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المؤلفون: Ghotas Evindar, Amy Hutchings, Jeanine Lorusso, Albion D. Wright, Michael Kelley, Sylvie G. Bernier, Keith Halley, Barry A. Morgan, William F. Westlin, Elisabeth Doyle, Nazbeh Taghizadeh, Gerhard Hannig, Alexander L. Satz, Malcolm J. Kavarana, Ashis K. Saha
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:2315-2319
مصطلحات موضوعية: Agonist, medicine.drug_class, Sphingosine-1-phosphate receptor, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Biochemistry, Chemical synthesis, Mice, chemistry.chemical_compound, Sphingosine, In vivo, Drug Discovery, medicine, Animals, Potency, Sphingosine-1-phosphate, Receptor, Molecular Biology, Dose-Response Relationship, Drug, Fingolimod Hydrochloride, Chemistry, Organic Chemistry, Imidazoles, Amides, In vitro, Protein Subunits, Receptors, Lysosphingolipid, Propylene Glycols, Molecular Medicine
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المؤلفون: Albion D. Wright, Ashis K. Saha, Jeanine Lorusso, Michael Kelley, Ghotas Evindar, Barry A. Morgan, Elisabeth Doyle, Amy Hutchings, Malcolm J. Kavarana, William F. Westlin, Gerhard Hannig, Sylvie G. Bernier, Keith Halley
المصدر: Bioorganicmedicinal chemistry letters. 19(2)
مصطلحات موضوعية: Stereochemistry, Sphingosine-1-phosphate receptor, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, chemistry.chemical_compound, Mice, Structure-Activity Relationship, In vivo, Drug Discovery, Molecule, Animals, Humans, Sphingosine-1-phosphate, Receptor, Molecular Biology, Dose-Response Relationship, Drug, Chemistry, Organic Chemistry, Imidazoles, Amides, Receptors, Lysosphingolipid, Alkoxy group, Molecular Medicine, Selectivity