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المؤلفون: Jason B. Crawford, Gang Chen, Ernie Mceachern, Gary Bridger, Curtis Harwig, Atsma Bern, Alan Kaller, Renato Skerlj, Ian Baird, Wilson Trevor R, Bryon Carpenter, David Gauthier
المصدر: Organic Process Research & Development. 12:823-830
مصطلحات موضوعية: Organic Chemistry, Imine, chemistry.chemical_element, Zinc, Borohydride, CXCR4, Reductive amination, Chemokine Receptor Antagonist, chemistry.chemical_compound, Sodium borohydride, chemistry, Reagent, Organic chemistry, Physical and Theoretical Chemistry
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2
المؤلفون: Curtis Harwig, Dominique Schols, Gang Chen, Wen Yang, Duane Veale, Susan Nan, Simon P. Fricker, Alan Kaller, Danielle Guay, Jason M. Crawford, Michael Satori, Markus Metz, Yongbao Zhu, Helen Yee, Maria Krumpak, Elyse Bourque, Wilson Trevor R, David Bogucki, Bryon Carpenter, Michael Bey, David C. Leitch, Ron MacFarland, David Gauthier, Ian Baird, Rebecca Wong, Renato T. Skerlj, Jonathan Langille, Yuanxi Zhou, Gary Bridger, Renee Mosi, Ernest J. McEachern, Tuya Ba, Tong-Shuang Li, Krystyna Vocadlo, Veronique Bodart
المصدر: Journal of medicinal chemistry. 56(20)
مصطلحات موضوعية: Receptors, CCR5, Anti-HIV Agents, Cell Survival, hERG, Human immunodeficiency virus (HIV), CHO Cells, Pharmacology, medicine.disease_cause, Imidazolidines, Virus Replication, Benzoates, Chemokine receptor, Structure-Activity Relationship, Cricetulus, Piperidines, In vivo, Cricetinae, Drug Discovery, medicine, Animals, Humans, Cells, Cultured, Cardiotoxicity, biology, Molecular Structure, Chemistry, Imidazoles, In vitro, Receptor selectivity, HEK293 Cells, Biochemistry, Models, Chemical, Drug Design, Lipophilicity, CCR5 Receptor Antagonists, Host-Pathogen Interactions, biology.protein, HIV-1, Leukocytes, Mononuclear, Molecular Medicine
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المؤلفون: Dana Huskens, Ernest J. McEachern, Yongbao Zhu, Helen Yee, Krystyna A. Skupinska, Michael Sartori, Alan Kaller, Gary Bridger, Renato Skerlj, Erik De Clercq, Duane Veale, Ian Baird, Letian Wang, Kate Burrage, Dominique Schols, Wen Yang, Christopher Ronald Smith, Curtis Harwig, Rossana Wauthy
المصدر: Bioorganicmedicinal chemistry letters. 21(5)
مصطلحات موضوعية: DNA Replication, Receptors, CXCR4, Tertiary amine, Anti-HIV Agents, Clinical Biochemistry, Pharmaceutical Science, Butylamines, Virus Replication, Biochemistry, CXCR4, Virus, Heterocyclic Compounds, 1-Ring, Dogs, Pharmacokinetics, Drug Discovery, Structure–activity relationship, Animals, Molecular Biology, biology, Molecular Structure, Chemistry, Organic Chemistry, biology.organism_classification, Virology, humanities, In vitro, Rats, Viral replication, Drug Design, Lentivirus, Aminoquinolines, HIV-1, Molecular Medicine, Benzimidazoles
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