المؤلفون: Chauhan S; Children's Cancer Therapy Development Institute, 9025 NE Von Neumann Drive Ste 110, Hillsboro, OR, 97006, USA., Lian E; Children's Cancer Therapy Development Institute, 9025 NE Von Neumann Drive Ste 110, Hillsboro, OR, 97006, USA., Habib I; Champions Oncology, Rockville, MD, 20850, USA., Liu Q; Department of Epidemiology and Biostatistics, University of Texas Health Science Center San Antonio, San Antonio, TX, 78229, USA., Anders NM; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, MD, 21231, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, 21231, USA.; Takeda Pharmaceutical Company, San Diego, CA, 92121, USA., Bugg MM; Children's Cancer Therapy Development Institute, 9025 NE Von Neumann Drive Ste 110, Hillsboro, OR, 97006, USA., Federman NC; Jonsson Comprehensive Cancer Center, University of California Los Ángeles, Los Angeles, CA, USA.; Department of Pediatrics, University of California, Los Angeles, Los Angeles, CA, USA., Reid JM; Mayo Clinic Comprehensive Cancer Center, Rochester, MN, 55905, USA., Stewart CF; Pharmacy and Pharmaceutical Sciences, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Cates T; Champions Oncology, Rockville, MD, 20850, USA., Michalek JE; Department of Epidemiology and Biostatistics, University of Texas Health Science Center San Antonio, San Antonio, TX, 78229, USA., Keller C; Children's Cancer Therapy Development Institute, 9025 NE Von Neumann Drive Ste 110, Hillsboro, OR, 97006, USA. charles@cc-tdi.org.

المصدر: Scientific reports [Sci Rep] 2024 Aug 15; Vol. 14 (1), pp. 18936. Date of Electronic Publication: 2024 Aug 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Pyridines*/pharmacology , Pyridines*/therapeutic use , Benzamides*/therapeutic use , Benzamides*/pharmacology , Rhabdomyosarcoma*/drug therapy , Rhabdomyosarcoma*/genetics , Rhabdomyosarcoma*/pathology , Rhabdomyosarcoma*/metabolism , Xenograft Model Antitumor Assays*, Humans ; Animals ; Mice ; Cell Line, Tumor ; Histone Deacetylase Inhibitors/pharmacology ; Histone Deacetylase Inhibitors/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/pharmacology

المؤلفون: Paller CJ; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Zahurak ML; Division of Biostatistics and Bioinformatics, Johns Hopkins University, Baltimore, Maryland., Mandl A; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Metri NA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Lalji A; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Heath E; Barbara Ann Karmanos Cancer Institute, Detroit, Michigan., Kelly WK; Thomas Jefferson University, Philadelphia, Pennsylvania., Hoimes C; Duke Cancer Institute, Durham, North Carolina., Barata P; Case Western Reserve University/University Hospitals, Cleveland, Ohio., Taksey J; Maryland Oncology Hematology, US Oncology, Annapolis, Maryland., Garrison DA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Patra K; Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland., Milne GL; Division of Clinical Pharmacology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Anders NM; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Nauroth JM; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Durham JN; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Marshall CH; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Markowski MC; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Eisenberger MA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Antonarakis ES; University of Minnesota Masonic Cancer Center, Minneapolis, Minnesota., Carducci MA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Denmeade SR; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland., Levine M; Molecular and Clinical Nutrition Section, Digestive Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland.

المصدر: Cancer research communications [Cancer Res Commun] 2024 Aug 01; Vol. 4 (8), pp. 2174-2182.

نوع المنشور: Journal Article; Clinical Trial, Phase II; Randomized Controlled Trial

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9918281580506676 Publication Model: Print Cited Medium: Internet ISSN: 2767-9764 (Electronic) Linking ISSN: 27679764 NLM ISO Abbreviation: Cancer Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: Docetaxel*/administration & dosage , Docetaxel*/therapeutic use , Prostatic Neoplasms, Castration-Resistant*/drug therapy , Prostatic Neoplasms, Castration-Resistant*/pathology , Prostatic Neoplasms, Castration-Resistant*/mortality , Ascorbic Acid*/administration & dosage , Ascorbic Acid*/therapeutic use , Ascorbic Acid*/adverse effects , Antineoplastic Combined Chemotherapy Protocols*/therapeutic use , Antineoplastic Combined Chemotherapy Protocols*/administration & dosage, Humans ; Male ; Aged ; Double-Blind Method ; Middle Aged ; Administration, Intravenous ; Quality of Life ; Aged, 80 and over ; Neoplasm Metastasis

المؤلفون: Li M; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Smith BJ; Department of Cell Biology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Lee J; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Petr J; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Anders NM; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Present address: Takeda Pharmaceutical Company, San Diego, CA, USA., Wiseman R; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Rudek MA; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Division of Clinical Pharmacology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ambinder RF; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. rambind1@jhmi.edu., Desai PJ; Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. pdesai@jhmi.edu.

المصدر: Infectious agents and cancer [Infect Agent Cancer] 2024 Mar 04; Vol. 19 (1), pp. 7. Date of Electronic Publication: 2024 Mar 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101276559 Publication Model: Electronic Cited Medium: Print ISSN: 1750-9378 (Print) Linking ISSN: 17509378 NLM ISO Abbreviation: Infect Agent Cancer Subsets: PubMed not MEDLINE

المؤلفون: Davis MT; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA., Anders NM; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA.; Takeda Pharmaceutical Company, San Diego, California, USA., Colevas AD; Division of Medical Oncology, Stanford Cancer Center, Stanford University, Stanford, California, USA., Messick TE; The Wistar Institute, Philadelphia, Pennsylvania, USA., Rudek MA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA.; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Division of Clinical Pharmacology, Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.

المصدر: Biomedical chromatography : BMC [Biomed Chromatogr] 2024 Feb; Vol. 38 (2), pp. e5775. Date of Electronic Publication: 2023 Nov 09.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 8610241 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1099-0801 (Electronic) Linking ISSN: 02693879 NLM ISO Abbreviation: Biomed Chromatogr Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/chemistry , Epstein-Barr Virus Nuclear Antigens*/chemistry , Epstein-Barr Virus Nuclear Antigens*/pharmacology, Humans ; Chromatography, High Pressure Liquid/methods ; Chromatography, Liquid/methods ; Epstein-Barr Virus Infections ; Herpesvirus 4, Human ; Reproducibility of Results ; Spectrometry, Mass, Electrospray Ionization/methods ; Tandem Mass Spectrometry/methods

المؤلفون: Hsueh HT; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Chou RT; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA., Rai U; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kolodziejski P; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Liyanage W; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pejavar J; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Mozzer A; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Davison C; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Appell MB; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA., Kim YC; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Leo KT; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Kwon H; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Sista M; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Anders NM; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Hemingway A; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Rompicharla SVK; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pitha I; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Zack DJ; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Departments of Neuroscience, Molecular Biology and Genetics, and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hanes J; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Cummings MP; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA., Ensign LM; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA. Electronic address: lensign@jhmi.edu.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2023 Oct; Vol. 362, pp. 371-380. Date of Electronic Publication: 2023 Sep 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

المؤلفون: Kagan AB; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Garrison DA; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Anders NM; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA., Webster JA; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA., Baker SD; Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, Ohio, USA., Yegnasubramanian S; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA., Rudek MA; Department of Oncology, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; Department of Medicine, School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, Maryland, USA.

المصدر: Clinical and translational science [Clin Transl Sci] 2023 Aug; Vol. 16 (8), pp. 1309-1322. Date of Electronic Publication: 2023 Jun 21.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Azacitidine*/therapeutic use , Azacitidine*/pharmacology , Leukemia, Myeloid, Acute*/drug therapy, Humans ; Decitabine/therapeutic use ; Enzyme Inhibitors/pharmacology ; Enzyme Inhibitors/therapeutic use ; DNA Methylation ; DNA ; Methyltransferases

المؤلفون: Zhang J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China., Sharma D; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Dinabandhu A; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; Department of Oncology and Diagnostic Sciences, School of Dentistry, Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland, USA., Sanchez J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Applewhite B; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Jee K; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Deshpande M; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Flores-Bellver M; CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado School of Medicine, Aurora, Colorado, USA., Hu MW; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Guo C; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Salman S; Armstrong Oxygen Biology Research Center; Vascular Program, Institute for Cell Engineering; Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Hwang Y; Armstrong Oxygen Biology Research Center; Vascular Program, Institute for Cell Engineering; Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Anders NM; The Sidney Kimmel Comprehensive Cancer Center, Department of Oncology and the Division of Clinical Pharmacology at the School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Rudek MA; The Sidney Kimmel Comprehensive Cancer Center, Department of Oncology and the Division of Clinical Pharmacology at the School of Medicine, Johns Hopkins University, Baltimore, Maryland, USA., Qian J; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Canto-Soler MV; CellSight Ocular Stem Cell and Regeneration Research Program, Department of Ophthalmology, Sue Anschutz-Rodgers Eye Center, University of Colorado School of Medicine, Aurora, Colorado, USA., Semenza GL; Armstrong Oxygen Biology Research Center; Vascular Program, Institute for Cell Engineering; Departments of Pediatrics, Medicine, Oncology, Radiation Oncology, Biological Chemistry, and Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Montaner S; Department of Oncology and Diagnostic Sciences, School of Dentistry, Greenebaum Comprehensive Cancer Center, University of Maryland, Baltimore, Maryland, USA., Sodhi A; Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2023 Jul 03; Vol. 133 (13). Date of Electronic Publication: 2023 Jul 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Experimental*/metabolism , Retinal Neovascularization*/metabolism , Diabetic Retinopathy*/drug therapy , Diabetic Retinopathy*/genetics , Diabetic Retinopathy*/metabolism, Humans ; Mice ; Animals ; Acriflavine/metabolism ; Acriflavine/pharmacology ; Acriflavine/therapeutic use ; Retina/metabolism ; Hypoxia/metabolism ; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism

المؤلفون: Kagan AB; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA., Moses BS; Departments of Pediatrics and Physiology, School of Medicine, Center for Stem Cell Biology and Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, BRB14-021, 655 W Baltimore St, Baltimore, MD, 21201, USA.; Keros Therapeutics, Inc., Lexington, MA, USA., Lapidus R; Department of Medicine, School of Medicine, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, MD, USA., Mott BT; Department of Neurosurgery, Wake Forest Baptist Health, Winston-Salem, NC, USA., Rai G; Department of Pre-clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD, USA., Anders NM; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA.; Takeda Pharmaceutical Company, San Diego, CA, USA., Hoag SW; School of Pharmacy, University of Maryland, Baltimore, MD, USA., Rudek MA; Department of Medicine, Division of Clinical Pharmacology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. mrudek2@jhmi.edu.; Department of Oncology, School of Medicine, The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University, 1650 Orleans Street, CRB1 Room 1M52, Baltimore, MD, 21231-1000, USA. mrudek2@jhmi.edu., Civin CI; Departments of Pediatrics and Physiology, School of Medicine, Center for Stem Cell Biology and Regenerative Medicine, Marlene and Stewart Greenebaum Comprehensive Cancer Center, University of Maryland, BRB14-021, 655 W Baltimore St, Baltimore, MD, 21201, USA. Ccivin@som.umaryland.edu.

المصدر: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2023 Jul; Vol. 92 (1), pp. 39-50. Date of Electronic Publication: 2023 May 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Antimalarials*/pharmacology , Artemisinins*/pharmacology , Leukemia, Myeloid, Acute*/drug therapy, Humans ; Carbon/therapeutic use ; Sorafenib/therapeutic use

المؤلفون: Hsueh HT; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Chou RT; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA., Rai U; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Liyanage W; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kim YC; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Appell MB; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA., Pejavar J; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Leo KT; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA., Davison C; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Kolodziejski P; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Mozzer A; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Kwon H; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA., Sista M; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA., Anders NM; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Hemingway A; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Rompicharla SVK; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Edwards M; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Pitha I; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Hanes J; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA., Cummings MP; Center for Bioinformatics and Computational Biology, University of Maryland, College Park, College Park, MD, USA. mcummin1@umd.edu., Ensign LM; Center for Nanomedicine at the Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA. lensign@jhmi.edu.; Department of Chemical & Biomolecular Engineering, Johns Hopkins University, Baltimore, MD, USA. lensign@jhmi.edu.; Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. lensign@jhmi.edu.; Department of Pharmacology and Molecular Sciences, Johns Hopkins University, Baltimore, MD, USA. lensign@jhmi.edu.; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA. lensign@jhmi.edu.; The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, Baltimore, MD, USA. lensign@jhmi.edu.

المصدر: Nature communications [Nat Commun] 2023 May 02; Vol. 14 (1), pp. 2509. Date of Electronic Publication: 2023 May 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Melanins* , Drug Delivery Systems*, Animals ; Rabbits ; Brimonidine Tartrate ; Peptides ; Machine Learning

المؤلفون: Lee JL; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Zhang C; Department of Oncology, Division of Cancer Chemical and Structural Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Westbrook R; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Gabrawy MM; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Nidadavolu L; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Yang H; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Marx R; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Wu Y; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Anders NM; Department of Oncology, Division of Cancer Chemical and Structural Biology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.; The Johns Hopkins Analytical Pharmacology Core Laboratory, Clinical Pharmacology, Baltimore, MD, USA., Ma L; Department of Geriatrics, Xuanwu Hospital, Capital Medical University, China National Clinical Research Center for Geriatric Disorders, Beijing, China., Bichara MD; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Kwak MJ; Department of Internal Medicine, Division of Geriatric and Palliative Medicine, McGovern Medical School, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Buta B; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Khadeer M; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Yenokyan G; Johns Hopkins Biostatistics Center, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, USA., Tian J; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Xue QL; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Siragy HM; Department of Medicine, Division of Endocrine and Metabolism, University of Virginia, Charlottesville, Virginia, USA., Carey RM; Department of Medicine, Division of Endocrine and Metabolism, University of Virginia, Charlottesville, Virginia, USA., de Cabo R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Moaddel R; Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Rudek MA; The Johns Hopkins Analytical Pharmacology Core Laboratory, Clinical Pharmacology, Baltimore, MD, USA.; Department of Medicine, Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Le A; The Johns Hopkins Analytical Pharmacology Core Laboratory, Clinical Pharmacology, Baltimore, MD, USA.; Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Walston JD; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA., Abadir PM; Department of Medicine, Division of Geriatric Medicine and Gerontology, The Johns Hopkins University School of Medicine , Baltimore, Maryland, USA.

المصدر: The journals of gerontology. Series A, Biological sciences and medical sciences [J Gerontol A Biol Sci Med Sci] 2022 Dec 29; Vol. 77 (12), pp. 2356-2366.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: published on behalf of the Gerontological Society of America by Oxford University Press Country of Publication: United States NLM ID: 9502837 Publication Model: Print Cited Medium: Internet ISSN: 1758-535X (Electronic) Linking ISSN: 10795006 NLM ISO Abbreviation: J Gerontol A Biol Sci Med Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antihypertensive Agents*/administration & dosage , Antihypertensive Agents*/blood , Antihypertensive Agents*/pharmacokinetics , Frailty*/blood , Frailty*/drug therapy , Losartan*/administration & dosage , Losartan*/blood , Losartan*/pharmacokinetics , Physical Fitness*, Angiotensin Receptor Antagonists ; Imidazoles/metabolism ; Imidazoles/pharmacology ; Pilot Projects ; Tetrazoles/metabolism ; Tetrazoles/pharmacology ; Humans ; Aged