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المؤلفون: Sebastian A; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Abu Rabah RR; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Vunnam S; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Sultan S; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Anbar HS; Department of Pharmaceutical Sciences, Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., El-Gamal R; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt., Tarazi H; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Sarg N; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Alhamad DW; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al Shamma SA; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Shahin AI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Omar HA; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates. Electronic address: alteltaleb@gmail.com., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: drmelgamal2002@gmail.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Aug 05; Vol. 274, pp. 116557. Date of Electronic Publication: 2024 Jun 01.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemical synthesis , Antineoplastic Agents*/chemistry , Drug Design* , Protein Kinase Inhibitors*/pharmacology , Protein Kinase Inhibitors*/chemical synthesis , Protein Kinase Inhibitors*/chemistry , Pyridines*/pharmacology , Pyridines*/chemistry , Pyridines*/chemical synthesis , Cell Proliferation*/drug effects , Drug Screening Assays, Antitumor*, Humans ; Structure-Activity Relationship ; Molecular Structure ; Apoptosis/drug effects ; Dose-Response Relationship, Drug ; Cell Line, Tumor ; Animals ; Molecular Docking Simulation ; Mice

المؤلفون: Elgendy SM; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates., Zaher DM; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Sarg NH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates., Abu Jayab NN; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Medicine, University of Sharjah, Sharjah, United Arab Emirates., Alhamad DW; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates., Omar HA; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates.

المصدر: IUBMB life [IUBMB Life] 2024 Aug; Vol. 76 (8), pp. 577-588. Date of Electronic Publication: 2024 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published for the International Union of Biochemistry and Molecular Biology by Taylor & Francis Country of Publication: England NLM ID: 100888706 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-6551 (Electronic) Linking ISSN: 15216543 NLM ISO Abbreviation: IUBMB Life Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/pathology , Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/metabolism , Carcinoma, Hepatocellular*/genetics , Liver Neoplasms*/pathology , Liver Neoplasms*/drug therapy , Liver Neoplasms*/metabolism , Liver Neoplasms*/genetics , Autophagy*/drug effects , Apoptosis*/drug effects , Cell Proliferation*/drug effects, Humans ; Cell Line, Tumor ; Energy Metabolism/drug effects ; Cell Survival/drug effects ; Signal Transduction/drug effects

المؤلفون: Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates., Dohle W; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom., Anbar HS; Department of Pharmaceutical Sciences, Dubai Pharmacy College for Girls, Dubai 19099, United Arab Emirates., El-Gamal R; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura 35516, Egypt., Leblond B; Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom., Foster PA; Institute of Metabolism and Systems Research, 2(nd) Floor IBR Tower, University of Birmingham, Birmingham B15 2TT, United Kingdom; Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham B15 2TH, United Kingdom., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates., Potter BVL; Medicinal Chemistry and Drug Discovery, Department of Pharmacology, University of Oxford, Mansfield Road, Oxford OX1 3QT, United Kingdom; Medicinal Chemistry, Department of Life Sciences, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom. Electronic address: barry.potter@pharm.ox.ac.uk., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt. Electronic address: drmelgamal2002@gmail.com.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Mar 01; Vol. 101, pp. 117645. Date of Electronic Publication: 2024 Feb 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Raloxifene Hydrochloride*/pharmacology , Breast Neoplasms*/drug therapy , Sulfonic Acids*, Humans ; Female ; Estrogen Receptor alpha ; Cell Line, Tumor ; Enzyme Inhibitors/chemistry ; Steryl-Sulfatase ; Estrogen Receptor Modulators

المؤلفون: Hamad M; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.; College of Health Sciences, University of Sharjah, Sharjah, United Arab Emirates., Al-Marzooq F; College of Medicine and Health Sciences, UAE University, Al Ain, United Arab Emirates., Srinivasulu V; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates., Sulaiman A; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates., Menon V; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates., Ramadan WS; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates., El-Awady R; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates., Al-Tel TH; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, United Arab Emirates.

المصدر: Frontiers in microbiology [Front Microbiol] 2024 Jan 22; Vol. 14, pp. 1336856. Date of Electronic Publication: 2024 Jan 22 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE

المؤلفون: Alkubaisi BO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Aljobowry R; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Ali SM; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Sultan S; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Ravi A; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates. Electronic address: taltal@sharjah.ac.ae., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: malgamal@sharjah.ac.ae.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Dec 05; Vol. 261, pp. 115796. Date of Electronic Publication: 2023 Sep 07.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*, Humans ; Structure-Activity Relationship ; Receptor Protein-Tyrosine Kinases/chemistry ; Receptor Protein-Tyrosine Kinases/metabolism

المؤلفون: Shahin AI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Zaraei SO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Alzuraiqi S; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Abdulateef Z; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Abbas NE; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates.; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates.; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates.; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.

المصدر: Future medicinal chemistry [Future Med Chem] 2023 Oct; Vol. 15 (20), pp. 1885-1901. Date of Electronic Publication: 2023 Oct 10.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101511162 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1756-8927 (Electronic) Linking ISSN: 17568919 NLM ISO Abbreviation: Future Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Oxazoles*/pharmacology , Antitubercular Agents*/pharmacology, Structure-Activity Relationship

المؤلفون: Alkubaisi BO; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Shahin AI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Zenati RA; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Ravi A; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates., Alchami R; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Alkalla M; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Khaled R; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., El-Gamal MI; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al-Tel TH; Research Institute for Medical and Health Sciences, University of Sharjah, Sharjah, 27272, United Arab Emirates.; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates.

المصدر: ChemMedChem [ChemMedChem] 2023 Jul 17; Vol. 18 (14), pp. e202300117. Date of Electronic Publication: 2023 Jun 12.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE

مواضيع طبية MeSH: Biological Products*/pharmacology , Biological Products*/chemistry, Drug Discovery

المؤلفون: Hersi F; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Medicine, University of Sharjah, Sharjah, 27272, United Arab Emirates., Sebastian A; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Tarazi H; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Srinivasulu V; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Mostafa A; Center of Scientific Excellence for Influenza Viruses, Environment and Climate Change Institute, National Research Centre, Giza, 12622, Egypt., Allayeh AK; Virology Lab 176, Water Pollution Research Department, Environment and Climate Change Institute, National Research Centre, Dokki, Giza, 12622, Egypt., Zeng C; Center for Retrovirus Research, The Ohio State University, Columbus, OH, 43210, USA; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, 43210, USA., Hachim IY; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Medicine, University of Sharjah, Sharjah, 27272, United Arab Emirates., Liu SL; Center for Retrovirus Research, The Ohio State University, Columbus, OH, 43210, USA; Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, 43210, USA., Abu-Yousef IA; Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates., Majdalawieh AF; Department of Biology, Chemistry and Environmental Sciences, College of Arts and Sciences, American University of Sharjah, P.O. Box 26666, Sharjah, United Arab Emirates., Zaher DM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Medicine, University of Sharjah, Sharjah, 27272, United Arab Emirates., Omar HA; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt. Electronic address: hanyomar@sharjah.ac.ae., Al-Tel TH; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates. Electronic address: taltal@sharjah.ac.ae.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Jun 05; Vol. 254, pp. 115380. Date of Electronic Publication: 2023 Apr 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Papain*/chemistry , Papain*/genetics , Papain*/metabolism , COVID-19*, Humans ; SARS-CoV-2 ; Protease Inhibitors/pharmacology ; Caco-2 Cells ; Pandemics ; Peptide Hydrolases/metabolism ; Antiviral Agents/pharmacology ; Antiviral Agents/chemistry

SCR Organism: SARS-CoV-2 variants