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1دورية أكاديمية
المؤلفون: Thao Thanh Tran, Carmen D. Mathmann, Marcela Gatica-Andrades, Rachel F. Rollo, Melanie Oelker, Johanna K. Ljungberg, Tam T. K. Nguyen, Alina Zamoshnikova, Lalith K. Kummari, Orry J. K. Wyer, Katharine M. Irvine, Javier Melo-Bolívar, Annette Gross, Darren Brown, Jeffrey Y. W. Mak, David P. Fairlie, Karl A. Hansford, Matthew A. Cooper, Rabina Giri, Veronika Schreiber, Shannon R. Joseph, Fiona Simpson, Timothy C. Barnett, Jörgen Johansson, Wendy Dankers, James Harris, Timothy J. Wells, Ronan Kapetanovic, Matthew J. Sweet, Eleanor A. Latomanski, Hayley J. Newton, Romain J. R. Guérillot, Abderrahman Hachani, Timothy P. Stinear, Sze Ying Ong, Yogeswari Chandran, Elizabeth L. Hartland, Bostjan Kobe, Jennifer L. Stow, A. Elisabeth Sauer-Eriksson, Jakob Begun, Jessica C. Kling, Antje Blumenthal
المصدر: PLoS Pathogens, Vol 18, Iss 1 (2022)
مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607, Biology (General), QH301-705.5
وصف الملف: electronic resource
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المؤلفون: Chien-Hsiung Yu, Alina Zamoshnikova, Thomas E. Schultz, Meg L. Donovan, Jennifer L. Stow, Giorgia Mori, Carmen D Mathmann, Leslie C Domínguez Cadena, Antje Blumenthal
المصدر: Immunology & Cell Biology. 99:1067-1076
مصطلحات موضوعية: Mycobacterium Infections, Tumor Necrosis Factor-alpha, Macrophages, medicine.medical_treatment, Immunology, Golgi Apparatus, Cell Biology, Biology, Golgi apparatus, Mycobacterium bovis, Proinflammatory cytokine, Cell biology, Mice, symbols.namesake, Cytokine, rab GTP-Binding Proteins, medicine, symbols, Animals, Immunology and Allergy, Macrophage, Cytokine secretion, Secretion, Tumor necrosis factor alpha, Rab
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المؤلفون: Avril A. B. Robertson, James A. Fraser, Michael P. Jennings, Jessica L. Chitty, Kate Schroder, James R. Hill, Rebecca C. Coll, Dave Boucher, Christopher J. Day, Alina Zamoshnikova, Nicholas L. Massey
المصدر: Coll, R C, Hill, J R, Day, C J, Zamoshnikova, A, Boucher, D, Massey, N L, Chitty, J L, Fraser, J A, Jennings, M P, Robertson, A A B & Schroder, K 2019, ' MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition ', Nature Chemical Biology, vol. 15, pp. 556–559 . https://doi.org/10.1038/s41589-019-0277-7
مصطلحات موضوعية: 0303 health sciences, integumentary system, Chemistry, 030302 biochemistry & molecular biology, Inflammasome, Cell Biology, Cell biology, 03 medical and health sciences, ATP hydrolysis, NACHT domain, Molecular targets, medicine, Molecular Biology, 030304 developmental biology, medicine.drug
وصف الملف: application/pdf
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المؤلفون: Anne Wilson, Kate Schroder, Steffen Schuster, Christina J. Groß, Fabienne Tacchini-Cottier, Kaiwen W. Chen, Alina Zamoshnikova
المصدر: Immunobiology
مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, MAPK/ERK pathway, Neutrophils, Chemokine CXCL1, Immunology, Biology, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Movement, medicine, Animals, Immunology and Allergy, Leishmania major, Mice, Knockout, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Innate immune system, Macrophages, Intracellular Signaling Peptides and Proteins, NF-kappa B, Pattern recognition receptor, Inflammasome, NF-κB, Cell migration, Dendritic Cells, Hematology, Dendritic cell, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Gene Expression Regulation, chemistry, Organ Specificity, Female, Signal transduction, Signal Transduction, 030215 immunology, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6182cfbfd48c7224b2d94d9273d813e2
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المؤلفون: Rebecca C, Coll, James R, Hill, Christopher J, Day, Alina, Zamoshnikova, Dave, Boucher, Nicholas L, Massey, Jessica L, Chitty, James A, Fraser, Michael P, Jennings, Avril A B, Robertson, Kate, Schroder
المصدر: Nature chemical biology. 15(6)
مصطلحات موضوعية: Sulfonamides, Adenosine Triphosphate, Binding Sites, Indenes, Inflammasomes, Hydrolysis, NLR Family, Pyrin Domain-Containing 3 Protein, Humans, Sulfones, Furans, Heterocyclic Compounds, 4 or More Rings
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المؤلفون: David P. Sester, Parimala R. Vajjhala, Katryn J. Stacey, Simon O. Cridland, Alina Zamoshnikova, Kate Schroder, Sara J. Thygesen
المصدر: Current Protocols in Immunology
مصطلحات موضوعية: 0301 basic medicine, Inflammasomes, Immunology, Cell, Caspase 1, Apoptosis, Cell Separation, Monocytes, Flow cytometry, 03 medical and health sciences, AIM2, 0302 clinical medicine, medicine, Animals, Humans, Caspase, medicine.diagnostic_test, biology, Macrophages, HEK 293 cells, Inflammasome, Flow Cytometry, Cell biology, CARD Signaling Adaptor Proteins, Cytosol, HEK293 Cells, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Single-Cell Analysis, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Katharine M. Irvine, Jasmyn A. Cridland, Vitaliya Sagulenko, Matthew J. Sweet, Alina Zamoshnikova, Katryn J. Stacey, Ayanthi A. Richards, Kate Schroder
المصدر: Immunobiology. 217(12)
مصطلحات موضوعية: Lipopolysaccharides, Lipopolysaccharide, Inflammasomes, medicine.medical_treatment, Immunology, Caspase 1, AIM2, chemistry.chemical_compound, Mice, Downregulation and upregulation, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Immunology and Allergy, Macrophage, Animals, Humans, RNA, Messenger, Promoter Regions, Genetic, Cells, Cultured, integumentary system, Macrophages, Nuclear Proteins, Inflammasome, Hematology, DNA, Cell biology, Up-Regulation, DNA-Binding Proteins, Cytosol, Cytokine, chemistry, Cytokines, Carrier Proteins, medicine.drug, Signal Transduction
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المؤلفون: Kate Schroder, Fabienne Tacchini-Cottier, Flor Vasquez, Alina Zamoshnikova, Ayanthi A. Richards, Christina J. Gross, Steffen Schuster
المصدر: Cytokine. 70:79
مصطلحات موضوعية: Innate immune system, Immunology, Pyroptosis, NOD-like receptor, Inflammasome, Inflammation, Hematology, Biology, Biochemistry, Cell biology, Proinflammatory cytokine, Immune system, medicine, Immunology and Allergy, medicine.symptom, Receptor, Molecular Biology, medicine.drug