-
1
المؤلفون: William J. Pitts, Alaric J. Dyckman
المصدر: Burger's Medicinal Chemistry and Drug Discovery. :1-43
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::34b67336649fa65a9a6e377f5381c10f
https://doi.org/10.1002/0471266949.bmc203.pub2 -
2
المؤلفون: Alaric J Dyckman, John Macor, Stefan Ruepp, Schieven Gary, Shailesh Dudhgaonkar, Satyanaraya Reddy BhimiReddy, Srinath Subramaniam, Arvind Mathur, David Critton, Shana Posy, Rushith Kumar Anumula, Raju Barre, Anupama Reddy, Subramanya Hegde, Pasunoori Laxman, Sreekantha Ratna Kumar
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cf908c9b46738203425be417fe9b3c6
https://doi.org/10.1021/scimeetings.2c00255 -
3
المؤلفون: Alaric J Dyckman, John Macor, Stefan Ruepp, Gary Leonard Schieven, Shailesh Dudhgaonkar, Satyanaraya Reddy BhimiReddy, Mushkin Basha, Ananta Karmakar, Arvind Mathur, David Critton, Shana Posy, Ramesh Sistla, Rushith Kumar Anumula, Anupama KR Reddy, Vikram Bhogadi, Srinivas Pitani, Ratna K. Sreekantha, Laxman Pasunoori
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::336f946f4a2474d3af406bf065f5e3bc
https://doi.org/10.1021/scimeetings.2c00064 -
4
المؤلفون: Alaric J. Dyckman, Lois D. Lehman-McKeeman, Huadong Sun, Hong Shi, Mary Ellen Cvijic, Ding Ren Shen, Xiaoxia Yang, Michael Yang, Tracy L. Taylor, Hai-Yun Xiao, Zili Xiao, Luisa Salter-Cid, Jian Pang, Percy H. Carter, Paul Levesque, Arvind Mathur, John L. Gilmore, Jenny Xie, T. G. Murali Dhar, Georgia Cornelius, Anthony M. Marino, Kim W. McIntyre, Bethanne M. Warrack
المصدر: Journal of Medicinal Chemistry. 64:1454-1480
مصطلحات موضوعية: Chemistry, Metabolite, Arthritis, Pharmacology, medicine.disease, Ligand (biochemistry), chemistry.chemical_compound, Immune system, Pharmacokinetics, In vivo, Drug Discovery, medicine, Molecular Medicine, Receptor, PK/PD models
-
5
المؤلفون: John L. Gilmore, Kim W. McIntyre, Lois D. Lehman-McKeeman, David Marcoux, Hai-Yun Xiao, Georgia Cornelius, Alaric J. Dyckman, Mary Ellen Cvijic, Jenny Xie, Yang Michael G, T. G. Murali Dhar, Zili Xiao, Tracy L. Taylor, Anthony M. Marino, Ding Ren Shen, Percy H. Carter, Paul Levesque, Arvind Mathur, Huadong Sun, Hong Shi
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Bicyclic molecule, 010405 organic chemistry, Stereochemistry, Aryl, Sphingosine-1-phosphate receptor, Organic Chemistry, Ether, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, Potency, PK/PD models, ED50
-
6
المؤلفون: Lloyd Lecureux, Elizabeth M. Heimrich, Rochelle Thomas, Lois D. Lehman-McKeeman, Hai-Yun Xiao, Georgia Cornelius, Zheng Yang, Alaric J. Dyckman, Anuradha Gupta, Percy H. Carter, Yu-Wen Li, Paul Levesque, Tracy L. Taylor, Zili Xiao, Mary Ellen Cvijic, Arvind Mathur, John L. Gilmore, Lei Gong, Jenny Xie, Marta Dabros, Ding Ren Shen, Xiaoxia Yang, T. G. Murali Dhar, Xia D. Zhou, Yang Michael G, Bala Pragalathan, Huadong Sun, Anthony M. Marino, Hong Shi, Dauh-Rurng Wu, Richard Rampulla, Kim W. McIntyre, Cliff Chen, Luisa Salter-Cid, Bethanne M. Warrack, Celia D’Arienzo, Virna Borowski
المصدر: Journal of Medicinal Chemistry. 62:2265-2285
مصطلحات موضوعية: Agonist, 0303 health sciences, medicine.drug_class, Sphingosine-1-phosphate receptor, Metabolite, Pharmacology, 01 natural sciences, Fingolimod, Partial agonist, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, chemistry.chemical_compound, chemistry, Pharmacokinetics, In vivo, Pharmacodynamics, Drug Discovery, medicine, Molecular Medicine, 030304 developmental biology, medicine.drug
-
7
المؤلفون: John L, Gilmore, Hai-Yun, Xiao, T G Murali, Dhar, Michael, Yang, Zili, Xiao, Xiaoxia, Yang, Tracy L, Taylor, Kim W, McIntyre, Bethanne M, Warrack, Hong, Shi, Paul C, Levesque, Anthony M, Marino, Georgia, Cornelius, Arvind, Mathur, Ding Ren, Shen, Jian, Pang, Mary Ellen, Cvijic, Lois D, Lehman-McKeeman, Huadong, Sun, Jenny, Xie, Luisa, Salter-Cid, Percy H, Carter, Alaric J, Dyckman
المصدر: Journal of medicinal chemistry. 64(3)
مصطلحات موضوعية: Lung Diseases, Male, Serine Endopeptidases, Drug Evaluation, Preclinical, Arthritis, Experimental, Autoimmune Diseases, Rats, Bridged Bicyclo Compounds, Chemotaxis, Leukocyte, Structure-Activity Relationship, Rats, Inbred Lew, Animals, Humans, Myocytes, Cardiac, Proprotein Convertases, Phosphorylation, Bronchoalveolar Lavage Fluid, Biotransformation, Half-Life
-
8
المؤلفون: Shana L. Posy, David A Critton, Stefan Ruepp, Ratna Kumar Sreekantha, Laxman Pasunoori, Dharmpal S. Dodd, Murali Subramanian, Andrew Watson, Percy H. Carter, Honghe Wan, Debarati Mazumder Tagore, Paul Davies, Shailesh Dudhgaonkar, Gary L. Schieven, Ratika Srivastava, Luisa Salter-Cid, Michael A. Poss, Alaric J. Dyckman, Mussari Christopher P
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Autoimmune disease, Toll-like receptor, Innate immune system, 010405 organic chemistry, Organic Chemistry, virus diseases, Context (language use), TLR7, Pharmacology, TLR8, Biology, medicine.disease_cause, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, Autoimmunity, 010404 medicinal & biomolecular chemistry, Drug Discovery, medicine, Receptor
-
9
المؤلفون: Alaric J. Dyckman
المصدر: Journal of Medicinal Chemistry. 60:5267-5289
مصطلحات موضوعية: 0301 basic medicine, Sphingosine, Chemistry, Sphingosine-1-phosphate receptor, Sphingosine metabolism, Computational biology, Sphingolipid, Cell biology, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, Fingolimod Hydrochloride, Drug Discovery, Molecular Medicine, Sphingosine-1-phosphate, Receptor, Clinical evaluation
-
10
المؤلفون: Alaric J. Dyckman, Bang-Chi Chen, Percy H. Carter, Zhiwei Guo, Amarjit Singh, John L. Gilmore, James E. Sheppeck, Animesh Goswami, Huiping Zhang, Xiaoping Hou, Arvind Mathur
المصدر: Organic Process Research & Development. 21:200-207
مصطلحات موضوعية: Agonist, Trifluoromethyl, 010405 organic chemistry, medicine.drug_class, Stereochemistry, Organic Chemistry, Epoxide, Regioselectivity, Alcohol, 010402 general chemistry, 01 natural sciences, 0104 chemical sciences, Benzonitrile, chemistry.chemical_compound, Stereospecificity, chemistry, medicine, Physical and Theoretical Chemistry, Isoxazole