المؤلفون: Andrade, CM, Fleckenstein, H, Thomson-Luque, R, Doumbo, S, Lima, NF, Anderson, C, Hibbert, J, Hopp, CS, Tran, TM, Li, SP, Niangaly, M, Cisse, H, Doumtabe, D, Skinner, J, Sturdevant, D, Ricklefs, S, Virtaneva, K, Asghar, M, Homann, MV, Turner, L, Martins, J, Allman, EL, N'Dri, ME, Winkler, V, Llinas, M, Lavazec, C, Martens, C, Farnert, A, Kayentao, K, Ongoiba, A, Lavstsen, T, Osorio, NS, Otto, TD, Recker, M, Traore, B, Crompton, PD, Portugal, S

المصدر: Nature medicine. 26(12):1929-1940

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:145001619

المؤلفون: Andrade, CM, Fleckenstein, H, Thomson-Luque, R, Doumbo, S, Lima, NF, Anderson, C, Hibbert, J, Hopp, CS, Tran, TM, Li, SP, Niangaly, M, Cisse, H, Doumtabe, D, Skinner, J, Sturdevant, D, Ricklefs, S, Virtaneva, K, Asghar, M, Homann, MV, Turner, L, Martins, J, Allman, EL, N'Dri, ME, Winkler, V, Llinas, M, Lavazec, C, Martens, C, Farnert, A, Kayentao, K, Ongoiba, A, Lavstsen, T, Osorio, NS, Otto, TD, Recker, M, Traore, B, Crompton, PD, Portugal, S

المصدر: Nature medicine. 28(10):2216-2216

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:150389650

المؤلفون: Allman Elizabeth S., Rhodes John A., Stanghellini Elena, Valtorta Marco

المصدر: Journal of Causal Inference, Vol 3, Iss 2, Pp 189-205 (2015)

مصطلحات موضوعية: parameter identifiability, discrete bayesian network, hidden variables, Mathematics, QA1-939, Probabilities. Mathematical statistics, QA273-280

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2193-3677; https://doaj.org/toc/2193-3685

URL الوصول: https://doaj.org/article/679237fdea7b4d0abf7866d4f7fcc43d

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المؤلفون: Choudhury FK; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Premkumar V; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Zecha J; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Boyd J; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Gaynor AS; Oncology Cell Therapy, ICC, Oncology R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Guo Z; Biologics Engineering, Cell Therapeutics and Viral Technologies, AstraZeneca, Gaithersburg, Maryland 20878, United States., Martin T; Biologics Engineering, Oncology TTD, ADC, AstraZeneca, Gaithersburg, Maryland 20878, United States., Cimbro R; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge CB2 0AA, United Kingdom., Allman EL; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States., Hess S; Dynamic Omics, Centre for Genomics Research (CGR), Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, Maryland 20878, United States.

المصدر: Journal of proteome research [J Proteome Res] 2024 Aug 02; Vol. 23 (8), pp. 3096-3107. Date of Electronic Publication: 2024 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101128775 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1535-3907 (Electronic) Linking ISSN: 15353893 NLM ISO Abbreviation: J Proteome Res Subsets: MEDLINE

مواضيع طبية MeSH: Flow Cytometry*/methods , Multiomics*, Animals ; Humans ; Cell Separation/methods ; Citric Acid Cycle ; Lab-On-A-Chip Devices ; Microfluidic Analytical Techniques/methods ; Microfluidic Analytical Techniques/instrumentation ; Microfluidics/methods ; Proteomics/methods

المؤلفون: Di Poto C; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 20878, USA., Tian X; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 20878, USA., Mellors S; 908 Devices, Boston, MA, 02210, USA., Rosengren S; Translational Science and Experimental Medicine, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Issop S; Division of Airway Disease, Respiratory Pharmacology Group, NHLI, Imperial College London, London, SW7 2AZ, UK., Bonvini SJ; In Vivo Bioscience, Research and Early Development, Respiratory & Immunology, BioPharmaceuticals R&D, AstraZeneca, London, SW7 2AZ, UK., Hess S; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 20878, USA., Allman EL; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, 20878, USA. Electronic address: erik.allman@astrazeneca.com.

المصدر: Analytica chimica acta [Anal Chim Acta] 2024 Apr 15; Vol. 1298, pp. 342400. Date of Electronic Publication: 2024 Feb 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0370534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4324 (Electronic) Linking ISSN: 00032670 NLM ISO Abbreviation: Anal Chim Acta Subsets: MEDLINE

مواضيع طبية MeSH: Nucleotides* , Microfluidics* , Polyphosphates*, Rats ; Animals ; Humans ; Adenosine Triphosphate/metabolism ; Mass Spectrometry/methods ; Adenosine ; Electrophoresis, Capillary/methods

المؤلفون: Nag A; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Dhindsa RS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA, USA; Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA; Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, Houston, TX 77030, USA., Middleton L; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Jiang X; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Vitsios D; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Wigmore E; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Allman EL; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Reznichenko A; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Carss K; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Smith KR; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Wang Q; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Waltham, MA, USA., Challis B; Translational Science and Experimental Medicine, Research and Early Development, Cardiovascular, Renal and Metabolism (CVRM), BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Paul DS; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Harper AR; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK; Early Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Petrovski S; Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK; Department of Medicine, University of Melbourne, Austin Health, Melbourne, VIC, Australia. Electronic address: slav.petrovski@astrazeneca.com.

المصدر: American journal of human genetics [Am J Hum Genet] 2023 Mar 02; Vol. 110 (3), pp. 487-498. Date of Electronic Publication: 2023 Feb 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0370475 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6605 (Electronic) Linking ISSN: 00029297 NLM ISO Abbreviation: Am J Hum Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study* , Genetic Predisposition to Disease*, Humans ; Biological Specimen Banks ; Biomarkers ; Lipids ; United Kingdom ; Polymorphism, Single Nucleotide

المؤلفون: Dohnalová L; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Molecular Bio Science, Goethe University Frankfurt, and LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany., Lundgren P; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Carty JRE; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Goldstein N; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Wenski SL; Institute for Molecular Bio Science, Goethe University Frankfurt, and LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany., Nanudorn P; Institute for Molecular Bio Science, Goethe University Frankfurt, and LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany., Thiengmag S; Institute for Molecular Bio Science, Goethe University Frankfurt, and LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany., Huang KP; Monell Chemical Senses Center, Philadelphia, PA, USA., Litichevskiy L; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Descamps HC; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Chellappa K; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Glassman A; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kessler S; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kim J; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cox TO; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Dmitrieva-Posocco O; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wong AC; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Allman EL; Department of Biochemistry and Molecular Biology and Department of Veterinary and Biomedical Sciences, the Pennsylvania State University, University Park, PA, USA., Ghosh S; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sharma N; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sengupta K; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Cornes B; The Jackson Laboratory, Bar Harbor, ME, USA., Dean N; Hoss Technology, New York, NY, USA., Churchill GA; The Jackson Laboratory, Bar Harbor, ME, USA., Khurana TS; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Pennsylvania Muscle Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sellmyer MA; Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., FitzGerald GA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Translational Medicine and Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Patterson AD; Department of Biochemistry and Molecular Biology and Department of Veterinary and Biomedical Sciences, the Pennsylvania State University, University Park, PA, USA., Baur JA; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Physiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Alhadeff AL; Monell Chemical Senses Center, Philadelphia, PA, USA.; Department of Neuroscience, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Helfrich EJN; Institute for Molecular Bio Science, Goethe University Frankfurt, and LOEWE Center for Translational Biodiversity Genomics, Frankfurt, Germany., Levy M; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Betley JN; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Department of Biology, University of Pennsylvania, Philadelphia, PA, USA., Thaiss CA; Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. thaiss@pennmedicine.upenn.edu.; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. thaiss@pennmedicine.upenn.edu.; Institute for Obesity, Diabetes and Metabolism, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. thaiss@pennmedicine.upenn.edu.

المصدر: Nature [Nature] 2022 Dec; Vol. 612 (7941), pp. 739-747. Date of Electronic Publication: 2022 Dec 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Dopamine*/metabolism , Motivation* , Brain-Gut Axis*/physiology , Gastrointestinal Microbiome*/physiology , Exercise*/physiology , Exercise*/psychology , Running*/physiology , Running*/psychology, Animals ; Mice ; Brain/cytology ; Brain/metabolism ; Endocannabinoids/antagonists & inhibitors ; Endocannabinoids/metabolism ; Sensory Receptor Cells/metabolism ; Physical Conditioning, Animal/physiology ; Physical Conditioning, Animal/psychology ; Models, Animal ; Humans ; Ventral Striatum/cytology ; Ventral Striatum/metabolism ; Reward ; Individuality

المؤلفون: Petkevicius K; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. kasparas.petkevicius@astrazeneca.com.; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden. kasparas.petkevicius@astrazeneca.com., Palmgren H; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden., Glover MS; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Ahnmark A; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Andréasson AC; Bioscience Cardiovascular, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Madeyski-Bengtson K; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Kawana H; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.; Advanced Research & Development Programs for Medical Innovation (AMED-LEAP), Tokyo, Japan., Allman EL; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Kaper D; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden., Uhrbom M; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Andersson L; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Aasehaug L; Bioscience Cardiovascular, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Forsström J; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Wallin S; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Ahlstedt I; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Leke R; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Karlsson D; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., González-King H; Bioscience Cardiovascular, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Löfgren L; Translational Science and Experimental Medicine, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Nilsson R; Translational Science and Experimental Medicine, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Pellegrini G; Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Kono N; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan., Aoki J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.; Advanced Research & Development Programs for Medical Innovation (AMED-LEAP), Tokyo, Japan., Hess S; Dynamic Omics, Centre for Genomics Research, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gaithersburg, MD, USA., Sienski G; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Pilon M; Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden., Bohlooly-Y M; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Maresca M; Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Peng XR; Bioscience Metabolism, Research and Early Development Cardiovascular, Renal and Metabolism, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden.

المصدر: Nature communications [Nat Commun] 2022 Oct 14; Vol. 13 (1), pp. 6020. Date of Electronic Publication: 2022 Oct 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Non-alcoholic Fatty Liver Disease*/genetics , Non-alcoholic Fatty Liver Disease*/metabolism , Phosphatidylethanolamines*/metabolism, Animals ; Fatty Acids/metabolism ; Fatty Acids, Monounsaturated/metabolism ; Liver/metabolism ; Mice ; Mice, Inbred C57BL ; Mice, Knockout

المؤلفون: Liu Q; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Zhang L; CAS Key Laboratory of Magnetic Resonance in Biological Systems, State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, National Centre for Magnetic Resonance in Wuhan, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences (CAS), Wuhan, 430071, China., Allman EL; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Hubbard TD; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Murray IA; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Hao F; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Tian Y; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Gui W; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Nichols RG; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Smith PB; Huck Institutes of the Life Sciences, University Park, PA, 16802, USA., Anitha M; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Perdew GH; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA., Patterson AD; Center for Molecular Toxicology and Carcinogenesis, Department of Veterinary and Biomedical Sciences, The Pennsylvania State University, University Park, PA, 16802, USA. Electronic address: adp117@psu.edu.

المصدر: Toxicology [Toxicology] 2021 Jun 30; Vol. 458, pp. 152831. Date of Electronic Publication: 2021 Jun 09.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0361055 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3185 (Electronic) Linking ISSN: 0300483X NLM ISO Abbreviation: Toxicology Subsets: MEDLINE

مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*metabolism , Ceramides/*biosynthesis , Lipogenesis/*drug effects , Liver/*drug effects , Liver/*metabolism , Receptors, Aryl Hydrocarbon/*metabolism, Activation, Metabolic/drug effects ; Animals ; Basic Helix-Loop-Helix Transcription Factors/genetics ; Benzofurans/pharmacology ; Ceramides/genetics ; Gene Expression Regulation/drug effects ; Humans ; Lipidomics ; Liver/enzymology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Receptors, Aryl Hydrocarbon/genetics ; Serine C-Palmitoyltransferase/genetics ; Serine C-Palmitoyltransferase/metabolism ; Sphingomyelin Phosphodiesterase/metabolism ; Triglycerides/metabolism