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1
المؤلفون: Jana Flegel, Saad Shaaban, Zhi Jun Jia, Britta Schulte, Yilong Lian, Adrian Krzyzanowski, Malte Metz, Tabea Schneidewind, Fabian Wesseler, Anke Flegel, Alisa Reich, Alexandra Brause, Gang Xue, Minghao Zhang, Lara Dötsch, Isabelle D. Stender, Jan-Erik Hoffmann, Rebecca Scheel, Petra Janning, Fraydoon Rastinejad, Dennis Schade, Carsten Strohmann, Andrey P. Antonchick, Sonja Sievers, Pedro Moura-Alves, Slava Ziegler, Herbert Waldmann
المصدر: Journal of Medicinal Chemistry. 65:16268-16289
مصطلحات موضوعية: Osteoblasts, Receptors, Aryl Hydrocarbon, Drug Discovery, Molecular Medicine, Hedgehog Proteins, Cell Differentiation, Signal Transduction
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2
المؤلفون: Jessica Wagner, Tabea Schneidewind, Alexandra Brause, Herbert Waldmann, Alexandra Friese, Srinivasa Rao Vidadala, Petra Janning, Shobhna Kapoor, Matthias Bischoff, Juhi Sardana, Slava Ziegler, Tim Förster
المصدر: Angewandte Chemie International Edition. 58:13009-13013
مصطلحات موضوعية: Cell, Biology, 010402 general chemistry, medicine.disease_cause, 01 natural sciences, Catalysis, Protein–protein interaction, Ubiquitin-Specific Peptidase 7, Ubiquitin, medicine, Humans, Protein Interaction Maps, DCTP pyrophosphatase 1, Enzyme Inhibitors, Pyrophosphatases, Wnt Signaling Pathway, Tissue homeostasis, 010405 organic chemistry, Wnt signaling pathway, General Medicine, General Chemistry, HCT116 Cells, 0104 chemical sciences, Cell biology, HEK293 Cells, medicine.anatomical_structure, biology.protein, Carcinogenesis, Chemical genetics
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3
المؤلفون: Julian, Wilke, Tatsuro, Kawamura, Hao, Xu, Alexandra, Brause, Alexandra, Friese, Malte, Metz, Dirk, Schepmann, Bernhard, Wünsch, Antonia, Artacho-Cordón, Francisco R, Nieto, Nobumoto, Watanabe, Hiroyuki, Osada, Slava, Ziegler, Herbert, Waldmann
المصدر: Cell chemical biology. 28(6)
مصطلحات موضوعية: Aniline Compounds, Molecular Structure, Proteome, Gene Expression Profiling, Temperature, Heterocyclic Compounds, 2-Ring, Small Molecule Libraries, Mice, Drug Discovery, Tumor Cells, Cultured, Animals, Humans, Receptors, sigma, Female
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9b81aca241df801c6c805c5921000eb8
https://pubmed.ncbi.nlm.nih.gov/33567254 -
4
المؤلفون: Tom Mejuch, Annina Burhop, Alexandra Brause, Slava Ziegler, Tabea Schneidewind, Herbert Waldmann, Sonja Sievers, Axel Pahl
المصدر: Chembiochem
مصطلحات موضوعية: phenotypic profiling, Computational biology, 010402 general chemistry, Iron Chelating Agents, 01 natural sciences, Biochemistry, Small Molecule Libraries, mode of action, antiproliferative, Cell Line, Tumor, medicine, Profiling (information science), Humans, Mode of action, Molecular Biology, Iron Chelator, Dose-Response Relationship, Drug, Molecular Structure, 010405 organic chemistry, Chemistry, Communication, Organic Chemistry, Cell Cycle, Chemical similarity, Small molecule, Communications, 0104 chemical sciences, Hierarchical clustering, Mechanism of action, Biological target, Molecular Medicine, iron chelators, medicine.symptom
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5
المؤلفون: Francisco R. Nieto, Hiroyuki Osada, Nobumoto Watanabe, Herbert Waldmann, Bernhard Wünsch, Hao Xu, Antonia Artacho-Cordón, Alexandra Brause, Malte Metz, Slava Ziegler, Dirk Schepmann, Tatsuro Kawamura, Alexandra Friese, Julian Wilke
المصدر: Cell Chemical Biology. 28:848-854.e5
مصطلحات موضوعية: Pharmacology, Profiling (computer programming), 010405 organic chemistry, Phenotypic screening, Clinical Biochemistry, Context (language use), Computational biology, Biology, Proteomics, 01 natural sciences, Biochemistry, Small molecule, Phenotype, 0104 chemical sciences, chemistry.chemical_compound, Diaminopyrimidine, chemistry, Drug Discovery, Molecular Medicine, Mode of action, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::80233852a94f640e2a0df9f993669921
https://doi.org/10.1016/j.chembiol.2021.01.009 -
6
المؤلفون: Elisabeth Hennes, Herbert Waldmann, Jana Flegel, Ivana Mejdrová, Slava Ziegler, Radim Nencka, Matthias Baumann, Andrei Ursu, Takanari Inoue, Yuta Nihongaki, Lucas Robke, Petra Janning, Hideaki Matsubayashi, Jared Sterneckert, Alexandra Brause, Jan Eickhoff, Lea Kremer, Hans R. Schöler, Susanne Kordes
المصدر: Angewandte Chemie (International Ed. in English)
مصطلحات موضوعية: Cell, Gene Expression, 01 natural sciences, chemistry.chemical_compound, Mice, Osteogenesis, inhibitors, RNA, Small Interfering, Tissue homeostasis, Research Articles, 0303 health sciences, General Medicine, Smoothened Receptor, Hedgehog signaling pathway, Cell biology, 3. Good health, Phosphotransferases (Alcohol Group Acceptor), medicine.anatomical_structure, RNA Interference, Signal transduction, Signal Transduction, Research Article, Cell Survival, Morpholines, Antineoplastic Agents, biological activity, Thiophenes, 010402 general chemistry, Catalysis, Cell Line, Minor Histocompatibility Antigens, 03 medical and health sciences, Structure-Activity Relationship, medicine, Animals, Humans, Hedgehog Proteins, Phosphatidylinositol, Cilia, Hedgehog, 030304 developmental biology, 010405 organic chemistry, General Chemistry, 0104 chemical sciences, chemistry, Purines, Hedgehog Signaling, Smoothened, PI4KB
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7
المؤلفون: Tom Mejuch, Herbert Waldmann, Tabea Schneidewind, Axel Pahl, Alexandra Brause, Slava Ziegler, Annina Burhop, Sonja Sievers
المصدر: ChemBioChem. 21:3160-3160
مصطلحات موضوعية: business.industry, Computer science, Organic Chemistry, Molecular Medicine, Profiling (information science), Pattern recognition, Artificial intelligence, business, Mode of action, Molecular Biology, Biochemistry, Small molecule