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1دورية أكاديمية
المؤلفون: David A Eavarone, Linah Al-Alem, Alexey Lugovskoy, Jillian M Prendergast, Rawan I Nazer, Jenna N Stein, Daniel T Dransfield, Jeff Behrens, Bo R Rueda
المصدر: PLoS ONE, Vol 13, Iss 7, p e0201314 (2018)
وصف الملف: electronic resource
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المؤلفون: Lia Luus, Vasileios Askoxylakis, John Wilton, Alexey Lugovskoy, Kenneth J. Olivier, Stephanie Grabow, Jaeyeon Kim, Christine Pien, Geoffrey Kuesters, Suresh K. Tipparaju, Melissa Geddie, Nancy Dumont, Mark E. Hayes, Alexander Koshkaryev, Sarah A Schihl, C. Patrick Reynolds, Rachel Blaydes, Andrew J. Sawyer, James D. Marks, Tad Kornaga, James Suchy, Charles O. Noble, Dmitri B. Kirpotin, Shinji Oyama, Neeraj Kohli, Zhaohua Richard Huang, Walid S. Kamoun, Daryl C. Drummond, Yu Zhou
المصدر: Nature Biomedical Engineering. 3:264-280
مصطلحات موضوعية: Bridged-Ring Compounds, 0301 basic medicine, Drug, media_common.quotation_subject, medicine.medical_treatment, Biomedical Engineering, Medicine (miscellaneous), Antineoplastic Agents, Bioengineering, Docetaxel, Mice, SCID, Pharmacology, Neutropenia, 03 medical and health sciences, 0302 clinical medicine, Mice, Inbred NOD, Cell Line, Tumor, medicine, Animals, Humans, Tissue Distribution, Cell Proliferation, media_common, Liposome, Chemotherapy, business.industry, Receptor, EphA2, Prodrug, medicine.disease, Xenograft Model Antitumor Assays, Tumor Burden, Computer Science Applications, Disease Models, Animal, 030104 developmental biology, Tolerability, Liposomes, Toxicity, Nanoparticles, Taxoids, business, 030217 neurology & neurosurgery, Biotechnology, medicine.drug
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المؤلفون: Ashish Kalra, Jeffrey D. Kearns, Adnan O. Abu-Yousif, Gavin MacBeath, Alexey Lugovskoy, Maria Håkansson, Derek T. Logan, Birgit Schoeberl, Martin Welin, Melissa Geddie, Ulrik B. Nielsen, Neeraj Kohli, Tim Maiwald, Jessica B. Casaletto, Aaron Fulgham, Brian Harms, Shrikanta Chattopadhyay, Stephen Su, Maja Razlog, Antoine Boudot, Kristina Masson, Andreas Raue
المصدر: Proceedings of the National Academy of Sciences. 116:7533-7542
مصطلحات موضوعية: medicine.drug_class, Monoclonal antibody, Mice, chemistry.chemical_compound, Antineoplastic Agents, Immunological, Antigen, Cell Line, Tumor, Antibodies, Bispecific, medicine, Animals, Humans, Binding site, Receptor, Multidisciplinary, biology, Hepatocyte Growth Factor, Chemistry, Epithelial cell adhesion molecule, Neoplasms, Experimental, Proto-Oncogene Proteins c-met, Epithelial Cell Adhesion Molecule, Xenograft Model Antitumor Assays, PNAS Plus, Cancer cell, Cancer research, biology.protein, Hepatocyte growth factor, Antibody, Signal Transduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77fe611f4e29515cf93f14761355c252
https://doi.org/10.1073/pnas.1819085116 -
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المؤلفون: Sergio Iadevaia, Michael D. Curley, Birgit Schoeberl, Adam Camblin, Gege Tan, Alexey Lugovskoy, Chrystal U. Louis, Mari Mino-Kenudson, Vasileios Askoxylakis, Troy Bloom, Victoria Rimkunas, Isabel Yannatos, Daryl C. Drummond
المصدر: Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)مصطلحات موضوعية: Cell signaling, Paclitaxel, Receptor, ErbB-3, Cell Survival, medicine.medical_treatment, lcsh:Medicine, Antineoplastic Agents, Antibodies, Monoclonal, Humanized, Article, Receptor tyrosine kinase, Polyethylene Glycols, Receptor, IGF Type 1, Mice, Growth factor receptor, Ovarian cancer, Cell Line, Tumor, medicine, Animals, Humans, ERBB3, Epidermal growth factor receptor, lcsh:Science, Cell Proliferation, Ovarian Neoplasms, Chemotherapy, Multidisciplinary, biology, business.industry, lcsh:R, Cancer, Drug Synergism, medicine.disease, Xenograft Model Antitumor Assays, Gene Expression Regulation, Neoplastic, Cancer therapeutic resistance, Doxorubicin, Drug Resistance, Neoplasm, biology.protein, Cancer research, lcsh:Q, Female, Cisplatin, business
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المؤلفون: Troy Bloom, Gege Tan, Alexey Lugovskoy, Emily Pace, Victoria Rimkunas, Charlene Minx, Lin Nie, Jason Baum, Sergio Iadevaia, Robert M. Straubinger, J. Marc Pipas, Daryl C. Drummond, Michael D. Curley, Sharlene Adams, Ulrik B. Nielsen, Akos Czibere, Adam Camblin, Birgit Schoeberl, Vasileios Askoxylakis, Chrystal U. Louis
المصدر: Clinical Cancer Research. 24:2873-2885
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Paclitaxel, Receptor, ErbB-3, Receptor expression, Drug Evaluation, Preclinical, Deoxycytidine, Receptor, IGF Type 1, Mice, 03 medical and health sciences, 0302 clinical medicine, Growth factor receptor, Albumins, Cell Line, Tumor, Pancreatic cancer, medicine, Animals, Humans, ERBB3, PI3K/AKT/mTOR pathway, business.industry, Cancer, Receptors, Somatomedin, medicine.disease, Xenograft Model Antitumor Assays, Gemcitabine, Pancreatic Neoplasms, Disease Models, Animal, 030104 developmental biology, Oncology, Caspases, 030220 oncology & carcinogenesis, Cancer cell, Cancer research, business, Signal Transduction, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29efceace7dbca39594d403bd8e3894d
https://doi.org/10.1158/1078-0432.ccr-17-2262 -
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المؤلفون: Alexey Lugovskoy, William J.J. Finlay
المصدر: MAbs
مصطلحات موضوعية: Scrutiny, Process (engineering), Computer science, Emerging technologies, media_common.quotation_subject, Immunology, Big data, Protein Engineering, Epitopes, 03 medical and health sciences, 0302 clinical medicine, Data integrity, Humans, Immunology and Allergy, Computer Simulation, Sophistication, 030304 developmental biology, media_common, 0303 health sciences, business.industry, Antibodies, Monoclonal, Data science, Deconstruction (building), Drug Design, 030220 oncology & carcinogenesis, Transparency (graphic), Perspective, Binding Sites, Antibody, business
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7دورية أكاديمية
المؤلفون: Shamil R Sunyaev, Alexey Lugovskoy, Kenneth Simon, Leonid Gorelik
المصدر: PLoS Genetics, Vol 5, Iss 2, p e1000368 (2009)
وصف الملف: electronic resource
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المؤلفون: Ulrik B. Nielsen, Lihui Xu, Kathy Zhang, Daryl C. Drummond, Tad Kornaga, Alexey Lugovskoy, Neeraj Kohli, Yang Jiao, Melissa Geddie, Dmitri B. Kirpotin, Rachel Rennard
المصدر: mAbs. 7:42-52
مصطلحات موضوعية: Antibody-drug conjugate, Antibodies, Neoplasm, media_common.quotation_subject, Immunology, Yeast display, Mice, Drug Delivery Systems, Antigen, Cell Line, Tumor, Neoplasms, Animals, Humans, Immunology and Allergy, Single-chain variable fragment, Cytotoxic T cell, Internalization, media_common, Cytotoxins, Chemistry, Ligand (biochemistry), Molecular biology, Recombinant Proteins, Amino Acid Substitution, Biophysics, Nanoparticles, Linker, Reports, Single-Chain Antibodies
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المؤلفون: Alexey Lugovskoy, Rachel Rennard, Dmitri B. Kirpotin, Melissa Geddie, Tad Kornaga, Birgit Schoerberl, James D. Marks, Maja Razlog, Lihui Xu, Neeraj Kohli, Yang Jiao, Daryl C. Drummond
المصدر: mAbs, vol 9, iss 1
مصطلحات موضوعية: 0301 basic medicine, Immunoconjugates, Immunoglobulin Variable Region, Nanoparticle, protein A binding, Protein Engineering, 0302 clinical medicine, Drug Delivery Systems, Immunology and Allergy, Nanotechnology, Thermostability, Cancer, Pediatric, biology, antibody engineering, Chemistry, Protein Stability, Receptor, EphA2, Ephrin-A2, Pharmacology and Pharmaceutical Sciences, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Drug delivery, liposome, Public Health and Health Services, manufacturability, Development of treatments and therapeutic interventions, Receptor, Biotechnology, Antibody-drug conjugate, Immunology, Bioengineering, antibody fragment, EphA2, 03 medical and health sciences, Affinity chromatography, Fragment (logic), Report, developability, Single-chain variable fragment, Animals, Humans, stability, Combinatorial chemistry, 030104 developmental biology, biology.protein, Nanoparticles, Immunization, Protein A, Single-Chain Antibodies
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aa91df438843b3da3c3a9876275130f
https://escholarship.org/uc/item/1z81p181 -
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