المؤلفون: Yousef Yengej FA; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Pou Casellas C; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Ammerlaan CME; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Olde Hanhof CJA; Department of Medical BioSciences, Radboud Institute for Medical Innovation, 6525 GA Nijmegen, the Netherlands., Dilmen E; Department of Medical BioSciences, Radboud Institute for Medical Innovation, 6525 GA Nijmegen, the Netherlands., Beumer J; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW, 3584 CT Utrecht, the Netherlands; Institute of Human Biology, Roche Pharma Research and Early Development, 4058 Basel, Switzerland., Begthel H; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW, 3584 CT Utrecht, the Netherlands., Meeder EMG; Department of Psychiatry, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands., Hoenderop JG; Department of Medical BioSciences, Radboud Institute for Medical Innovation, 6525 GA Nijmegen, the Netherlands., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands. Electronic address: m.c.verhaar@umcutrecht.nl., Clevers H; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW & University Medical Center Utrecht, 3584 CT Utrecht, the Netherlands; Oncode Institute, Hubrecht Institute-KNAW, 3584 CT Utrecht, the Netherlands. Electronic address: h.clevers@hubrecht.eu.

المصدر: Cell reports [Cell Rep] 2024 Jan 23; Vol. 43 (1), pp. 113614. Date of Electronic Publication: 2023 Dec 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Lithium*/pharmacology , Aquaporin 2*, Adult ; Humans ; Nephrons ; Kidney ; Electrolytes ; Organoids

المؤلفون: Claus LR; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Chen C; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA., Stallworth J; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA., Turner JL; Department of Genetics and Biochemistry, Clemson University, Clemson, South Carolina, USA., Slaats GG; Department of Nephrology and Hypertension, Regenerative Medicine Center Utrecht, University Medical Center Utrecht, Utrecht, the Netherlands., Hawks AL; Department of Genetics and Biochemistry, Clemson University, Clemson, South Carolina, USA., Mabillard H; Newcastle University, Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Senum SR; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA., Srikanth S; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA., Flanagan-Steet H; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA., Louie RJ; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA., Silver J; Fred A. Litwin Family Centre in Genetic Medicine, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada., Lerner-Ellis J; Department of Molecular Genetics, University of Toronto, Toronto, Ontario, Canada; Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada., Morel C; Fred A. Litwin Family Centre in Genetic Medicine, University Health Network and Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Toronto, Ontario, Canada., Mighton C; Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, Canada; Lunenfeld-Tanenbaum Research Institute, Toronto, Ontario, Canada., Sleutels F; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., van Slegtenhorst M; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., van Ham T; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Brooks AS; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Dorresteijn EM; Department of Pediatric Nephrology, Erasmus University Medical Center, Sophia Children's Hospital, Rotterdam, the Netherlands., Barakat TS; Department of Clinical Genetics, Erasmus University Medical Center, Rotterdam, the Netherlands., Dahan K; Institute Pathology and Genetic, Center of Human Genetics, Charleroi, Belgium., Demoulin N; Division of Nephrology, Cliniques Universitaires Saint-Luc, Brussels, Belgium; Recherche Expérimentale et Clinique, UCLouvain, Brussels, Belgium., Goffin EJ; Division of Nephrology, Cliniques Universitaires Saint-Luc, Brussels, Belgium; Recherche Expérimentale et Clinique, UCLouvain, Brussels, Belgium., Olinger E; Newcastle University, Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Larsen M; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Hertz JM; Department of Clinical Genetics, Odense University Hospital, Odense, Denmark; Department of Clinical Research, University of Southern Denmark, Odense, Denmark., Lilien MR; Department of Pediatric Nephrology, Wilhelmina Children's Hospital, Utrecht, the Netherlands., Obeidová L; Institute of Biology and Medical Genetics, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic., Seeman T; Department of Pediatrics, 2nd Faculty of Medicine, Charles University, Prague, Czech Republic; Department of Pediatrics, University Hospital Ostrava, Ostrava, Czech Republic; Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic., Stone HK; Division of Nephrology and Hypertension, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA., Kerecuk L; Birmingham Women's and Children's National Health Services (NHS) Foundation Trust, National Institute for Health Care and Research (NIHR) Clinical Research Network (CRN) West Midlands, Birmingham, UK., Gurgu M; Fundeni Clinical Institute, Bucharest, Romania., Yousef Yengej FA; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, the Netherlands; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW, Utrecht, the Netherlands., Ammerlaan CME; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, the Netherlands; Hubrecht Institute for Developmental Biology and Stem Cell Research-KNAW, Utrecht, the Netherlands., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, the Netherlands., Hanna C; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA; Division of Pediatric Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA., Rogers RC; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA., Duran K; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Peters E; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Sayer JA; Newcastle University, Translational and Clinical Research Institute, Newcastle upon Tyne, UK; Renal Services, The Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle, UK; National Institute for Health and Care Research (NIHR) Biomedical Research Centre, Newcastle, UK., van Haaften G; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands., Harris PC; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA., Ling K; Department of Biochemistry and Molecular Biology, Mayo Clinic, Rochester, Minnesota, USA; Division of Nephrology and Hypertension, Mayo Clinic, Rochester, Minnesota, USA. Electronic address: Ling.Kun@mayo.edu., Mason JM; Department of Genetics and Biochemistry, Clemson University, Clemson, South Carolina, USA. Electronic address: jmason4@clemson.edu., van Eerde AM; Department of Genetics, University Medical Center Utrecht, Utrecht, the Netherlands. Electronic address: A.vanEerde@umcutrecht.nl., Steet R; Research Division, Greenwood Genetic Center, Greenwood, South Carolina, USA. Electronic address: rsteet@ggc.org.

مؤلفون مشاركون: Genomics England Research Consortium

المصدر: Kidney international [Kidney Int] 2023 Nov; Vol. 104 (5), pp. 995-1007. Date of Electronic Publication: 2023 Aug 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE

مواضيع طبية MeSH: Polycystic Kidney Diseases*/genetics , Polycystic Kidney, Autosomal Dominant*/pathology, Animals ; Humans ; Infant, Newborn ; Mice ; Carrier Proteins/metabolism ; Cilia/pathology ; Kidney/metabolism ; Mutation ; NIMA-Related Kinases/genetics ; NIMA-Related Kinases/metabolism ; Protein Serine-Threonine Kinases/genetics ; Protein Serine-Threonine Kinases/metabolism ; Serine/genetics ; Serine/metabolism ; TRPP Cation Channels/genetics ; TRPP Cation Channels/metabolism

المؤلفون: Yousef Yengej FA; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Jansen J; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands.; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Amalia Children's Hospital, GA 6525 Nijmegen, The Netherlands.; Institute of Experimental Medicine and Systems Biology, Rheinisch-Westfälische Technische Hogeschool (RWTH) Aachen University, 52074 Aachen, Germany., Ammerlaan CME; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Dilmen E; Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands., Pou Casellas C; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, CG 3584 Utrecht, The Netherlands., Hoenderop JG; Department of Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands., Smeets B; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, GA 6525 Nijmegen, The Netherlands., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, 3584 CX Utrecht, the Netherlands., Clevers H; Hubrecht Institute for Developmental Biology and Stem Cell Research - Royal Netherlands Academy of Arts and Sciences (KNAW) & University Medical Center Utrecht, 3584 CT and 3584 CX Utrecht, Netherlands.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2023 Feb 07; Vol. 120 (6), pp. e2216836120. Date of Electronic Publication: 2023 Feb 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/metabolism, Humans ; Kidney/metabolism ; Epithelium ; Organoids/metabolism ; Kidney Tubules ; Cell Differentiation

المؤلفون: Olde Hanhof CJA; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Dilmen E; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Yousef Yengej FA; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, Netherlands., Latta F; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Ammerlaan CME; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences, Utrecht, Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, Netherlands., Schreurs J; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Hooijmaijers L; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Jansen J; Department of Pathology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.; Department of Pediatric Nephrology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Amalia Children's Hospital, Nijmegen, Netherlands.; Institute of Experimental Medicine and Systems Biology, Medical Faculty RWTH Aachen University, Aachen, Germany., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, Netherlands., Orhon I; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, Netherlands., Hoenderop JG; Department of Molecular Physiology, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

المصدر: Frontiers in cell and developmental biology [Front Cell Dev Biol] 2023 Jan 25; Vol. 11, pp. 1086823. Date of Electronic Publication: 2023 Jan 25 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101630250 Publication Model: eCollection Cited Medium: Print ISSN: 2296-634X (Print) Linking ISSN: 2296634X NLM ISO Abbreviation: Front Cell Dev Biol Subsets: PubMed not MEDLINE

المؤلفون: Lindoso RS; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands.; Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil.; National Institute of Science and Technology for Regenerative Medicine-REGENERA, Federal University of Rio de Janeiro, Rio de Janeiro, 21941-902, Brazil., Yousef Yengej FA; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Voellmy F; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands., Altelaar M; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands., Mancheño Juncosa E; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands., Tsikari T; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands., Ammerlaan CME; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences, Utrecht, The Netherlands.; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Van Balkom BWM; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Centre Utrecht, Utrecht, The Netherlands., Masereeuw R; Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Universiteitsweg 99, 3584 CG, Utrecht, The Netherlands. R.Masereeuw@uu.nl.

المصدر: Journal of nanobiotechnology [J Nanobiotechnology] 2022 Jul 15; Vol. 20 (1), pp. 326. Date of Electronic Publication: 2022 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101152208 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-3155 (Electronic) Linking ISSN: 14773155 NLM ISO Abbreviation: J Nanobiotechnology Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles*/metabolism , Proteomics*, Epithelial Cells ; Kidney/metabolism ; Kidney Tubules, Proximal/metabolism

المؤلفون: Gijzen L; Mimetas BV, Leiden, the Netherlands., Yousef Yengej FA; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands., Schutgens F; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands., Vormann MK; Mimetas BV, Leiden, the Netherlands., Ammerlaan CME; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands., Nicolas A; Mimetas BV, Leiden, the Netherlands., Kurek D; Mimetas BV, Leiden, the Netherlands., Vulto P; Mimetas BV, Leiden, the Netherlands., Rookmaaker MB; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands., Lanz HL; Mimetas BV, Leiden, the Netherlands., Verhaar MC; Department of Nephrology and Hypertension, University Medical Center Utrecht, Utrecht, the Netherlands., Clevers H; Hubrecht Institute-Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Utrecht, the Netherlands. h.clevers@hubrecht.eu.

المصدر: Nature protocols [Nat Protoc] 2021 Apr; Vol. 16 (4), pp. 2023-2050. Date of Electronic Publication: 2021 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101284307 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1750-2799 (Electronic) Linking ISSN: 17502799 NLM ISO Abbreviation: Nat Protoc Subsets: MEDLINE

مواضيع طبية MeSH: Lab-On-A-Chip Devices* , Perfusion*, Kidney Tubules/*growth & development , Organoids/*growth & development , Tissue Culture Techniques/*methods, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Cell Fractionation ; Child ; Child, Preschool ; Electric Impedance ; Female ; Fluorescent Dyes/chemistry ; Humans ; Infant ; Male ; Membrane Transport Proteins/metabolism ; Microfluidics ; Middle Aged ; Rats ; Young Adult