المؤلفون: Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. laura.pallett@ucl.ac.uk., Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Diniz M; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Maini AA; Division of Medicine, University College London, London, UK., Schwabenland M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany., Gasull AD; Institute of Neuropathology, University of Freiburg, Freiburg, Germany., Davies J; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Skelton JK; Department of Medicine, Imperial College London, London, UK., Thomas N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Gill US; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Stegmann KA; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Burton AR; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Stephenson E; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Reynolds G; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Whelan M; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Sanchez J; School of Immunology and Microbial Sciences, Kings College London, London, UK., de Maeyer R; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Thakker C; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Suveizdyte K; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Uddin I; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Ortega-Prieto AM; Department of Medicine, Imperial College London, London, UK., Grant C; Division of Surgery, University College London, London, UK., Froghi F; Division of Surgery, University College London, London, UK., Fusai G; Division of Surgery, University College London, London, UK., Lens S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.; Liver Unit, Hospital Clinic, IDIBAPS and CIBEREHD, University of Barcelona, Barcelona, Spain., Pérez-Del-Pulgar S; Liver Unit, Hospital Clinic, IDIBAPS and CIBEREHD, University of Barcelona, Barcelona, Spain., Al-Akkad W; Institute for Liver & Digestive Health, University College London, London, UK., Mazza G; Institute for Liver & Digestive Health, University College London, London, UK., Noursadeghi M; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Akbar A; Division of Medicine, University College London, London, UK., Kennedy PTF; Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Davidson BR; Division of Surgery, University College London, London, UK., Prinz M; Institute of Neuropathology, University of Freiburg, Freiburg, Germany.; Center for Basics in NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Chain BM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.; Department of Computer Science, University College London, London, UK., Haniffa M; Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Gilroy DW; Division of Medicine, University College London, London, UK., Dorner M; Department of Medicine, Imperial College London, London, UK., Bengsch B; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany.; Faculty of Medicine, Clinic for Internal Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Disease, University Medical Center Freiburg, Freiburg, Germany., Schurich A; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK.; School of Immunology and Microbial Sciences, Kings College London, London, UK., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.

المصدر: Nature [Nature] 2023 Feb; Vol. 614 (7947), pp. 334-342. Date of Electronic Publication: 2023 Jan 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: CD8-Positive T-Lymphocytes*/cytology , CD8-Positive T-Lymphocytes*/drug effects , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Lipopolysaccharide Receptors*/metabolism , Lipopolysaccharides*/immunology , Lipopolysaccharides*/pharmacology , Myeloid Cells*/immunology , Myeloid Cells*/metabolism , Immune Tolerance*/drug effects , Immune Tolerance*/immunology , Liver*/drug effects , Liver*/immunology , Liver*/pathology , Liver*/virology, Humans ; Neoplasms/immunology ; Neoplasms/pathology ; Receptors, Antigen, T-Cell/immunology ; Receptors, Antigen, T-Cell/metabolism ; Interleukin-2/biosynthesis ; Interleukin-2/immunology ; Chemotaxis, Leukocyte ; Bacteria/immunology ; Intestines/immunology ; Intestines/microbiology

المؤلفون: Reynolds CJ; Department of Infectious Disease, Imperial College London, London, UK., Pade C; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Gibbons JM; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Otter AD; UK Health Security Agency, Porton Down, UK., Lin KM; Department of Infectious Disease, Imperial College London, London, UK., Muñoz Sandoval D; Department of Infectious Disease, Imperial College London, London, UK., Pieper FP; Department of Infectious Disease, Imperial College London, London, UK., Butler DK; Department of Infectious Disease, Imperial College London, London, UK., Liu S; Department of Infectious Disease, Imperial College London, London, UK., Joy G; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Forooghi N; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Treibel TA; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., Manisty C; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., Moon JC; St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., Semper A; UK Health Security Agency, Porton Down, UK., Brooks T; UK Health Security Agency, Porton Down, UK., McKnight Á; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Altmann DM; Department of Immunology and Inflammation, Imperial College London, London, UK., Boyton RJ; Department of Infectious Disease, Imperial College London, London, UK.; Lung Division, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Abbass H, Abiodun A, Alfarih M, Alldis Z, Altmann DM, Amin OE, Andiapen M, Artico J, Augusto JB, Baca GL, Bailey SNL, Bhuva AN, Boulter A, Bowles R, Boyton RJ, Bracken OV, O'Brien B, Brooks T, Bullock N, Butler DK, Captur G, Carr O, Champion N, Chan C, Chandran A, Coleman T, Couto de Sousa J, Couto-Parada X, Cross E, Cutino-Moguel T, D'Arcangelo S, Davies RH, Douglas B, Di Genova C, Dieobi-Anene K, Diniz MO, Ellis A, Feehan K, Finlay M, Fontana M, Forooghi N, Francis S, Gibbons JM, Gillespie D, Gilroy D, Hamblin M, Harker G, Hemingway G, Hewson J, Heywood W, Hickling LM, Hicks B, Hingorani AD, Howes L, Itua I, Jardim V, Lee WJ, Jensen M, Jones J, Jones M, Joy G, Kapil V, Kelly C, Kurdi H, Lambourne J, Lin KM, Liu S, Lloyd A, Louth S, Maini MK, Mandadapu V, Manisty C, McKnight Á, Menacho K, Mfuko C, Mills K, Millward S, Mitchelmore O, Moon C, Moon J, Muñoz Sandoval D, Murray SM, Noursadeghi M, Otter A, Pade C, Palma S, Parker R, Patel K, Pawarova M, Petersen SE, Piniera B, Pieper FP, Rannigan L, Rapala A, Reynolds CJ, Richards A, Robathan M, Rosenheim J, Rowe C, Royds M, Sackville West J, Sambile G, Schmidt NM, Selman H, Semper A, Seraphim A, Simion M, Smit A, Sugimoto M, Swadling L, Taylor S, Temperton N, Thomas S, Thornton GD, Treibel TA, Tucker A, Varghese A, Veerapen J, Vijayakumar M, Warner T, Welch S, White H, Wodehouse T, Wynne L, Zahedi D, Chain B, Moon JC

مؤلفون مشاركون: COVIDsortium Investigators§, COVIDsortium Immune Correlates Network§

المصدر: Science (New York, N.Y.) [Science] 2022 Jul 15; Vol. 377 (6603), pp. eabq1841. Date of Electronic Publication: 2022 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: B-Lymphocytes*/immunology , BNT162 Vaccine*/immunology , BNT162 Vaccine*/therapeutic use , COVID-19*/immunology , COVID-19*/prevention & control , Immunization, Secondary* , SARS-CoV-2*/genetics , SARS-CoV-2*/immunology , T-Lymphocytes*/immunology, Animals ; Antibodies, Neutralizing/immunology ; Antibodies, Viral/immunology ; Cross Reactions ; Humans ; Mice ; Spike Glycoprotein, Coronavirus/genetics ; Spike Glycoprotein, Coronavirus/immunology

SCR Organism: SARS-CoV-2 variants

المؤلفون: Wiggins BG; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Pallett LJ; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, UK., Li X; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Department of Infectious Diseases and Guangdong Provincial Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou, China., Davies SP; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Amin OE; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, UK., Gill US; Immunobiology, Blizard Institute, London, UK., Kucykowicz S; Institute of Immunity and Transplantation, Division of Infection and Immunity, University College London, London, UK., Patel AM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Aliazis K; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Liu YS; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Reynolds GM; Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, UK.; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK., Davidson BR; Surgery, Royal Free Campus, UCL Medical School, London, UK., Gander A; Tissue Access for Patient Benefit, University College London, London, UK., Luong TV; Department of Cellular Pathology, Royal Free Hospital, London, UK., Hirschfield GM; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK.; Centre for Liver Research, National Institute for Health Research Biomedical Research Unit, University of Birmingham, Birmingham, UK., Kennedy PTF; Immunobiology, Blizard Institute, London, UK., Huang Y; Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China.; Guangdong Provincial Key Laboratory of Liver Disease Research, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, China., Maini MK; Division of Infection and Immunity, Rayne Institute, University College London, London, UK z.stamataki@bham.ac.uk m.maini@ucl.ac.uk., Stamataki Z; Centre for Liver and Gastrointestinal Research, University of Birmingham, Birmingham, UK z.stamataki@bham.ac.uk m.maini@ucl.ac.uk.

المصدر: Gut [Gut] 2022 Jul; Vol. 71 (7), pp. 1399-1411. Date of Electronic Publication: 2021 Sep 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: British Medical Assn Country of Publication: England NLM ID: 2985108R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1468-3288 (Electronic) Linking ISSN: 00175749 NLM ISO Abbreviation: Gut Subsets: MEDLINE

مواضيع طبية MeSH: CD4-Positive T-Lymphocytes* , Liver*/immunology, CD8-Positive T-Lymphocytes ; Cytokines/immunology ; Humans ; Immunologic Memory ; Monitoring, Immunologic

المؤلفون: Kucykowicz S; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Amin OE; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Burton AR; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Swadling L; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Schmidt NM; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Zakeri N; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Davies J; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Aidoo-Micah G; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Stegmann KA; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Easom NJ; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Jeffery-Smith A; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Maini MK; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK., Pallett LJ; Institute of Immunity and Transplantation, Division of Infection & Immunity, University College London, London, UK.

المصدر: STAR protocols [STAR Protoc] 2022 Apr 29; Vol. 3 (2), pp. 101356. Date of Electronic Publication: 2022 Apr 29 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: eCollection Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

مواضيع طبية MeSH: Leukocytes* , Lymphocytes*, Cell Separation/methods ; Flow Cytometry/methods ; Humans

المؤلفون: Diniz MO; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Schurich A; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Chinnakannan SK; Peter Medawar Building for Pathogen Research, Nuffield Dept of Medicine, University of Oxford, Oxford, UK., Duriez M; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Stegmann KA; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Davies J; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Kucykowicz S; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Suveizdyte K; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Amin OE; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Alcock F; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK., Cargill T; Peter Medawar Building for Pathogen Research, Nuffield Dept of Medicine, University of Oxford, Oxford, UK., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Dept of Medicine, University of Oxford, Oxford, UK., Maini MK; Division of Infection and Immunity and Institute of Immunity and Transplantation, UCL, London, UK.

المصدر: Science translational medicine [Sci Transl Med] 2022 Apr 13; Vol. 14 (640), pp. eabi4670. Date of Electronic Publication: 2022 Apr 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: B7-H1 Antigen*/metabolism , Vaccines*, Animals ; CD8-Positive T-Lymphocytes ; Cytokines/metabolism ; Killer Cells, Natural ; Mice ; Programmed Cell Death 1 Receptor/metabolism

المؤلفون: Zakeri N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Hall A; Institute for Liver & Digestive Health, Royal Free London NHS Foundation Trust, London, UK., Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Diniz MO; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Gander A; Division of Surgery, University College London, London, UK., Pinzani M; Institute for Liver & Digestive Health, Royal Free London NHS Foundation Trust, London, UK., Davidson BR; Division of Surgery, University College London, London, UK., Quaglia A; Department of Cellular Pathology, Royal Free London NHS Foundation Trust and UCL Cancer Institute, London, UK., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Mar 16; Vol. 13 (1), pp. 1372. Date of Electronic Publication: 2022 Mar 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/drug therapy , Liver Neoplasms*, Humans ; Lymphocyte Activation ; Receptors, Antigen, T-Cell, gamma-delta/metabolism ; T-Lymphocyte Subsets

المؤلفون: Swadling L; Division of Infection and Immunity, University College London, London, UK. l.swadling@ucl.ac.uk., Diniz MO; Division of Infection and Immunity, University College London, London, UK., Schmidt NM; Division of Infection and Immunity, University College London, London, UK., Amin OE; Division of Infection and Immunity, University College London, London, UK., Chandran A; Division of Infection and Immunity, University College London, London, UK., Shaw E; Division of Infection and Immunity, University College London, London, UK., Pade C; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Gibbons JM; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Le Bert N; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore., Tan AT; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore., Jeffery-Smith A; Division of Infection and Immunity, University College London, London, UK.; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Tan CCS; UCL Genetics Institute, University College London, London, UK., Tham CYL; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore., Kucykowicz S; Division of Infection and Immunity, University College London, London, UK., Aidoo-Micah G; Division of Infection and Immunity, University College London, London, UK., Rosenheim J; Division of Infection and Immunity, University College London, London, UK., Davies J; Division of Infection and Immunity, University College London, London, UK., Johnson M; Great Ormond Street Institute of Child Health NIHR Biomedical Research Centre, University College London, London, UK., Jensen MP; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Department of Cellular Pathology, Northwest London Pathology, Imperial College London NHS Trust, London, UK., Joy G; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., McCoy LE; Division of Infection and Immunity, University College London, London, UK., Valdes AM; Academic Rheumatology, Clinical Sciences, Nottingham City Hospital, Nottingham, UK.; NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and University of Nottingham, Nottingham, UK., Chain BM; Division of Infection and Immunity, University College London, London, UK., Goldblatt D; Great Ormond Street Institute of Child Health NIHR Biomedical Research Centre, University College London, London, UK., Altmann DM; Department of Immunology and Inflammation, Imperial College London, London, UK., Boyton RJ; Department of Infectious Disease, Faculty of Medicine, Imperial College London, London, UK.; Lung Division, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, London, UK., Manisty C; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., Treibel TA; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., Moon JC; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, London, UK., van Dorp L; UCL Genetics Institute, University College London, London, UK., Balloux F; UCL Genetics Institute, University College London, London, UK., McKnight Á; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Noursadeghi M; Division of Infection and Immunity, University College London, London, UK., Bertoletti A; Emerging Infectious Diseases Program, Duke-NUS Medical School, Singapore, Singapore.; Singapore Immunology Network, A*STAR, Singapore, Singapore., Maini MK; Division of Infection and Immunity, University College London, London, UK. m.maini@ucl.ac.uk.

مؤلفون مشاركون: COVIDsortium Investigators

المصدر: Nature [Nature] 2022 Jan; Vol. 601 (7891), pp. 110-117. Date of Electronic Publication: 2021 Nov 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Asymptomatic Infections* , Seroconversion*, COVID-19/*immunology , COVID-19/*virology , DNA-Directed RNA Polymerases/*immunology , Memory T Cells/*immunology , SARS-CoV-2/*immunology, Cell Proliferation ; Cohort Studies ; DNA-Directed RNA Polymerases/metabolism ; Evolution, Molecular ; Female ; Health Personnel ; Humans ; Male ; Membrane Proteins/immunology ; Memory T Cells/cytology ; Multienzyme Complexes/immunology ; SARS-CoV-2/enzymology ; SARS-CoV-2/growth & development ; Transcription, Genetic/immunology

المؤلفون: Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, United Kingdom., Colbeck EJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, United Kingdom., Daffis S; Gilead Sciences Inc., Foster City, CA., Khan S; Gilead Sciences Inc., Foster City, CA., Ramakrishnan D; Gilead Sciences Inc., Foster City, CA., Pattabiraman D; Gilead Sciences Inc., Foster City, CA., Chu R; Gilead Sciences Inc., Foster City, CA., Micolochick Steuer H; Gilead Sciences Inc., Foster City, CA., Lehar S; Gilead Sciences Inc., Foster City, CA., Peiser L; Gilead Sciences Inc., Foster City, CA., Palazzo A; Gilead Sciences Inc., Foster City, CA., Frey C; Gilead Sciences Inc., Foster City, CA., Davies J; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, United Kingdom., Javanbakht H; Gilead Sciences Inc., Foster City, CA., Rosenberg WMC; Institute for Liver and Digestive Health, University College London, London, United Kingdom., Fletcher SP; Gilead Sciences Inc., Foster City, CA., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, United Kingdom., Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, United Kingdom.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2021 Jul; Vol. 74 (1), pp. 55-71. Date of Electronic Publication: 2021 Jun 20.

نوع المنشور: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Antiviral Agents/*pharmacology , Hepatitis B, Chronic/*drug therapy , Hexanols/*pharmacology , Pyrimidines/*pharmacology , Toll-Like Receptor 8/*antagonists & inhibitors, Adult ; Aged ; Animals ; Antiviral Agents/therapeutic use ; CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/immunology ; Cohort Studies ; Disease Models, Animal ; Female ; Healthy Volunteers ; Hep G2 Cells ; Hepatitis B, Chronic/immunology ; Hepatitis B, Chronic/virology ; Hexanols/therapeutic use ; Host-Pathogen Interactions/drug effects ; Host-Pathogen Interactions/immunology ; Humans ; Killer Cells, Natural/drug effects ; Killer Cells, Natural/immunology ; Leukocytes, Mononuclear ; Male ; Marmota ; Middle Aged ; Primary Cell Culture ; Pyrimidines/therapeutic use ; T-Lymphocytes, Regulatory/drug effects ; T-Lymphocytes, Regulatory/immunology ; Toll-Like Receptor 8/metabolism ; Young Adult

المؤلفون: Schmidt NM; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Wing PAC; Nuffield Department of Medicine, Oxford University, Oxford, UK., Diniz MO; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pallett LJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Swadling L; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Harris JM; Nuffield Department of Medicine, Oxford University, Oxford, UK., Burton AR; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jeffery-Smith A; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Zakeri N; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Amin OE; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Kucykowicz S; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Heemskerk MH; Department of Hematology, Leiden University Medical Center, Leiden, The Netherlands., Davidson B; Division of Surgery, University College London, London, UK.; Royal Free London NHS Foundation Trust, London, UK., Meyer T; Royal Free London NHS Foundation Trust, London, UK.; Cancer Institute, University College London, London, UK., Grove J; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Stauss HJ; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Pineda-Torra I; Division of Medicine, University College London, London, UK., Jolly C; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK., Jury EC; Division of Medicine, University College London, London, UK., McKeating JA; Nuffield Department of Medicine, Oxford University, Oxford, UK., Maini MK; Division of Infection & Immunity, Institute of Immunity & Transplantation, University College London, London, UK. m.maini@ucl.ac.uk.

المصدر: Nature communications [Nat Commun] 2021 May 14; Vol. 12 (1), pp. 2814. Date of Electronic Publication: 2021 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Enzyme Inhibitors/*pharmacology , Hepatitis B virus/*drug effects , Sterol O-Acyltransferase/*antagonists & inhibitors , T-Lymphocytes/*drug effects , T-Lymphocytes/*metabolism, CD8-Positive T-Lymphocytes/drug effects ; CD8-Positive T-Lymphocytes/immunology ; CD8-Positive T-Lymphocytes/metabolism ; Carcinoma, Hepatocellular/drug therapy ; Carcinoma, Hepatocellular/virology ; Drug Therapy, Combination ; Enzyme Inhibitors/administration & dosage ; Hepatitis B virus/immunology ; Hepatitis B virus/pathogenicity ; Hepatitis B, Chronic/drug therapy ; Humans ; Immune Checkpoint Inhibitors/administration & dosage ; Immune Checkpoint Inhibitors/pharmacology ; In Vitro Techniques ; Liver/drug effects ; Liver/immunology ; Liver/virology ; Liver Neoplasms/drug therapy ; Liver Neoplasms/virology ; T-Lymphocytes/immunology

المؤلفون: Reynolds CJ; Department of Infectious Disease, Imperial College London, London, UK., Swadling L; Division of Infection and Immunity, University College London, London, UK., Gibbons JM; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Pade C; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Jensen MP; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Diniz MO; Division of Infection and Immunity, University College London, London, UK., Schmidt NM; Division of Infection and Immunity, University College London, London, UK., Butler DK; Department of Infectious Disease, Imperial College London, London, UK., Amin OE; Division of Infection and Immunity, University College London, London, UK., Bailey SNL; Department of Infectious Disease, Imperial College London, London, UK., Murray SM; Department of Infectious Disease, Imperial College London, London, UK., Pieper FP; Department of Infectious Disease, Imperial College London, London, UK., Taylor S; National Infection Service, Public Health England, Porton Down, UK., Jones J; National Infection Service, Public Health England, Porton Down, UK., Jones M; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Wolfson Institute of Preventive Medicine, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Lee WJ; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Rosenheim J; Division of Infection and Immunity, University College London, London, UK., Chandran A; Division of Infection and Immunity, University College London, London, UK., Joy G; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Di Genova C; Viral Pseudotype Unit, Medway School of Pharmacy, Chatham Maritime, Kent, UK., Temperton N; Viral Pseudotype Unit, Medway School of Pharmacy, Chatham Maritime, Kent, UK., Lambourne J; Department of Infection, Barts Health NHS Trust, London, UK., Cutino-Moguel T; Department of Virology, Barts Health NHS Trust, London, UK., Andiapen M; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK., Fontana M; Royal Free London NHS Foundation Trust, London, UK., Smit A; Royal Free London NHS Foundation Trust, London, UK., Semper A; National Infection Service, Public Health England, Porton Down, UK., O'Brien B; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; German Heart Centre and Charité University, Berlin, Germany., Chain B; Division of Infection and Immunity, University College London, London, UK., Brooks T; National Infection Service, Public Health England, Porton Down, UK., Manisty C; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, UK., Treibel T; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, UK., Moon JC; Barts Heart Centre, St Bartholomew's Hospital, Barts Health NHS Trust, London, UK.; Institute of Cardiovascular Science, University College London, UK., Noursadeghi M; Division of Infection and Immunity, University College London, London, UK., Altmann DM; Department of Immunology and Inflammation, Imperial College London, London, UK., Maini MK; Division of Infection and Immunity, University College London, London, UK., McKnight Á; Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Boyton RJ; Department of Infectious Disease, Imperial College London, London, UK. r.boyton@imperial.ac.uk.; Lung Division, Royal Brompton & Harefield NHS Foundation Trust, London, UK.

مؤلفون مشاركون: COVIDsortium investigators, COVIDsortium immune correlates network

المصدر: Science immunology [Sci Immunol] 2020 Dec 23; Vol. 5 (54).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Asymptomatic Infections*, Antibodies, Neutralizing/*immunology , COVID-19/*immunology , T-Lymphocytes/*immunology, Antibodies, Neutralizing/blood ; Antibodies, Viral/blood ; Antibodies, Viral/immunology ; Case-Control Studies ; Cross-Sectional Studies ; Humans ; SARS-CoV-2/immunology