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المؤلفون: Stefan Schnabel, Christian Mawrin, Felix Sahm, Natalie Waldt, Christoph Kesseler, Josephine Liebich, Peter John, C. Scherlach, Frank Angenstein, I. Erol Sandalcioglu, Elmar Kirches
المصدر: Neuropathology & applied neurobiology 48(2), e12780 (2022). doi:10.1111/nan.12780
مصطلحات موضوعية: Histology, pathology [Meningeal Neoplasms], Cell, pharmacology [Enzyme Inhibitors], AKT1, Biology, medicine.disease_cause, meningioma, Pathology and Forensic Medicine, pharmacology [Pyrimidines], Meningioma, Mice, capivasertib, In vivo, Cell Line, Tumor, antagonists & inhibitors [Proto-Oncogene Proteins c-akt], pathology [Skull Base Neoplasms], Physiology (medical), otorhinolaryngologic diseases, medicine, Animals, Humans, Pyrroles, ddc:610, Enzyme Inhibitors, neoplasms, drug effects [Cell Proliferation], Mutation, genetics [Meningeal Neoplasms], Akt inhibitor AZD5363, Cell growth, genetics [Meningioma], targeted therapy, medicine.disease, nervous system diseases, Pyrimidines, medicine.anatomical_structure, Neurology, Cell culture, Cancer research, pharmacology [Pyrroles], genetics [Proto-Oncogene Proteins c-akt], genetics [Skull Base Neoplasms], Neurology (clinical), Proto-Oncogene Proteins c-akt, pathology [Meningioma]
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المؤلفون: Nina Tunariu, Pasquale Rescigno, Jonathan Welti, Lorna Leonard, Maryou B. Lambros, Niven Mehra, J.S. de Bono, Karen E Swales, Zafeiris Zafeiriou, Diletta Bianchini, Vasiliki Michalarea, D. Nava Rodrigues, Holly Tovey, Nuria Porta, Ruth Riisnaes, Stephen R. Plymate, Florence I. Raynaud, Rachel Slade, Ines Figueiredo, Adam Sharp, Udai Banerji, Penny Flohr, Joaquin Mateo, Susana Miranda, Ruth Ruddle, Michael Kolinsky, Emma Hall, Mateus Crespo, Jun Luo, Suzanne Carreira
المصدر: Annals of Oncology
Annals of Oncology, 31, 619-625
Annals of Oncology, 31, 5, pp. 619-625مصطلحات موضوعية: Male, 0301 basic medicine, Oncology, medicine.medical_specialty, Article, AKT inhibitor, Phosphatidylinositol 3-Kinases, capivasertib, 03 medical and health sciences, chemistry.chemical_compound, Prostate cancer, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Nitriles, Phenylthiohydantoin, medicine, Humans, Enzalutamide, PTEN, Pyrroles, Protein kinase B, PI3K/AKT/mTOR pathway, enzalutamide, biology, Akt inhibitor AZD5363, business.industry, biomarkers, Hematology, prostate cancer, medicine.disease, Rash, AZD5363, Prostatic Neoplasms, Castration-Resistant, Pyrimidines, Treatment Outcome, 030104 developmental biology, chemistry, Tolerability, Urological cancers Radboud Institute for Health Sciences [Radboudumc 15], 030220 oncology & carcinogenesis, Benzamides, biology.protein, medicine.symptom, business, Proto-Oncogene Proteins c-akt
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2805a29633f5113e129c4cb31962d65
https://hdl.handle.net/2066/220752 -
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المؤلفون: Wenjing Wang, Wei Dong, Yuting Xu, Yadong Yan, Chunxiao Liu, Yingqiang Fu, Xu Liu, Cheng Qian, Kaiyuan Zhu
المصدر: Toxicology and applied pharmacology. 429
مصطلحات موضوعية: 3,3'-Diindolylmethane, Indoles, genetic structures, Active Transport, Cell Nucleus, Diindolylmethane, Apoptosis, Breast Neoplasms, Toxicology, chemistry.chemical_compound, Breast cancer, Antineoplastic Combined Chemotherapy Protocols, medicine, Humans, Pyrroles, AC133 Antigen, skin and connective tissue diseases, Protein kinase B, Protein Kinase Inhibitors, Cell Proliferation, Pharmacology, Akt inhibitor AZD5363, Chemistry, Forkhead Box Protein O3, Cancer, medicine.disease, Pyrimidines, Cancer cell, Cancer research, MCF-7 Cells, Neoplastic Stem Cells, Female, sense organs, Proto-Oncogene Proteins c-akt, Signal Transduction
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المؤلفون: Xiao Xiao Li, Chi-On Chan, Shi Jie Zhang, Jeffrey C. To, Dewi Kenneth Rowlands, Ka Yi Man, Amy P. Chiu, Daniel K. W. Mok, Cynthia H. Chiu, Vincent W. Keng, Lilian H. Lo
المصدر: Biochemical and biophysical research communications. 531(2)
مصطلحات موضوعية: 0301 basic medicine, Sympathetic Nervous System, Adipose Tissue, White, Biophysics, Schwann cell, Adipose tissue, Inguinal Canal, White adipose tissue, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, medicine, Adipocytes, Lipolysis, PTEN, Tensin, Animals, Pyrroles, Molecular Biology, Wnt Signaling Pathway, Adiposity, Cell Size, Neurotransmitter Agents, Akt inhibitor AZD5363, biology, Chemistry, Akt/PKB signaling pathway, PTEN Phosphohydrolase, Cell Biology, Cell biology, Up-Regulation, 030104 developmental biology, medicine.anatomical_structure, Pyrimidines, 030220 oncology & carcinogenesis, biology.protein, Schwann Cells, Proto-Oncogene Proteins c-akt
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المؤلفون: Lan Ma, Ruby Yun-Ju Huang, Peter E. Lobie, Vijay Pandey, Alan Prem Kumar, Kanchuragoppal S Rangappa, Qing-Yun Chong, Tao Zhu, Yanxin Wang, Mengyi Zhang, Basappa, Yi-Shiou Chiou
المصدر: ACS Pharmacol Transl Sci
مصطلحات موضوعية: Pharmacology, Cisplatin, education.field_of_study, Akt inhibitor AZD5363, business.industry, Population, Cancer, medicine.disease, Cancer stem cell, Ovarian carcinoma, Cancer cell, medicine, Cancer research, Pharmacology (medical), business, education, Ovarian cancer, medicine.drug
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المؤلفون: Yohei Saito, Suguru Kadomoto, Taito Nakano, Hiroaki Iwamoto, Hiroki Nakata, Tomoyuki Makino, Renato Naito, Kaoru Hiratsuka, Kazuyoshi Shigehara, Kyoko Nakagawa-Goto, Kouji Izumi, Atsushi Mizokami, Hiroshi Yaegashi, Yoshifumi Kadono
المصدر: Cancers, Vol 12, Iss 1, p 89 (2019)
Cancers
Volume 12
Issue 1مصطلحات موضوعية: Cancer Research, Tumor microenvironment, renal cell carcinoma, U937 cell, Akt inhibitor AZD5363, Chemistry, tumor-associated macrophages, Monocyte, Cell migration, chemical and pharmacologic phenomena, hemic and immune systems, migration, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, ccr6, lcsh:RC254-282, Article, ccl20, medicine.anatomical_structure, Oncology, Cell culture, Cancer cell, medicine, Cancer research, Protein kinase B
وصف الملف: application/pdf
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المؤلفون: Andrew Foxley, Daniel Rea, Roberta Littleford, Samreen Ahmed, S Kelly, Anthony Skene, Robert E. Coleman, A Jahan, Jpo Lindermann, Paul Rugman, Kwok-Leung Cheung, Kieran Horgan, Andrew Evans, Jfr Roberston, Martin Pass, Christopher Holcombe, Petra Rauchhaus
المصدر: Cancer Research. 77:P3-06
مصطلحات موضوعية: Cancer Research, Pathology, medicine.medical_specialty, Akt inhibitor AZD5363, medicine.diagnostic_test, business.industry, medicine.disease, Anti tumour, Breast cancer, Oncology, Biopsy, Cancer research, Medicine, business, PI3K/AKT/mTOR pathway
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1043db4782a68e954d04b745a71fd751
https://doi.org/10.1158/1538-7445.sabcs16-p3-06-03 -
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المؤلفون: Jianyun Yan, Heng Wan, Zhengjun Liu, Shun Lu, Lihe Lu, Hao Liu, Qing Chen, Wenjun Liu, Xingxing Yao, Kai Qian, Zhiqi Lin
المصدر: European Journal of Pharmacology. 788:90-97
مصطلحات موضوعية: 0301 basic medicine, Vascular smooth muscle, Gene Expression, Biology, Muscle, Smooth, Vascular, CCN Intercellular Signaling Proteins, Phosphatidylinositol 3-Kinases, 03 medical and health sciences, Cell Movement, Proto-Oncogene Proteins, Humans, Cyclin D1, Phosphorylation, Protein kinase B, PI3K/AKT/mTOR pathway, Cell Proliferation, Pharmacology, Glycogen Synthase Kinase 3 beta, WNT1-inducible-signaling pathway protein 1, Akt inhibitor AZD5363, Akt/PKB signaling pathway, Cell migration, Up-Regulation, Cell biology, 030104 developmental biology, Matrix Metalloproteinase 9, Immunology, Signal transduction, Proto-Oncogene Proteins c-akt, Signal Transduction
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المؤلفون: Yuncheng Zhang, Zhe Li, Ali Faheem, Jun Liu, Chao Wu, Tiantong Sun, Chunyou Li, Yuanwen Zheng, Diantang Zhao
المصدر: Oncology Letters
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, SMG-1, Biology, mTORC2, liver cancer, 03 medical and health sciences, 0302 clinical medicine, medicine, Protein kinase B, PI3K/AKT/mTOR pathway, Akt inhibitor AZD5363, AKT, RPTOR, Cancer, Articles, medicine.disease, AZD5363, Cell biology, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, mTOR, Cancer research, Phosphorylation, Signal transduction
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المؤلفون: Elvira An, Sudhakar Sahoo, Nicole Simms, Andrew Hughes, Melanie Galvin, Richard Marais, Crispin J. Miller, Garry Ashton, John Brognard, Pedro Torres-Ayuso, Matthew G Krebs, Kathryn Simpson, Hui Sun Leong, Kristopher K. Frese, Natalie Cook, Caroline Dive
المصدر: npj Genomic Medicine, Vol 3, Iss 1, Pp 1-7 (2018)
NPJ Genomic Medicine
Torres-ayuso, P, Sahoo, S, Ashton, G, An, E, Simms, N, Galvin, M, Leong, H S, Frese, K K, Simpson, K, Cook, N, Hughes, A, Miller, C J, Marais, R, Dive, C, Krebs, M G & Brognard, J 2018, ' Signaling pathway screening platforms are an efficient approach to identify therapeutic targets in cancers that lack known driver mutations: a case report for a cancer of unknown primary origin ', Genomic Medicine, vol. 3, no. 1, 15 . https://doi.org/10.1038/s41525-018-0055-6مصطلحات موضوعية: 0301 basic medicine, lcsh:QH426-470, lcsh:Medicine, Case Report, Efficacy, 03 medical and health sciences, Genetics, Medicine, Molecular Biology, Protein kinase B, Genetics (clinical), PI3K/AKT/mTOR pathway, Exome sequencing, Manchester Cancer Research Centre, Akt inhibitor AZD5363, business.industry, ResearchInstitutes_Networks_Beacons/mcrc, lcsh:R, Cancer, Precision medicine, medicine.disease, 3. Good health, lcsh:Genetics, 030104 developmental biology, Cancer research, business, Cancer of unknown primary origin
وصف الملف: application/pdf