المؤلفون: Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Nakazawa S; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Harada G; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Lee JK; Foundation Medicine, Cambridge, Massachusetts., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Barrichello A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Vaz VR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gandhi MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gazgalis D; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Feng WW; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Jiang J; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Baldacci S; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Locquet MA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Gottlieb FH; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Chen MF; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Lee E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Haradon D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Smokovich A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Voligny E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Nguyen T; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Goel VK; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Zimmerman Z; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Atwal S; Turning Point Therapeutics, Bristol Myers Squibb Company, San Diego, California., Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston, Massachusetts., Bahcall M; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Heist RS; Massachusetts General Hospital, Boston, Massachusetts., Iqbal S; The Center for the Development of Therapeutics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts.; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, Massachusetts., Gandhi N; Caris Life Sciences, Phoenix, Arizona., Elliott A; Caris Life Sciences, Phoenix, Arizona., Vanderwalde AM; Caris Life Sciences, Phoenix, Arizona., Ma PC; Penn State Cancer Institute, Penn State College of Medicine, Penn State University, Hershey, Pennsylvania., Halmos B; Montefiore Einstein Cancer Center, Bronx, New York., Liu SV; Georgetown University, Washington, DC., Che J; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts., Schrock AB; Foundation Medicine, Cambridge, Massachusetts., Drilon A; Department of Medical Oncology, Memorial Sloan Kettering Cancer Center and Weill Cornell Medical College, New York, New York., Jänne PA; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.

المصدر: Cancer discovery [Cancer Discov] 2024 Aug 02; Vol. 14 (8), pp. 1440-1456.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Proto-Oncogene Proteins c-met*/genetics , Proto-Oncogene Proteins c-met*/antagonists & inhibitors , Lung Neoplasms*/genetics , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology , Protein Kinase Inhibitors*/therapeutic use , Protein Kinase Inhibitors*/pharmacology , Point Mutation*, Humans ; Animals ; Mice ; Cell Line, Tumor

المؤلفون: Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA., Hou K; Bioinformatics Interdepartmental Program, University of California, Los Angeles, 611 Charles E. Young Drive, Los Angeles, CA, USA., Ricciuti B; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Alessi JV; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Li X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA; Department of Biostatistics, University of North Carolina at Chapel Hill, 135 Dauer Drive, Chapel Hill, NC, USA; Department of Genetics, University of North Carolina at Chapel Hill, 120 Mason Farm Road, Chapel Hill, NC, USA., Pecci F; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Dey R; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA., Luo J; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Awad MM; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Gusev A; McGraw/Patterson Center for Population Sciences, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Lin X; Department of Biostatistics, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA., Johnson BE; Lowe Center for Thoracic Oncology and Center for Cancer Genomics, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA, USA., Christiani DC; Department of Environmental Health, Harvard T.H. Chan School of Public Health, 677 Huntington Avenue, Boston, MA, USA; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Massachusetts General Hospital, 55 Fruit Street, Boston, MA, USA. Electronic address: dchris@hsph.harvard.edu.

المصدر: HGG advances [HGG Adv] 2024 Jul 18; Vol. 5 (3), pp. 100320. Date of Electronic Publication: 2024 Jun 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 101772885 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-2477 (Electronic) Linking ISSN: 26662477 NLM ISO Abbreviation: HGG Adv Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/ethnology , Carcinoma, Non-Small-Cell Lung*/pathology , Proto-Oncogene Proteins p21(ras)*/genetics , Lung Neoplasms*/genetics , Lung Neoplasms*/ethnology , Lung Neoplasms*/pathology , Mutation* , Alleles*, Humans ; Male ; Female ; Middle Aged ; Aged ; Prevalence ; Ethnicity/genetics ; Racial Groups/genetics ; Genetic Predisposition to Disease

المؤلفون: Scalera S; Instituto Nazionale Tumori Regina Elena, Rome, Italy., Ricciuti B; Dana Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts, United States., Marinelli D; Sapienza University of Rome, Rome, RM, Italy., Mazzotta M; Policlinico Sant'Andrea, Rome, Italy., Cipriani L; IRCCS Regina Elena National Cancer Institute, Rome, Italy, Rome, RM, Italy., Bon G; IRCCS Regina Elena National Cancer Institute, Rome, Italy, Rome, Italy., Schiavoni G; IRCCS Regina Elena National Cancer Institute, Rome, Italy, Rome, Italy., Terrenato I; Regina Elena Cancer Institute, Rome, Italy., Di Federico A; University of Bologna, Bologna, Italy., Alessi JV; Dana-Farber Cancer Institute, Boston, MA, United States., Fanciulli M; IRCCS Regina Elena National Cancer Institute, Rome, Italy., Ciuffreda L; IRCCS Regina Elena National Cancer Institute, Rome, Italy., De Nicola F; IRCCS Regina Elena National Cancer Institute, Rome, Italy., Goeman F; IRCCS Regina Elena National Cancer Institute, Rome, Italy., Caravagna G; University of Trieste, Trieste, Italy., Santini D; Sapienza University of Rome, Italy., De Maria R; Università Cattolica del Sacro Cuore and Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy., Cappuzzo F; IRCCS Regina Elena National Cancer Institute, Rome, Italy, Rome, Italy., Ciliberto G; IRCCS Regina Elena National Cancer Institute, Rome, Italy., Jamal-Hanjani M; University College London, London, United Kingdom., Awad MM; Dana-Farber Cancer Institute, Boston, Massachusetts, United States., McGranahan N; University College London Cancer Institute, London, -- select state --, United Kingdom., Maugeri-Saccà M; IRCCS Regina Elena National Cancer Institute, Rome, Italy, Rome, Italy.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2024 Jul 09. Date of Electronic Publication: 2024 Jul 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

المؤلفون: Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Alden SL; Johns Hopkins School of Medicine, Baltimore., Smithy JW; Memorial Sloan Kettering Cancer Center, New York., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Wang X; Department of Environmental Health, Harvard T.H. Chan School of Public Health, Harvard University, Boston., Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Gandhi MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Vaz VR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Spurr LF; Pritzker School of Medicine, University of Chicago, Chicago; Department of Radiation and Cellular Oncology, University of Chicago, Chicago., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston., Pfaff KL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston., Li YY; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston; Cancer Program, Broad Institute of MIT and Harvard, Cambridge., Cherniack AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston; Cancer Program, Broad Institute of MIT and Harvard, Cambridge., Nishino M; Department of Radiology, Brigham and Women's Hospital, Boston; Department of Imaging, Dana-Farber Cancer Institute, Boston, USA., Johnson BE; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston. Electronic address: mark_awad@dfci.harvard.edu.

المصدر: Annals of oncology : official journal of the European Society for Medical Oncology [Ann Oncol] 2024 Jun 29. Date of Electronic Publication: 2024 Jun 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 9007735 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1569-8041 (Electronic) Linking ISSN: 09237534 NLM ISO Abbreviation: Ann Oncol Subsets: MEDLINE

المؤلفون: Cheong TC; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA. taekchin.cheong@childrens.harvard.edu., Jang A; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA, 02115, USA., Wang Q; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Leonardi GC; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA.; Department of Biomedical and Biotechnological Sciences, University of Catania, 95123, Catania, Italy., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, 02115, USA., Lehtinen MK; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Harris MH; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA., Chiarle R; Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA. roberto.chiarle@childrens.harvard.edu.; Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, 10126, Italy. roberto.chiarle@childrens.harvard.edu.; Division of Hematopathology, IEO European Institute of Oncology IRCCS, 20141, Milan, Italy. roberto.chiarle@childrens.harvard.edu.

المصدر: Nature communications [Nat Commun] 2024 Jun 14; Vol. 15 (1), pp. 5110. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/genetics , Neoplasms*/drug therapy , Oncogene Proteins, Fusion*/genetics , Oncogene Proteins, Fusion*/metabolism , Protein-Tyrosine Kinases*/genetics , Protein-Tyrosine Kinases*/metabolism , Proto-Oncogene Proteins c-ret*/genetics , Proto-Oncogene Proteins c-ret*/metabolism , Translocation, Genetic*, Humans ; Anaplastic Lymphoma Kinase/genetics ; Anaplastic Lymphoma Kinase/metabolism ; Receptor, trkA/genetics ; Receptor, trkA/metabolism ; Protein Kinase Inhibitors/pharmacology ; Protein Kinase Inhibitors/therapeutic use ; Proto-Oncogene Proteins/genetics ; Proto-Oncogene Proteins/metabolism ; Signal Transduction/genetics ; Cell Line, Tumor

المؤلفون: Chaunzwa TL; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.; Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Qian JM; Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Li Q; AstraZeneca, Cambridge, England and Waltham, Massachusetts., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Nuernberg L; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.; Radiology and Nuclear Medicine, CARIM & GROW, Maastricht University, Maastricht, the Netherlands., Johnson JW; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts., Weiss J; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.; Department of Diagnostic and Interventional Radiology, University Freiburg, Freiburg im Breisgau, Germany., Zhang Z; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts., MacKay J; AstraZeneca, Cambridge, England and Waltham, Massachusetts., Kagiampakis I; AstraZeneca, Cambridge, England and Waltham, Massachusetts., Bikiel D; AstraZeneca, Cambridge, England and Waltham, Massachusetts., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Mak RH; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.; Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts., Jacob E; AstraZeneca, Cambridge, England and Waltham, Massachusetts., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Aerts HJWL; Artificial Intelligence in Medicine Program, Mass General Brigham, Harvard Medical School, Boston, Massachusetts.; Department of Radiation Oncology, Dana Farber Cancer Institute, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.; Radiology and Nuclear Medicine, CARIM & GROW, Maastricht University, Maastricht, the Netherlands.

المصدر: JAMA oncology [JAMA Oncol] 2024 Jun 01; Vol. 10 (6), pp. 773-783.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Medical Association Country of Publication: United States NLM ID: 101652861 Publication Model: Print Cited Medium: Internet ISSN: 2374-2445 (Electronic) Linking ISSN: 23742437 NLM ISO Abbreviation: JAMA Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/therapy , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/therapy , Lung Neoplasms*/pathology , Lung Neoplasms*/mortality , Immunotherapy*/methods , Body Composition*, Humans ; Female ; Male ; Middle Aged ; Aged ; Progression-Free Survival ; Adult

المؤلفون: Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Puchala SR; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Mahadevan NR; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Lin JR; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Chowdhury A; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Li YY; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA., Wang X; Harvard School of Public Health, Boston, MA., Spurr L; Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA., Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Di Federico A; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Venkatraman D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Barrichello AP; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Gandhi M; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Vaz VR; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Pangilinan AJ; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Haradon D; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Lee E; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Gupta H; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Pfaff KL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Welsh EL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Nishino M; Department of Radiology, Brigham and Women's Hospital, Boston, MA., Cherniack AD; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Johnson BE; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA., Weirather JL; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Dryg ID; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Rodig SJ; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Center for Immuno-Oncology, Dana-Farber Cancer Institute, Boston, MA., Sholl LM; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Sorger P; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Santagata S; Department of Pathology, Brigham and Women's Hospital, Boston, MA.; Laboratory of Systems Pharmacology, Department of Systems Biology, Harvard Medical School, Boston, MA.; Ludwig Center at Harvard, Harvard Medical School, Boston, MA., Umeton R; Department of Informatics and Analytics, Dana-Farber Cancer Institute, Boston, MA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA.

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2024 Apr 10; Vol. 42 (11), pp. 1311-1321. Date of Electronic Publication: 2024 Jan 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Immunological*/therapeutic use , Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology, Humans ; Genomics ; Immunophenotyping ; Kelch-Like ECH-Associated Protein 1/metabolism ; NF-E2-Related Factor 2/metabolism ; NF-E2-Related Factor 2/therapeutic use

المؤلفون: Naqash AR; Stephenson Cancer Center, University of Oklahoma Health Sciences Center, Oklahoma City, OK., Floudas CS; Center for Immuno-Oncology, National Cancer Institute, NIH, Bethesda, MD., Aber E; Center for Immuno-Oncology, National Cancer Institute, NIH, Bethesda, MD., Maoz A; Dana Farber Cancer Institute, Boston, MA., Nassar AH; Department of Hematology/Oncology, Yale New Haven Hospital, New Haven, CT., Adib E; Dana Farber Cancer Institute, Boston, MA., Choucair K; Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI., Xiu J; Caris Life Sciences, Phoenix, AZ., Baca Y; Caris Life Sciences, Phoenix, AZ., Ricciuti B; Dana Farber Cancer Institute, Boston, MA., Alessi JV; Dana Farber Cancer Institute, Boston, MA., Awad MM; Dana Farber Cancer Institute, Boston, MA., Kim C; Department of Hematology and Oncology, Georgetown University, Washington, DC., Judd J; Fox Chase Cancer Center, Philadelphia, PA., Raez LE; Memorial Cancer Institute//Florida Atlantic University (FAU), Miami, FL., Lopes G; University of Miami Miller School of Medicine, Miami, FL., Nieva JJ; University of Southern California, Los Angeles, CA., Borghaei H; Fox Chase Cancer Center, Philadelphia, PA., Takebe N; Developmental Therapeutics Clinic, National Cancer Institute, Bethesda, MD., Ma PC; Department of Hematology/ Oncology, Penn State Cancer Institute, Hershey, PA., Halmos B; Medical Oncology, Albert Einstein College of Medicine, NY., Kwiatkowski DJ; Dana Farber Cancer Institute, Boston, MA., Liu SV; Department of Hematology and Oncology, Georgetown University, Washington, DC., Mamdani H; Department of Oncology, Barbara Ann Karmanos Cancer Institute, Wayne State University, Detroit, MI.

المصدر: JCO precision oncology [JCO Precis Oncol] 2024 Feb; Vol. 8, pp. e2300371.

نوع المنشور: Meta-Analysis; Journal Article

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/genetics , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Antineoplastic Agents, Immunological*/therapeutic use, Humans ; Immune Checkpoint Inhibitors/pharmacology ; Immune Checkpoint Inhibitors/therapeutic use ; Progression-Free Survival ; Tumor Microenvironment/genetics ; Tumor Suppressor Protein p53/genetics ; AMP-Activated Protein Kinase Kinases

المؤلفون: Kerepesi C; Institute for Computer Science and Control (SZTAKI), Hungarian Research Network (HUN-REN), Budapest, Hungary., Abushukair HM; Jordan University of Science and Technology, Irbid, Jordan., Ricciuti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA., Nassar AH; Yale School of Medicine, New Haven, CT., Adib E; Brigham and Women's Hospital, Boston, MA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA., Pecci F; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA., Rakaee M; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Fadlullah MZH; Departments of Oncological Sciences and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Tőkés AM; Department of Pathology, Forensic and Insurance Medicine, Semmelweis University, Budapest, Hungary., Rodig SJ; ImmunoProfile, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Boston, MA.; Department of Pathology, Brigham and Women's Hospital, Boston, MA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA., Tan AC; Departments of Oncological Sciences and Biomedical Informatics, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT., Bakacs T; Institute for Computer Science and Control (SZTAKI), Hungarian Research Network (HUN-REN), Budapest, Hungary., Naqash AR; Department of Probability, Alfred Renyi Institute of Mathematics, The Eötvös Loránd Research Network, Budapest, Hungary.; Medical Oncology/TSET Phase 1 Program, Stephenson Cancer Center @The University of Oklahoma, Oklahoma City, OK.

المصدر: JCO precision oncology [JCO Precis Oncol] 2024 Feb; Vol. 8, pp. e2300439.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 101705370 Publication Model: Print Cited Medium: Internet ISSN: 2473-4284 (Electronic) Linking ISSN: 24734284 NLM ISO Abbreviation: JCO Precis Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung*/drug therapy , Carcinoma, Non-Small-Cell Lung*/pathology , Lung Neoplasms*/drug therapy , Lung Neoplasms*/pathology, Humans ; Immune Checkpoint Inhibitors/adverse effects ; CD8-Positive T-Lymphocytes/pathology ; Retrospective Studies ; Tumor Microenvironment

المؤلفون: Elkrief A; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Riccuiti B; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Alessi JV; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Fei T; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Kalvin HL; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Egger JV; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rizvi H; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Thummalapalli R; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Lamberti G; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Plodkowski A; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Hellmann MD; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Kris MG; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Arcila ME; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Baine MK; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Rudin CM; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Lito P; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Ladanyi M; Human Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Pathology and Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Schoenfeld AJ; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Riely GJ; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA., Awad MM; Lowe Center for Thoracic Oncology, Dana-Farber Cancer Institute, Boston, MA, USA., Arbour KC; Department of Medicine, Thoracic Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

المصدر: The oncologist [Oncologist] 2023 Nov 02; Vol. 28 (11), pp. 978-985.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Non-Small-Cell Lung* , Lung Neoplasms*, Humans ; Kelch-Like ECH-Associated Protein 1 ; Platinum ; NF-E2-Related Factor 2 ; Protein Serine-Threonine Kinases