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المؤلفون: Jens Praestgaard, Daniel Rooks, Amy Berwick, Ronenn Roubenoff, Hanns-Christian Tillmann, Michael C Steiner, Dave Singh, Michael I. Polkey, Richard Casaburi, Frits M.E. Franssen, Estelle Lach-Trifilieff
المصدر: American journal of respiratory and critical care medicine, vol 199, iss 3
مصطلحات موضوعية: Male, Activin Receptors, Respiratory System, lean body mass, Myostatin, Pharmacology, Critical Care and Intensive Care Medicine, Medical and Health Sciences, bimagrumab, Muscle hypertrophy, Pulmonary Disease, Chronic Obstructive, Monoclonal, 80 and over, Respiratory system, Receptor, Humanized, Lung, Aged, 80 and over, COPD, biology, Antibodies, Monoclonal, Skeletal, Middle Aged, musculoskeletal system, Blocking, Muscular Atrophy, medicine.anatomical_structure, Thigh, 6.1 Pharmaceuticals, Body Composition, Respiratory, Muscle, Female, Adult, Pulmonary and Respiratory Medicine, Chronic Obstructive, medicine.drug_class, Chronic Obstructive Pulmonary Disease, Clinical Trials and Supportive Activities, Antibodies, Monoclonal, Humanized, Monoclonal antibody, Antibodies, Pulmonary Disease, Double-Blind Method, Clinical Research, medicine, Humans, Antibodies, Blocking, Muscle, Skeletal, Bimagrumab, Aged, thigh muscle volume, business.industry, 6-minute-walk distance, Evaluation of treatments and therapeutic interventions, Skeletal muscle, medicine.disease, Musculoskeletal, biology.protein, business
وصف الملف: application/pdf
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المؤلفون: Gabi Schutzius, Michael Faller, Aimee Reynolds, Ralph Tiedt, Julia Klopp, Florian Fuchs, Laure C. Bouchez, Federico Tortelli, Nelly Leroy, Jonathan J. Turner, Guglielmo Roma, Simona Cotesta, Armin Beyerbach, Peter Drueckes, Shola M Richards, Debora Bonenfant, Heinrich Rueeger, Heinz Ruffner, Jutta Blank, Rémi Terranova, Peter Tarsa, Frederic Grandjean, Florian Nigsch, Sebastian Bergling, Natalie Dales, Alexandra Aebi, Paul W. Manley, Markus Schirle, Christian Kolter, Tewis Bouwmeester, Rene Hemmig, Sukhdeep Sahambi, Lori L. Jennings, Walter Carbone, Felix Lohmann, Alfred Zimmerlin, Jun Li, Susan Kirkland, Steffen Renner, Mathias Frederiksen, Vickie Driver, Amy Berwick, Florence Zink, Jason R. Thomas, Andrea Vaupel, Chris Dimitri, Vito Guagnano, Viktoria Gruber, Malvina Louis, Caroline Gubser Keller, Adrian Salathe
المصدر: Nature chemical biology. 17(3)
مصطلحات موضوعية: Keratinocytes, Male, Protein family, Transcription, Genetic, Phenotypic screening, Primary Cell Culture, Cell Cycle Proteins, Wounds, Nonpenetrating, Small Molecule Libraries, 03 medical and health sciences, Mice, Structure-Activity Relationship, Re-Epithelialization, In vivo, Skin Ulcer, medicine, Fluorescence Resonance Energy Transfer, Animals, Humans, Protein Isoforms, Protein Precursors, Molecular Biology, 030304 developmental biology, 0303 health sciences, integumentary system, Epidermis (botany), business.industry, 030302 biochemistry & molecular biology, Cell Biology, In vitro, Bromodomain, High-Throughput Screening Assays, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Cancer research, Epidermis, Keratinocyte, business, Ex vivo, Transcription Factors
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المؤلفون: Tjalf Ziemssen, Amy Berwick, Hisanori Hara, Robert Schmouder, Peng Li, Michael Lang, Olivier J. David, Klaus Tiel-Wilck, Nicole Pezous
المصدر: Clinical Pharmacology in Drug Development
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Multiple Sclerosis, Cmax, Pharmaceutical Science, fingolimod‐phosphate, Semen, Gastroenterology, Phosphates, 03 medical and health sciences, 0302 clinical medicine, blood, Internal medicine, medicine, Humans, Pharmacology (medical), 030212 general & internal medicine, fingolimod, Active metabolite, Fetus, Fingolimod Hydrochloride, business.industry, Brief Report, Multiple sclerosis, semen, Middle Aged, medicine.disease, Fingolimod, Safety profile, Male patient, business, Immunosuppressive Agents, 030217 neurology & neurosurgery, medicine.drug
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المؤلفون: Amy Berwick, Ream Al-Hasani, Athanasios Metaxas, Pamela Farshim, Susanna M.O. Hourani, Kristina Tubby, Alexis Bailey, Catherine Ledent, Ian Kitchen
المساهمون: Radiology and nuclear medicine, NCA - Brain imaging technology
المصدر: Neuropharmacology, 71, 228-236. Elsevier Limited
Metaxas, A, Al-Hasani, R, Farshim, P, Tubby, K, Berwick, A, Ledent, C, Hourani, S, Kitchen, I & Bailey, A 2013, ' Genetic deletion of the adenosine A(2A) receptor prevents nicotine-induced upregulation of alpha 7, but not alpha 4 beta 2*nicotinic acetylcholine receptor binding in the brain ', Neuropharmacology, vol. 71, pp. 228-236 . https://doi.org/10.1016/j.neuropharm.2013.03.023مصطلحات موضوعية: Male, Nicotine, medicine.medical_specialty, Receptor, Adenosine A2A, alpha7 Nicotinic Acetylcholine Receptor, Pyridines, Adenosine A2A receptor, Mice, Inbred Strains, Nerve Tissue Proteins, Receptors, Nicotinic, Pharmacology, Mice, Cellular and Molecular Neuroscience, Downregulation and upregulation, Internal medicine, medicine, Animals, Nicotinic Agonists, Cotinine, Receptor, Mice, Knockout, Neurons, Chemistry, Brain, Tobacco Use Disorder, Bridged Bicyclo Compounds, Heterocyclic, Bungarotoxins, Up-Regulation, Protein Subunits, Nicotinic acetylcholine receptor, Nicotinic agonist, Endocrinology, Epibatidine, Knockout mouse, medicine.drug
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