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1دورية أكاديمية
المؤلفون: Irene Hallyburton, Raffaella Grimaldi, Andrew Woodland, Beatriz Baragaña, Torsten Luksch, Daniel Spinks, Daniel James, Didier Leroy, David Waterson, Alan H. Fairlamb, Paul G. Wyatt, Ian H. Gilbert, Julie A. Frearson
المصدر: Malaria Journal, Vol 16, Iss 1, Pp 1-11 (2017)
مصطلحات موضوعية: Arctic medicine. Tropical medicine, RC955-962, Infectious and parasitic diseases, RC109-216
وصف الملف: electronic resource
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المؤلفون: Lauren A. Webster, Mark Bell, Andrew Woodland
المصدر: Journal of Investigative Dermatology. 139:2252-2257.e1
مصطلحات موضوعية: Risk, 0301 basic medicine, Drug, medicine.medical_specialty, Computer science, media_common.quotation_subject, Drug Evaluation, Preclinical, Dermatology, Biochemistry, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Animals, Humans, Molecular Biology, media_common, Simple (philosophy), Clinical Trials as Topic, United States Food and Drug Administration, Drug discovery, Product profile, Drug Repositioning, Cell Biology, United States, Drug repositioning, 030104 developmental biology, Drug development, 030220 oncology & carcinogenesis, Costs and Cost Analysis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5144c1dea38f2433573938dded92de0
https://doi.org/10.1016/j.jid.2019.07.699 -
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المؤلفون: Mark, Bell, David, Foley, Claire, Naylor, Colin, Robinson, Jennifer, Riley, Ola, Epemolu, Paul, Scullion, Yoko, Shishikura, Elad, Katz, W H Irwin, McLean, Paul, Wyatt, Kevin D, Read, Andrew, Woodland
المصدر: Bioorganic & Medicinal Chemistry Letters
مصطلحات موضوعية: Chromatography, Reverse-Phase, Aryldialkylphosphatase, Administration, Topical, Soft-drug, Plasma stability, Esterases, Article, Receptors, Lysosphingolipid, Structure-Activity Relationship, Thiazoles, Solubility, Topical, Drug Discovery, Humans, Psoriasis, Sphingosine-1-Phosphate Receptors, Chromatography, High Pressure Liquid, ComputingMethodologies_COMPUTERGRAPHICS, Skin, S1PR1
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المؤلفون: Andrea Pawallek, Stuart McElroy, Timur Samatov, Lee Mitchell, Andrew Woodland, Ursula Ryder, David Gray, Reinhard Lührmann, Angus I. Lamond
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: RNA Splicing, Drug Evaluation, Preclinical, Biochemistry, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, RNA Precursors, Humans, RNA, Messenger, Molecular Biology, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Madrasin, Cell Biology, High Throughput Screening, High-Throughput Screening Assays, 3. Good health, HEK293 Cells, Spliceosome, DDD00107587, 030220 oncology & carcinogenesis, Quinazolines, RNA, Small Molecule, Additions and Corrections, HeLa Cells
وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.spreadsheetml.sheet
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3a380045da0527d6a956470aca343f
http://europepmc.org/articles/PMC4263873 -
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المؤلفون: Andrew Woodland, Torsten Luksch, Julie A. Frearson, Kayode K. Ojo, Paul G. Wyatt, Ian H. Gilbert, Ruth Brenk, Laura A. T. Cleghorn, Wesley C. Van Voorhis, Raffaella Grimaldi
المصدر: Chemmedchem
مصطلحات موضوعية: Models, Molecular, Trypanosoma brucei brucei, Biology, Trypanosoma brucei, Biochemistry, GSK3, Cell Line, Glycogen Synthase Kinase 3, Structure-Activity Relationship, 03 medical and health sciences, Parasitic Sensitivity Tests, medicinal chemistry, parasitic diseases, Drug Discovery, medicine, Humans, Structure–activity relationship, African trypanosomiasis, General Pharmacology, Toxicology and Pharmaceutics, Protein kinase A, Protein Kinase Inhibitors, Cell Proliferation, 030304 developmental biology, Pharmacology, protein kinases, 0303 health sciences, Dose-Response Relationship, Drug, Molecular Structure, 030306 microbiology, Drug discovery, Kinase, Organic Chemistry, Full Papers, medicine.disease, biology.organism_classification, Trypanocidal Agents, In vitro, 3. Good health, Molecular Medicine, Pharmacophore, antiprotozoal agents
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المؤلفون: Iain T. Collie, Julie A. Frearson, Paul G. Wyatt, Laura A. T. Cleghorn, Ruth Brenk, Chidochangu P. Mpamhanga, Roderick G. Walker, Torsten Luksch, Jeremy C. Mottram, Andrew Woodland, Neil R. Norcross, Ian H. Gilbert, Leah S. Torrie
المصدر: Chemmedchem
مصطلحات موضوعية: Drug Evaluation, Preclinical, Protozoan Proteins, cyclin-dependent cdc2-related kinases, Trypanosoma brucei, Biochemistry, Structure-Activity Relationship, Cyclin-dependent kinase, CDC2 Protein Kinase, Drug Discovery, Humans, Urea, Computer Simulation, General Pharmacology, Toxicology and Pharmaceutics, Protein kinase A, Protein Kinase Inhibitors, leishmaniasis, Leishmania, Pharmacology, Cyclin-dependent kinase 1, Binding Sites, biology, Kinase, ureas, Organic Chemistry, Cyclin-dependent kinase 2, Full Papers, biology.organism_classification, Protein Structure, Tertiary, CRK3, Pyrimidines, triazolopyridines, biology.protein, Pyrazoles, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2202f6601d8578d3a2bae1b2198e8018
https://doi.org/10.1002/cmdc.201100344 -
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المؤلفون: Nicola J, Gardner, Peter J, Gillespie, Jamie T, Carrington, Emma J, Shanks, Stuart P, McElroy, Emma J, Haagensen, Julie A, Frearson, Andrew, Woodland, J Julian, Blow
المصدر: Cell Chemical Biology
مصطلحات موضوعية: DNA Replication, Minichromosome Maintenance Proteins, replication licensing, Xenopus, Origin Recognition Complex, Nuclear Proteins, Cell Cycle Proteins, Replication Origin, DNA, Xenopus Proteins, Chromatin, Article, Thiazoles, cancer therapeutics, Adenosine Triphosphate, Allosteric Regulation, ORC, Cell Line, Tumor, Quinolines, Animals, Humans, Amines, MCM2–7
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المؤلفون: Alan H. Fairlamb, Victoria Smith, Daniel Spinks, Julie A. Frearson, Ruth Brenk, Suzanne Norval, Andrew Woodland, Paul G. Wyatt, Iain T. Collie, Ian H. Gilbert, Laura A. T. Cleghorn, Kevin D. Read, N. Yi Mok, Irene Hallyburton
المصدر: Chemmedchem
مصطلحات موضوعية: Models, Molecular, Narcotic antagonists, human African trypanosomiasis, Narcotic Antagonists, Trypanosoma brucei brucei, Antiprotozoal Agents, Trypanosoma brucei, Pharmacology, Biochemistry, Structure-Activity Relationship, Pharmacokinetics, Opioid Agonist, medicinal chemistry, parasitic diseases, Drug Discovery, Humans, Structure–activity relationship, General Pharmacology, Toxicology and Pharmaceutics, EC50, Full Paper, biology, Organic Chemistry, 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer, U50488, biology.organism_classification, Trypanosomiasis, African, Receptors, Opioid, Molecular Medicine
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المؤلفون: Andrew, Woodland, Stephen, Thompson, Laura A T, Cleghorn, Neil, Norcross, Manu, De Rycker, Raffaella, Grimaldi, Irene, Hallyburton, Bhavya, Rao, Suzanne, Norval, Laste, Stojanovski, Reto, Brun, Marcel, Kaiser, Julie A, Frearson, David W, Gray, Paul G, Wyatt, Kevin D, Read, Ian H, Gilbert
المصدر: Chemmedchem
مصطلحات موضوعية: Trypanosoma brucei rhodesiense, Dose-Response Relationship, Drug, Molecular Structure, Full Papers, Cell Line, Small Molecule Libraries, Structure-Activity Relationship, Phenotype, cidal, kinases, static, Parasitic Sensitivity Tests, phenotypic, Drug Discovery, Humans, Trypanosoma brucei, Protein Kinase Inhibitors, Protein Kinases
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المؤلفون: Beatriz, Baragaña, Irene, Hallyburton, Marcus C S, Lee, Neil R, Norcross, Raffaella, Grimaldi, Thomas D, Otto, William R, Proto, Andrew M, Blagborough, Stephan, Meister, Grennady, Wirjanata, Andrea, Ruecker, Leanna M, Upton, Tara S, Abraham, Mariana J, Almeida, Anupam, Pradhan, Achim, Porzelle, Torsten, Luksch, María Santos, Martínez, Judith M, Bolscher, Andrew, Woodland, Suzanne, Norval, Fabio, Zuccotto, John, Thomas, Frederick, Simeons, Laste, Stojanovski, Maria, Osuna-Cabello, Paddy M, Brock, Tom S, Churcher, Katarzyna A, Sala, Sara E, Zakutansky, María Belén, Jiménez-Díaz, Laura Maria, Sanz, Jennifer, Riley, Rajshekhar, Basak, Michael, Campbell, Vicky M, Avery, Robert W, Sauerwein, Koen J, Dechering, Rintis, Noviyanti, Brice, Campo, Julie A, Frearson, Iñigo, Angulo-Barturen, Santiago, Ferrer-Bazaga, Francisco Javier, Gamo, Paul G, Wyatt, Didier, Leroy, Peter, Siegl, Michael J, Delves, Dennis E, Kyle, Sergio, Wittlin, Jutta, Marfurt, Ric N, Price, Robert E, Sinden, Elizabeth A, Winzeler, Susan A, Charman, Lidiya, Bebrevska, David W, Gray, Simon, Campbell, Alan H, Fairlamb, Paul A, Willis, Julian C, Rayner, David A, Fidock, Kevin D, Read, Ian H, Gilbert
المساهمون: Medicines for Malaria Venture, Medical Research Council (MRC)
المصدر: Nature, 522, 315-20
Nature, 522, 7556, pp. 315-20
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madridمصطلحات موضوعية: Male, Models, Molecular, Plasmodium, TRANSMISSION, General Science & Technology, Plasmodium berghei, Plasmodium vivax, Plasmodium falciparum, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Drug resistance, Computational biology, MALARIA CONTROL, Antimalarials, GAMETOCYTES, Peptide Elongation Factor 2, ELONGATION-FACTOR 2, MD Multidisciplinary, Drug Discovery, Animals, Antimalarial Agent, VIVAX, Life Cycle Stages, Science & Technology, Multidisciplinary, PLASMODIUM-FALCIPARUM, IDENTIFICATION, biology, Drug discovery, Chemoprotection, biology.organism_classification, 3. Good health, Malaria, Multidisciplinary Sciences, Drug development, Gene Expression Regulation, Liver, NEXT-GENERATION, Protein Biosynthesis, Quinolines, Science & Technology - Other Topics, POPULATIONS, Female
وصف الملف: application/pdf
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