المؤلفون: David A Smith, Elena-Raluca Nicoli, Oscar C W Chen, Alexandria Colaco, Stephan Siebel, Stephanie Newman, Dawn Shepherd, Nicole Y Farhat, Andrew E Armitage, Claire Smith, George Seligmann, Mylvaganam Jeyakumar, Alaa Abdul-Sada, Forbes D Porter, Hal Drakesmith, Frances M Platt, Nick Platt

المصدر: Wellcome Open Research, Vol 7 (2023)

مصطلحات موضوعية: Niemann-Pick disease type C, iron, haematology, lysosome, lysosomal storage diseases, eng, Medicine, Science

وصف الملف: electronic resource

Relation: https://wellcomeopenresearch.org/articles/7-267/v2; https://doaj.org/toc/2398-502X

URL الوصول: https://doaj.org/article/88e020958a694dd6970e032b17add1f9

المؤلفون: Oscar C. W. Chen, Alexandria Colaco, Lianne C. Davis, Fedir N. Kiskin, Nicole Y. Farhat, Anneliese O. Speak, David A. Smith, Lauren Morris, Emily Eden, Patricia Tynan, Grant C. Churchill, Antony Galione, Forbes D. Porter, Frances M. Platt

المصدر: JIMD Reports, Vol 56, Iss 1, Pp 46-57 (2020)

مصطلحات موضوعية: calcium (Ca2+), lysosome, lysosome‐related organelle, Niemann‐Pick disease type C, Diseases of the endocrine glands. Clinical endocrinology, RC648-665, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2192-8312

URL الوصول: https://doaj.org/article/0e1a6412d2a14de1a7841b940a26ea33

المؤلفون: Erdinc Sezgin, Fatma Betul Can, Falk Schneider, Mathias P. Clausen, Silvia Galiani, Tess A. Stanly, Dominic Waithe, Alexandria Colaco, Alf Honigmann, Daniel Wüstner, Frances Platt, Christian Eggeling

المصدر: Journal of Lipid Research, Vol 57, Iss 2, Pp 299-309 (2016)

مصطلحات موضوعية: cholesterol/trafficking, fluorescence microscopy, cholesterol/metabolism, lipid rafts, Niemann-Pick type C disease, membranes/model, Biochemistry, QD415-436

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0022227520354651; https://doaj.org/toc/0022-2275

URL الوصول: https://doaj.org/article/7c67c1889c1b4f23aba5ef92dfd792d2

المؤلفون: Frances M. Platt, David Smith, Lauren Morris, Oscar C. W. Chen, Lianne C. Davis, Alexandria Colaco, Emily R. Eden, Forbes D. Porter, Patricia W. Tynan, Fedir N Kiskin, Anneliese O. Speak, Grant C. Churchill, Nicole Y. Farhat, Antony Galione

المصدر: JIMD Reports, Vol 56, Iss 1, Pp 46-57 (2020)
JIMD Reports

مصطلحات موضوعية: Research Report, congenital, hereditary, and neonatal diseases and abnormalities, medicine.medical_specialty, lcsh:QH426-470, Endocrinology, Diabetes and Metabolism, calcium (Ca2+), Biochemistry, Genetics and Molecular Biology (miscellaneous), lcsh:Diseases of the endocrine glands. Clinical endocrinology, Internal medicine, Lysosome, hemic and lymphatic diseases, Organelle, Internal Medicine, medicine, Platelet, Late endosome, Niemann‐Pick disease type C, Niemann–Pick disease, type C, lcsh:RC648-665, Chemistry, Impaired platelet aggregation, nutritional and metabolic diseases, Research Reports, medicine.disease, Sphingolipid, lysosome‐related organelle, lcsh:Genetics, Endocrinology, medicine.anatomical_structure, lysosome, NPC1

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf5d7b8717f1babb1787871291c7958
https://doaj.org/article/0e1a6412d2a14de1a7841b940a26ea33

المؤلفون: Ecem Kaya, Alexandria Colaco, Stefania Zampieri, Chong Y Tan, Antony Galione, Forbes D. Porter, Bruno Bembi, Elias Adriaenssens, Lianne C. Davis, María E. Fernández-Suárez, Patrick Deegan, Frances M. Platt, Andrea Dardis

المصدر: Journal of Inherited Metabolic Disease
Journal of inherited metabolic disease

مصطلحات موضوعية: Adult, congenital, hereditary, and neonatal diseases and abnormalities, 1-Deoxynojirimycin, Tangier disease, ABCA1, Niemann-Pick C1 Protein, Miglustat, Genetics, Humans, Medicine, Substrate reduction therapy, Genetics (clinical), Niemann‐Pick disease type C, Niemann–Pick disease, type C, biology, business.industry, Intracellular Signaling Peptides and Proteins, nutritional and metabolic diseases, Niemann-Pick Disease, Type C, Original Articles, Middle Aged, medicine.disease, substrate reduction therapy, stomatognathic diseases, Treatment Outcome, Disease Pathway, lysosome, Cancer research, biology.protein, Original Article, Human medicine, NPC1, business, Niemann–Pick disease, ATP Binding Cassette Transporter 1, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59620c5b70256d3411ef84c90fab5038
https://doi.org/10.1002/jimd.12191

المؤلفون: Sarah Spiegel, P Hartwig, Thomas Burgoyne, Emily R. Eden, Frances M. Platt, Elena Sanchez-Heras, Alexandria Colaco, Doris Höglinger, Jason Newton, Clare E. Futter

المصدر: Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, Endocytic cycle, General Physics and Astronomy, Endoplasmic Reticulum, 0302 clinical medicine, Cricetinae, hemic and lymphatic diseases, RNA, Small Interfering, lcsh:Science, education.field_of_study, Multidisciplinary, Chemistry, Intracellular Signaling Peptides and Proteins, Niemann-Pick Disease, Type C, Sterol transport, humanities, Mitochondria, 3. Good health, Cell biology, Cholesterol, medicine.anatomical_structure, RNA Interference, lipids (amino acids, peptides, and proteins), congenital, hereditary, and neonatal diseases and abnormalities, Endosome, Science, Population, STARD3, CHO Cells, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Cricetulus, Niemann-Pick C1 Protein, Cell Line, Tumor, Lysosome, medicine, Animals, Humans, education, Endoplasmic reticulum, Membrane Proteins, nutritional and metabolic diseases, Biological Transport, General Chemistry, 030104 developmental biology, lcsh:Q, NPC1, Carrier Proteins, Lysosomes, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05662d3482a67f20f8edcaa8f30f00ca
http://link.springer.com/article/10.1038/s41467-019-12152-2

المؤلفون: Oscar C W Chen, Stephan Siebel, Alexandria Colaco, Elena-Raluca Nicoli, Nick Platt, Dawn Shepherd, Stephanie Newman, Andrew E Armitage, Nicole Y Farhat, George Seligmann, Claire Smith, David A Smith, Alaa Abdul-Sada, Mylvaganam Jeyakumar, Hal Drakesmith, Forbes D Porter, Frances M Platt

المصدر: Wellcome Open Research. 7:267

مصطلحات موضوعية: Medicine (miscellaneous), General Biochemistry, Genetics and Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a936dcbc761347c3a5dd98c98b4bc862
https://doi.org/10.12688/wellcomeopenres.17261.1

المؤلفون: Marja Jäättelä, Alexandria Colaco

المصدر: The Journal of Cell Biology

مصطلحات موضوعية: 0301 basic medicine, Growth factor, medicine.medical_treatment, Cell, Regulator, Endosomes, Cell Biology, Biology, Ragulator complex, Article, Signal pathway, Cell biology, Protein Transport, 03 medical and health sciences, 030104 developmental biology, Cell metabolism, medicine.anatomical_structure, medicine, Signal transduction, Research Articles, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badb7c2c26748ce6bc932719f0a11301
https://doi.org/10.1083/jcb.201710039

المؤلفون: Johan Palmfeldt, Lin Lin, Jinrong Huang, Yonglun Luo, Kenji Maeda, Marja Jäättelä, Fengping Xu, Alexandria Colaco, Knut Kristoffer Bundgaard Clemmensen, Bin Liu, Xin Liu

المصدر: Liu, B, Palmfeldt, J, Lin, L, Colaço, A, Clemmensen, K K B, Huang, J, Xu, F, Liu, X, Maeda, K, Luo, Y & Jäättelä, M 2018, ' STAT3 associates with vacuolar H+-ATPase and regulates cytosolic and lysosomal pH ', Cell Research, vol. 28, no. 10, pp. 996–1012 . https://doi.org/10.1038/s41422-018-0080-0
Cell Research
Liu, B, Palmfeldt, J, Lin, L, Colaco, A, Clemmensen, K K B, Huang, J, Xu, F, Liu, X, Maeda, K, Luo, Y & Jaattela, M 2018, ' STAT3 associates with vacuolar H +-ATPase and regulates cytosolic and lysosomal pH ', Cell Research, vol. 28, no. 10, pp. 996-1012 . https://doi.org/10.1038/s41422-018-0080-0

مصطلحات موضوعية: 0301 basic medicine, STAT3 Transcription Factor, Vacuolar Proton-Translocating ATPases, biology, Activator (genetics), Cell growth, Intracellular pH, Cell Biology, Hydrogen-Ion Concentration, Article, Cell biology, 03 medical and health sciences, Cytosol, 030104 developmental biology, Cell culture, Cancer cell, biology.protein, STAT3, Molecular Biology, Intracellular

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::737cd4e6a435c5c0b002328a64a0dc69
https://pure.au.dk/portal/da/publications/stat3-associates-with-vacuolar-hatpase-and-regulates-cytosolic-and-lysosomal-ph(4a6dd24f-1fc1-4e9a-9919-00b1d3fa919f).html

المؤلفون: Dimitri Moreau, Fabrizio Vacca, Stefania Vossio, Cameron Scott, Alexandria Colaco, Jonathan Paz Montoya, Charles Ferguson, Markus Damme, Marc Moniatte, Robert G. Parton, Frances M. Platt, Jean Gruenberg

المصدر: EMBO Reports

مصطلحات موضوعية: Male, involvement, chemistry.chemical_compound, Mice, 0302 clinical medicine, Piperidines, bodies, thioperamide, intracellular-transport, Molecular Biology of Disease, Membrane & Intracellular Transport, Cells, Cultured, 0303 health sciences, Mice, Inbred BALB C, lysosomal storage disease LSD, Niemann-Pick Disease, Type C, Articles, Cell biology, Cholesterol, Cholesteryl ester, Monoglycerides, lipids (amino acids, peptides, and proteins), Female, Cholesterol storage, Intracellular, medicine.drug, contacts, Endosome, Phospholipid, Endosomes, Endocytosis, Article, lipids, 03 medical and health sciences, trafficking, medicine, Animals, Humans, endosome, phospholipid, 030304 developmental biology, disease, Thioperamide, Fibroblasts, er, chemistry, lipidomics, Lysophospholipids, protein, metabolism, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15fbaa1093ec0395ca835f957bbfd056
https://pubmed.ncbi.nlm.nih.gov/31267706