Medicine, Combinatorial chemistry, structure-based design, 0104 chemical sciences, chemistry, Drug Design, Mutation, peptides, Thermodynamics, Retinoblastoma-Binding Protein 4, Hydrophobic and Hydrophilic Interactions, Research Article, Cysteine
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المصدر: ChemBioChem. 22:1852-1852
مصطلحات موضوعية: Front cover, Chemistry, Protein arginine methyltransferase 5, Organic Chemistry, Biophysics, Molecular Medicine, Molecular Biology, Biochemistry, Protein–protein interaction
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المؤلفون: Michael Saleeb, Adrian Krzyzanowski, Mikael Elofsson
المصدر: Organic letters. 20(21)
مصطلحات موضوعية: Indole test, chemistry.chemical_compound, chemistry, 010405 organic chemistry, Stereochemistry, Organic Chemistry, Thiophene, Physical and Theoretical Chemistry, Resveratrol, 010402 general chemistry, 01 natural sciences, Biochemistry, 0104 chemical sciences
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المصدر: Tetrahedron. 75:130685
مصطلحات موضوعية: chemistry.chemical_classification, 010405 organic chemistry, Chemistry, Organic Chemistry, Alanine scanning, 010402 general chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, Cyclic peptide, 0104 chemical sciences, Amino acid, Protein–protein interaction, Histone demethylation, Docking (molecular), Drug Discovery, Side chain, Proton NMR