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المؤلفون: Emily N.J. Ord, Jesse Dawson, Josie C van Kralingen, Lorraine M. Work, I. Mhairi Macrae, John D. McClure, Aisling McFall, Christopher McCabe, Maria Bissett, Thomas F. Coyle
المصدر: Translational Stroke Research
مصطلحات موضوعية: 0301 basic medicine, TOAST subtype, Male, medicine.medical_specialty, Neurology, Microarray, Disease, Rats, Inbred WKY, Brain Ischemia, 03 medical and health sciences, Extracellular Vesicles, 0302 clinical medicine, Internal medicine, Rats, Inbred SHR, microRNA, medicine, Animals, cardiovascular diseases, Stroke, miRNA, Ischemic stroke, business.industry, General Neuroscience, Extracellular vesicle, medicine.disease, 3. Good health, Small vessel disease, Disease Models, Animal, MicroRNAs, 030104 developmental biology, Real-time polymerase chain reaction, Endocrinology, Cerebral Small Vessel Diseases, Original Article, Neurology (clinical), Small vessel, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Lorraine M. Work, Aisling McFall, Stuart A. Nicklin
المصدر: Cellular Signalling
مصطلحات موضوعية: ET-1), endothelin-1, 0301 basic medicine, ARB), angiotensin receptor blocker, Mas receptor, Blood Pressure, Review, MAPKs), mitogen activated protein kinases, Bioinformatics, GPCR), G-protein coupled receptor, Brain Ischemia, Renin-Angiotensin System, 0302 clinical medicine, Ang-(1–7)), angiotensin-(1–7), MrgD), Mas related GPCR type D, BDNF), brain derived neurotrophic factor, Ischaemic stroke, Medicine, pMCAO), permanent middle cerebral artery occlusion, Receptor, Stroke, Cause of death, RAS), renin angiotensin system, ACE), angiotensin converting enzyme, ERK 1/2), extracellular signal related kinase 1/2, AT2R, Ang I), angiotensin I, SHR), spontaneously hypertensive rat, ROS), reactive oxygen species, 030220 oncology & carcinogenesis, C21), compound 21, Hypertension, Renin angiotensin system, AD, Alzheimer's disease, Ang-(1–9), C21, Brain Infarction, Ang-(1–7), 03 medical and health sciences, nNOS), neuronal nitric oxide synthase, tMCAO), transient middle cerebral artery occlusion, Renin–angiotensin system, ACEi), angiotensin converting enzyme inhibitor, Animals, Humans, Ischemic Stroke, Ang-(1–9)), angiotensin-(1–9), Aβ), amyloid β, business.industry, DIZE), diminazene aceturate, NO), nitric oxide, Cell Biology, eNOS), endothelial nitric oxide synthase, NOX), NAD(P)H oxidases, medicine.disease, BBB), blood brain barrier, CBF), cerebral blood flow, BP), blood pressure, Stroke treatment, tPA), tissue plasminogen activator, 030104 developmental biology, Blood pressure, B2R), bradykinin type 2 receptor, AT2R), angiotensin II type 2 receptor, AT1R), angiotensin II type 1 receptor, Ang II), angiotensin II, business, ACE2), angiotensin converting enzyme 2
وصف الملف: application/pdf
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المؤلفون: Brian O. Smith, Amy J. Tibbo, William Fuller, George S. Baillie, Caglar Gök, Aisling McFall, Niall MacQuaide, Gonzalo S. Tejeda, Ruth MacLeod, Godfrey L. Smith, Connor M. Blair, Thomas Brand, Sara Dobi
مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, CAMP signaling, Effector, Second messenger system, Phosphodiesterase, Myocyte, Peptide, Receptor, Intracellular, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::662d72da79fdb83266d8ecdc28d28a77
https://doi.org/10.1101/2020.09.10.290825 -
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المؤلفون: Malcolm R. Macleod, Margaux Aimable, Scott Miners, Matthew MacGregor Sharp, Hilary V O Carswell, Philip M.W. Bath, Ashton Bernard, Emily S. Sena, Claire S. White, Rhian M. Touyz, Patrick G. Kehoe, Tracy D. Farr, Lorraine M. Work, Stefan Szymkowiak, Gillian L. Currie, Catherine N. Hall, Bettina Platt, Andrew N. Clarkson, Gaia Brezzo, Stuart M. Allan, Mark Andrew Good, Roxana O. Carare, Alison D. McNeilly, Alyson A. Miller, Jill H. Fowler, Barry W. McColl, Tuuli M Hietamies, Christopher McCabe, Rebecca C. Trueman, Vincent Mok, Rajesh N. Kalaria, Michael O'Sullivan, Terence J. Quinn, Karen Horsburgh, Atticus H. Hainsworth, Patrick Strangeward, Catherine E. Lawrence, Aisling McFall
المصدر: McFall, A, Hietamies, T M, Bernard, A, Aimable, M, Allan, S M, Bath, P M, Brezzo, G, Carare, R O, Carswell, H V, Clarkson, A N, Currie, G, Farr, T D, Fowler, J, Good, M, Hainsworth, A H, Hall, C, Horsburgh, K, Kalaria, R, Kehoe, P, Lawrence, C, MacLeod, M, McNeilly, A, Miller, A A, Miners, S, Mok, V, O'Sullivan, M, Platt, B, Sena, E, Sharp, M, Strangeward, P, Szymkowiak, S, Touyz, R M, Trueman, R C, White, C, McCabe, C, Work, L M & Quinn, T J 2020, ' UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment: questionnaire and workshop proceedings ', Journal of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678X20910552
Journal of Cerebral Blood Flow & Metabolism
McFall, A, Hietamies, T M, Bernard, A, Aimable, M, Allan, S M, Bath, P M, Brezzo, G, Carare, R O, Carswell, H V, Clarkson, A N, Currie, G, Farr, T D, Fowler, J H, Good, M, Hainsworth, A H, Hall, C, Horsburgh, K, Kalaria, R, Kehoe, P, Lawrence, C, Macleod, M, McColl, B W, McNeilly, A, Miller, A A, Miners, S, Mok, V, O'Sullivan, M, Platt, B, Sena, E S, Sharp, M, Strangeward, P, Szymkowiak, S, Touyz, R M, Trueman, R C, White, C, McCabe, C, Work, L M & Quinn, T J 2020, ' UK consensus on pre-clinical vascular cognitive impairment functional outcomes assessment : questionnaire and workshop proceedings ', Journal of Cerebral Blood Flow and Metabolism . https://doi.org/10.1177/0271678X20910552مصطلحات موضوعية: Opinion, RM, Consensus, Standardization, medicine.medical_treatment, 030204 cardiovascular system & hematology, outcomes, 03 medical and health sciences, Preclinical research, 0302 clinical medicine, Outcome reporting, Surveys and Questionnaires, medicine, Dementia, Animals, Cognitive impairment, vascular cognitive impairment, Medical education, Rehabilitation, questionnaire, Dementia, Vascular, methodology, Recovery of Function, medicine.disease, United Kingdom, Clinical neurology, Disease Models, Animal, Neurology, Research Design, Neurology (clinical), Cardiology and Cardiovascular Medicine, Psychology, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eef0fbd3bfb3e2bea0c06634a444e02
https://strathprints.strath.ac.uk/71920/7/McFall_etal_JCBFM_2020_UK_consensus_on_pre_clinical_vascular_cognitive.pdf -
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المؤلفون: Aisling McFall, Jesse Dawson, Lorraine M. Work
المصدر: Textbook of Vascular Medicine ISBN: 9783030164805
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d383d57b501537c9287f478210c0db27
https://doi.org/10.1007/978-3-030-16481-2_43 -
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المؤلفون: Sarah Morris, David J. Timson, Meilan Huang, Margaret McAuley, Noel Mesa-Torres, Aisling McFall, Angel L. Pey
المصدر: McAuley, M, Mesa-Torres, N, McFall, A, Morris, S, Huang, M, Pey, A L & Timson, D J 2018, ' Improving the activity and stability of human galactokinase for therapeutic and biotechnological applications ', ChemBioChem, vol. 19, no. 10, pp. 1088-1095 . https://doi.org/10.1002/cbic.201800025
مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, Molecular Dynamics Simulation, Protein Engineering, 01 natural sciences, Biochemistry, 03 medical and health sciences, Galactokinase, Enzyme Stability, Monosaccharide, Humans, Point Mutation, Molecular Biology, chemistry.chemical_classification, biology, 010405 organic chemistry, Organic Chemistry, Temperature, Substrate (chemistry), Protein engineering, Enzyme replacement therapy, Enzyme assay, 0104 chemical sciences, 030104 developmental biology, Enzyme, chemistry, biology.protein, Molecular Medicine, Phosphorylation
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80a060287249dc017a825b281bddc40d
https://pure.qub.ac.uk/en/publications/improving-the-activity-and-stability-of-human-galactokinase-for-therapeutic-and-biotechnological-applications(a9936eb8-ecea-49ff-9731-987ec1d3a624).html -
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المصدر: Oral Presentations.
مصطلحات موضوعية: Spontaneously hypertensive rat, business.industry, Renin–angiotensin system, Gene expression, Angiotensin-converting enzyme 2, Ras Peptide, Sham surgery, medicine, Pharmacology, medicine.disease, business, Stroke, Green fluorescent protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e2237483f882cab5637f7f2cb5066dc2
https://doi.org/10.1136/heartjnl-2018-scf.9
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