المؤلفون: Telford BJ; InteRNA Technologies BV, Utrecht, The Netherlands., Yahyanejad S; InteRNA Technologies BV, Utrecht, The Netherlands., de Gunst T; InteRNA Technologies BV, Utrecht, The Netherlands., den Boer HC; InteRNA Technologies BV, Utrecht, The Netherlands., Vos RM; InteRNA Technologies BV, Utrecht, The Netherlands., Stegink M; InteRNA Technologies BV, Utrecht, The Netherlands., van den Bosch MTJ; InteRNA Technologies BV, Utrecht, The Netherlands., Alemdehy MF; InteRNA Technologies BV, Utrecht, The Netherlands., van Pinxteren LAH; InteRNA Technologies BV, Utrecht, The Netherlands., Schaapveld RQJ; InteRNA Technologies BV, Utrecht, The Netherlands., Janicot M; InteRNA Technologies BV, Utrecht, The Netherlands.

المصدر: Oncotarget [Oncotarget] 2021 Mar 02; Vol. 12 (5), pp. 422-439. Date of Electronic Publication: 2021 Mar 02 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Impact Journals Country of Publication: United States NLM ID: 101532965 Publication Model: eCollection Cited Medium: Internet ISSN: 1949-2553 (Electronic) Linking ISSN: 19492553 NLM ISO Abbreviation: Oncotarget Subsets: PubMed not MEDLINE

المؤلفون: Will Castro LSEP; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.; Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, Brazil., Pieters W; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., Alemdehy MF; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., Aslam MA; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.; Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan., Buoninfante OA; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., Raaijmakers JA; Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, Netherlands., Pilzecker B; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., van den Berk PCM; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., Te Riele H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands., Medema RH; Division of Cell Biology, Netherlands Cancer Institute, Amsterdam, Netherlands., Pedrosa RC; Department of Biochemistry, Federal University of Santa Catarina, Florianópolis, Brazil., Jacobs H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, Netherlands.

المصدر: Frontiers in pharmacology [Front Pharmacol] 2021 Feb 18; Vol. 12, pp. 596535. Date of Electronic Publication: 2021 Feb 18 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media] Country of Publication: Switzerland NLM ID: 101548923 Publication Model: eCollection Cited Medium: Print ISSN: 1663-9812 (Print) Linking ISSN: 16639812 NLM ISO Abbreviation: Front Pharmacol Subsets: PubMed not MEDLINE

المؤلفون: Aslam MA; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, Multan, Pakistan., Alemdehy MF; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Kwesi-Maliepaard EM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Muhaimin FI; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Caganova M; Max-Delbrück-Center for Molecular Medicine, Berlin, Germany., Pardieck IN; Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., van den Brand T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Welsem T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., de Rink I; Genome Core Facility, Netherlands Cancer Institute, Amsterdam, The Netherlands., Song JY; Division of Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., de Wit E; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, Amsterdam, The Netherlands., Arens R; Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands., Jacobs H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Leeuwen F; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.; Department of Medical Biology, Amsterdam UMC, Location AMC, University of Amsterdam, Amsterdam, The Netherlands.

المصدر: EMBO reports [EMBO Rep] 2021 Feb 03; Vol. 22 (2), pp. e51184. Date of Electronic Publication: 2021 Jan 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation* , Histone-Lysine N-Methyltransferase*/genetics , Histones*/genetics , Histones*/metabolism , Methyltransferases*/genetics , Methyltransferases*/metabolism, B-Lymphocytes/*cytology, Animals ; Epigenesis, Genetic ; Mice

المؤلفون: van den Bosch MTJ; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Yahyanejad S; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Alemdehy MF; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Telford BJ; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., de Gunst T; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., den Boer HC; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Vos RM; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Stegink M; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., van Pinxteren LAH; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Schaapveld RQJ; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands., Janicot M; InteRNA Technologies BV, Yalelaan 62, 3584 CM Utrecht, the Netherlands.

المصدر: Molecular therapy. Nucleic acids [Mol Ther Nucleic Acids] 2021 Jan 26; Vol. 23, pp. 1161-1171. Date of Electronic Publication: 2021 Jan 26 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101581621 Publication Model: eCollection Cited Medium: Print ISSN: 2162-2531 (Print) Linking ISSN: 21622531 NLM ISO Abbreviation: Mol Ther Nucleic Acids Subsets: PubMed not MEDLINE

المؤلفون: Aslam MA; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.; Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, 60800 Multan, Pakistan., Alemdehy MF; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Hao B; Department of Pathology, New York University School of Medicine, New York, NY 10016., Krijger PHL; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center Utrecht, 3584 CT Utrecht, The Netherlands., Pritchard CEJ; Mouse Clinic for Cancer and Aging Transgenic Facility, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., de Rink I; Genome Core Facility, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Muhaimin FI; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Nurzijah I; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., van Baalen M; Flow Cytometry Facility, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Kerkhoven RM; Genome Core Facility, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., van den Berk PCM; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands., Skok JA; Department of Pathology, New York University School of Medicine, New York, NY 10016., Jacobs H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands; h.jacobs@nki.nl.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Dec 08; Vol. 117 (49), pp. 31343-31352. Date of Electronic Publication: 2020 Nov 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: B-Lymphocytes/*cytology , B-Lymphocytes/*metabolism , Immunoglobulin Heavy Chains/*genetics , Immunoglobulin Heavy Chains/*metabolism, Alleles ; Animals ; Biomarkers/metabolism ; Genetic Loci ; Mice, Inbred C57BL ; Precursor Cells, B-Lymphoid/cytology ; Precursor Cells, B-Lymphoid/immunology ; RNA, Messenger/genetics ; RNA, Messenger/metabolism ; Reproducibility of Results

المؤلفون: Kwesi-Maliepaard EM; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Aslam MA; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands.; Institute of Molecular Biology and Biotechnology, Bahauddin Zakariya University, 60800 Multan, Pakistan., Alemdehy MF; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., van den Brand T; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., McLean C; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Vlaming H; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., van Welsem T; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Korthout T; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Lancini C; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Hendriks S; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., Ahrends T; Division of Tumor Biology and Immunology, Oncode Institute, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., van Dinther D; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center (UMC), Vrije Universiteit Amsterdam, 1081HV Amsterdam, The Netherlands., den Haan JMM; Department of Molecular Cell Biology and Immunology, Amsterdam University Medical Center (UMC), Vrije Universiteit Amsterdam, 1081HV Amsterdam, The Netherlands., Borst J; Division of Tumor Biology and Immunology, Oncode Institute, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., de Wit E; Division of Gene Regulation, Oncode Institute, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands., van Leeuwen F; Division of Gene Regulation, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands; fred.v.leeuwen@nki.nl h.jacobs@nki.nl.; Department of Medical Biology, Amsterdam UMC, University of Amsterdam, 1105AZ Amsterdam, The Netherlands., Jacobs H; Division of Tumor Biology and Immunology, Netherlands Cancer Institute, 1066CX Amsterdam, The Netherlands; fred.v.leeuwen@nki.nl h.jacobs@nki.nl.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Aug 25; Vol. 117 (34), pp. 20706-20716. Date of Electronic Publication: 2020 Aug 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes/*metabolism , Histone-Lysine N-Methyltransferase/*metabolism, Animals ; Antigens, Differentiation/genetics ; Antigens, Differentiation/metabolism ; Cell Differentiation/genetics ; Epigenesis, Genetic/genetics ; Epigenomics ; Female ; Histone Methyltransferases/metabolism ; Histone-Lysine N-Methyltransferase/physiology ; Histones/metabolism ; Male ; Methyltransferases/metabolism ; Mice

المؤلفون: Vlaming H; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., McLean CM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Korthout T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Alemdehy MF; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Hendriks S; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Lancini C; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Palit S; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Klarenbeek S; Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Kwesi-Maliepaard EM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Molenaar TM; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Hoekman L; Experimental Animal Pathology, Netherlands Cancer Institute, Amsterdam, The Netherlands., Schmidlin TT; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute for Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands., Altelaar AM; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Utrecht Institute for Pharmaceutical Sciences, Utrecht University and Netherlands Proteomics Centre, Utrecht, The Netherlands.; Proteomics Facility, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Welsem T; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Dannenberg JH; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands., Jacobs H; Division of Tumor Biology & Immunology, Netherlands Cancer Institute, Amsterdam, The Netherlands., van Leeuwen F; Division of Gene Regulation, Netherlands Cancer Institute, Amsterdam, The Netherlands.

المصدر: The EMBO journal [EMBO J] 2019 Jul 15; Vol. 38 (14), pp. e101564. Date of Electronic Publication: 2019 Jun 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE

مواضيع طبية MeSH: Histone Deacetylase 1/*genetics , Histone Deacetylase 2/*metabolism , Histone-Lysine N-Methyltransferase/*genetics , Histones/*metabolism , Lymphoma/*metabolism , Thymus Neoplasms/*metabolism, Acetylation ; Animals ; Cell Line, Tumor ; Gene Deletion ; Histone Deacetylases/genetics ; Humans ; Lymphoma/genetics ; Methylation ; Mice ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/genetics ; Saccharomyces cerevisiae Proteins/metabolism ; Thymus Neoplasms/genetics

المؤلفون: Aslam MA; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Alemdehy MF; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Pritchard CEJ; Mouse Clinic for Cancer and Aging research (MCCA) Transgenic Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Song JY; Division of Experimental Animal Pathology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Muhaimin FI; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Wijdeven RH; Department of Chemical Immunology, Leiden University Medical Center LUMC, RC Leiden, The Netherlands., Huijbers IJ; Mouse Clinic for Cancer and Aging research (MCCA) Transgenic Facility, The Netherlands Cancer Institute, Amsterdam, The Netherlands., Neefjes J; Department of Chemical Immunology, Leiden University Medical Center LUMC, RC Leiden, The Netherlands., Jacobs H; Division of Tumor Biology & Immunology, The Netherlands Cancer Institute, Amsterdam, The Netherlands.

المصدر: PloS one [PLoS One] 2019 Jan 10; Vol. 14 (1), pp. e0210526. Date of Electronic Publication: 2019 Jan 10 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: DNA Breaks, Double-Stranded*, Apoptosis Regulatory Proteins/*physiology , DNA Topoisomerases, Type II/*metabolism, Animals ; Apoptosis ; Apoptosis Regulatory Proteins/genetics ; B-Lymphocytes/cytology ; B-Lymphocytes/metabolism ; CRISPR-Cas Systems ; Caspase 3/metabolism ; Cell Proliferation ; Cells, Cultured ; DNA Damage ; DNA Repair ; Immunoglobulin Class Switching ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; T-Lymphocytes/cytology ; T-Lymphocytes/metabolism

المؤلفون: Alemdehy MF; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands.; Division of Biological Stress Response, The Netherlands Cancer Institute, Amsterdam, The Netherlands., de Looper HW; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Kavelaars FG; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Sanders MA; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Hoogenboezem R; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Löwenberg B; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Valk PJ; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Touw IP; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands., Erkeland SJ; Department of Hematology, Erasmus University Medical Center Cancer Institute, Rotterdam, The Netherlands.; Department of Immunology, Erasmus University Medical Center, Rotterdam, The Netherlands.

المصدر: Leukemia [Leukemia] 2016 Nov; Vol. 30 (11), pp. 2238-2241. Date of Electronic Publication: 2016 Jun 04.

نوع المنشور: Letter; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group, Specialist Journals Country of Publication: England NLM ID: 8704895 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5551 (Electronic) Linking ISSN: 08876924 NLM ISO Abbreviation: Leukemia Subsets: MEDLINE

مواضيع طبية MeSH: CCAAT-Enhancer-Binding Protein-alpha/*genetics , Leukemia, Myeloid, Acute/*genetics , MicroRNAs/*genetics, Animals ; Mice

المؤلفون: Wojtowicz EE; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Lechman ER; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Hermans KG; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Schoof EM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Wienholds E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Isserlin R; The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., van Veelen PA; Departments of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Broekhuis MJ; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Janssen GM; Departments of Immunohematology and Blood Transfusion, Leiden University Medical Center, 2333 ZA Leiden, the Netherlands., Trotman-Grant A; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Dobson SM; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Krivdova G; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada., Elzinga J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Kennedy J; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Gan OI; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada., Sinha A; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Ignatchenko V; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Kislinger T; Department of Medical Biophysics, University of Toronto, Toronto, ON M5G 1L7, Canada., Dethmers-Ausema B; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Weersing E; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Alemdehy MF; Department of Hematology, Erasmus University Medical Center Cancer Institute, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands., de Looper HW; Department of Hematology, Erasmus University Medical Center Cancer Institute, Wytemaweg 80, 3015 CN Rotterdam, the Netherlands., Bader GD; The Donnelly Centre, University of Toronto, Toronto, ON M5S 3E1, Canada., Ritsema M; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Erkeland SJ; Department of Immunology, Erasmus University Medical Center, Wytemaweg 80, 3015CN Rotterdam, the Netherlands., Bystrykh LV; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands., Dick JE; Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address: jdick@uhnres.utoronto.ca., de Haan G; Laboratory of Ageing Biology and Stem Cells, European Research Institute for the Biology of Ageing, University Medical Centre Groningen, University of Groningen, Antonius Deusinglaan 1, 9700 AV Groningen, the Netherlands. Electronic address: g.de.haan@umcg.nl.

المصدر: Cell stem cell [Cell Stem Cell] 2016 Sep 01; Vol. 19 (3), pp. 383-96. Date of Electronic Publication: 2016 Jul 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101311472 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-9777 (Electronic) Linking ISSN: 18759777 NLM ISO Abbreviation: Cell Stem Cell Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation*, Hematopoietic Stem Cells/*cytology , Hematopoietic Stem Cells/*metabolism , MicroRNAs/*metabolism, ADP-ribosyl Cyclase 1/metabolism ; Animals ; Antigens, CD34/metabolism ; Cell Proliferation ; Cell Self Renewal/genetics ; Gene Regulatory Networks ; Hematopoietic Stem Cell Transplantation ; Humans ; Isotope Labeling ; Male ; Mice, Inbred C57BL ; MicroRNAs/genetics ; Models, Biological ; Multipotent Stem Cells/cytology ; Multipotent Stem Cells/metabolism ; Multipotent Stem Cells/transplantation ; Reproducibility of Results ; Time Factors