-
1دورية أكاديمية
المؤلفون: Andreano KJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Baker JG; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Park S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Safi R; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Artham S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Oesterreich S; Department of Pharmacology and Chemical Biology, University of Pittsburgh, Pittsburgh, Pennsylvania.; Womens Cancer Research Center, University of Pittsburgh Cancer Institute and Magee-Women Research Institute, Pittsburgh, Pennsylvania., Jeselsohn R; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Brown M; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Sammons S; Department of Medical Oncology, Duke Cancer Institute, Duke University, Durham, North Carolina., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Chang CY; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina. donald.mcdonnell@duke.edu.
المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2020 Jul; Vol. 19 (7), pp. 1395-1405. Date of Electronic Publication: 2020 May 07.
نوع المنشور: Journal Article; Research Support, N.I.H., Extramural
بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE
مواضيع طبية MeSH: Mutation*, Antineoplastic Agents, Hormonal/*pharmacology , Breast Neoplasms/*drug therapy , Estrogen Receptor alpha/*genetics , Estrogen Receptor alpha/*metabolism , Selective Estrogen Receptor Modulators/*pharmacology, Breast Neoplasms/genetics ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Female ; Humans ; Ligands ; Protein Binding ; Tumor Cells, Cultured
-
2دورية أكاديمية
المؤلفون: Andreano KJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Baker JG; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Desautels TK; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Baldi R; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Chao CA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Heetderks KA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Bae Y; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA., Xiong R; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL, 60612, USA., Tonetti DA; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL, 60612, USA., Gutgesell LM; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL, 60612, USA., Zhao J; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL, 60612, USA., Sorrentino JA; G1 Therapeutics, Inc, 700 Park Offices Drive, Suite 200, Research Triangle Park, NC, 27709, USA., Thompson DA; G1 Therapeutics, Inc, 700 Park Offices Drive, Suite 200, Research Triangle Park, NC, 27709, USA., Bisi JE; G1 Therapeutics, Inc, 700 Park Offices Drive, Suite 200, Research Triangle Park, NC, 27709, USA., Strum JC; G1 Therapeutics, Inc, 700 Park Offices Drive, Suite 200, Research Triangle Park, NC, 27709, USA., Thatcher GRJ; Department of Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street (M/C 781), Chicago, IL, 60612, USA., Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, 308 Research Drive, Durham, NC, 27710, USA. jdn001@duke.edu.
المصدر: Breast cancer research and treatment [Breast Cancer Res Treat] 2020 Apr; Vol. 180 (3), pp. 635-646. Date of Electronic Publication: 2020 Mar 04.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
مواضيع طبية MeSH: Antibodies, Monoclonal, Humanized/*pharmacology , Breast Neoplasms/*drug therapy , Cyclin-Dependent Kinase 4/*antagonists & inhibitors , Cyclin-Dependent Kinase 6/*antagonists & inhibitors , HIV Antibodies/*pharmacology , Neoplasms, Hormone-Dependent/*drug therapy , Selective Estrogen Receptor Modulators/*pharmacology, Animals ; Antineoplastic Combined Chemotherapy Protocols/pharmacology ; Apoptosis/drug effects ; Breast Neoplasms/metabolism ; Breast Neoplasms/pathology ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm ; Estrogen Antagonists/pharmacology ; Female ; Humans ; Mice ; Neoplasms, Hormone-Dependent/metabolism ; Neoplasms, Hormone-Dependent/pathology ; Protein Kinase Inhibitors/pharmacology ; Receptors, Estrogen/metabolism ; Tamoxifen/pharmacology ; Tumor Cells, Cultured ; Xenograft Model Antitumor Assays
-
3دورية أكاديمية
المؤلفون: Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Yllanes AP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Chao CA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Bae Y; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Andreano KJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Desautels TK; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Heetderks KA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Blitzer JT; Potrero Hill Therapeutics, San Francisco, CA, 94110, USA., Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA. donald.mcdonnell@duke.edu.
المصدر: Breast cancer research and treatment [Breast Cancer Res Treat] 2020 Feb; Vol. 179 (3), pp. 769.
نوع المنشور: Journal Article; Published Erratum
بيانات الدورية: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: PubMed not MEDLINE; MEDLINE
-
4دورية أكاديمية
المؤلفون: Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Yllanes AP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Chao CA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Bae Y; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Andreano KJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Desautels TK; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Heetderks KA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., Blitzer JT; Potrero Hill Therapeutics, San Francisco, CA, 94110, USA., Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Box 3813, Durham, NC, 27710, USA. donald.mcdonnell@duke.edu.
المصدر: Breast cancer research and treatment [Breast Cancer Res Treat] 2020 Jan; Vol. 179 (1), pp. 67-77. Date of Electronic Publication: 2019 Sep 27.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Kluwer Academic Country of Publication: Netherlands NLM ID: 8111104 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7217 (Electronic) Linking ISSN: 01676806 NLM ISO Abbreviation: Breast Cancer Res Treat Subsets: MEDLINE
مواضيع طبية MeSH: Antineoplastic Agents, Hormonal/*pharmacokinetics , Breast Neoplasms/*drug therapy , Estrogen Receptor Antagonists/*pharmacokinetics , Fulvestrant/*pharmacokinetics, Administration, Oral ; Animals ; Antineoplastic Agents, Hormonal/administration & dosage ; Dose-Response Relationship, Drug ; Estrogen Receptor Antagonists/administration & dosage ; Estrogen Receptor alpha/antagonists & inhibitors ; Female ; Fulvestrant/administration & dosage ; Mice ; Xenograft Model Antitumor Assays
-
5دورية أكاديمية
المؤلفون: Gaillard SL; Duke University Medical Center, Durham, NC, United States of America; Johns Hopkins Sidney Kimmel Cancer Center, Baltimore, MD, United States of America. Electronic address: stephanie.gaillard@jhmi.edu., Andreano KJ; Duke University Medical Center, Durham, NC, United States of America., Gay LM; Foundation Medicine, Inc., Cambridge, MA, United States of America., Steiner M; Duke University Medical Center, Durham, NC, United States of America., Jorgensen MS; Mayo Clinic, Jacksonville, FL, United States of America., Davidson BA; Duke University Medical Center, Durham, NC, United States of America., Havrilesky LJ; Duke University Medical Center, Durham, NC, United States of America., Alvarez Secord A; Duke University Medical Center, Durham, NC, United States of America., Valea FA; Duke University Medical Center, Durham, NC, United States of America., Colon-Otero G; Mayo Clinic, Jacksonville, FL, United States of America., Zajchowski DA; The Clearity Foundation, San Diego, CA, United States of America., Chang CY; Duke University Medical Center, Durham, NC, United States of America., McDonnell DP; Duke University Medical Center, Durham, NC, United States of America., Berchuck A; Duke University Medical Center, Durham, NC, United States of America., Elvin JA; Duke University Medical Center, Durham, NC, United States of America.
المصدر: Gynecologic oncology [Gynecol Oncol] 2019 Jul; Vol. 154 (1), pp. 199-206. Date of Electronic Publication: 2019 Apr 13.
نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't
بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0365304 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-6859 (Electronic) Linking ISSN: 00908258 NLM ISO Abbreviation: Gynecol Oncol
مواضيع طبية MeSH: Aromatase Inhibitors/*administration & dosage , Estrogen Receptor alpha/*genetics , Genital Neoplasms, Female/*drug therapy , Genital Neoplasms, Female/*genetics , Selective Estrogen Receptor Modulators/*administration & dosage, Adult ; Aromatase Inhibitors/pharmacology ; DNA, Neoplasm/genetics ; Drug Resistance, Neoplasm ; Female ; Humans ; Middle Aged ; Molecular Targeted Therapy ; Mutation ; Selective Estrogen Receptor Modulators/pharmacology ; Transcription, Genetic/drug effects ; Transcriptome ; Treatment Outcome ; Young Adult
-
6دورية أكاديمية
المؤلفون: Norris JD; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Ellison SJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Baker JG; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Stagg DB; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Wardell SE; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Park S; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Alley HM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Baldi RM; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Yllanes A; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Andreano KJ; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Stice JP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Lawrence SA; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA., Eisner JR; Innocrin Pharmaceuticals Inc., Durham, North Carolina, USA., Price DK; Genitourinary Malignancies Branch, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA., Moore WR; Innocrin Pharmaceuticals Inc., Durham, North Carolina, USA., Figg WD; Genitourinary Malignancies Branch, National Cancer Institute (NCI), NIH, Bethesda, Maryland, USA., McDonnell DP; Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, USA.
المصدر: The Journal of clinical investigation [J Clin Invest] 2017 Jun 01; Vol. 127 (6), pp. 2326-2338. Date of Electronic Publication: 2017 May 02.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE
مواضيع طبية MeSH: Androgen Receptor Antagonists/*pharmacology , Antineoplastic Agents, Hormonal/*pharmacology , Prostatic Neoplasms, Castration-Resistant/*drug therapy , Steroid 17-alpha-Hydroxylase/*antagonists & inhibitors, Active Transport, Cell Nucleus ; Animals ; Benzamides ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm ; Drug Synergism ; HEK293 Cells ; Humans ; Inhibitory Concentration 50 ; Male ; Metribolone/pharmacology ; Mice, Inbred NOD ; Mice, SCID ; Nitriles ; Phenylthiohydantoin/analogs & derivatives ; Phenylthiohydantoin/pharmacology ; Protein Binding ; Receptors, Androgen/metabolism ; Steroid 17-alpha-Hydroxylase/metabolism ; Testosterone/pharmacology ; Transcriptional Activation/drug effects ; Xenograft Model Antitumor Assays