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1
المؤلفون: Narumi Horita, Daiki Nagamatsu, Yasuhide Morioka, Miki Tanimura, Gaku Sakaguchi, Azusa Nozu, Yasuyoshi Iso, Toshiyuki Kanemasa, Natsue Yamanada, Mikie Hinata, Toshiyuki Asaki, Masayuki Imai, Hidetoshi Matsuda, Kenji Takaya, Osamu Yoshida, Hiromi Nakai, Akira Yukimasa, Shinji Suzuki, Masahiko Soga, Naoki Tsuno, Tomoyuki Ogawa, Hiroki Yamaguchi, Miyuki Yamamoto, Satoko Funaki, Motohiro Fujiu
المصدر: Bioorganic & Medicinal Chemistry. 25:2177-2190
مصطلحات موضوعية: 0301 basic medicine, Analgesic effect, TRPV4, Spectrometry, Mass, Electrospray Ionization, Stereochemistry, Proton Magnetic Resonance Spectroscopy, Guinea Pigs, Clinical Biochemistry, TRPV Cation Channels, Pharmaceutical Science, Biochemistry, Guinea pig, Structure-Activity Relationship, 03 medical and health sciences, Mechanical Hyperalgesia, 0302 clinical medicine, Microsomes, Drug Discovery, Animals, Humans, Pain Management, Molecular Biology, Analgesics, Chemistry, Organic Chemistry, Antagonist, Complete adjuvant, Rats, Thiazoles, 030104 developmental biology, Molecular Medicine, Azabicyclo Compounds, 030217 neurology & neurosurgery
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2
المؤلفون: Gaku Sakaguchi, Tetsuji Ito, Naoki Tsuno, Mikie Hinata, Akira Yukimasa, Yasuyoshi Iso, Satoko Funaki, Daiki Nagamatsu, Miki Tanimura, Miyuki Yamamoto, Tatsuhiko Ueno, Toshiyuki Kanemasa, Yoko Nishimura, Masahiko Soga, Natsue Yamanada, Yasuhide Morioka, Osamu Yoshida, Narumi Horita, Masayuki Imai, Takatsugu Inoue, Yusuke Ichihashi, Hiroki Yamaguchi, Hidetoshi Matsuda
المصدر: Bioorganic & Medicinal Chemistry Letters. 26:4930-4935
مصطلحات موضوعية: 0301 basic medicine, Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Administration, Oral, Biological Availability, TRPV Cation Channels, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Drug Discovery, medicine, Animals, Humans, Structure–activity relationship, Molecular Biology, ADME, Analgesics, Drug discovery, Chemistry, Organic Chemistry, Antagonist, Bioavailability, 030104 developmental biology, Competitive antagonist, Molecular Medicine, Lead compound, 030217 neurology & neurosurgery
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3
المؤلفون: Kyouhei Hayashi, Hiroki Sato, Hirohide Nambu, Kana Watanabe, Hideo Yukioka, Takayuki Okuno, Nobuyuki Tanaka, Masahiko Fujioka, Akira Yukimasa, Yukari Tanaka, Takeshi Chiba, Hideki Tanioka, Naoki Omori, Tamura Yuusuke, Naoki Kouyama, Yuji Nishiura
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:90-95
مصطلحات موضوعية: Y5 Receptor, Agonist, Benzimidazole, medicine.drug_class, Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Pharmacology, Weight Gain, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Oral administration, In vivo, Drug Discovery, medicine, Animals, Cytochrome P-450 Enzyme Inhibitors, Obesity, Sulfones, Molecular Biology, G protein-coupled receptor, Organic Chemistry, Antagonist, Rats, Receptors, Neuropeptide Y, chemistry, Molecular Medicine, Benzimidazoles, Anti-Obesity Agents, Half-Life, Benzimidazole derivative
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4
المؤلفون: Mikie Hinata, Toshiyuki Asaki, Miyuki Yamamoto, Azusa Nozu, Osamu Yoshida, Masayuki Imai, Gaku Sakaguchi, Satoko Funaki, Kenji Takaya, Yasuyoshi Iso, Narumi Horita, Akira Yukimasa, Shinji Suzuki, Naoki Tsuno, Hidetoshi Matsuda, Masahiko Soga, Toshiyuki Kanemasa, Daiki Nagamatsu, Motohiro Fujiu, Hiromi Nakai, Yasuhide Morioka, Hiroki Yamaguchi, Yoko Nishimura, Tetsuji Ito, Tomoyuki Ogawa
المصدر: Bioorganicmedicinal chemistry letters. 26(20)
مصطلحات موضوعية: 0301 basic medicine, TRPV4, Agonist, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Administration, Oral, Biological Availability, TRPV Cation Channels, Pharmacology, Biochemistry, Guinea pig, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, In vivo, Cricetinae, Drug Discovery, medicine, Structure–activity relationship, Animals, Thiazole, Molecular Biology, Chemistry, Drug discovery, Organic Chemistry, Bioavailability, Thiazoles, 030104 developmental biology, Molecular Medicine
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5
المؤلفون: Nobutaka Fujii, Yoshikazu Sasaki, Shinya Oishi, Hirokazu Tamamura, Hideaki Watanabe, Takayoshi Kinoshita, Akira Yukimasa, Junko Watanabe, Akira Otaka
المصدر: The Journal of Organic Chemistry. 69:1634-1645
مصطلحات موضوعية: chemistry.chemical_classification, Samarium, Magnetic Resonance Spectroscopy, Dipeptide, Hydrocarbons, Fluorinated, Molecular Structure, Stereochemistry, Organic Chemistry, Stereoisomerism, Dipeptides, Alkenes, Iodides, Chemical synthesis, Aldehyde, Combinatorial chemistry, chemistry.chemical_compound, chemistry, Aldol reaction, Nucleophile, Aldol condensation, Imines, Chemoselectivity, Reformatsky reaction
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6
المؤلفون: Nobutaka Fujii, Hirokazu Tamamura, Akira Yukimasa, Hideaki Watanabe, Akira Otaka, Shinya Oishi
المصدر: Tetrahedron Letters. 42:5443-5446
مصطلحات موضوعية: chemistry.chemical_compound, Dipeptide, Chemistry, Stereochemistry, Reagent, Organic Chemistry, Drug Discovery, Oxidative phosphorylation, Alkylation, Biochemistry
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7
المؤلفون: M. D. Katsuaki Matsui, M. D. Shinji Ohi, Hironaka Kawasaki, M. D. Kunihiko Miura, M. D. Yutaka Horie, M. D. Tetsurou Hamamoto, P. H. D. Akira Yukimasa
المصدر: Cancer. 77:1991-1997
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, biology, business.industry, Stomach, Cancer, medicine.disease, digestive system diseases, Metastasis, medicine.anatomical_structure, Carcinoembryonic antigen, Lymphatic system, Oncology, Signet ring cell carcinoma, medicine, Carcinoma, biology.protein, Adenocarcinoma, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1d5fb10a7d6f91d2533c9f2742525a84
https://doi.org/10.1002/(sici)1097-0142(19960515)77:10<1991::aid-cncr5>3.0.co;2-k -
8
المؤلفون: Osamu Tanida, Katsuaki Matsui, Mayumi Kurosu, Yousuke Kinoshita, Akira Yukimasa
المصدر: The Journal of the Japanese Society of Clinical Cytology. 35:44-48
مصطلحات موضوعية: Pathology, medicine.medical_specialty, business.industry, Neuroblastoma, Immunochemistry, Medicine, Anatomy, Adult type, business, medicine.disease
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::391dd827308dbd5cb41b19cbbfb42428
https://doi.org/10.5795/jjscc.35.44 -
9
المؤلفون: Kazutaka Sekiguchi, Norihito Sato, Kana Watanabe, Takayuki Okuno, Hideki Tanioka, Yukari Tanaka, Naoki Omori, Hideo Yukioka, Yasunori Yokota, Hirohide Nambu, Akira Yukimasa, Naoki Kouyama
المصدر: Bioorganicmedicinal chemistry letters. 22(5)
مصطلحات موضوعية: Food intake, medicine.medical_specialty, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Body weight, Biochemistry, chemistry.chemical_compound, Eating, Mice, Structure-Activity Relationship, Internal medicine, Drug Discovery, medicine, Animals, Humans, Obesity, Molecular Biology, Benzoxazoles, Organic Chemistry, Body Weight, Antagonist, Hit to lead, Benzoxazole, Rats, Receptors, Neuropeptide Y, Endocrinology, chemistry, Molecular Medicine, Anti-Obesity Agents
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10
المؤلفون: Etsuko Mitsuyama, Akira Otaka, Nobutaka Fujii, Hirokazu Tamamura, Akira Yukimasa, Hideaki Watanabe
المصدر: Tetrahedron Letters. 42:285-287
مصطلحات موضوعية: Reduction (complexity), chemistry.chemical_compound, Dipeptide, Chemistry, Stereochemistry, Reagent, Organic Chemistry, Drug Discovery, Biochemistry