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1دورية أكاديمية
المؤلفون: Sanchari Bhattacharyya, Shimon Bershtein, Jin Yan, Tijda Argun, Amy I Gilson, Sunia A Trauger, Eugene I Shakhnovich
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: gene dosage toxicity, protein-protein interactions, protein crowding in cytoplasm, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2
المؤلفون: Eugene I. Shakhnovich, Sanchari Bhattacharyya, Amy I. Gilson, Bharat V. Adkar, Wenli Zhang
مصطلحات موضوعية: Mutant, Adenylate kinase, 03 medical and health sciences, Negative selection, Enzyme Stability, Escherichia coli, 030304 developmental biology, 0303 health sciences, Multidisciplinary, biology, Chemistry, Protein Stability, Escherichia coli Proteins, 030302 biochemistry & molecular biology, Adenylate Kinase, Active site, Substrate (chemistry), Biomolecules (q-bio.BM), Enzyme assay, ADK, Kinetics, PNAS Plus, Quantitative Biology - Biomolecules, FOS: Biological sciences, Mutation, biology.protein, Biophysics, Thermodynamics, Flux (metabolism)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fc462cb5fb00687538df8bd71447864
http://arxiv.org/abs/1812.07430 -
3
المؤلفون: Alexandra Snyder, Samuel Funt, Christian Borgs, Mark D.M. Leiserson, Lester Mackey, Miroslav Dudík, Jonathan Rosenberg, Vasilis Syrgkanis, Jennifer Chayes, Sharon Gillett, Dean F. Bajorin, Amy I. Gilson
المساهمون: Ahmad, Aamir
المصدر: PLoS ONE, Vol 13, Iss 12, p e0208422 (2018)
PloS one, vol 13, iss 12
PLoS ONEمصطلحات موضوعية: Male, Oncology, Carcinogenesis, medicine.medical_treatment, Biochemistry, Biomarkers, Pharmacological, 0302 clinical medicine, Cancer immunotherapy, Animal Cells, Models, Medicine, Lymphocytes, Immune Response, Cancer, 0303 health sciences, Tumor, Cell Cycle, Antibodies, Monoclonal, Explained variation, 3. Good health, Blood, 5.1 Pharmaceuticals, 030220 oncology & carcinogenesis, Monoclonal, Immunotherapy, Cellular Types, Development of treatments and therapeutic interventions, medicine.medical_specialty, Immune Cells, Science, T cell, Immunology, Risk Assessment, 03 medical and health sciences, Lymphocytes, Tumor-Infiltrating, Humans, Tumor-Infiltrating, Models, Statistical, Blood Cells, Bladder cancer, Biology and Life Sciences, medicine.disease, 030104 developmental biology, Urinary Bladder Neoplasms, Mutation, Clinical Medicine, Transitional Cell, Biomarkers, B7-H1 Antigen, 0301 basic medicine, Physiology, T-Lymphocytes, Cancer Treatment, White Blood Cells, Medicine and Health Sciences, Humanized, Multidisciplinary, T Cells, Statistical, Cell cycle, Regression, Body Fluids, Treatment Outcome, medicine.anatomical_structure, Mutation (genetic algorithm), Female, Anatomy, Research Article, Adult, General Science & Technology, Urology, Antibodies, Monoclonal, Humanized, Cancer Immunotherapy, Antibodies, Clonal Evolution, Immune system, Internal medicine, Biomarkers, Tumor, Protein Kinase Inhibitors, Cell Proliferation, 030304 developmental biology, Carcinoma, Transitional Cell, Cell growth, business.industry, Carcinoma, Pharmacological, Cell Biology, Immune System, Cancer research, Clinical Immunology, business, PD-L1 inhibitor
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03bfdc9fee1d876c13bff854fab18a2
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مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Protein family, Protein domain, Biophysics, Analogy, Biology, Protein Structure, Secondary, Evolution, Molecular, 03 medical and health sciences, Structure-Activity Relationship, 0302 clinical medicine, Protein structure, Protein Domains, Rare events, Computer Simulation, Homology modeling, Selection, Genetic, Evolutionary dynamics, Quantitative Biology - Populations and Evolution, Selection (genetic algorithm), 030304 developmental biology, Physics, 0303 health sciences, Protein Stability, Populations and Evolution (q-bio.PE), Proteins, Biomolecules (q-bio.BM), Contact density, Sequence identity, Divergent evolution, 030104 developmental biology, Quantitative Biology - Biomolecules, Evolutionary biology, FOS: Biological sciences, Protein folding, Evolutionary selection, Monte Carlo Method, 030217 neurology & neurosurgery, Intuition
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c86f933ba1bb0ae173ad63767cafb6b
https://europepmc.org/articles/PMC5390048/ -
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المؤلفون: Eugene I. Shakhnovich, Jeong-Mo Choi, Amy I. Gilson
المصدر: Physical review letters. 118(8)
مصطلحات موضوعية: Physics, Statistical Mechanics (cond-mat.stat-mech), Spin system, FOS: Physical sciences, General Physics and Astronomy, Biomolecules (q-bio.BM), Topology, 01 natural sciences, Article, 010305 fluids & plasmas, Graph energy, Quantitative Biology - Biomolecules, FOS: Biological sciences, 0103 physical sciences, Lattice protein, Spin model, Graph (abstract data type), Free energies, Metal lattice, 010306 general physics, Linear equation, Condensed Matter - Statistical Mechanics
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المؤلفون: Tijda Argun, Sanchari Bhattacharyya, Sunia A. Trauger, Shimon Bershtein, Eugene I. Shakhnovich, Amy I. Gilson, Jin Yan
مصطلحات موضوعية: Biochemistry, Chemistry, Toxicity, Metabolome, Transient (computer programming), Gene dosage, Protein–protein interaction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2dd46857ceab8af88a67800ef2858fe9
https://doi.org/10.7554/elife.20309.026 -
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المؤلفون: Sunia A. Trauger, Eugene I. Shakhnovich, Amy I. Gilson, Jin Yan, Sanchari Bhattacharyya, Tijda Argun, Shimon Bershtein
المصدر: eLife, Vol 5 (2016)
eLifeمصطلحات موضوعية: 0301 basic medicine, Gene Dosage, protein-protein interactions, protein crowding in cytoplasm, Endogeny, Plasma protein binding, medicine.disease_cause, Protein Interaction Maps, Biology (General), Genetics, chemistry.chemical_classification, 0303 health sciences, Chemistry, Escherichia coli Proteins, General Neuroscience, 030302 biochemistry & molecular biology, General Medicine, Biophysics and Structural Biology, Recombinant Proteins, Cell biology, Proteome, Metabolome, Medicine, Metabolon, Research Article, Computational and Systems Biology, Protein Binding, QH301-705.5, Science, Systems biology, Biology, Gene dosage, General Biochemistry, Genetics and Molecular Biology, gene dosage toxicity, Protein–protein interaction, 03 medical and health sciences, parasitic diseases, Escherichia coli, medicine, Gene, 030304 developmental biology, General Immunology and Microbiology, E. coli, Metabolism, Tetrahydrofolate Dehydrogenase, 030104 developmental biology, Enzyme, Structural biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37e9efabb7b3d61525f5f7bb669ee90f
https://doi.org/10.1101/066373 -
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المؤلفون: Nurit Livnat-Levanon, Nir Ben-Tal, Amy I. Gilson, Oded Lewinson
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Conformational change, Protein Conformation, ATPase, Biological Transport, Active, ATP-binding cassette transporter, Article, 03 medical and health sciences, Adenosine Triphosphate, ATP hydrolysis, Escherichia coli, chemistry.chemical_classification, Adenosine Triphosphatases, Multidisciplinary, biology, Chemistry, Escherichia coli Proteins, Hydrolysis, Transporter, Kinetics, 030104 developmental biology, Enzyme, Biochemistry, Liposomes, biology.protein, ATP-Binding Cassette Transporters, Energy source, ATP synthase alpha/beta subunits, Protein Binding
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المؤلفون: Amy I. Gilson, Rémi Monasson, Eugene I. Shakhnovich, Hugo Jacquin, Simona Cocco
المصدر: PLoS Computational Biology
PLoS Computational Biology, Vol 12, Iss 5, p e1004889 (2016)مصطلحات موضوعية: 0301 basic medicine, Protein Structure Comparison, Models, Molecular, Protein Folding, Computer science, Protein Conformation, Entropy, Inference, Inverse, Protein Structure Prediction, Protein Sequencing, 01 natural sciences, Quantitative Biology - Quantitative Methods, Biochemistry, Protein sequencing, Protein structure, Mathematical and Statistical Techniques, Lattice protein, Statistics, Macromolecular Structure Analysis, Statistical physics, lcsh:QH301-705.5, Quantitative Methods (q-bio.QM), Mathematics, 0303 health sciences, Quantitative Biology::Biomolecules, Ecology, Physics, Protein structure prediction, Benchmarking, Computational Theory and Mathematics, Biological Physics (physics.bio-ph), Modeling and Simulation, Physical Sciences, symbols, Thermodynamics, Protein folding, Hamiltonian (quantum mechanics), Sequence Analysis, Statistics (Mathematics), Research Article, Protein Structure, Multiple Alignment Calculation, FOS: Physical sciences, Sequence alignment, Research and Analysis Methods, symbols.namesake, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0103 physical sciences, Computational Techniques, Genetics, Computer Simulation, Physics - Biological Physics, Amino Acid Sequence, Statistical Methods, 010306 general physics, Molecular Biology Techniques, Sequencing Techniques, Native structure, Molecular Biology, Ecology, Evolution, Behavior and Systematics, Condensed Matter - Statistical Mechanics, 030304 developmental biology, Coupling, Models, Statistical, Statistical Mechanics (cond-mat.stat-mech), Biology and Life Sciences, Proteins, Computational Biology, Biomolecules (q-bio.BM), Split-Decomposition Method, 030104 developmental biology, lcsh:Biology (General), Quantitative Biology - Biomolecules, FOS: Biological sciences, Pairwise comparison, Sequence Alignment, Forecasting
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b65790ae7800cc7e107a076935ac09d4
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المؤلفون: Martin Head-Gordon, Westin Kurlancheek, Amy I. Gilson, Gilles Frison, Guillaume van der Rest, Julia Chamot-Rooke, Denis Jacquemin
المساهمون: Laboratoire des mécanismes réactionnels (DCMR), École polytechnique (X)-Institut de Chimie du CNRS (INC)-Centre National de la Recherche Scientifique (CNRS), Department of Chemistry [Berkeley], University of California [Berkeley], University of California-University of California, Chimie Et Interdisciplinarité : Synthèse, Analyse, Modélisation (CEISAM), Université de Nantes - UFR des Sciences et des Techniques (UN UFR ST), Université de Nantes (UN)-Université de Nantes (UN)-Centre National de la Recherche Scientifique (CNRS)-Institut de Chimie du CNRS (INC)
المصدر: Journal of Physical Chemistry Letters
Journal of Physical Chemistry Letters, American Chemical Society, 2011, 2, pp.1426-1431. ⟨10.1021/jz2004792⟩مصطلحات موضوعية: charge localization, Electron density, Electron capture, Electron, 010402 general chemistry, 01 natural sciences, radical ion, Delocalized electron, Electron transfer, [CHIM.ANAL]Chemical Sciences/Analytical chemistry, Computational chemistry, Electron affinity, 0103 physical sciences, General Materials Science, Physics::Chemical Physics, Physical and Theoretical Chemistry, mass spectrometry, 010304 chemical physics, Chemistry, ECD/ETD, Electron localization function, 0104 chemical sciences, ammonium, [CHIM.THEO]Chemical Sciences/Theoretical and/or physical chemistry, Unpaired electron, Chemical physics, self-interaction error, gas phase