المؤلفون: Zaraei SO; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al-Ach NN; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Anbar HS; Department of Clinical Pharmacy and Pharmacotherapeutics, Dubai Pharmacy College for Girls, Dubai, 19099, United Arab Emirates., El-Gamal R; Department of Medical Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt., Tarazi H; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Tokatly RT; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Kalla RR; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Munther MA; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Wahba MM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Alshihabi AM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Shehata MK; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Sbenati RM; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., Shahin AI; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates., El-Awady R; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Pharmacy Practice and Pharmacotherapeutics, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., Al-Tel TH; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates., El-Gamal MI; Sharjah Institute for Medical Research, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, College of Pharmacy, University of Sharjah, Sharjah, 27272, United Arab Emirates; Department of Medicinal Chemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt. Electronic address: malgamal@sharjah.ac.ae.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2022 Aug 05; Vol. 238, pp. 114434. Date of Electronic Publication: 2022 May 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Hydroxyquinolines*/pharmacology , Quinolines*/chemistry, Caco-2 Cells ; Cell Line, Tumor ; Cell Proliferation ; Dose-Response Relationship, Drug ; Drug Design ; Drug Screening Assays, Antitumor ; Humans ; Molecular Structure ; Protein Kinase Inhibitors/chemistry ; Proto-Oncogene Proteins c-raf/pharmacology ; Sorafenib/pharmacology ; Structure-Activity Relationship