-
1
المؤلفون: Alessandra Cirla, Elena Casale, Nilla Avanzi, Marina Ciomei, Viviana Desperati, Helena Posteri, Eduard R. Felder, Gianluca Papeo, Alessia Montagnoli, Arturo Galvani, Marco Guanci, Daniela Borghi, Antonella Isacchi, Daniele Donati, Sonia Rainoldi, Alessandra Scolaro, Paolo Orsini, Federico Riccardi-Sirtori
المصدر: ACS Medicinal Chemistry Letters. 10:534-538
مصطلحات موضوعية: chemistry.chemical_classification, Chemistry, medicine.drug_class, Poly ADP ribose polymerase, Organic Chemistry, Carboxamide, Biochemistry, In vitro, Enzyme, In vivo, Drug Discovery, medicine, NAD+ kinase, IC50, ADME
-
2
المؤلفون: Arturo Galvani, Daniele Donati, Emiliana Corti, Alessandra Cirla, Paolo Orsini, Elena Casale, Francesco Sola, Mikhail Krasavin, Marina Fasolini, Enrico Pesenti, Barbara Forte, Rita Perego, Antonella Isacchi, Alina Busel, Daniela Borghi, Alessia Montagnoli, Fabio Zuccotto, Federico Riccardi-Sirtori, Eduard R. Felder, Helena Posteri, Rosita Lupi, Alexander Viktorovich Khvat, Marina Ciomei, Daniele Pezzetta, Gianluca Papeo, Matteo D'anello, Sonia Rainoldi, Francesco Caprera, Alessandra Scolaro
المصدر: Journal of Medicinal Chemistry. 58:6875-6898
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Poly ADP ribose polymerase, Administration, Oral, Biological Availability, Mice, Nude, Antineoplastic Agents, Triple Negative Breast Neoplasms, Carboxamide, Isoindoles, Poly(ADP-ribose) Polymerase Inhibitors, Pharmacology, Rats, Sprague-Dawley, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Pharmacokinetics, In vivo, Antineoplastic Combined Chemotherapy Protocols, Drug Discovery, Temozolomide, medicine, Animals, Humans, Structure–activity relationship, Cell Proliferation, ADME, Mice, Inbred BALB C, Chemistry, High-Throughput Screening Assays, Dacarbazine, Pancreatic Neoplasms, Microsomes, Liver, Heterografts, Molecular Medicine, Female, Drug Screening Assays, Antitumor, Isoindole, Neoplasm Transplantation, medicine.drug
-
3
المؤلفون: Christian Orrenius, Arturo Galvani, Peter K. Jackson, Paola Magnaghi, Mauro Angiolini, Steven Magnuson, Thomas O'Brien, Liviana Cozzi, Daniele Donati, Nuvoloni Stefano, Alessandra Badari, Elena Casale, Simona Rizzi, Nilla Avanzi, Laura Riceputi, Federico Riccardi Sirtori, Roberto D'Alessio, Yichin Liu, Alessandra Cirla, Silvia Cauteruccio, Beatrice Trucchi, Antonella Isacchi, Paolo Polucci, Daniela Asa, J.A. Bertrand, Malgesini Ms Beatrice
المصدر: Journal of Medicinal Chemistry. 56:437-450
مصطلحات موضوعية: Adenosine Triphosphatases, Poor prognosis, biology, Chemistry, Valosin-containing protein, Allosteric regulation, Cancer therapy, Cell Cycle Proteins, Triazoles, AAA proteins, Structure-Activity Relationship, Allosteric Regulation, Mechanism of action, Biochemistry, Valosin Containing Protein, Neoplasms, Drug Discovery, medicine, biology.protein, Humans, Molecular Medicine, Structure–activity relationship, Protein folding, medicine.symptom
-
4
المؤلفون: Elena Ardini, Dario Ballinari, Eduard R. Felder, Alessandra Cirla, Paolo Polucci, Arturo Galvani, Patrizia Banfi, Antonella Isacchi, Ilaria Motto, Daniele Donati, Cinzia Cristiani, Nilla Avanzi, Andrea Lombardi Borgia, Maria Menichincheri, Matteo D'anello, Marina Ciomei
المصدر: Cancer Research. 78:4785-4785
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, biology, Kinase, Chemistry, Cancer, medicine.disease, Fusion protein, Receptor tyrosine kinase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Medullary carcinoma, In vivo, 030220 oncology & carcinogenesis, biology.protein, medicine, Cancer research, Kinome, Receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1a6daf68179996952cd4c74885a7b924
https://doi.org/10.1158/1538-7445.am2018-4785 -
5
المؤلفون: Nilla Avanzi, Fabio Gasparri, Roberto D'Alessio, Barbara Salom, Graziella Sorrentino, Liviana Cozzi, Antonio Lomolino, Daniele Donati, Michele Caruso, Arturo Galvani, Steven Magnuson, Thomas O'Brien, Alessandra Cirla, Daniela Borghi, Antonella Isacchi, Daniela Asa, Ilaria Motto, Alessandra Badari, Barbara Valsasina, Simona Rizzi, Paola Magnaghi, Maurizio Pasi, Giovanni Cervi, Beatrice Malgesini, Eduard R. Felder, Sonia Troiani
المصدر: Journal of medicinal chemistry. 57(24)
مصطلحات موضوعية: Models, Molecular, Valosin-containing protein, Cell Cycle Proteins, Golgi reassembly, Protein degradation, law.invention, Structure-Activity Relationship, law, Valosin Containing Protein, Drug Discovery, medicine, Humans, Enzyme Inhibitors, Cell Proliferation, Adenosine Triphosphatases, biology, Molecular Structure, Chemistry, Cancer, medicine.disease, HCT116 Cells, Yeast, AAA proteins, Pyrimidines, Biochemistry, Cell cycle control, Recombinant DNA, biology.protein, Molecular Medicine
-
6
المؤلفون: John Mann, Alessandra Cirla, Angela R McHale
المصدر: Tetrahedron. 60:4019-4029
مصطلحات موضوعية: Neocarzinostatin, Chemistry, Stereochemistry, Organic Chemistry, Biological activity, Biochemistry, chemistry.chemical_compound, Glucosamine, Drug Discovery, Calicheamicin, medicine, Cytotoxicity, Neocarzinostatin chromophore, medicine.drug
-
7
المؤلفون: Giulia Canevari, Elena Casale, Nilla Avanzi, Elena Ardini, Arturo Galvani, Nadia Amboldi, Antonella Ermoli, Daniele Donati, Dario Ballinari, Sonia Troiani, Cinzia Cristiani, Alessandra Cirla, Paolo Polucci, Federico Riccardi Sirtori, Marina Ciomei, Eduard R. Felder, Patrizia Banfi, Antonella Isacchi, Ilaria Motto, Maria Menichincheri, Francesco Caprera
المصدر: Cancer Research. 77:2082-2082
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, endocrine system diseases, biology, Chemistry, Kinase, Autophosphorylation, Cancer, medicine.disease, Fusion protein, Receptor tyrosine kinase, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Medullary carcinoma, In vivo, 030220 oncology & carcinogenesis, Cancer research, medicine, Glial cell line-derived neurotrophic factor, biology.protein
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5eeb9bff16133e1758f1ce556997e931
https://doi.org/10.1158/1538-7445.am2017-2082 -
8
المؤلفون: Nilla Avanzi, Sabrina Cribioli, Paola Gnocchi, Jay Bertrand, Danilo Mirizzi, Daniele Casero, Arturo Galvani, Paola Vianello, Maristella Colombo, Eduard R. Felder, Gabriele Fachin, Achille Panzeri, Lucio Ceriani, G. Canevari, Franco Della Vedova, Dario Ballinari, Cinzia Cristiani, Enrico Pesenti, Marcella Nesi, Tiziano Bandiera, Marina Ciomei, Alessandra Cirla, Maria Gabriella Brasca, Antonella Isacchi, Daniele Donati, Ilaria Motto, Simona Bindi, Marina Fasolini, Davide Carenzi
المصدر: Bioorganicmedicinal chemistry. 22(17)
مصطلحات موضوعية: Models, Molecular, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Mice, SCID, Pharmacology, Crystallography, X-Ray, Biochemistry, Substrate Specificity, chemistry.chemical_compound, Mice, Structure-Activity Relationship, Pharmacokinetics, In vivo, Cell Line, Tumor, Drug Discovery, medicine, Transferase, Animals, Humans, Pyrroles, Molecular Biology, Protein Kinase Inhibitors, Pyrrole, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, Chemistry, Organic Chemistry, Neoplasms, Experimental, Protein kinase inhibitor, Janus Kinase 2, Bioavailability, Pyrimidines, Mechanism of action, Molecular Medicine, medicine.symptom, Growth inhibition, Drug Screening Assays, Antitumor
-
9
المؤلفون: Elena Casale, Gianluca Papeo, Alessia Montagnoli, Alessandra Cirla
المصدر: Expert opinion on therapeutic patents. 23(4)
مصطلحات موضوعية: DNA repair, medicine.medical_treatment, Poly ADP ribose polymerase, Cancer therapy, Antineoplastic Agents, Poly(ADP-ribose) Polymerase Inhibitors, Bioinformatics, Poly (ADP-Ribose) Polymerase Inhibitor, Patents as Topic, Structure-Activity Relationship, Neoplasms, Drug Discovery, medicine, Animals, Humans, Database search engine, Molecular Targeted Therapy, Enzyme Inhibitors, Pharmacology, Chemotherapy, Molecular Structure, business.industry, General Medicine, Drug Design, Drug and Narcotic Control, Poly(ADP-ribose) Polymerases, Magic bullet, business, Oncology field, Signal Transduction
-
10
المؤلفون: Marco Tato, Paolo Orsini, Ermes Vanotti, Francesco Fiorentini, Arturo Galvani, Valter Croci, Fabrizio Orzi, Cristina Alli, Jurgen Moll, Maristella Colombo, Roberto D'Alessio, Alberto Bargiotti, Barbara Forte, Enrico Pesenti, Katia Martina, Clara Albanese, Matteo D'anello, Barbara Valsasina, Mario Varasi, Patrizia Giordano, Antonella Isacchi, Alessandra Cirla, Marcellino Tibolla, Antonio Pillan, Antonella Ciavolella, Alessandra Scolaro, Paola Vianello, Fulvia Roletto, Antonella Ermoli, Antonio Molinari, Daniele Volpi, Alessia Montagnoli, Corrado Santocanale, Maria Menichincheri, Francesco Colotta, Dario Ballinari, Marina Caldarelli
المصدر: Journal of medicinal chemistry. 53(20)
مصطلحات موضوعية: Transplantation, Heterologous, Biological Availability, Mice, Nude, Antineoplastic Agents, Cell Cycle Proteins, Protein Serine-Threonine Kinases, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Cell Line, Tumor, Drug Discovery, Structure–activity relationship, Animals, Humans, Pyrroles, ADME, Kinase, Small molecule, In vitro, Transplantation, Pyrimidines, chemistry, Biochemistry, Molecular Medicine, Drug Screening Assays, Antitumor, Lead compound, Neoplasm Transplantation
Find this issue from the American Chemical Society 
PDF full text from Publisher