المؤلفون: Zhu J; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Gong Z; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Agricultural High-tech Industrial Demonstration Area of the Yellow River Delta of Shandong Province, Dongying, Shandong 257000, China.; National Technological Innovation Center for Comprehensive Utilization of Saline-Alkali Land, Dongying, Shandong 257000, China., Wang X; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Zhang K; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Ma Y; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Zou H; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Song R; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Zhao H; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Liu Z; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Institute of Agricultural Science and Technology Development (Joint International Research Laboratory of Agriculture and Agri-Product Safety of the Ministry of Education of China), Yangzhou University, Yangzhou, Jiangsu 225009, China.; Jiangsu Co-Innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, Yangzhou, Jiangsu 225009, China., Dong W; College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, China.; Laboratory of Animal Nutrition Metabolic and Poisoning Diseases, College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, Shandong 266109, China.

المصدر: Journal of agricultural and food chemistry [J Agric Food Chem] 2024 Sep 11; Vol. 72 (36), pp. 19667-19679. Date of Electronic Publication: 2024 Sep 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0374755 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5118 (Electronic) Linking ISSN: 00218561 NLM ISO Abbreviation: J Agric Food Chem Subsets: MEDLINE

مواضيع طبية MeSH: Cadmium*/toxicity , Mechanistic Target of Rapamycin Complex 1*/metabolism , Mechanistic Target of Rapamycin Complex 1*/genetics , Apoptosis*/drug effects , Acute Kidney Injury*/metabolism , Acute Kidney Injury*/chemically induced , Acute Kidney Injury*/genetics , Acute Kidney Injury*/drug therapy , Mechanistic Target of Rapamycin Complex 2*/metabolism , Mechanistic Target of Rapamycin Complex 2*/genetics , Epithelial Cells*/drug effects , Epithelial Cells*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Kidney Tubules*/drug effects , Kidney Tubules*/cytology , Kidney Tubules*/metabolism, Animals ; Mice ; Humans ; TOR Serine-Threonine Kinases/metabolism ; TOR Serine-Threonine Kinases/genetics ; Autophagy/drug effects ; Cell Line ; Mice, Inbred C57BL

المؤلفون: Wilson PG; Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S Limestone St, Lexington, KY 40536, United States., Abdelmoti L; Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S Limestone St, Lexington, KY 40536, United States., Gao T; Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S Limestone St, Lexington, KY 40536, United States., Galperin E; Department of Molecular and Cellular Biochemistry, University of Kentucky, 741 S Limestone St, Lexington, KY 40536, United States.

المصدر: Human molecular genetics [Hum Mol Genet] 2024 Sep 03; Vol. 33 (18), pp. 1592-1604.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IRL Press at Oxford University Press Country of Publication: England NLM ID: 9208958 Publication Model: Print Cited Medium: Internet ISSN: 1460-2083 (Electronic) Linking ISSN: 09646906 NLM ISO Abbreviation: Hum Mol Genet Subsets: MEDLINE

مواضيع طبية MeSH: ErbB Receptors*/metabolism , ErbB Receptors*/genetics , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , MAP Kinase Signaling System*/genetics, Humans ; Phosphorylation ; Noonan Syndrome/genetics ; Noonan Syndrome/metabolism ; Signal Transduction/genetics ; Son of Sevenless Proteins/metabolism ; Son of Sevenless Proteins/genetics ; Mutation ; HEK293 Cells ; Intracellular Signaling Peptides and Proteins ; Mitogen-Activated Protein Kinase 3

المؤلفون: Zhang KM; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhao DC; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Li ZY; BGI Research, Shenzhen, 518083, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Wang Y; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Liu JN; Department of Oncology, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shangdong, 264000, China., Du T; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhou L; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Chen YH; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Yu QC; BGI Research, Shenzhen, 518083, China.; College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China., Chen QS; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Cai RZ; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhao ZX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Shan JL; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Hu BX; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhang HL; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Feng GK; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Zhu XF; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Tang J; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.; Department of Breast Oncology, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China., Deng R; State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Collaborative Innovation Center for Cancer Medicine, Guangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and Therapy, Sun Yat-sen University Cancer Center, Guangzhou, 510060, China.

المصدر: Advanced science (Weinheim, Baden-Wurttemberg, Germany) [Adv Sci (Weinh)] 2024 Sep; Vol. 11 (35), pp. e2403592. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: WILEY-VCH Country of Publication: Germany NLM ID: 101664569 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2198-3844 (Electronic) Linking ISSN: 21983844 NLM ISO Abbreviation: Adv Sci (Weinh) Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/metabolism , Breast Neoplasms*/genetics , Breast Neoplasms*/drug therapy , Signal Transduction*/drug effects , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Nucleotidyltransferases*/metabolism , Nucleotidyltransferases*/genetics , Membrane Proteins*/metabolism , Membrane Proteins*/genetics , Drug Resistance, Neoplasm*/genetics, Humans ; Female ; Animals ; Mice ; Receptors, Estrogen/metabolism ; Receptors, Estrogen/genetics ; Feedback, Physiological ; Receptor, ErbB-2/metabolism ; Receptor, ErbB-2/genetics ; Cell Line, Tumor ; Disease Models, Animal

المؤلفون: Song S; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Department of General Surgery, Hunan Provincial People's Hospital (The First Affiliated Hospital of Hunan Normal University), Changsha, 410002, People's Republic of China.; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China., Li B; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Scientific Research Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China., Jin X; Department of Gastrointestinal Surgery, The Eighth Affiliated Hospital of Sun Yat-sen University, Shenzhen, 518107, People's Republic of China., Li H; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China., Wang H; Department of Breast and Thyroid Surgery, Guangzhou Women and Children's Medical Center, Guangzhou, 510623, People's Republic of China., Wang F; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China., He Y; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China.; Department of Gastrointestinal Surgery, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510080, People's Republic of China., Zhang C; Guangdong Provincial Key Laboratory of Digestive Cancer Research, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China. zhchangh@mail.sysu.edu.cn.; Digestive Diseases Center, The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, 518107, People's Republic of China. zhchangh@mail.sysu.edu.cn.

المصدر: Digestive diseases and sciences [Dig Dis Sci] 2024 Sep; Vol. 69 (9), pp. 3261-3275. Date of Electronic Publication: 2024 Jul 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Science + Business Media Country of Publication: United States NLM ID: 7902782 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-2568 (Electronic) Linking ISSN: 01632116 NLM ISO Abbreviation: Dig Dis Sci Subsets: MEDLINE

مواضيع طبية MeSH: Stomach Neoplasms*/genetics , Stomach Neoplasms*/pathology , Stomach Neoplasms*/metabolism , Epithelial-Mesenchymal Transition* , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Signal Transduction*, Humans ; Cell Line, Tumor ; N-Terminal Acetyltransferase E/genetics ; N-Terminal Acetyltransferase E/metabolism ; Animals ; Gene Expression Regulation, Neoplastic ; Carcinogenesis/genetics ; Carcinogenesis/metabolism ; Cell Movement ; Cell Proliferation ; Male ; Mice ; Up-Regulation ; Female ; Mice, Nude ; Prognosis ; N-Terminal Acetyltransferases

المؤلفون: Zhang M; Department of Thoracic and Bone-Soft Tissue Surgery, Hubei Cancer Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan, 430079, China., Wang X; Department of Thoracic and Bone-Soft Tissue Surgery, Hubei Cancer Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan, 430079, China., Zhao J; Department of Orthopedics, Fuyang Traditional Chinese Medicine Orthopedics Hospital, Hangzhou, 311400, Zhejiang, China., Yan J; Department of Orthopedics, Beijing University of Chinese Medicine Affiliated Dongzhimen Hospital, Beijing, 100700, China., He X; Department of Orthopedics, Fuyang Traditional Chinese Medicine Orthopedics Hospital, Hangzhou, 311400, Zhejiang, China., Qin D; Department of Orthopedics, Fuyang Traditional Chinese Medicine Orthopedics Hospital, Hangzhou, 311400, Zhejiang, China., Liang F; Department of Orthopedics, Fuyang Traditional Chinese Medicine Orthopedics Hospital, Hangzhou, 311400, Zhejiang, China. qitk235@163.com., Tong K; Department of Orthopedics, Renmin Hospital of Wuhan University, Wuhan, 430060, China. tongkai0108@163.com., Wang J; Department of Thoracic and Bone-Soft Tissue Surgery, Hubei Cancer Hospital, Tongji Medical College, HuaZhong University of Science and Technology, Wuhan, 430079, China. Wangjjchn@163.com.

المصدر: Molecular biotechnology [Mol Biotechnol] 2024 Sep; Vol. 66 (9), pp. 2241-2253. Date of Electronic Publication: 2023 Aug 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0305 (Electronic) Linking ISSN: 10736085 NLM ISO Abbreviation: Mol Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Osteosarcoma*/genetics , Osteosarcoma*/metabolism , Osteosarcoma*/pathology , Janus Kinase 2*/metabolism , Janus Kinase 2*/genetics , RNA, Circular*/genetics , RNA, Circular*/metabolism , STAT3 Transcription Factor*/metabolism , STAT3 Transcription Factor*/genetics , Signal Transduction* , Phosphatidylinositol 3-Kinases*/metabolism , Phosphatidylinositol 3-Kinases*/genetics , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Cell Proliferation* , Gene Expression Regulation, Neoplastic*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Bone Neoplasms/genetics ; Bone Neoplasms/metabolism ; Bone Neoplasms/pathology ; Apoptosis ; Cell Movement ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Mice, Nude ; Male

المؤلفون: Zhou W; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Cell Biology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA., Ghersi JJ; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.; Pathologies Foetomaternelles et Néonatales, Centre Hospitalier Universitaire Sainte-Justine Research Center, Montréal, QC H3T 1C5, Canada.; Department of Pathology and Cell Biology, Faculty of Medicine, Université de Montréal, Montréal, QC H3T 1J4, Canada., Ristori E; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA., Semanchik N; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA., Prendergast A; Department of Comparative Medicine, Yale zebrafish Research Core, Yale University School of Medicine, New Haven, CT 06510, USA., Zhang R; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA., Carneiro P; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA., Baldissera G; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA., Sessa WC; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA., Nicoli S; Vascular Biology & Therapeutics Program, Yale University School of Medicine, New Haven, CT 06520, USA.; Department of Pharmacology, Yale University School of Medicine, New Haven, CT 06510, USA.; Yale Cardiovascular Research Center, Department of Internal Medicine, Section of Cardiology, Yale University School of Medicine, New Haven, CT 06511, USA.; Department of Genetics, Yale University School of Medicine, New Haven, CT 06510, USA.

المصدر: Development (Cambridge, England) [Development] 2024 Sep 01; Vol. 151 (17). Date of Electronic Publication: 2024 Sep 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Company Of Biologists Limited Country of Publication: England NLM ID: 8701744 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9129 (Electronic) Linking ISSN: 09501991 NLM ISO Abbreviation: Development Subsets: MEDLINE

مواضيع طبية MeSH: Zebrafish*/embryology , Zebrafish*/genetics , Zebrafish*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Zebrafish Proteins*/metabolism , Zebrafish Proteins*/genetics , Receptors, Notch*/metabolism , Receptors, Notch*/genetics , Arteries*/embryology , Arteries*/metabolism, Animals ; Gene Expression Regulation, Developmental ; Endothelial Cells/metabolism ; Signal Transduction ; Mutation/genetics ; Embryo, Nonmammalian/metabolism ; Vascular Endothelial Growth Factor A/metabolism ; Vascular Endothelial Growth Factor A/genetics

المؤلفون: Wang F; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China., Yan X; Ningxia Yinchuan First People's Hospital, Yinchuan, China., Peng X; Ningxia Medical University, Yinchuan, China., Liu D; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China., Bu W; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China., Kang F; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China., Song J; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China., Wang Q; Hepatobiliary Surgery, General Hospital of Ningxia Medical University, No. 804 Shengli Street, Xingqing District, Yinchuan, 750004, Ningxia Hui Autonomous Region, China. wq-6562@163.com.

المصدر: Molecular biotechnology [Mol Biotechnol] 2024 Sep; Vol. 66 (9), pp. 2341-2348. Date of Electronic Publication: 2023 Sep 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: Switzerland NLM ID: 9423533 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-0305 (Electronic) Linking ISSN: 10736085 NLM ISO Abbreviation: Mol Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: TOR Serine-Threonine Kinases*/metabolism , TOR Serine-Threonine Kinases*/genetics , RNA, Circular*/genetics , RNA, Circular*/metabolism , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Cell Movement* , Pancreatic Neoplasms*/genetics , Pancreatic Neoplasms*/pathology , Pancreatic Neoplasms*/metabolism , Signal Transduction* , Neoplasm Invasiveness*/genetics , Adenocarcinoma*/genetics , Adenocarcinoma*/metabolism , Adenocarcinoma*/pathology, Humans ; Cell Line, Tumor ; Gene Expression Regulation, Neoplastic ; Cell Proliferation ; Prognosis

المؤلفون: Pu Y; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China; Department of Neurology, Langzhong People's Hospital, Nanchong, Sichuan, China., Yang J; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China; Affiliated Sichuan Provincial Rehabilitation Hospital of Chengdu University of TCM, Sichuan, China., Pan Q; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China., Li C; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China., Wang L; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China., Xie X; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China., Chen X; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China., Xiao F; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China. Electronic address: feixiao81@126.com., Chen G; Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing Key Laboratory of Neurology, Chongqing, China. Electronic address: GJChen@hospital.cqmu.edu.cn.

المصدر: The Journal of biological chemistry [J Biol Chem] 2024 Aug; Vol. 300 (8), pp. 107530. Date of Electronic Publication: 2024 Jul 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: RGS Proteins*/metabolism , RGS Proteins*/genetics , Aspartic Acid Endopeptidases*/metabolism , Aspartic Acid Endopeptidases*/genetics , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics , Signal Transduction* , Amyloid Precursor Protein Secretases*/metabolism , Amyloid Precursor Protein Secretases*/genetics , Protein Biosynthesis* , Glutathione Transferase*/metabolism , Glutathione Transferase*/genetics, Humans ; Alzheimer Disease/metabolism ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Apoptosis ; Amyloid beta-Peptides/metabolism ; Animals

المؤلفون: Pearson AD; ACCELERATE, Europe, Belgium. Electronic address: andy1pearson@btinternet.com., DuBois SG; Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, USA., Macy ME; Childrens' Hospital, CO, USA., de Rojas T; ACCELERATE, Europe, Belgium., Donoghue M; US Food and Drug Administration, Silver Springs, MD, USA., Weiner S; Children's Cancer Cause, Washington, DC, USA., Knoderer H; Loxo Oncology at Lilly, USA., Bernardi R; Genentech, A Member of the Roche Group, South San Francisco, CA USA., Buenger V; Coalition Against Childhood Cancer (CAC2), Philadelphia, USA., Canaud G; Necker Enfants Malades Hospital, Paris, France., Cantley L; Harvard Medical School, Boston, USA., Chung J; Bayer Healthcare Pharmaceuticals, Whippany, NJ, USA., Fox E; St Jude Children's Research Hospital, TN, USA., Friend J; Kazia Therapeutics, NJ, USA., Glade-Bender J; Memorial Sloan Kettering Cancer Centre, New York, USA., Gorbatchevsky I; Celcuity Inc., Minneapolis, MN, USA., Gore L; Childrens' Hospital, CO, USA., Gupta A; The Hospital for Sick Children (SickKids), Princess Margaret Hospital Toronto, Canada., Hawkins DS; Seattle Children's Hospital, Seattle, USA., Juric D; Massachusetts General Hospital, Boston, USA., Lang LA; Rally Foundation for Childhood Cancer Research, Atlanta, GA, USA., Leach D; National Brain Tumor Society, Newton, MA, USA., Liaw D; Merck Sharp & Dohme, NJ, USA., Lesa G; Paediatric Medicines Office, Scientific Evidence Generation Department, Human Division, European Medicines Agency (EMA), the Netherlands., Ligas F; Paediatric Medicines Office, Scientific Evidence Generation Department, Human Division, European Medicines Agency (EMA), the Netherlands., Lindberg G; The EVAN Foundation, Germantown, MD, USA., Lindberg W; The EVAN Foundation, Germantown, MD, USA., Ludwinski D; Solving Kids' Cancer, New York, USA., Marshall L; The Royal Marsden Hospital, London, UK; The Institute of Cancer Research, London, UK., Mazar A; Actuate Therapeutics Inc., For worth, TX, USA., McDonough J; The Andrew McDonough B+ Foundation, Wilmington, DE, USA., Nysom K; Righospitalet, Copenhagen, Denmark., Ours C; National Human Genome Research Institute/National Institutes of Health, MD, USA., Pappo A; St Jude Children's Research Hospital, TN, USA., Parsons DW; Texas Children's Cancer and Hematology Center, TX, USA., Rosenfeld A; AstraZeneca, Waltham, MA, USA., Scobie N; Zoe4Life, Sullens, Switzerland., Smith M; National Cancer Institute, MD, USA., Taylor D; PORT (Paediatric Oncology Reference Team), London, UK., Weigel B; University of Minnesota, Minneapolis, USA., Weinstein A; Pediatric Brain Tumor Foundation of the US, Atlanta, USA., Karres D; Paediatric Medicines Office, Scientific Evidence Generation Department, Human Division, European Medicines Agency (EMA), the Netherlands., Vassal G; ACCELERATE, Europe, Belgium; Gustave Roussy Cancer Centre, Paris, France.

المصدر: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2024 Aug; Vol. 207, pp. 114145. Date of Electronic Publication: 2024 Jun 08.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005373 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0852 (Electronic) Linking ISSN: 09598049 NLM ISO Abbreviation: Eur J Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/drug therapy , Neoplasms*/genetics , Glycogen Synthase Kinase 3 beta*/antagonists & inhibitors , Glycogen Synthase Kinase 3 beta*/metabolism , Proto-Oncogene Proteins c-akt*/antagonists & inhibitors , Proto-Oncogene Proteins c-akt*/metabolism , TOR Serine-Threonine Kinases*/antagonists & inhibitors, Humans ; Child ; Adolescent ; Phosphoinositide-3 Kinase Inhibitors/therapeutic use ; Phosphoinositide-3 Kinase Inhibitors/pharmacology ; MTOR Inhibitors/therapeutic use ; MTOR Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Protein Kinase Inhibitors/pharmacology ; Antineoplastic Agents/therapeutic use ; Antineoplastic Agents/pharmacology ; Signal Transduction/drug effects

المؤلفون: Xiang J; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Shen X; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Zhang Y; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Zhu Q; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Yin H; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China., Han S; Key Laboratory of Livestock and Poultry Multi-omics, Ministry of Agriculture and Rural Affairs, College of Animal Science and Technology, Sichuan Agricultural University, Chengdu, Sichuan 611130, China; Farm Animal Genetic Resources Exploration and Innovation Key Laboratory of Sichuan Province, Sichuan Agricultural University, Chengdu, Sichuan 611130, China. Electronic address: hanshunshun@sicau.edu.cn.

المصدر: Poultry science [Poult Sci] 2024 Aug; Vol. 103 (8), pp. 103910. Date of Electronic Publication: 2024 May 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0401150 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-3171 (Electronic) Linking ISSN: 00325791 NLM ISO Abbreviation: Poult Sci Subsets: MEDLINE

مواضيع طبية MeSH: Chickens*/genetics , Granulosa Cells*/metabolism , Granulosa Cells*/physiology , MicroRNAs*/genetics , MicroRNAs*/metabolism , Signal Transduction* , Cell Proliferation* , Proto-Oncogene Proteins c-akt*/metabolism , Proto-Oncogene Proteins c-akt*/genetics, Animals ; Female ; Avian Proteins/genetics ; Avian Proteins/metabolism ; Gonadal Steroid Hormones/metabolism ; Gonadal Steroid Hormones/biosynthesis