المؤلفون: Aladesuyi OA; Department of Chemical Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, Johannesburg, South Africa.; Centre for Nanomaterials Science Research, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, Johannesburg, South Africa., Oluwafemi OS; Department of Chemical Sciences, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, Johannesburg, South Africa.; Centre for Nanomaterials Science Research, University of Johannesburg, P.O. Box 17011, Doornfontein 2028, Johannesburg, South Africa.

المصدر: Heliyon [Heliyon] 2023 May 01; Vol. 9 (5), pp. e15904. Date of Electronic Publication: 2023 May 01 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Ltd Country of Publication: England NLM ID: 101672560 Publication Model: eCollection Cited Medium: Print ISSN: 2405-8440 (Print) Linking ISSN: 24058440 NLM ISO Abbreviation: Heliyon Subsets: PubMed not MEDLINE

المؤلفون: Lu S; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA.; Ludwig Institute for Cancer Research, San Diego, CA, USA., Hu J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Arogundade OA; Department of Neurosciences, University of California, San Diego, CA, USA., Goginashvili A; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA.; Ludwig Institute for Cancer Research, San Diego, CA, USA., Vazquez-Sanchez S; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA.; Ludwig Institute for Cancer Research, San Diego, CA, USA., Diedrich JK; The Scripps Research Institute, La Jolla, CA, USA., Gu J; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Blum J; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Oung S; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA.; Ludwig Institute for Cancer Research, San Diego, CA, USA., Ye Q; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA., Yu H; Center for Alzheimer's and Neurodegenerative Diseases, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Department of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.; Peter O'Donnell Jr Brain Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA., Ravits J; Department of Neurosciences, University of California, San Diego, CA, USA., Liu C; Interdisciplinary Research Center on Biology and Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai, China.; University of Chinese Academy of Sciences, Beijing, China., Yates JR 3rd; The Scripps Research Institute, La Jolla, CA, USA., Cleveland DW; Department of Cellular and Molecular Medicine, University of California, San Diego, CA, USA. dcleveland@health.ucsd.edu.; Ludwig Institute for Cancer Research, San Diego, CA, USA. dcleveland@health.ucsd.edu.; Department of Neurosciences, University of California, San Diego, CA, USA. dcleveland@health.ucsd.edu.

المصدر: Nature cell biology [Nat Cell Biol] 2022 Sep; Vol. 24 (9), pp. 1378-1393. Date of Electronic Publication: 2022 Sep 08.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Macmillan Magazines Ltd Country of Publication: England NLM ID: 100890575 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4679 (Electronic) Linking ISSN: 14657392 NLM ISO Abbreviation: Nat Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: DNA-Binding Proteins*/chemistry , DNA-Binding Proteins*/metabolism , Heat-Shock Proteins*/chemistry , Heat-Shock Proteins*/metabolism , Heat-Shock Proteins, Small* , Phase Transition*, Adenosine Triphosphate ; Amyotrophic Lateral Sclerosis/genetics ; Amyotrophic Lateral Sclerosis/metabolism ; HSP70 Heat-Shock Proteins/metabolism ; Humans ; Molecular Chaperones/genetics ; Proteasome Endopeptidase Complex ; RNA/metabolism

المؤلفون: Diaz-Garcia S; Department of Neurosciences, University of California, San Diego, La Jolla, CA, 92093-0670, USA., Ko VI; Department of Neurosciences, University of California, San Diego, La Jolla, CA, 92093-0670, USA., Vazquez-Sanchez S; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, 92093-0670, USA.; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA., Chia R; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892-3707, USA., Arogundade OA; Department of Neurosciences, University of California, San Diego, La Jolla, CA, 92093-0670, USA., Rodriguez MJ; Department of Neurosciences, University of California, San Diego, La Jolla, CA, 92093-0670, USA., Traynor BJ; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, MD, 20892-3707, USA., Cleveland D; Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA, 92093-0670, USA.; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA, USA., Ravits J; Department of Neurosciences, University of California, San Diego, La Jolla, CA, 92093-0670, USA. jravits@ucsd.edu.

المصدر: Acta neuropathologica [Acta Neuropathol] 2021 Dec; Vol. 142 (6), pp. 985-1001. Date of Electronic Publication: 2021 Oct 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0412041 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0533 (Electronic) Linking ISSN: 00016322 NLM ISO Abbreviation: Acta Neuropathol Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*metabolism , Amyotrophic Lateral Sclerosis/*pathology , ELAV-Like Protein 3/*metabolism , Motor Neurons/*metabolism, Cell Nucleus/metabolism ; Humans

المؤلفون: Ho WY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chang JC; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lim K; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Computational Biology Programme, Faculty of Science, National University of Singapore, Singapore., Cazenave-Gassiot A; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore., Nguyen AT; Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA., Foo JC; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore., Muralidharan S; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore., Viera-Ortiz A; Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA., Ong SJM; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Hor JH; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore., Agrawal I; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Hoon S; Molecular Engineering Laboratory, A*STAR Research Entities, Singapore., Arogundade OA; Department of Neurosciences, University of California, San Diego, La Jolla, CA., Rodriguez MJ; Department of Neurosciences, University of California, San Diego, La Jolla, CA., Lim SM; Department of Neurology, and Biomedical Research Institute, Hanyang University College of Medicine, Seoul, South Korea.; Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA., Kim SH; Department of Neurology, and Biomedical Research Institute, Hanyang University College of Medicine, Seoul, South Korea., Ravits J; Department of Neurosciences, University of California, San Diego, La Jolla, CA., Ng SY; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Institute of Molecular and Cell Biology, A*STAR Research Entities, Singapore., Wenk MR; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Singapore Lipidomics Incubator, Life Sciences Institute, National University of Singapore, Singapore., Lee EB; Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA., Tucker-Kellogg G; Computational Biology Programme, Faculty of Science, National University of Singapore, Singapore.; Department of Biological Sciences, National University of Singapore, Singapore., Ling SC; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Healthy Longevity Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Program in Neuroscience and Behavior Disorders, Duke-National University of Singapore Medical School, Singapore.

المصدر: The Journal of cell biology [J Cell Biol] 2021 Sep 06; Vol. 220 (9). Date of Electronic Publication: 2021 Aug 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 0375356 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-8140 (Electronic) Linking ISSN: 00219525 NLM ISO Abbreviation: J Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Cholesterol/*metabolism , DNA-Binding Proteins/*genetics , Frontotemporal Dementia/*genetics , Myelin Sheath/*metabolism , Oligodendroglia/*metabolism , Sterol Regulatory Element Binding Protein 2/*genetics, Animals ; DNA-Binding Proteins/deficiency ; Disease Models, Animal ; Female ; Frontal Lobe/metabolism ; Frontal Lobe/pathology ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/pathology ; Gene Expression Profiling ; Gene Expression Regulation ; Humans ; Hydroxymethylglutaryl-CoA Synthase/genetics ; Hydroxymethylglutaryl-CoA Synthase/metabolism ; Lipid Metabolism/genetics ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Myelin Sheath/pathology ; Oligodendroglia/pathology ; Organoids/metabolism ; Organoids/pathology ; Primary Cell Culture ; Receptors, LDL/genetics ; Receptors, LDL/metabolism ; Signal Transduction ; Spinal Cord/metabolism ; Spinal Cord/pathology ; Sterol Regulatory Element Binding Protein 2/metabolism ; Temporal Lobe/metabolism ; Temporal Lobe/pathology

المؤلفون: Ho R; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: ritchie.ho@cshs.org., Workman MJ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Mathkar P; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Wu K; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Kim KJ; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., O'Rourke JG; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Kellogg M; Illumina Inc., San Diego, CA 92122, USA., Montel V; Illumina Inc., San Diego, CA 92122, USA., Banuelos MG; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Arogundade OA; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA., Diaz-Garcia S; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA., Oheb D; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Huang S; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Khrebtukova I; Illumina Inc., San Diego, CA 92122, USA., Watson L; Illumina Inc., San Diego, CA 92122, USA., Ravits J; Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093, USA., Taylor K; Illumina Inc., San Diego, CA 92122, USA., Baloh RH; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Center for Neural Science and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Svendsen CN; Board of Governors Regenerative Medicine Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address: clive.svendsen@cshs.org.

المصدر: Cell systems [Cell Syst] 2021 Feb 17; Vol. 12 (2), pp. 159-175.e9. Date of Electronic Publication: 2020 Dec 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101656080 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4720 (Electronic) Linking ISSN: 24054712 NLM ISO Abbreviation: Cell Syst Subsets: MEDLINE

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , Induced Pluripotent Stem Cells/*metabolism , Motor Neurons/*metabolism, Animals ; Disease Models, Animal ; Humans ; Mice