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المؤلفون: Christina N. DiMarco, Anthony L. Gotter, Alan T. Savitz, Joanne Stevens, Joseph G. Bruno, Tamara D. Cabalu, John J. Renger, Jason W. Skudlarek, Pamela L. Tannenbaum, Paul J. Coleman, Scott D. Kuduk, Joseph Brunner, Susan L. Garson, Christopher J. Winrow, Julie A. O'Brien, Charles M. Harrell, Mark H. Pausch
المصدر: Bioorganic & Medicinal Chemistry Letters. 25:2488-2492
مصطلحات موضوعية: Filorexant, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Piperidines, Orexin Receptors, Sleep Initiation and Maintenance Disorders, mental disorders, Drug Discovery, medicine, Animals, Benzamide, Molecular Biology, G protein-coupled receptor, Organic Chemistry, Antagonist, Triazoles, Receptor antagonist, Orexin receptor, Rats, Orexin, Pyrimidines, chemistry, Molecular Medicine, Orexin Receptor Antagonists, Antagonism, Half-Life, Protein Binding, medicine.drug
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المؤلفون: Christopher J. Winrow, Joanne Stevens, Anthony J. Roecker, Charles M. Harrell, Alan T. Savitz, W. Peter Wuelfing, Kerim Babaoglu, Jason W. Skudlarek, Paul J. Coleman, Steven V. Fox, Christina Ng Dimarco, Pamela L. Tannenbaum, Scott D. Kuduk, Susan L. Garson, Joseph G. Bruno, Joseph Brunner, John J. Renger, Tamara D. Cabalu, Anthony L. Gotter, Mark A. Pausch, Julie A. O'Brien
المصدر: Bioorganicmedicinal chemistry letters. 27(6)
مصطلحات موضوعية: Clinical Biochemistry, Dual Orexin Receptor Antagonists, Pharmaceutical Science, Pharmacology, Doras, 01 natural sciences, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, In vivo, mental disorders, Drug Discovery, Animals, Receptor, Molecular Biology, G protein-coupled receptor, Orexins, biology, Molecular Structure, Chemistry, Electromyography, Organic Chemistry, Antagonist, Electroencephalography, biology.organism_classification, 0104 chemical sciences, Orexin, Rats, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Orexin Receptor Antagonists, Antagonism, 030217 neurology & neurosurgery
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المؤلفون: Antonio Cabal, Sherri L. Motzel, Bernard J. Dardzinski, Le T. Duong, Parker D. Mathers, Lynn Cook, Alan T. Savitz, Diane Posavec, Swanand Sardesai, Christopher T. Winkelmann, Donald S. Williams, Thomas N. Hangartner, Eual A. Phillips, Paul J. McCracken, Richa Y. Jayakar, John Szumiloski, Boyd B. Scott, Richard Hargreaves, Jeffrey L. Evelhoch
المصدر: Bone. 56:497-505
مصطلحات موضوعية: medicine.medical_specialty, Histology, Materials science, Physiology, Ovariectomy, Endocrinology, Diabetes and Metabolism, Finite Element Analysis, Osteoporosis, chemistry.chemical_compound, Bone strength, Bone Density, medicine, Animals, Quantitative computed tomography, Bone mineral, Alendronate, Bone Density Conservation Agents, medicine.diagnostic_test, business.industry, Biphenyl Compounds, Radius, medicine.disease, Macaca mulatta, Surgery, Peripheral, chemistry, Ovariectomized rat, Tomography, X-Ray Computed, Nuclear medicine, business, Odanacatib
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4
المؤلفون: Jason M. Uslaner, John J. Renger, Anthony L. Gotter, Paul J. Coleman, Steven V. Fox, Richard Hargreaves, Joanne Stevens, Pamela L. Tannenbaum, Christopher J. Winrow, Scott D. Kuduk, Alan T. Savitz, Spencer J. Tye
مصطلحات موضوعية: 0301 basic medicine, Male, GABA Agents, Polysomnography, Conditioning, Classical, Stimulus (physiology), Doras, behavioral disciplines and activities, 03 medical and health sciences, 0302 clinical medicine, Basic Science, Piperidines, Physiology (medical), Sedative/hypnotic, medicine, Animals, Hypnotics and Sedatives, Wakefulness, Eszopiclone, Sleep Stages, Orexins, Cross-Over Studies, Diazepam, biology, medicine.diagnostic_test, Psychomotor vigilance task, Triazoles, biology.organism_classification, Macaca mulatta, Orexin, 030104 developmental biology, Orexin Receptor Antagonists, Neurology (clinical), Sleep onset, Psychology, Arousal, Sleep, Neuroscience, psychological phenomena and processes, 030217 neurology & neurosurgery, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::807966889585d73e00c8aa7c7dff031e
https://europepmc.org/articles/PMC4763356/ -
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المؤلفون: Pamela L. Tannenbaum, Scott D. Kuduk, Susan L. Garson, Christopher J. Winrow, Spencer J. Tye, Michael J. Marino, Jason M. Uslaner, Paul J. Coleman, John J. Renger, Anthony L. Gotter, Steven V. Fox, Joanne Stevens, Jacquelyn Binns, Alan T. Savitz
المصدر: Frontiers in Behavioral Neuroscience, Vol 8 (2014)
Frontiers in Behavioral Neuroscienceمصطلحات موضوعية: Cognitive Neuroscience, Neutral stimulus, Stimulus (physiology), Doras, lcsh:RC321-571, Behavioral Neuroscience, auditory discrimination, medicine, Original Research Article, Neuroscience of sleep, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, Sleep Stages, biology, biology.organism_classification, medicine.disease, Orexin receptor, Orexin, DORA, Neuropsychology and Physiological Psychology, orexin, hypocretin, Psychology, Arousal, Sleep, Neuroscience, psychological phenomena and processes, Narcolepsy
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المؤلفون: Terrence P. McDonald, Robert A. Hodgson, Anthony L. Gotter, John J. Renger, Mark R Bowlby, Joseph Brunner, Pamela L. Tannenbaum, Richard Hargreaves, Christopher J. Winrow, Jason M. Uslaner, Paul J. Coleman, Spencer J. Tye, Scott D. Kuduk, Susan L. Garson, Lihang Yao, Steven V. Fox, Alan T. Savitz
مصطلحات موضوعية: Male, Zolpidem, Pyridines, Electroencephalography, Pharmacology, Doras, Piperazines, Rats, Sprague-Dawley, Piperidines, medicine, Animals, GABA-A Receptor Agonists, Eszopiclone, Sleep Stages, medicine.diagnostic_test, biology, GABAA receptor, business.industry, musculoskeletal, neural, and ocular physiology, Brain, Triazoles, Quantitative electroencephalography, biology.organism_classification, Orexin receptor, Rats, Psychiatry and Mental health, nervous system, Original Article, Orexin Receptor Antagonists, business, Azabicyclo Compounds, psychological phenomena and processes, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7b6b4cd4df7a9f99727b69dfd369cc6
https://europepmc.org/articles/PMC3799059/ -
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المؤلفون: John J. Renger, Anthony L. Gotter, Christopher E. Cannon, Joseph Brunner, Terrence P. McDonald, Xiaohai Wang, Lihang Yao, Robert A. Hodgson, Christopher J. Winrow, Alan T. Savitz, Pamela L. Tannenbaum, Spencer J. Tye, Scott D. Kuduk, Paul J. Coleman, Steven V. Fox, Susan L. Garson, Mark R. Bowlby, Jason M. Uslaner, Jacquelyn Binns, Joanne Stevens, Donnie Eddins
المصدر: Science translational medicine. 5(179)
مصطلحات موضوعية: Male, Receptors, Neuropeptide, Zolpidem, Time Factors, Pyridines, Administration, Oral, Nerve Tissue Proteins, Pharmacology, Doras, Choice Behavior, Hippocampus, Piperazines, Receptors, G-Protein-Coupled, Rats, Sprague-Dawley, Cognition, Piperidines, Orexin Receptors, Task Performance and Analysis, medicine, Insomnia, Animals, Hypnotics and Sedatives, Attention, Rats, Wistar, Eszopiclone, gamma-Aminobutyric Acid, Diazepam, biology, GABAA receptor, Recognition, Psychology, General Medicine, Triazoles, biology.organism_classification, Sleep in non-human animals, Macaca mulatta, Orexin receptor, Orexin, Rats, Cytoskeletal Proteins, Memory, Short-Term, medicine.symptom, Sleep, Azabicyclo Compounds, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9194da101b9cb09a7c7ebfddc52a16
https://pubmed.ncbi.nlm.nih.gov/23552372 -
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المؤلفون: Bernard J. Dardzinski, Stephen Krause, Mona Purcell, Donald S. Williams, Antonio Cabal, Thomas N. Hangartner, Sangeetha Somayajula, Parker D. Mathers, John Szumiloski, Le T. Duong, Lynn Cook, Jeffrey L. Evelhoch, Sherri L. Motzel, Richa Y. Jayakar, Keenan Brown, Richard Hargreaves, Maureen Pickarski, Alan T. Savitz, Paul J. McCracken, Christopher T. Winkelmann, Boyd B. Scott
المصدر: Bone. 56(2)
مصطلحات موضوعية: musculoskeletal diseases, medicine.medical_specialty, Histology, Bone density, Physiology, Endocrinology, Diabetes and Metabolism, Ovariectomy, Osteoporosis, Bone remodeling, chemistry.chemical_compound, Bone Density, Internal medicine, Medicine, Animals, Femoral neck, Bone mineral, Alendronate, Bone Density Conservation Agents, business.industry, Biphenyl Compounds, hemic and immune systems, Haplorhini, respiratory system, medicine.disease, Spine, Radiography, Endocrinology, medicine.anatomical_structure, chemistry, Ovariectomized rat, Cortical bone, Female, Hip Joint, Bone Remodeling, business, Odanacatib
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المؤلفون: Martha Hotz Vitaterna, Karrie Fitzpatrick, Steven V. Fox, Joseph Brunner, Anthony L. Gotter, Fred W. Turek, He S. Yang, Joshua Millstein, Christopher J. Winrow, Joseph R. Owens, Andrew Kasarskis, Alan T. Savitz, Andrea L. Webber, Victor N. Uebele, Lili Zhou, Jacquelyn Binns, Susan L. Garson, John J. Renger
مصطلحات موضوعية: Male, Sleep Wake Disorders, Sleep induction, Transgene, Polysomnography, Biology, Receptors, Nicotinic, Article, Calcium Channels, Q-Type, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, Mice, Calcium Channels, N-Type, Dopamine receptor D5, Muscarinic acetylcholine receptor, Genetics, medicine, Animals, Receptors, Dopamine D5, Crosses, Genetic, Slow-wave sleep, Receptor, Muscarinic M3, Mice, Inbred BALB C, medicine.diagnostic_test, Calcium Channels, P-Type, Sleep in non-human animals, Rats, Mice, Inbred C57BL, Sleep, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa12eae89fad8d1d540ac1900bbd2e52
https://europepmc.org/articles/PMC3568991/ -
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المؤلفون: John Szumiloski, Le T. Duong, Parker D. Mathers, Paul J. McCracken, Alan T. Savitz, Eual A. Phillips, Richa Y. Jayakar, Antonio Cabal, S. Sardesai, Donald S. Williams
المصدر: Bone. 48:S93-S94
مصطلحات موضوعية: Histology, Physiology, business.industry, Endocrinology, Diabetes and Metabolism, Dentistry, Radius, Finite element method, chemistry.chemical_compound, Bone strength, chemistry, Ovariectomized rat, Medicine, business, Odanacatib, Biomedical engineering