المؤلفون: Madalina Elena Carter-Timofte, Sofie Eg Jørgensen, Mette Ratzer Freytag, Michelle Mølgaard Thomsen, Nanna-Sophie Brinck Andersen, Ali Al-Mousawi, Alon Schneider Hait, Trine H. Mogensen

المصدر: Frontiers in Immunology, Vol 11 (2020)

مصطلحات موضوعية: SARS-coronavirus 2, host immune defenses, immunopathology, innate immunity, primary immunodeficiency, whole exome sequencing, Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fimmu.2020.01606/full; https://doaj.org/toc/1664-3224

URL الوصول: https://doaj.org/article/11aae9949eee4119a697730a8e31c421

المؤلفون: Ali Al-Mousawi, Marie Helleberg, Jakob T Bay, Alon Schneider Hait, David Olagnier, Mette Ratzer Freytag, Sofie E. Jørgensen, Trine H. Mogensen, Michelle M. Thomsen

المصدر: Freytag, M R, Jørgensen, S E, Thomsen, M M, Al-Mousawi, A, Hait, A S, Olagnier, D, Bay, J T, Helleberg, M & Mogensen, T H 2022, ' Postpartum Disseminated Herpes Simplex Virus Type 1 Infection With Hemophagocytic Lymphohistiocytosis and Fulminant Neonatal Herpes Infection ', The Journal of Infectious Diseases, vol. 225, no. 1, pp. 157-162 . https://doi.org/10.1093/infdis/jiab290

مصطلحات موضوعية: viruses, Fulminant, Context (language use), Herpesvirus 1, Human, medicine.disease_cause, Antiviral Agents, Communicable Diseases, Lymphohistiocytosis, Hemophagocytic, Young Adult, Interferon, Exome Sequencing, medicine, Humans, Immunology and Allergy, Pregnancy Complications, Infectious, Exome sequencing, Hemophagocytic lymphohistiocytosis, Mutation, Innate immune system, business.industry, Postpartum Period, Herpes Simplex, medicine.disease, Immunity, Innate, Infectious Disease Transmission, Vertical, Infectious Diseases, Herpes simplex virus, Immunology, Cytokines, Female, Interferons, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c8bd0d514c2402a8293f6d2cb8d8480
https://doi.org/10.1093/infdis/jiab290

المؤلفون: Christian K. Holm, Anne L. Thielke, Rasmus Ottosen, Thomas B. Poulsen, Jinrong Huang, Alice Knudsen, Lydia Bartsch, Siddharth Balachandran, Marie B. Iversen, Camilla G. Nielsen, Victoria H. Gilchrist, Trine H. Mogensen, Huy-Dung Hoang, Alon Schneider Hait, Sofie E. Jørgensen, Line S. Reinert, Suraj Peri, Jan Rehwinkel, Michael Lappe, Charlotte Möller, Michelle M. Thomsen, John Hiscott, Demi van der Horst, Esben B. Svenningsen, Anne Louise Hansen, Yonglun Luo, Jacob Thyrsted, Manja Idorn, Antonio Alcami, Ensieh Farahani, Julia Blay-Cadanet, Martin R. Jakobsen, Bruno Hernáez, Mirjam Schilling, David Olagnier, Søren R. Paludan, Angela Herengt, Tommy Alain

المساهمون: Ester M Og Konrad Kristian Sigurdssons Dyreværnsfond, Beckett Fonden, Hørslev Fonden, Medical Research Council (UK), Lundbeck Foundation, Independent Research Fund Denmark, Carlsberg Foundation, European Research Council, European Commission, Associazione Italiana per la Ricerca sul Cancro, Olagnier, David, Idorn, Manja, Reinert, Line, Jakobsen, Martin, Svenningsen, Esben B., Luo, Yonglun, Rehwinkel, Jan, Alcamí, Antonio, Paludan, Søren R., Holm, Christian, Government of the United Kingdom, Olagnier, David [0000-0001-6912-0674], Idorn, Manja [0000-0002-6769-9165], Reinert, Line [0000-0002-8317-0886], Jakobsen, Martin [0000-0001-8847-9201], Svenningsen, Esben B. [0000-0001-5118-6499], Luo, Yonglun [0000-0002-0007-7759], Rehwinkel, Jan [0000-0003-3841-835X], Alcamí, Antonio [0000-0002-3333-6016], Paludan, Søren R. [0000-0001-9180-4060], Holm, Christian [0000-0002-2655-3362]

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Olagnier, D, Farahani, E, Thyrsted, J, Blay-Cadanet, J, Herengt, A, Idorn, M, Hait, A, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M, Reinert, L S, Lappe, M, Hoang, H-D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, no. 1, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Olagnier, D P C, Farahani, E, Jensen, J T, Blay Cadanet, J, Herengt, A A P V, Idorn, M, Schneider Hait, A I, Hernaez, B, Knudsen, A, Iversen, M B, Schilling, M, Jørgensen, S E, Thomsen, M M, Reinert, L S, Lappe, M, Hoang, H D, Gilchrist, V H, Hansen, A L, Ottosen, R, Nielsen, C G, Møller, C, van der Horst, D, Peri, S, Balachandran, S, Huang, J, Jakobsen, M, Svenningsen, E B, Poulsen, T B, Bartsch, L, Thielke, A L, Luo, Y, Alain, T, Rehwinkel, J, Alcamí, A, Hiscott, J, Mogensen, T H, Paludan, S R & Holm, C K 2020, ' SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate ', Nature Communications, vol. 11, 4938 . https://doi.org/10.1038/s41467-020-18764-3
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature Communications

مصطلحات موضوعية: 0301 basic medicine, DEFENSE, viruses, Science, Immunology, General Physics and Astronomy, SARS-COV-2, SOFTWARE, Microbiology, Article, General Biochemistry, Genetics and Molecular Biology, Virus, NRF2, ACTIVATION, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Interferon, medicine, lcsh:Science, GeneralLiterature_REFERENCE(e.g.,dictionaries,encyclopedias,glossaries), Hardware_REGISTER-TRANSFER-LEVELIMPLEMENTATION, Multidisciplinary, Dimethyl fumarate, Chemistry, SARS-CoV-2, INDUCTION, General Chemistry, respiratory system, Virology, 3. Good health, 030104 developmental biology, INTERFERON REGULATORY FACTOR-3, Viral replication, Cell culture, lcsh:Q, Vaccinia, Signal transduction, 030217 neurology & neurosurgery, Interferon type I, medicine.drug, Hardware_LOGICDESIGN

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c770a0f99e983608245ee2ef5c88b25
https://doaj.org/article/7eb1ed3741cc4fbfa366937b0037cc35

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المؤلفون: Trine H. Mogensen, Kristian Alsbjerg Skipper, Martin K. Thomsen, Ensieh Farahani, Sofie E. Jørgensen, Alon Schneider Hait, Jacob Giehm Mikkelsen, Lise Kay, Søren R. Paludan, Mariane H. Schleimann, Johanna Heinz, Michelle M. Thomsen, Yujia Cai, Nanna-Sophie Brinck Andersen, Simon Muller Larsen

المصدر: Brinck Andersen, N S, Jørgensen, S E, Skipper, K A, Larsen, S M, Heinz, J, Thomsen, M M, Farahani, E, Cai, Y, Hait, A S, Kay, L, Giehm Mikkelsen, J, Høgsbjerg Schleimann, M, Thomsen, M K, Paludan, S R & Mogensen, T H 2021, ' Essential role of autophagy in restricting poliovirus infection revealed by identification of an ATG7 defect in a poliomyelitis patient ', Autophagy, vol. 17, no. 9, pp. 2449-2464 . https://doi.org/10.1080/15548627.2020.1831800
Autophagy

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, autophagy, PATHOGENESIS, Disease, Biology, IMMUNITY, medicine.disease_cause, Autophagy-Related Protein 7, DENDRITIC CELLS, whole exome sequencing, LESSONS, PROTECTS, 03 medical and health sciences, Interferon, medicine, Autophagy, Humans, Molecular Biology, innate immunity, neuronal-like cells, MUTATION, Neurons, Innate immune system, 030102 biochemistry & molecular biology, poliovirus, RECEPTOR, Effector, Poliovirus, INDUCTION, Cell Biology, 3. Good health, 030104 developmental biology, host genetics, MACROAUTOPHAGY, Immunology, Interferon Type I, ATG7, Viral load, PATHOGENICITY, medicine.drug, Research Paper, Poliomyelitis, poliomyelitis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52af82cd582d877d97ab3fc590191c99
https://pure.au.dk/portal/da/publications/essential-role-of-autophagy-in-restricting-poliovirus-infection-revealed-by-identification-of-an-atg7-defect-in-a-poliomyelitis-patient(a498e2fb-f7a9-4eb3-8c46-a0a229da79ab).html

المؤلفون: Mette Christiansen, Maibritt Mardahl, Alon Schneider Hait, Christian Brandt, Simon Muller Larsen, Michelle M. Thomsen, Trine H. Mogensen, Toke S. Barfod, Marie Helleberg

المصدر: Hait, A S, Thomsen, M M, Larsen, S M, Helleberg, M, Mardahl, M, Barfod, T S, Christiansen, M, Brandt, C & Mogensen, T H 2021, ' Whole-Exome Sequencing of Patients With Recurrent HSV-2 Lymphocytic Mollaret Meningitis ', The Journal of Infectious Diseases, vol. 223, no. 10, pp. 1776-1786 . https://doi.org/10.1093/infdis/jiaa589

مصطلحات موضوعية: 0301 basic medicine, autophagy, recurrent HSV-2 meningitis, Herpesvirus 2, Human, Disease, medicine.disease_cause, Lymphocytic choriomeningitis, 03 medical and health sciences, 0302 clinical medicine, Immune system, Immunity, Interferon, Recurrence, Exome Sequencing, medicine, Immunology and Allergy, Humans, Meningitis, Lymphocytes, whole-exome sequencing, Exome sequencing, business.industry, Herpes Simplex, interferon, medicine.disease, 3. Good health, 030104 developmental biology, Infectious Diseases, Herpes simplex virus, Immunology, Interferons, business, 030217 neurology & neurosurgery, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd312c0142897abf404d84833320541f
https://pure.au.dk/portal/da/publications/wholeexome-sequencing-of-patients-with-recurrent-hsv2-lymphocytic-mollaret-meningitis(bf70d9ec-a3f4-450f-aad6-1dd930710482).html

المؤلفون: Maibritt Mardahl, Trine H. Mogensen, Mette Holm, Alon Schneider, Jens Erik Veirum, Mette Christiansen, Thomas Kielsgaard Kristensen, Sofie E. Jørgensen, Klas Raaschou-Jensen, Kristian Assing, Isik Somuncu Johansen

المصدر: Mardahl, M, Jørgensen, S E, Schneider, A, Raaschou-Jensen, K, Holm, M, Veirum, J, Kristensen, T K, Johansen, I S, Christiansen, M, Assing, K & Mogensen, T H 2019, ' Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC ', British Journal of Haematology, vol. 186, no. 3, pp. 471-476 . https://doi.org/10.1111/bjh.15947
University of Southern Denmark
Mardahl, M, Jørgensen, S E, Schneider, A, Kræsten Raaschou Jensen, K, Holm, M, Veirum, J E, Kielsgaard Kristensen, T, Johansen, I S, Christiansen, M, Assing, K & Mogensen, T 2019, ' Impaired immune responses to herpesviruses and microbial ligands in patients with MonoMAC ', 2019 Focused Meeting of the European Society for Immunodeficiencies (ESID 2019), Bruxelles, Belgium, 18/09/2019-21/09/2019 .

مصطلحات موضوعية: Adult, Male, herpesviruses, Myeloid, mycobacteria, Ligands, Germline, Young Adult, 03 medical and health sciences, 0302 clinical medicine, GATA2, medicine, Humans, Child, haematological malignancy, Transcription factor, Herpesviridae, MonoMAC, Immunodeficiency, Cytopenia, business.industry, Immunologic Deficiency Syndromes, Hematology, medicine.disease, GATA2 Transcription Factor, medicine.anatomical_structure, innate immune responses, 030220 oncology & carcinogenesis, Immunology, Primary immunodeficiency, Female, business, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dcdfa9bbe7244286e25ef351c1d7bcc
https://doi.org/10.1111/bjh.15947

المؤلفون: Søren R. Paludan, Alon Schneider Hait, Sathya Darmalinggam, Mette Christiansen, Simon Muller Larsen, Jørgen Kjems, Darshana D. Kadekar, Kristina Eriksson, Serge Mostowy, Liviu Ionut Moldovan, Nanna-Sophie Brinck Andersen, Vanessa Sancho-Shimizu, Trine H. Mogensen, Lasse Sommer Kristensen, Isobel Parkes, David Olagnier, Marie Helleberg, Demi van der Horst, Michelle M. Thomsen, Mette Ratzer Freytag, Kristian Alsbjerg Skipper, Stine H. Rahbek, Jacob Giehm Mikkelsen, Christian Brandt, Chiranjeevi Bodda, Fanghui Ren

المصدر: Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Brinck Andersen, N-S, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2020, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science Immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/sciimmunol.abc2691
Hait, A S, Olagnier, D, Sancho-Shimizu, V, Skipper, K A, Helleberg, M, Larsen, S M, Bodda, C, Moldovan, L I, Ren, F, Andersen, N S B, Thomsen, M M, Freytag, M R, Darmalinggam, S, Parkes, I, Kadekar, D D, Rahbek, S H, van der Horst, D, Kristensen, L S, Eriksson, K, Kjems, J, Mostowy, S, Christiansen, M, Mikkelsen, J G, Brandt, C T, Paludan, S R & Mogensen, T H 2021, ' Defects in LC3B2 and ATG4A underlie HSV2 meningitis and reveal a critical role for autophagy in antiviral defense in humans ', Science immunology, vol. 5, no. 54, eabc2691 . https://doi.org/10.1126/SCIIMMUNOL.ABC2691
Science Immunology

مصطلحات موضوعية: 0301 basic medicine, Programmed cell death, Mutation, Immunology, Autophagy, General Medicine, Gene delivery, Biology, medicine.disease, medicine.disease_cause, Virus, 3. Good health, Cold sore, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Viral replication, 030220 oncology & carcinogenesis, Cancer research, medicine, ATG4A

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76e2d27ad827935f3a3c72318f2fa311
https://pure.au.dk/portal/da/publications/defects-in-lc3b2-and-atg4a-underlie-hsv2-meningitis-and-reveal-a-critical-role-for-autophagy-in-antiviral-defense-in-humans(660e28c6-e88f-4155-8813-69748e66d63d).html

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المؤلفون: Jinrong Huang, Demi van der Horst, Lydia Bartsch, Marie B. Iversen, Line S. Reinert, Camilla Gunderstofte, Esben B. Svenningsen, Anne Louise Hansen, Anne L. Thielke, Tommy Alain, Bruno Hernáez, Huy-Dung Hoang, John Hiscott, Thomas B. Poulsen, Charlotte Möller, Julia Blay Cadanet, Sofie E. Jørgensen, Christian K. Holm, Michael Lappe, Alon Schneider Hait, Jan Rehwinkel, Yonglun Luo, Jacob Thyrsted, Martin R. Jakobsen, Rasmus Ottosen, Michelle M. Thomsen, Søren R. Paludan, Manja Idorn, Antonio Alcami, Suraj Peri, Ensieh Farahani, Angela Herengt, Mirjam Schilling, David Olagnier, Trine H. Mogensen, Alice Knudsen, Siddharth Balachandran, Victoria H. Gilchrist

المساهمون: Ester M Og Konrad Kristian Sigurdssons Dyreværnsfond, Beckett Fonden, Hørslev Fonden, Medical Research Council (UK), Lundbeck Foundation, Independent Research Fund Denmark, Carlsberg Foundation, European Research Council, European Commission, Associazione Italiana per la Ricerca sul Cancro, Poulsen, Thomas B. [0000-0002-0763-9996], Poulsen, Thomas B.

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname

مصطلحات موضوعية: 0303 health sciences, Coronavirus disease 2019 (COVID-19), European research, viruses, 4-octyl-itaconate, COVID-19, Dimethyl fumarate, 3. Good health, 03 medical and health sciences, 0302 clinical medicine, NRF2 anti-oxidant gene expression pathway, SARS-CoV2, European commission, Theology, 030217 neurology & neurosurgery, Nrf2 signaling, Independent research, 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78d0c8a4ddfb8c2f90f5fcc79fbd2a4
https://doi.org/10.1101/2020.07.16.206458