نتائج البحث - "Aidan P. McCann"

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دورية أكاديمية

USP17 is required for trafficking and oncogenic signaling of mutant EGFR in NSCLC cells

المؤلفون: Aidan P. McCann, Peter Smyth, Francesco Cogo, William J. McDaid, Lai Jiang, Jia Lin, Emma Evergren, Roberta E. Burden, Sandra Van Schaeybroeck, Christopher J. Scott, James F. Burrows

المصدر: Cell Communication and Signaling, Vol 16, Iss 1, Pp 1-12 (2018)

مصطلحات موضوعية: Deubiquitinating, Endocytosis, Epidermal growth factor receptor, USP17, NSCLC, Medicine, Cytology, QH573-671

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12964-018-0291-5; https://doaj.org/toc/1478-811X

URL الوصول: https://doaj.org/article/389459c8bc77420cac6802a897ba1482

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USP17 is required for peripheral trafficking of lysosomes

المؤلفون: Jia Lin, Aidan P McCann, Naphannop Sereesongsaeng, Jonathan M Burden, Alhareth A Alsa’d, Roberta E Burden, Ileana Micu, Richard Williams, Sandra Van Schaeybroeck, Emma Evergren, Paul Mullan, Jeremy C Simpson, Christopher J Scott, James F Burrows

المصدر: Lin, J, McCann, A, Sereesongsaeng, N, Burden, J, Alsa'd, A A M, Burden, R, Micu, I, Williams, R, Van Schaeybroeck, S, Evergren, E, Mullan, P, Scott, C & Burrows, J 2022, ' USP17 is required for peripheral trafficking of lysosomes ', EMBO Reports . https://doi.org/10.15252/embr.202051932

مصطلحات موضوعية: Cell Membrane, Genetics, Lysosomes, Molecular Biology, Biochemistry, Cell Proliferation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1620489c446b5d366be14ac3cfc91d68
https://doi.org/10.15252/embr.202051932

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Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature

المؤلفون: Laura A. Ferguson, Michelle K. Greene, Cristina Branco, Caroline J. Barelle, Andrew J. Porter, Christopher J. Scott, Aidan P. McCann, John Steven, Adam Leach, Peter Smyth

المصدر: Leach, A, Smyth, P, Ferguson, L, Steven, J, Greene, M K, Branco, C M, McCann, A P, Porter, A, Barelle, C J & Scott, C J 2020, ' Anti-DLL4 VNAR targeted nanoparticles for targeting of both tumour and tumour associated vasculature ', Nanoscale, vol. 12, no. 27, pp. 14751-14763 . https://doi.org/10.1039/d0nr02962a

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9000d85798e3ba9a09942ab56951fdc9
https://pure.qub.ac.uk/en/publications/bf2ce826-7237-4bae-9ed0-c6f6a9d15d0e

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Star polymers with acid-labile diacetal-based cores synthesized by aqueous RAFT polymerization for intracellular DNA delivery

المؤلفون: Mona Semsarilar, Peter Smyth, Aidan P. McCann, Michael C. Johnston, William J. McDaid, Christopher J. Scott, Thomas J. Gibson, Efrosyni Themistou

المساهمون: Queen's University [Belfast] (QUB)

المصدر: Polymer Chemistry
Polymer Chemistry, Royal Society of Chemistry-RSC, 2020, 11 (2), pp.344-357. ⟨10.1039/c9py00573k⟩
Gibson, T J, Smyth, P, Semsarilar, M, McCann, A P, McDaid, W J, Johnston, M C, Scott, C J & Themistou, E 2019, ' Star polymers with acid-labile diacetal-based cores synthesized by aqueous RAFT polymerization for intracellular DNA delivery ', Polymer Chemistry, vol. 11, no. 2, pp. 344-357 . https://doi.org/10.1039/c9py00573k

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75a97d70f0860651163a344587889053
https://hal.archives-ouvertes.fr/hal-03005850

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Abstract LB096: Development of a next generation ROR1 targeting Protein Drug Conjugate (PDC)

المؤلفون: Chiara Saladino, Andrew C.G. Porter, Estelle McLean, Mark Wappett, Aaron Cranston, Tim Harrison, Stacey Bell, Jennifer Thom, Marina Kovaleva, Aidan P. McCann, Trumper Paul Richard, Graham Cotton, Caroline J. Barelle

المصدر: Cancer Research. 81:LB096-LB096

مصطلحات موضوعية: Cancer Research, Drug discovery, business.industry, medicine.medical_treatment, Cancer, medicine.disease_cause, medicine.disease, Targeted therapy, Oncology, ROR1, medicine, Cancer research, Adenocarcinoma, Carcinogenesis, Ovarian cancer, business, Triple-negative breast cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ce5bf11318a700e628c7657f977339e
https://doi.org/10.1158/1538-7445.am2021-lb096

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Deubiquitylating enzymes in receptor endocytosis and trafficking

المؤلفون: Aidan P. McCann, Christopher J. Scott, Sandra Van Schaeybroeck, James F. Burrows

المصدر: Biochemical Journal. 473:4507-4525

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1104394603ac4245323f3a9b027e5170
https://doi.org/10.1042/bcj20160826

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Abstract 538: Exploiting the properties of VNAR domains for the development of novel efficacious protein drug conjugates targeting the oncofetal protein ROR1

المؤلفون: Marina Kovaleva, Aaron Cranston, Andrew C.G. Porter, Mark Wappett, Estelle McLean, Chiara Saladino, Graham Cotton, Stacey Bell, Andrei Kamenski, Alicia Campion, Trumper Paul Richard, Jennifer Thom, Elisa Persiani, Aidan P. McCann, Caroline J. Barelle, Tim Harrison

المصدر: Cancer Research. 80:538-538

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7c5075206517a9efbcb5c4e86f43aff4
https://doi.org/10.1158/1538-7445.am2020-538

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Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles

المؤلفون: Christopher J. Scott, Michelle K. Greene, Donna M. Small, Peter Smyth, Francesco Cogo, José A. Bengoechea, Aidan P. McCann, Joana Sa Pessoa, Clifford C. Taggart, José Luis Insua, Lai Jiang

المصدر: Jiang, L, Greene, M K, Insua, J L, Sa-Pessoa, J, Small, D M, Smyth, P, McCann, A, Cogo, F, Bengoechea, J A, Taggart, C C & Scott, C J 2018, ' Clearance of intracellular Klebsiella pneumoniae infection using gentamicin-loaded nanoparticles ', Journal of Controlled Release, vol. 279, pp. 316 . https://doi.org/10.1016/j.jconrel.2018.04.040

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::063fb070f88df30bb1b8ed6c0a231601
https://pubmed.ncbi.nlm.nih.gov/29704616

View record from ScienceDirect

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Abstract 222: Novel protein drug conjugates targeting ROR1 through the development and exploitation of a drug discovery platform based on small, engineered VNAR domains

المؤلفون: Trumper Paul Richard, Stacey Bell, Aaron Cranston, Caroline J. Barelle, Andrew C.G. Porter, Andrei Kamenski, Chiara Saladino, Estelle McLean, Marina Kovaleva, Jennifer Thom, Aidan P. McCann, John Steven, Mark Wappett, Graham Cotton, Tim Harrison

المصدر: Cancer Research. 79:222-222

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, biology, Drug discovery, Protein domain, ROR2, Protein engineering, Computational biology, Receptor tyrosine kinase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, 030220 oncology & carcinogenesis, ROR1, biology.protein, Cytotoxic T cell, Antibody

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::83e6aa33418b4a49d7e79448b51f84c1
https://doi.org/10.1158/1538-7445.am2019-222

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