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المؤلفون: Anandan Palani, Andrea R. Nawrocki, Federica Orvieto, Elisabetta Bianchi, Emanuela Mandić, Antonello Pessi, Chunhui Huang, Qiaolin Deng, Nathalie Toussaint, Erika Walsh, Vijay Reddy, Eric Ashley, Huaibing He, Sheena Mumick, Brian Hawes, Donald Marsh, Mark Erion, Ravi Nargund, Paul E. Carrington
المصدر: ACS Medicinal Chemistry Letters. 13:1248-1254
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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المؤلفون: Chunhui Huang, Anandan Palani, Zhiqiang Yang, Qiaolin Deng, Vijay Reddy, Ravi P. Nargund, Songnian Lin, Simona Altezza, Elisabetta Bianchi, Federica Orvieto, Paul Carrington
المصدر: ACS Medicinal Chemistry Letters. 13:1255-1261
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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3
المؤلفون: Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers
المصدر: Journal of Medicinal Chemistry. 65:485-496
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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4
المؤلفون: Anandan Palani, Matthew Lloyd Childers, Qinglin Pu, Matthew J. Mitcheltree, Symon Gathiaka, Christian Fischer, Lisa Nogle, Rachel L. Palte, Jared N. Cumming, J. Richard Miller, Spencer McMinn, Hai-Young Kim, Hongjun Zhang, Charles A. Lesburg, Adam Beard, Donovon A. Adpressa, Josep Saurí, Derun Li, Theodore A. Martinot, Thomas W. Lyons, David L. Sloman, Jialiang Wang, Peter Spacciapoli, Min Lu, Abdelghani Achab
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Arginase, Bicyclic molecule, Stereochemistry, Chemistry, Organic Chemistry, Drug Discovery, Proline, Biochemistry
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المؤلفون: Matthew J. Mitcheltree, Theodore A. Martinot, Thomas W. Lyons, Spencer McMinn, Peter W. Fan, Hyelim Cho, Christian Fischer, Kalyan Chakravarthy, David L. Sloman, Padmanabhan Eangoor, Jared N. Cumming, Charles A. Lesburg, Mangeng Cheng, Adam Beard, Derun Li, Hongjun Zhang, Jennifer O'Neil, Abdelghani Achab, Rachel L. Palte, Anandan Palani, J. Richard Miller, Josep Saurí, Symon Gathiaka, Hai-Young Kim
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Tumor microenvironment, Arginine, Bicyclic molecule, 010405 organic chemistry, medicine.medical_treatment, Immune checkpoint inhibitors, Organic Chemistry, Ornithine, Pharmacology, 01 natural sciences, Biochemistry, 0104 chemical sciences, Bioavailability, Arginase, 010404 medicinal & biomolecular chemistry, chemistry.chemical_compound, chemistry, Cancer immunotherapy, Drug Discovery, medicine
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المؤلفون: Lili Zhang, Li Xiao, Diane Rindgen, Mihirbaran Mandal, John P. Caldwell, Xiaoxiang Liu, Anandan Palani, Zhaoning Zhu, Alexei V. Buevich, Dmitri A. Pissarnitski, Eric M. Parker, Robert Mazzola, Lynn A. Hyde, Xianhai Huang, Mckittrick Brian A
المصدر: Journal of medicinal chemistry. 63(15)
مصطلحات موضوعية: chemistry.chemical_classification, Oxadiazoles, Amyloid beta-Peptides, Binding Sites, Double bond, Stereochemistry, Alkenes, In vitro, Peptide Fragments, Rats, chemistry.chemical_compound, Structure-Activity Relationship, HEK293 Cells, chemistry, Nucleophile, Drug Discovery, Molecular Medicine, Moiety, Structure–activity relationship, Animals, Humans, Reactivity (chemistry), γ secretase, Azepine, Amyloid Precursor Protein Secretases
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المؤلفون: Craig C. Correll, Robert G. Aslanian, Li Xiao, Rema Bitar, Wei Zhou, John W. Butcher, Charles G. Garlisi, Joshua Close, Rachel N. Maccoss, Joon Jung, Scott Crawford, Kevin M. Maloney, Purakkattle Biju, Anandan Palani, Xianhai Huang, Xiaoxin Yang, Kevin D. McCormick, Scott Peterson, Hongjun Zhang, Diane Rindgen, Ying Huang, Alexei V. Buevich, Ning Shao, Li Dong, Phieng Siliphaivanh, Jason D. Brubaker, Michelle Martinez, Hongchen Qiu, François G. Gervais, Ravi P. Nargund, Zhidan Liu
المصدر: ACS Medicinal Chemistry Letters. 9:679-684
مصطلحات موضوعية: 0301 basic medicine, Drug, chemistry.chemical_classification, 010405 organic chemistry, Chemistry, medicine.drug_class, media_common.quotation_subject, Organic Chemistry, Pharmacology, medicine.disease, Receptor antagonist, 01 natural sciences, Biochemistry, 0104 chemical sciences, 03 medical and health sciences, 030104 developmental biology, Pharmacokinetics, Drug Discovery, medicine, Antagonism, Crth2 antagonist, Receptor, media_common, Asthma, Tricyclic
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8
المؤلفون: Federica Orvieto, Antonello Pessi, Brian Hawes, Paul E. Carrington, Licia Tomei, Armin Lahm, Sheena Mumick, Anandan Palani, Francesco Frattolillo, Valentina Di Biasio, Elisabetta Bianchi, Anna Demartis, Elisa Beghetto
المصدر: Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Scientific Reportsمصطلحات موضوعية: 0301 basic medicine, Phage display, Dipeptidyl Peptidase 4, lcsh:Medicine, Peptide, Computational biology, Glucagon, Glucagon-Like Peptide-1 Receptor, Article, Dipeptidyl peptidase, 03 medical and health sciences, 0302 clinical medicine, Peptide Library, In vivo, Diabetes Mellitus, Receptors, Glucagon, Humans, Obesity, Receptor, Peptide library, lcsh:Science, Glucagon-like peptide 1 receptor, chemistry.chemical_classification, Multidisciplinary, lcsh:R, Sequence Analysis, DNA, 030104 developmental biology, chemistry, Polypharmacy, lcsh:Q, Peptides, 030217 neurology & neurosurgery
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المؤلفون: Ravi P. Nargund, Li-Kang Zhang, Xiaoxin Yang, Hongchen Qiu, Anandan Palani, Xianhai Huang, Craig C. Correll, Robert G. Aslanian, Wei Zhou, Ashwin U. Rao, Alexei V. Buevich, Charles G. Garlisi
المصدر: Bioorganic & Medicinal Chemistry Letters. 27:5344-5348
مصطلحات موضوعية: 010405 organic chemistry, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Intramolecular cyclization, Pharmaceutical Science, 010402 general chemistry, 01 natural sciences, Biochemistry, Combinatorial chemistry, 0104 chemical sciences, Catalysis, Drug Discovery, Molecular Medicine, Structure–activity relationship, Molecular Biology
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المؤلفون: Richard Soll, Peng Li, Jin Wu, Peter T. Meinke, David B. Olsen, Anandan Palani, Ajay Ummat, Wei Chang, Nigel J. Liverton, M. Katharine Holloway, Xuanjia Peng, Casey C. Mccomas, Jie Wu, Charles A. Lesburg, Nicolas Zorn, Steven W. Ludmerer
المصدر: ChemMedChem. 12:1436-1448
مصطلحات موضوعية: 0301 basic medicine, Pan troglodytes, Hepacivirus, 030106 microbiology, Mutant, Viral Nonstructural Proteins, Pharmacology, Antiviral Agents, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Drug Discovery, medicine, Animals, Humans, Potency, Dosing, General Pharmacology, Toxicology and Pharmaceutics, NS5B, Benzofurans, biology, Organic Chemistry, Hepatitis C, biology.organism_classification, medicine.disease, Virology, Rats, Molecular Docking Simulation, chemistry, Molecular Medicine, Nucleoside, Viral load