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1دورية أكاديمية
المؤلفون: Eduardo M. Bruch, Shaolong Zhu, Lisa Szymkowicz, Taylor Blake, Tara Kiss, D. Andrew James, Alexey Rak, Kartik Narayan, Matthew T. Balmer, Roman M. Chicz
المصدر: Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2045-2322
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المؤلفون: Pierre Soule, Amit J. Gupta, Alexey Rak, Semir Jeridi
المصدر: SLAS Discovery. 26:1014-1019
مصطلحات موضوعية: 0301 basic medicine, Drug discovery, Computer science, MAP Kinase Kinase 1, Temperature, Computational biology, behavioral disciplines and activities, Biochemistry, Chemical space, High-Throughput Screening Assays, Analytical Chemistry, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Fragment (logic), 030220 oncology & carcinogenesis, Drug Discovery, Humans, Molecular Medicine, Identification (biology), Protein Kinase Inhibitors, Fluorescent Dyes, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2982ef2c354ea72a6965013ab8a0174
https://doi.org/10.1177/24725552211026267 -
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المؤلفون: Jidong Zhang, Christine Lair, Christine Roubert, Kwame Amaning, María Belén Barrio, Yannick Benedetti, Zhicheng Cui, Zhongliang Xing, Xiaojun Li, Scott G. Franzblau, Nicolas Baurin, Florence Bordon-Pallier, Cathy Cantalloube, Stephanie Sans, Sandra Silve, Isabelle Blanc, Laurent Fraisse, Alexey Rak, Lasse B. Jenner, Gulnara Yusupova, Marat Yusupov, Junjie Zhang, Takushi Kaneko, T.J. Yang, Nader Fotouhi, Eric Nuermberger, Sandeep Tyagi, Fabrice Betoudji, Anna Upton, James C. Sacchettini, Sophie Lagrange
المصدر: Cell. 186:1013-1025.e24
مصطلحات موضوعية: General Biochemistry, Genetics and Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e45831acf54d672d5d43fbfea84a5e9
https://doi.org/10.1016/j.cell.2023.01.043 -
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المؤلفون: Cendrine Lemoine, Anne Sévérac, Sylvain Huille, Alexey Rak, Jacques Dumas, Catherine Prades
المصدر: médecine/sciences. 35:1171-1174
مصطلحات موضوعية: Simultaneity, Computer science, In silico, 010401 analytical chemistry, Decision taking, 02 engineering and technology, General Medicine, 021001 nanoscience & nanotechnology, 0210 nano-technology, 01 natural sciences, Data science, General Biochemistry, Genetics and Molecular Biology, 0104 chemical sciences
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::738ace8a8b6af53c5725c765cb6bd178
https://doi.org/10.1051/medsci/2019232 -
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المؤلفون: Chrystelle Girardet, Magali Mathieu, François Vallée, Jacques Le-Roux, Fangxian Sun, Laurence Fabien, Corinne Terrier, Celine Ginesty, Bruno Filoche-Romme, Florence Gruss-Leleu, Maysoun Shomali, Monsif Bouaboula, Sylvie Beccari, Pascal Desmazeau, Gilles Lebourg, Tsiala Benard, Victor Certal, Pascale Vicat, Andrew Hebert, Carlos Garcia-Echeverria, Laurent Schio, Youssef El-Ahmad, Gary Mccort, Claire Muller, Maurice Brollo, Mikhail Levit, Luc Bertin, Hong Cheng, Véronique Loyau, Valerie Steier, Fabienne Thompson, Audrey Louboutin, Fabienne Pilorge, Alexey Rak, Frank Halley, Patrick Richepin, Christelle Perrault, Pierre-Yves Abecassis, Michel Tabart, Albane Courjaud
المصدر: Journal of Medicinal Chemistry. 63:512-528
مصطلحات موضوعية: 0303 health sciences, biology, Fulvestrant, Chemistry, Estrogen receptor, medicine.disease, 01 natural sciences, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, 03 medical and health sciences, Breast cancer, Hormone receptor, Drug Discovery, biology.protein, medicine, Cancer research, Molecular Medicine, Aromatase, Receptor, Estrogen receptor alpha, Tamoxifen, 030304 developmental biology, medicine.drug
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6دورية
المؤلفون: Mathieu, Magali, Steier, Valérie, Fassy, Florence, Delorme, Cécile, Papin, David, Genet, Bruno, Duffieux, Francis, Bertrand, Thomas, Delarbre, Laure, Le-Borgne, Hélène, Parent, Annick, Didier, Patrick, Marquette, Jean-Pierre, Lowinski, Maryse, Houtmann, Jacques, Lamberton, Annabelle, Debussche, Laurent, Alexey, Rak
المصدر: Small GTPases; December 2022, Vol. 13 Issue: 1 p225-238, 14p
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المؤلفون: Derek J. Wilson, Stephen Li, Salvador F. Ausar, Thomas Bertrand, Jessica Duprez, Roger H. Brookes, Alexey Rak, D. Andrew James, Artur Pedyczak, Shaolong Zhu, Valerie Steier, Anthony Sheung, Michael X Cohen
المصدر: Communications Biology
'Communications Biology ', vol: 3, pages: 427-1-427-12 (2020)
Communications Biology, Vol 3, Iss 1, Pp 1-12 (2020)مصطلحات موضوعية: 0301 basic medicine, Protein vaccines, Protein Conformation, Whooping Cough, Protein subunit, Mutant, Medicine (miscellaneous), chemical and pharmacologic phenomena, CHO Cells, Pertussis toxin, Crystallography, X-Ray, complex mixtures, General Biochemistry, Genetics and Molecular Biology, Article, Bordetella pertussis, 03 medical and health sciences, 0302 clinical medicine, Protein structure, Cricetulus, Cricetinae, Animals, Humans, Mass cytometry, lcsh:QH301-705.5, X-ray crystallography, Pertussis Vaccine, Mass spectrometry, Chemistry, Immunogenicity, Wild type, Deuterium Exchange Measurement, Toxoids, Molecular biology, 030104 developmental biology, lcsh:Biology (General), Pertussis Toxin, NAD+ kinase, General Agricultural and Biological Sciences, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Jacques, Dumas, Anne, Sévérac, Cendrine, Lemoine, Sylvain, Huille, Alexey, Rak, Catherine, Prades
المصدر: Medecine sciences : M/S. 35(12)
مصطلحات موضوعية: Drug Development, Drug Industry, Drug Design, Decision Making, Drug Evaluation, Preclinical, Antibodies, Monoclonal, Humans, Computer Simulation, High-Throughput Screening Assays
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::ae4e65a62e173e2d1f17735e196b6fd2
https://pubmed.ncbi.nlm.nih.gov/31903933 -
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المؤلفون: Claudio Dalvit, Annick Parent, Magali Mathieu, François Vallée, Alexey Rak
المصدر: ChemMedChem. 14(11)
مصطلحات موضوعية: Pharmacology, Magnetic Resonance Spectroscopy, Molecular Structure, 010405 organic chemistry, Chemistry, Ligand, Drug discovery, Organic Chemistry, Large dynamic range, Fragment-based lead discovery, Nuclear magnetic resonance spectroscopy, Ligands, 01 natural sciences, Biochemistry, 0104 chemical sciences, Dissociation constant, 010404 medicinal & biomolecular chemistry, Computational chemistry, Drug Discovery, Molecular Medicine, HSP90 Heat-Shock Proteins, General Pharmacology, Toxicology and Pharmaceutics, Receptor, Binding affinities
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المؤلفون: Alexey Rak, Eric Bacqué, Mireille Kenigsberg, Hélène Goulaouic, Cécile Capdevila, Loreley Calvet, Laurent Schio, Jean Khider, Conception Nemecek, Nathalie Martinet, Eva Albert, Dorothée Semiond, Christine Delaisi, Fabrice Bonche, Jacques Houtmann, Antonio Ugolini, Maryse Lowinski, Sandrine Grapinet, François Vallée, Coumaran Egile, Manfred Roesner
المصدر: Journal of Medicinal Chemistry. 59:7066-7074
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Pharmacology, Crystallography, X-Ray, Mice, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Drug Discovery, medicine, Animals, Humans, Urea, Structure–activity relationship, Benzothiazoles, Protein Kinase Inhibitors, Cell Proliferation, Dose-Response Relationship, Drug, Molecular Structure, CYP3A4, Kinase, Drug discovery, Cell growth, Chemistry, Cancer, Neoplasms, Experimental, Proto-Oncogene Proteins c-met, medicine.disease, Small molecule, 030104 developmental biology, 030220 oncology & carcinogenesis, Molecular Medicine