المؤلفون: Vijayaraj P; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA., Minasyan A; Department of Molecular & Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA., Durra A; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Karumbayaram S; Department of Microbiology, Immunology, and Molecular Genetics, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Stem Cell Research Center, UCLA, Los Angeles, CA 90095, USA., Mehrabi M; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Aros CJ; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Ahadome SD; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Shia DW; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Chung K; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Sandlin JM; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Darmawan KF; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Bhatt KV; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Manze CC; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Paul MK; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Wilkinson DC; Department of Materials Science and Engineering, UCLA, Los Angeles, CA 90095, USA., Yan W; Department of Biology and Biochemistry, UCLA, Los Angeles, CA 90095, USA., Clark AT; Eli and Edythe Broad Stem Cell Research Center, UCLA, Los Angeles, CA 90095, USA; Molecular Cell and Developmental Biology, UCLA, Los Angeles, CA 90095, USA., Rickabaugh TM; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA., Wallace WD; Department of Pathology and Laboratory Medicine, UCLA, Los Angeles, CA 90095, USA., Graeber TG; Department of Molecular & Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA; California NanoSystems Institute, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA., Damoiseaux R; Department of Molecular & Medical Pharmacology, UCLA, Los Angeles, CA 90095, USA; California NanoSystems Institute, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA., Gomperts BN; UCLA Children's Discovery and Innovation Institute, Mattel Children's Hospital UCLA, Department of Pediatrics, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA; Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90095, USA; Eli and Edythe Broad Stem Cell Research Center, UCLA, Los Angeles, CA 90095, USA; UCLA Molecular Biology Institute, UCLA, Los Angeles, CA 90095, USA. Electronic address: bgomperts@mednet.ucla.edu.

المصدر: Cell reports [Cell Rep] 2019 Dec 10; Vol. 29 (11), pp. 3488-3505.e9.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells/*pathology , Pulmonary Fibrosis/*drug therapy , Small Molecule Libraries/*pharmacology, Animals ; Cell Line ; Cells, Cultured ; Drug Discovery/methods ; Female ; Humans ; Induced Pluripotent Stem Cells/drug effects ; Induced Pluripotent Stem Cells/metabolism ; Male ; Mice ; Mice, Inbred C57BL ; Transforming Growth Factor beta/metabolism

المؤلفون: Ahadome SD; Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA., Zhang C; Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA., Tannous E; Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA., Shen J; ScienCell Research Laboratories, Carlsbad, CA 92011, USA., Zheng JJ; Stein Eye Institute, Department of Ophthalmology, David Geffen School of Medicine and Molecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address: jzheng@jsei.ucla.edu.

المصدر: Experimental cell research [Exp Cell Res] 2017 Aug 01; Vol. 357 (1), pp. 116-123. Date of Electronic Publication: 2017 May 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0373226 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2422 (Electronic) Linking ISSN: 00144827 NLM ISO Abbreviation: Exp Cell Res Subsets: MEDLINE

مواضيع طبية MeSH: Dexamethasone/*pharmacology , Trabecular Meshwork/*drug effects , Trabecular Meshwork/*metabolism , Wnt Signaling Pathway/*drug effects, Cells, Cultured ; Extracellular Matrix Proteins/metabolism ; Fibronectins/metabolism ; Humans ; Phenotype ; RNA, Messenger/metabolism

المؤلفون: Ahadome SD; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Ocular Biology and Therapeutics, University College London (UCL) Institute of Ophthalmology, London, United Kingdom., Mathew R; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA., Reyes NJ; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA., Mettu PS; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA., Cousins SW; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA., Calder VL; Department of Ocular Biology and Therapeutics, University College London (UCL) Institute of Ophthalmology, London, United Kingdom., Saban DR; Department of Ophthalmology, Duke University School of Medicine, Durham, North Carolina, USA.; Department of Immunology, Duke University School of Medicine, Durham, North Carolina, USA.

المصدر: JCI insight [JCI Insight] 2016 Aug 04; Vol. 1 (12).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Print Cited Medium: Print ISSN: 2379-3708 (Print) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: PubMed not MEDLINE

المؤلفون: Ahadome SD; Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom., Abraham DJ; Centre for Rheumatology and Connective Tissue Diseases, University College London, Royal Free Campus, London, United Kingdom., Rayapureddi S; Centre for Nephrology, University College London, Royal Free Campus, London, United Kingdom., Saw VP; NIH Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and the UCL Institute of Ophthalmology, London, United Kingdom., Saban DR; Duke University School of Medicine, Departments of Ophthalmology and Immunology, Durham, North Carolina, USA., Calder VL; Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom., Norman JT; Centre for Nephrology, University College London, Royal Free Campus, London, United Kingdom., Ponticos M; Centre for Rheumatology and Connective Tissue Diseases, University College London, Royal Free Campus, London, United Kingdom., Daniels JT; Ocular Biology and Therapeutics, UCL Institute of Ophthalmology, London, United Kingdom., Dart JK; NIH Research (NIHR) Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and the UCL Institute of Ophthalmology, London, United Kingdom.

المصدر: JCI insight [JCI Insight] 2016 Aug 04; Vol. 1 (12), pp. e87001. Date of Electronic Publication: 2016 Aug 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Print ISSN: 2379-3708 (Print) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Aldehyde Dehydrogenase/*antagonists & inhibitors , Cicatrix/*prevention & control , Disulfiram/*pharmacology , Mucous Membrane/*pathology, Adult ; Aged ; Aged, 80 and over ; Animals ; Cells, Cultured ; Conjunctiva/drug effects ; Conjunctiva/physiopathology ; Female ; Fibroblasts/drug effects ; Fibrosis ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Middle Aged ; Pemphigoid, Benign Mucous Membrane ; Tretinoin