المؤلفون: Audat SA, Al-Balas QA, Al-Oudat BA, Athamneh MJ, Bryant-Friedrich A

المصدر: Drug Design, Development and Therapy, Vol Volume 16, Pp 873-885 (2022)

مصطلحات موضوعية: anticancer agents, glyoxalase i, structure activity relationship (sar), molecular docking, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/design-synthesis-and-biological-evaluation-of-14-benzenesulfonamide-de-peer-reviewed-fulltext-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/b592084e1dd244cca6d34a07fca3a341

المؤلفون: Al-Oudat BA, Alqudah MA, Audat SA, Al-Balas QA, El-Elimat T, Hassan MA, Frhat IN, Azaizeh MM

المصدر: Drug Design, Development and Therapy, Vol Volume 13, Pp 423-433 (2019)

مصطلحات موضوعية: Chrysin, Design, Synthesis, Cytotoxicity, Caspase 3/7, antiproliferative agents, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.dovepress.com/design-synthesis-and-biologic-evaluation-of-novel-chrysin-derivatives--peer-reviewed-article-DDDT; https://doaj.org/toc/1177-8881

URL الوصول: https://doaj.org/article/f8f77fb96ac743d28f8809040f286a9b

المؤلفون: Al-Oudat BA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan. Electronic address: baoudat@just.edu.jo., Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Balas QA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Audat SA; Department of Chemistry, College of Science and Arts, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Alqudah MAY; Department of Clinical Pharmacy, College of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Hamzah AH; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Hallak RW; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Bedi M; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Bryant-Friedrich A; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.

المصدر: Bioorganic chemistry [Bioorg Chem] 2022 Mar; Vol. 120, pp. 105657. Date of Electronic Publication: 2022 Feb 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Antineoplastic Agents*/pharmacology , Lactoylglutathione Lyase*/chemistry , Lactoylglutathione Lyase*/metabolism, Enzyme Inhibitors/chemistry ; Enzyme Inhibitors/pharmacology ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship

المؤلفون: Al-Oudat BA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan. Electronic address: baoudat@just.edu.jo., Jaradat HM; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Balas QA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Bryant-Friedrich A; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Bedi MF; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2020 Aug 15; Vol. 28 (16), pp. 115608. Date of Electronic Publication: 2020 Jul 04.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Enzyme Inhibitors/*pharmacology , Lactoylglutathione Lyase/*antagonists & inhibitors , Sulfonamides/*pharmacology, Antineoplastic Agents/chemistry ; Enzyme Inhibitors/chemistry ; Humans ; Lactoylglutathione Lyase/metabolism ; Molecular Docking Simulation ; Structure-Activity Relationship ; Sulfonamides/chemistry ; Benzenesulfonamides

المؤلفون: Al-Oudat BA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Ramapuram H; Department of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA., Malla S; Department of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA., Audat SA; Department of Chemistry, College of Science and Arts, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Hussein N; Department of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA., Len JM; Department of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA., Kumari S; Department of Pharmaceutical Sciences, College of Pharmacy, University of Nebraska Medical Center, Omaha, NE 68198, USA., Bedi MF; Department of Medicinal and Biological Chemistry, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA., Ashby CR Jr; Department of Pharmaceutical Sciences, College of Pharmacy & Pharmaceutical Sciences, St. John's University, Queens, NY 11439, USA., Tiwari AK; Department of Pharmacology and Experimental Therapeutics, College of Pharmacy & Pharmaceutical Sciences, University of Toledo, Toledo, OH 43614, USA.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2020 Jul 04; Vol. 25 (13). Date of Electronic Publication: 2020 Jul 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Allyl Compounds/*chemistry , Antineoplastic Agents/*pharmacology , Flavonoids/*chemistry , Hydrazones/*chemistry , Piperazines/*chemistry , Triple Negative Breast Neoplasms/*drug therapy, Antineoplastic Agents/chemistry ; Apoptosis ; Cell Cycle ; Cell Movement ; Cell Proliferation ; Female ; Humans ; Triple Negative Breast Neoplasms/pathology ; Tumor Cells, Cultured

المؤلفون: Audat SA; Department of Chemistry, College of Science and Arts, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Shar'i NA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Oudat BA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Bryant-Friedrich A; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Bedi MF; Department of Medicinal and Biological Chemistry, College of Pharmacy and Pharmaceutical Sciences, University of Toledo, Toledo, OH 43606, USA., Zayed AL; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan., Al-Balas QA; Department of Medicinal Chemistry and Pharmacognosy, Faculty of Pharmacy, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.

المصدر: Molecules (Basel, Switzerland) [Molecules] 2020 Jun 22; Vol. 25 (12). Date of Electronic Publication: 2020 Jun 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 100964009 Publication Model: Electronic Cited Medium: Internet ISSN: 1420-3049 (Electronic) Linking ISSN: 14203049 NLM ISO Abbreviation: Molecules Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*chemistry , Epoxide Hydrolases/*chemistry , Inflammation/*drug therapy , Neoplasms/*drug therapy, Catalytic Domain/drug effects ; Catalytic Domain/genetics ; Drug Design ; Enzyme Inhibitors/therapeutic use ; Epoxide Hydrolases/antagonists & inhibitors ; Epoxide Hydrolases/genetics ; Epoxide Hydrolases/ultrastructure ; Humans ; Inflammation/pathology ; Molecular Docking Simulation ; Neoplasms/pathology ; Structure-Activity Relationship

المؤلفون: Audat SA; Department of Medicinal and Biological Chemistry, The University of Toledo, 2801 W. Bancroft Street, Toledo, Ohio 43606, USA., Love CT, Al-Oudat BA, Bryant-Friedrich AC

المصدر: The Journal of organic chemistry [J Org Chem] 2012 Apr 20; Vol. 77 (8), pp. 3829-37. Date of Electronic Publication: 2012 Apr 11.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

مواضيع طبية MeSH: Carbon/*chemistry , DNA/*chemistry , Deoxyribose/*chemistry , Dideoxynucleosides/*chemistry , Nucleosides/*chemical synthesis , Nucleosides/*chemistry , Nucleotides/*chemical synthesis , Nucleotides/*chemistry , Oligonucleotides/*chemical synthesis , Oligonucleotides/*chemistry, DNA Damage ; Electron Spin Resonance Spectroscopy ; Electrons ; Free Radicals/chemistry ; Light ; Models, Molecular ; Photochemistry ; Spectrophotometry, Ultraviolet