المؤلفون: Alisa A. Nevskaya, Rosa Purgatorio, Tatiana N. Borisova, Alexey V. Varlamov, Lada V. Anikina, Arina Yu. Obydennik, Elena Yu. Nevskaya, Mauro Niso, Nicola A. Colabufo, Antonio Carrieri, Marco Catto, Modesto de Candia, Leonid G. Voskressensky, Cosimo D. Altomare

المصدر: Pharmaceuticals, Vol 17, Iss 4, p 539 (2024)

مصطلحات موضوعية: pyrrolo[2,1-a]isoquinolines, Mannich bases, cytotoxicity, P-glycoprotein, inhibition, multidrug resistance reversal, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/17/4/539; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/2d6fcacd9a5e4820a808bb200d14b6c9

المؤلفون: Alisa A. Nevskaya, Lada V. Anikina, Rosa Purgatorio, Marco Catto, Orazio Nicolotti, Modesto de Candia, Leonardo Pisani, Tatiana N. Borisova, Almira R. Miftyakhova, Aleksey V. Varlamov, Elena Yu. Nevskaya, Roman S. Borisov, Leonid G. Voskressensky, Cosimo D. Altomare

المصدر: Molecules, Vol 26, Iss 2, p 359 (2021)

مصطلحات موضوعية: acetylcholinesterase inhibitors, β-amyloid aggregation, anti-Alzheimer’s disease agents, cytotoxicity, pyrrolo[2,1-a]isoquinolines, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/26/2/359; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/18a924e640294c7d9662a70d8de2fee5

المؤلفون: Modesto de Candia, Nunzio Denora, Leonid G. Voskressensky, Mariagrazia Rullo, Rosa Purgatorio, Marco Catto, Antonio Carrieri, Cosimo Altomare, Alisa A. Nevskaya, Leonardo Pisani

المصدر: ChemMedChem. 16:589-598

مصطلحات موضوعية: Models, Molecular, Cell Survival, Serum albumin, Mannich base, 01 natural sciences, Biochemistry, Mannich Bases, Structure-Activity Relationship, chemistry.chemical_compound, Alzheimer Disease, Oral administration, Cell Line, Tumor, Drug Discovery, medicine, Humans, Prodrugs, General Pharmacology, Toxicology and Pharmaceutics, Solubility, Cytotoxicity, Butyrylcholinesterase, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, biology, 010405 organic chemistry, Chemistry, Organic Chemistry, Neurotoxicity, Water, Prodrug, medicine.disease, Combinatorial chemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Neuroprotective Agents, Acetylcholinesterase, biology.protein, Molecular Medicine, Cholinesterase Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475d80d0e8dd664905cd0919676cc366
https://doi.org/10.1002/cmdc.202000583

المؤلفون: Orazio Nicolotti, Roman S. Borisov, Modesto de Candia, Cosimo Altomare, Elena Yu. Nevskaya, Leonardo Pisani, Aleksey V. Varlamov, Lada V. Anikina, Tatiana N. Borisova, Leonid G. Voskressensky, Marco Catto, Rosa Purgatorio, Almira R. Miftyakhova, Alisa A. Nevskaya

المصدر: Molecules
Volume 26
Issue 2
Molecules, Vol 26, Iss 359, p 359 (2021)

مصطلحات موضوعية: Monoamine Oxidase Inhibitors, Stereochemistry, Cell Survival, Pharmaceutical Science, Mixed inhibition, pyrrolo[2,1-a]isoquinolines, 01 natural sciences, Article, Analytical Chemistry, lcsh:QD241-441, 03 medical and health sciences, chemistry.chemical_compound, lcsh:Organic chemistry, β-amyloid aggregation, Alzheimer Disease, Cell Line, Tumor, Neoplasms, Drug Discovery, Moiety, Humans, Physical and Theoretical Chemistry, Isoquinoline, Cytotoxicity, IC50, Monoamine Oxidase, Schiff Bases, 030304 developmental biology, 0303 health sciences, Schiff base, Amyloid beta-Peptides, Cell Death, Organic Chemistry, anti-Alzheimer’s disease agents, Isoquinolines, Acetylcholinesterase, In vitro, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Kinetics, chemistry, Chemistry (miscellaneous), acetylcholinesterase inhibitors, Butyrylcholinesterase, Molecular Medicine, cytotoxicity, Cholinesterase Inhibitors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e532bcc5e1c3fc009c2749f59b3a0f

المؤلفون: Aleksey V. Varlamov, Tatiana N. Borisova, Leonid G. Voskressensky, Almira R. Miftyakhova, Alisa A. Nevskaya, Lada V. Anikina

المصدر: Tetrahedron Letters. 87:153552

مصطلحات موضوعية: Chemistry, Organic Chemistry, Tumor cells, Topoisomerase-I Inhibitor, Biochemistry, Combinatorial chemistry, Cascade reaction, Drug Discovery, medicine, Cytotoxic T cell, Reactivity (chemistry), Cytotoxicity, IC50, Camptothecin, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5a82ec3d980a2071c644d9587f7104af
https://doi.org/10.1016/j.tetlet.2021.153552

المؤلفون: Tatiana N. Borisova, Angelina Boccarelli, Rosa Purgatorio, Nicola Antonio Colabufo, Leonid G. Voskressensky, Mauro Niso, Alisa A. Nevskaya, Modesto de Candia, Maria D. Matveeva, Cosimo Altomare, Saverio Cellamare

المصدر: ChemMedChem. 13:1588-1596

مصطلحات موضوعية: 0301 basic medicine, Stereochemistry, Biochemistry, Madin Darby Canine Kidney Cells, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, 0302 clinical medicine, Cell Line, Tumor, Drug Discovery, Animals, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, General Pharmacology, Toxicology and Pharmaceutics, Isoquinoline, Cytotoxicity, IC50, P-glycoprotein, Pharmacology, biology, Chemistry, Alkaloid, Organic Chemistry, Isoquinolines, Drug Resistance, Multiple, In vitro, Multiple drug resistance, 030104 developmental biology, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer cell, biology.protein, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e11fc0c4c9933a574417fae45168c41b
https://doi.org/10.1002/cmdc.201800177

المؤلفون: Alisa A. Nevskaya, Leonid G. Voskressensky

المصدر: ChemInform. 47

مصطلحات موضوعية: Chemistry, Organic chemistry, General Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::951217aa990593f98df62bc2fa6b14ba
https://doi.org/10.1002/chin.201644219

المؤلفون: Leonid G. Voskressensky, Alisa A. Nevskaya

المصدر: Chemistry of Heterocyclic Compounds. 52:362-363

مصطلحات موضوعية: integumentary system, 010405 organic chemistry, Chemistry, Intramolecular force, Organic Chemistry, 010402 general chemistry, Ring (chemistry), 01 natural sciences, Medicinal chemistry, 0104 chemical sciences

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6a8fcf950459badec1c1f276851c401a
https://doi.org/10.1007/s10593-016-1896-5