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المؤلفون: Danny V Jeyaraju, Maryam Alapa, Aimee O'Donohue, Ross La Motte-Mohs, Isaac W. Boss, Patrick Hagner, Michael Pourdehnad, Michael R. Burgess, William E. Pierceall, Anjan Thakurta
المصدر: Blood. 140:7070-7071
مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e701a1a20137e965cb14f0ba51773e4
https://doi.org/10.1182/blood-2022-157927 -
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المؤلفون: Peter S. Dragovich, Mingtao He, Leanna Staben, Hongyan Zhang, Melinda M. Mulvihill, Catherine Wilson, Hao Zhou, Tracy Kleinheinz, Binqing Wei, Jianfeng Xin, Nicole Blaquiere, Fanwei Meng, John S. Wai, Susan Kaufman, Liang Liu, Rebecca K. Rowntree, Steven T. Staben, Jing Wang, Katherine R. Kozak, Josefa dela Cruz-Chuh, Zijin Xu, Steven J. Hartman, Robert A. Blake, Xiaoyu Zhu, Sunil Bhakta, Donglu Zhang, Hui Yao, Aimee O'Donohue, Jack Sadowsky, Qi Liu, Pragya Adhikari, Liling Liu, Ying Lu, Thomas H. Pillow, Jinhua Chen, Emel Adaligil, Karen E. Gascoigne
المصدر: Journal of Medicinal Chemistry. 64:2534-2575
مصطلحات موضوعية: BRD4, Immunoconjugates, medicine.drug_class, Cell Cycle Proteins, Monoclonal antibody, 01 natural sciences, 03 medical and health sciences, Ubiquitin, Antigen, Antigens, Neoplasm, In vivo, Drug Discovery, LNCaP, medicine, Humans, Cell Proliferation, 030304 developmental biology, 0303 health sciences, biology, Chemistry, Antibodies, Monoclonal, Dipeptides, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Von Hippel-Lindau Tumor Suppressor Protein, PC-3 Cells, Proteolysis, biology.protein, Molecular Medicine, Oxidoreductases, Heterocyclic Compounds, 3-Ring, Linker, Intracellular, Transcription Factors
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المؤلفون: Steven J. Hartman, Ying Lu, Wentao Wei, Hao Zhou, Geoffrey Del Rosario, Robert A. Blake, Xiaoyu Zhu, Nicholas Corr, Aaron Fullerton, Shang-Fan Yu, Peter S. Dragovich, Jing Wang, Rebecca K. Rowntree, Donglu Zhang, Hui Yao, Emel Adaligil, Fan Jiang, Hongyan Zhang, Jack Sadowsky, John S. Wai, Jinhua Chen, Thomas H. Pillow, Susan Kaufman, Zijin Xu, Katherine R. Kozak, Jeremy Murray, Shenhua Zhang, Leanna Staben, Josefa dela Cruz-Chuh, Pragya Adhikari, Aimee O'Donohue, Tracy Kleinheinz, Liling Liu, Melinda M. Mulvihill, William S. Sawyer, Yongxin Zhao, Binqing Wei
المصدر: Journal of medicinal chemistry. 64(5)
مصطلحات موضوعية: BRD4, Immunoconjugates, Antineoplastic Agents, Cell Cycle Proteins, Mice, SCID, 01 natural sciences, 03 medical and health sciences, Mouse xenograft, Ubiquitin, In vivo, Antigens, Neoplasm, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, 030304 developmental biology, Cell Proliferation, 0303 health sciences, biology, Chemistry, Antibodies, Monoclonal, Dipeptides, Xenograft Model Antitumor Assays, In vitro, 0104 chemical sciences, Cell biology, 010404 medicinal & biomolecular chemistry, Proteasome, Von Hippel-Lindau Tumor Suppressor Protein, Proteolysis, biology.protein, Molecular Medicine, Female, Antibody, Oxidoreductases, Heterocyclic Compounds, 3-Ring, Conjugate, Transcription Factors
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المؤلفون: Douglas D. Leipold, Jinhua Chen, Aimee O'Donohue, Gang Yan, Zijin Xu, Shanique Martin, Gail Lewis Phillips, Josefa dela Cruz-Chuh, Thomas H. Pillow, Changrong He, Fang Fan, John S. Wai, Jintang He, Geoffrey Del Rosario, Carl Ng, Phillip Y. Chu, Shang-Fan Yu, Luna Liu, Dian Su, Guangmin Li, Keyang Xu, Yanli Wang, Katherine R. Kozak, Donglu Zhang, Hui Yao, Jack Sadowsky
المصدر: Bioconjugate Chemistry. 28:2086-2098
مصطلحات موضوعية: 0301 basic medicine, Drug, Immunoconjugates, media_common.quotation_subject, Biomedical Engineering, Pharmaceutical Science, Bioengineering, Peptide, Conjugated system, Protein Engineering, 01 natural sciences, Mice, 03 medical and health sciences, Cell Line, Tumor, Animals, Humans, Cysteine, Disulfides, media_common, Pharmacology, chemistry.chemical_classification, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Protein engineering, Combinatorial chemistry, Small molecule, 0104 chemical sciences, Cell Transformation, Neoplastic, 030104 developmental biology, biology.protein, Antibody, Peptides, Biotechnology, Conjugate
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المؤلفون: Isabel Figueroa, Shang-Fan Yu, Hao Zhou, Ruina Li, Hongyan Zhang, Douglas D. Leipold, Peter S. Dragovich, Karen E. Gascoigne, Amrita V. Kamath, Thomas H. Pillow, Gauri Deshmukh, Pragya Adhikari, Jinhua Chen, John S. Wai, Xinxin Wang, Robert A. Blake, Richard Zang, Xiaoyu Zhu, Tracy Kleinheinz, Chun Sing Li, Donglu Zhang, Geoffrey Del Rosario, Rebecca K. Rowntree, Hui Yao, Melinda M. Mulvihill, Katherine R. Kozak, Jack Sadowsky, Susan Kaufman, Aimee O'Donohue, Cong Wu, Zijin Xu, Brandon Latifi
المصدر: ChemMedChem. 15(1)
مصطلحات موضوعية: Antibody-drug conjugate, Immunoconjugates, Cell Survival, Cell Cycle Proteins, Mice, SCID, Protein degradation, 01 natural sciences, Biochemistry, Heterocyclic Compounds, 4 or More Rings, Proto-Oncogene Proteins c-myc, Mice, In vivo, Cell Line, Tumor, Drug Discovery, Animals, Humans, Lectins, C-Type, General Pharmacology, Toxicology and Pharmaceutics, Pharmacology, Drug Carriers, 010405 organic chemistry, Chemistry, Organic Chemistry, Antibodies, Monoclonal, Surface Plasmon Resonance, Fusion protein, Small molecule, Xenograft Model Antitumor Assays, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Leukemia, Myeloid, Acute, Von Hippel-Lindau Tumor Suppressor Protein, Receptors, Mitogen, Drug delivery, Proteolysis, Biophysics, Molecular Medicine, Female, Linker, Conjugate, Half-Life, Protein Binding, Transcription Factors
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المؤلفون: John S. Wai, Richard Zang, Geoffrey Del Rosario, Rebecca K. Rowntree, Peter S. Dragovich, Ruina Li, Thomas H. Pillow, Gauri Deshmukh, Melinda M. Mulvihill, Xinxin Wang, Pragya Adhikari, Jinhua Chen, Amrita V. Kamath, Hao Zhou, Donglu Zhang, Isabel Figueroa, Shang-Fan Yu, Cong Wu, Chun Sing Li, Douglas D. Leipold, Hongyan Zhang, Hui Yao, Karen E. Gascoigne, Katherine R. Kozak, Brandon Latifi, Tracy Kleinheinz, Jack Sadowsky, Susan Kaufman, Robert A. Blake, Xiaoyu Zhu, Zijin Xu, Aimee O'Donohue
المصدر: ChemMedChem. 15:1-1
مصطلحات موضوعية: Pharmacology, Antibody-drug conjugate, biology, Chemistry, Organic Chemistry, Biochemistry, Molecular biology, Front cover, In vivo, Drug Discovery, Drug delivery, biology.protein, Molecular Medicine, General Pharmacology, Toxicology and Pharmaceutics, Antibody
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المؤلفون: Suzie J. Scales, Josefa Chuh, Sarajane Ross, Elizabeth Luis, Susan D. Spencer, Mark S. Dennis, Glenn Pacheco, Yin Zhang, Jay Tibbitts, Jenny Bostrom, Nidhi Gupta, Dorothy French, Leanne Berry, Aimee O'Donohue, Ron Firestein, Katherine R. Kozak
المصدر: Cancer Research. 74:4494-4494
مصطلحات موضوعية: Cancer Research, Antibody-drug conjugate, biology, business.industry, Cancer, medicine.disease, Humanized antibody, Gemcitabine, Oncology, In vivo, Immunology, medicine, Cancer research, biology.protein, Immunohistochemistry, Mesothelin, Mesothelioma, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a626bf0a5d23e291c76169badf43a254
https://doi.org/10.1158/1538-7445.am2014-4494
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