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1
المؤلفون: Essa Hu, Samer Chmait, Thomas T. Nguyen, Amy Porter, Kristin L. Andrews, Silke Miller, Carl Davis, Jennifer R. Allen, Robert M. Rzasa, James J. S. Treanor, Alexander J. Pickrell, Adrie D. Jones, Roxanne Kunz, Daniel B. Horne, Xiaoning Zhao, Matthew R. Kaller, Holger Monenschein, Ning Chen, Heather Eastwood, Jeffrey Clarine, Michael J. Frohn, Andreas Reichelt
المصدر: Bioorganic & Medicinal Chemistry. 22:6570-6585
مصطلحات موضوعية: Models, Molecular, Phosphodiesterase Inhibitors, Stereochemistry, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Humans, Structure–activity relationship, Solubility, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Phosphoric Diester Hydrolases, Chemistry, Organic Chemistry, Bioavailability, Enzyme, Quinolines, Alkoxy group, Molecular Medicine, Lead compound, Ex vivo
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2
المؤلفون: Samer Chmait, Adrie D. Jones, Amy Porter, Kristin L. Andrews, Xiaoning Zhao, Jennifer R. Allen, Shannon Rumfelt, Wenge Zhong, Essa Hu, James R. Falsey, Robert M. Rzasa, Steven W. Louie, James J. S. Treanor, Ning Chen
المصدر: Bioorganic & Medicinal Chemistry Letters. 22:7371-7375
مصطلحات موضوعية: Models, Molecular, Phosphodiesterase Inhibitors, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, Structure-Activity Relationship, Drug Discovery, Humans, Potency, Structure–activity relationship, ATP Binding Cassette Transporter, Subfamily B, Member 1, Molecular Biology, P-glycoprotein, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, biology, Phosphoric Diester Hydrolases, Drug discovery, Organic Chemistry, Phosphodiesterase, Enzyme, chemistry, biology.protein, Molecular Medicine, PDE10A, Efflux, Ethers
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3
المؤلفون: Shou-Hua Xiao, Adam Park, Keith R. Olson, Adrie D. Jones, Stephen W. Young, Danilo Nebalasca, Rommel Mallari, Kun Peng, Tom S. Wehrman, Xiaoning Zhao
المصدر: Journal of biomolecular screening. 13(8)
مصطلحات موضوعية: Arrestins, High-throughput screening, Recombinant Fusion Proteins, Biology, Biochemistry, Analytical Chemistry, Cell Line, Receptors, G-Protein-Coupled, Arrestin, Somatostatin receptor 2, Animals, Humans, Receptors, Somatostatin, Receptor, beta-Arrestins, G protein-coupled receptor, chemistry.chemical_classification, Beta-Arrestins, Reproducibility of Results, beta-Galactosidase, Fusion protein, Enzyme, chemistry, Molecular Medicine, Biological Assay, Peptides, Somatostatin, hormones, hormone substitutes, and hormone antagonists, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7140f579460e439cc3d83cc08117335
https://pubmed.ncbi.nlm.nih.gov/18660457