نتائج البحث - "Ahmed A. El-Gokha"

المصدر: Molecules; Volume 22; Issue 11; Pages: 1954
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 11, p 1954 (2017)

مصطلحات موضوعية: antiproliferative activity, BALB 3T3 Cells, Stereochemistry, Pharmaceutical Science, Antineoplastic Agents, Chemistry Techniques, Synthetic, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Alkaloids, lcsh:Organic chemistry, Nucleophilic aromatic substitution, Cell Line, Tumor, Drug Discovery, Side chain, Animals, Humans, Physical and Theoretical Chemistry, A549 cell, indolo[2,3-b]quinolone, neocryptolepine, SAR study, aminoalkylamino-substituted, biology, Dibasic acid, Molecular Structure, 010405 organic chemistry, Topoisomerase, Alkaloid, Spectrum Analysis, Organic Chemistry, Quinoline, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry, Chemistry (miscellaneous), Cell culture, biology.protein, Quinolines, Molecular Medicine

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb9afea752a9fbec0962107f9e056ba6

Find this article in full text from ProQuest

5

Synthesis and in Vitro Testing of Antimalarial Activity of Non-natural-Type Neocryptolepines: Structure–Activity Relationship Study of 2,11- and 9,11-Disubstituted 6-Methylindolo[2,3-b]quinolines

المؤلفون: Ryuhei Misumi, Kathryn J. Wicht, Tsutomu Inokuchi, Ibrahim El Tantawy El Sayed, Ahmed A. El Gokha, Ming-qi Wang, Wen-Jie Lu, Ning Wang, Marcel Kaiser, Li Wang, Timothy J. Egan

المصدر: Chemical and Pharmaceutical Bulletin. 61:1282-1290

مصطلحات موضوعية: Strain (chemistry), Stereochemistry, Quinoline, General Chemistry, General Medicine, In vitro, chemistry.chemical_compound, chemistry, Thiourea, Drug Discovery, Urea, Side chain, Structure–activity relationship, Cytotoxicity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3fde7926a44952472c43f03f2a785730
https://doi.org/10.1248/cpb.c13-00639

6

Chemistry of Sulfines, Part V: Chemo- and Stereoselective Synthesis and Hetero-Diels–Alder Reactions of Stable Sulfines

المؤلفون: Ibrahim F. Zeid, Takayuki Kudoh, Omar M. Ali, Ahmed A. El Gokha, Ibrahim El-Sayed

مصطلحات موضوعية: Steric effects, Allylic rearrangement, Chemistry, Organic Chemistry, Diastereomer, chemistry.chemical_element, Biochemistry, Sulfur, Cycloaddition, Inorganic Chemistry, Ab initio quantum chemistry methods, Yield (chemistry), Organic chemistry, Stereoselectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad7e66e126d3824e790928b0e41f07e

7

دورية أكاديمية

Synthesis, biological evaluation and molecular modelling of 3-Formyl-6-isopropylchromone derived thiosemicarbazones as α-glucosidase inhibitors.

المؤلفون: Basri R; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan., Ullah S; Natural and Medical Sciences Research Centre, University of Nizwa, P.O. Box 33, PC 616, Birkat Al Mauz, Nizwa, Sultanate of Oman., Khan A; Natural and Medical Sciences Research Centre, University of Nizwa, P.O. Box 33, PC 616, Birkat Al Mauz, Nizwa, Sultanate of Oman., Mali SN; Department of Pharmaceutical Science and Technology, Birla Institute of Technology, Mesra 835215, India., Abchir O; Laboratory of Analytical and Molecular Chemistry, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca B.P 7955, Morocco., Chtita S; Laboratory of Analytical and Molecular Chemistry, Faculty of Sciences Ben M'Sik, Hassan II University of Casablanca, Casablanca B.P 7955, Morocco., El-Gokha A; Chemistry Department, Faculty of Science, Menoufia University Menoufia, Egypt., Taslimi P; Department of Biotechnology, Faculty of Science, Bartin University, 74100 Bartin, Turkey., Binsaleh AY; Department of Pharmacy Practice, College of Pharmacy, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia., El-Kott AF; Department of Biology, College of Science, King Khalid University, Abha 61421, Saudi Arabia; Department of Zoology, College of Science, Damanhour University, Damanhour 22511, Egypt., Al-Harrasi A; Natural and Medical Sciences Research Centre, University of Nizwa, P.O. Box 33, PC 616, Birkat Al Mauz, Nizwa, Sultanate of Oman. Electronic address: aharrasi@unizwa.edu.om., Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan 60800, Pakistan; Department of Pharmaceutical & Medicinal Chemistry, An der Immenburg 4, D-53121 Bonn, Germany. Electronic address: zahidshafiq@bzu.edu.pk.

المصدر: Bioorganic chemistry [Bioorg Chem] 2023 Oct; Vol. 139, pp. 106739. Date of Electronic Publication: 2023 Jul 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Thiosemicarbazones*/pharmacology , Diabetes Mellitus, Type 2*/drug therapy , Diabetes Mellitus, Type 2*/metabolism, Humans ; Glycoside Hydrolase Inhibitors/chemistry ; alpha-Glucosidases/metabolism ; Molecular Docking Simulation ; Structure-Activity Relationship ; Molecular Structure

View record from ScienceDirect

Full Text Finder

8

دورية أكاديمية

Synthesis and evaluation of novel xanthene-based thiazoles as potential antidiabetic agents.

المؤلفون: Naseem S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan., Shafiq Z; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan.; Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, Bonn, Germany., Taslimi P; Department of Biotechnology, Faculty of Science, Bartin University, Bartin, Turkey.; Department of Chemistry, Faculty of Science, Istinye University, Istanbul, Turkey., Hussain S; Institute of Chemical Sciences, Bahauddin Zakariya University, Multan, Pakistan., Taskin-Tok T; Department of Chemistry, Faculty of Arts and Sciences, Gaziantep University, Gaziantep, Turkey.; Department of Bioinformatics and Computational Biology, Institute of Health Sciences, Gaziantep University, Gaziantep, Turkey., Kisa D; Department of Molecular Biology and Genetics, Faculty of Science, Bartin University, Bartin, Turkey., Saeed A; Department of Chemistry, Quaid-i-Azam University, Islamabad, Pakistan., Temirak A; Chemistry of Natural and Microbial Products Department, Pharmaceutical and Drug Industries Research Institute, National Research Centre, Dokki, Cairo, Egypt., Tahir MN; Department of Physics, University of Sargodha, Sargodha, Pakistan., Rauf K; Department of Chemistry, Govt. Post-Graduate Gordon College, Rawalpindi, Pakistan., El-Gokha A; Chemistry Department, Faculty of Science, Menoufia University, Menoufia, Egypt.

المصدر: Archiv der Pharmazie [Arch Pharm (Weinheim)] 2023 Jan; Vol. 356 (1), pp. e2200356. Date of Electronic Publication: 2022 Oct 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Verlag GmbH & Co. KGaA Country of Publication: Germany NLM ID: 0330167 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4184 (Electronic) Linking ISSN: 03656233 NLM ISO Abbreviation: Arch Pharm (Weinheim) Subsets: MEDLINE

مواضيع طبية MeSH: Butyrylcholinesterase*/metabolism , Acetylcholinesterase*/metabolism, Hypoglycemic Agents/pharmacology ; Molecular Docking Simulation ; Structure-Activity Relationship ; Thiazoles ; Cholinesterase Inhibitors/chemistry ; Glycoside Hydrolases/metabolism

View record at Wiley

Full Text Finder

9

دورية أكاديمية

Synthesis, Biological Evaluation, and In Silico Studies of Novel Coumarin-Based 4 H ,5 H -pyrano[3,2- c ]chromenes as Potent β-Glucuronidase and Carbonic Anhydrase Inhibitors.

المؤلفون: Arif N; Institute of Chemical Sciences, Organic Chemistry Division, Bahauddin Zakariya University, Multan 60800, Pakistan., Shafiq Z; Institute of Chemical Sciences, Organic Chemistry Division, Bahauddin Zakariya University, Multan 60800, Pakistan.; Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany., Mahmood K; Institute of Chemical Sciences, Organic Chemistry Division, Bahauddin Zakariya University, Multan 60800, Pakistan., Rafiq M; Institute of Chemical Sciences, Organic Chemistry Division, Bahauddin Zakariya University, Multan 60800, Pakistan., Naz S; Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Shahzad SA; Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Farooq U; Department of Chemistry, COMSATS University Islamabad, Abbottabad Campus, Abbottabad 22060, Pakistan., Bahkali AH; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Elgorban AM; Department of Botany and Microbiology, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia., Yaqub M; Institute of Chemical Sciences, Organic Chemistry Division, Bahauddin Zakariya University, Multan 60800, Pakistan., El-Gokha A; Department of Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, D-53121 Bonn, Germany.; Chemistry Department, Faculty of Science, Menoufia University, Shebin El-Kom 32512, Egypt.

المصدر: ACS omega [ACS Omega] 2022 Aug 04; Vol. 7 (32), pp. 28605-28617. Date of Electronic Publication: 2022 Aug 04 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101691658 Publication Model: eCollection Cited Medium: Internet ISSN: 2470-1343 (Electronic) Linking ISSN: 24701343 NLM ISO Abbreviation: ACS Omega Subsets: PubMed not MEDLINE

Find this issue from the American Chemical Society

Full Text Finder

10

دورية أكاديمية

Addressing a Trapped High-Energy Water: Design and Synthesis of Highly Potent Pyrimidoindole-Based Glycogen Synthase Kinase-3β Inhibitors.

المؤلفون: Andreev S; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Pantsar T; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, P.O. Box 1627, 70211 Kuopio, Finland., Tesch R; Institute for Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany.; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany., Kahlke N; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., El-Gokha A; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Chemistry Department, Faculty of Science, Menoufia University, Gamal Abdel-Nasser Street, 32511 Shebin El-Kom, Egypt., Ansideri F; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Grätz L; Department of Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany., Romasco J; Department for Life Quality Studies, Alma Mater Studiorum, University of Bologna, Corso D'Augusto 237, 47921 Rimini, Italy., Sita G; Department of Pharmacy and Biotechnology, University of Bologna, Via Irnerio 48, 40126 Bologna, Italy., Geibel C; Institute of Pharmaceutical Sciences, Department of Pharmaceutical (Bio-)Analysis, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Lämmerhofer M; Institute of Pharmaceutical Sciences, Department of Pharmaceutical (Bio-)Analysis, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany., Tarozzi A; Department for Life Quality Studies, Alma Mater Studiorum, University of Bologna, Corso D'Augusto 237, 47921 Rimini, Italy., Knapp S; Institute for Pharmaceutical Chemistry, Goethe University, Max-von-Laue-Straße 9, 60438 Frankfurt am Main, Germany.; Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe University, Max-von-Laue-Straße 15, 60438 Frankfurt am Main, Germany., Laufer SA; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Tübingen Center for Academic Drug Discovery (TüCAD2), Auf der Morgenstelle 8, 72076 Tübingen, Germany., Koch P; Institute of Pharmaceutical Sciences, Department of Medicinal and Pharmaceutical Chemistry, Eberhard Karls University Tübingen, Auf der Morgenstelle 8, 72076 Tübingen, Germany.; Department of Pharmaceutical/Medicinal Chemistry II, Institute of Pharmacy, University of Regensburg, Universitätsstraße 31, 93053 Regensburg, Germany.

المصدر: Journal of medicinal chemistry [J Med Chem] 2022 Jan 27; Vol. 65 (2), pp. 1283-1301. Date of Electronic Publication: 2021 Jul 02.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

Find this issue from the American Chemical Society

تنقيح النتائج