المؤلفون: Susana S. Correia, Guang Liu, Sarah Jacobson, Sylvie G. Bernier, Jenny V. Tobin, Chad D. Schwartzkopf, Emily Atwater, Elisabeth Lonie, Sam Rivers, Andrew Carvalho, Peter Germano, Kim Tang, Rajesh R. Iyengar, Mark G. Currie, John R. Hadcock, Christopher J. Winrow, Juli E. Jones

المصدر: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)

مصطلحات موضوعية: Soluble guanylate cyclase, sGC, cGMP, Nitric oxide, CREB, Microglia, Neurology. Diseases of the nervous system, RC346-429

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1742-2094

URL الوصول: https://doaj.org/article/b9dc10997df94c7186de03737efe4dd1

المؤلفون: Susana S. Correia, Rajesh R. Iyengar, Peter Germano, Kim Tang, Sylvie G. Bernier, Chad D. Schwartzkopf, Jenny Tobin, Thomas W.-H. Lee, Guang Liu, Sarah Jacobson, Andrew Carvalho, Glen R. Rennie, Joon Jung, Paul A. Renhowe, Elisabeth Lonie, Christopher J. Winrow, John R. Hadcock, Juli E. Jones, Mark G. Currie

المصدر: Frontiers in Pharmacology, Vol 12 (2021)

مصطلحات موضوعية: cGMP (cyclic GMP), nitric oxide, soluble guanylate cyclase (sGC), neurodegeneration, neuroprotection, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fphar.2021.656561/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/77b2ed6c8b9c4de4b87274d76d632880

المؤلفون: Daniel P. Zimmer, Courtney M. Shea, Jenny V. Tobin, Boris Tchernychev, Peter Germano, Kristie Sykes, Ali R. Banijamali, Sarah Jacobson, Sylvie G. Bernier, Renee Sarno, Andrew Carvalho, Yueh-tyng Chien, Regina Graul, Emmanuel S. Buys, Juli E. Jones, James D. Wakefield, Gavrielle M. Price, Jennifer G. Chickering, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer

المصدر: Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: olinciguat, soluble guanylate cyclase, cGMP, nitric oxide, cardioprotective, renoprotective, Therapeutics. Pharmacology, RM1-950

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/article/10.3389/fphar.2020.00419/full; https://doaj.org/toc/1663-9812

URL الوصول: https://doaj.org/article/e994be112c3a40db87031271143e9556

المؤلفون: Sylvie G. Bernier, Peter Germano, Christopher J. Winrow, Chad D. Schwartzkopf, Susana S. Correia, Kim Tang, Juli E. Jones, Sam Rivers, Elisabeth Lonie, Guang Liu, Sarah Jacobson, Andrew Carvalho, Jenny Tobin, John R. Hadcock, Emily Atwater, Rajesh R. Iyengar, Mark G. Currie

المصدر: Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-13 (2021)
Journal of Neuroinflammation

مصطلحات موضوعية: Central Nervous System, Male, sGC, Immunology, Anti-Inflammatory Agents, Pharmacology, Neuroprotection, Rats, Sprague-Dawley, Mice, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Soluble Guanylyl Cyclase, Neuroinflammation, medicine, Animals, Humans, Soluble guanylate cyclase, Quinolinic acid, RC346-429, Cyclic GMP, Cells, Cultured, Neurons, Dose-Response Relationship, Drug, Glial fibrillary acidic protein, biology, Microglia, CREB, Research, General Neuroscience, HEK 293 cells, Nitric oxide, Rats, Mice, Inbred C57BL, cGMP, High-fat diet, HEK293 Cells, medicine.anatomical_structure, Neurology, chemistry, biology.protein, Tumor necrosis factor alpha, Neurology. Diseases of the nervous system, Inflammation Mediators, cGMP-dependent protein kinase, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::199a830a1937f260ccf762e3f641c144
https://doi.org/10.1186/s12974-021-02275-z

المؤلفون: Andrew Carvalho, Kim Tang, Christopher J. Winrow, John R. Hadcock, Sarah Jacobson, Jenny Tobin, Elisabeth Lonie, Sylvie G. Bernier, Thomas W.-H. Lee, Susana S. Correia, Rennie Glen Robert, Chad D. Schwartzkopf, Joon Jung, Peter Germano, Guang Liu, Juli E. Jones, Mark G. Currie, Paul Allan Renhowe, Rajesh R. Iyengar

المصدر: Frontiers in Pharmacology, Vol 12 (2021)
Frontiers in Pharmacology

مصطلحات موضوعية: 0301 basic medicine, medicine.drug_class, Inflammation, RM1-950, Pharmacology, Neuroprotection, Nitric oxide, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, nitric oxide, medicine, Pharmacology (medical), Donepezil, Cyclic guanosine monophosphate, Original Research, business.industry, Neurodegeneration, neurodegeneration, Long-term potentiation, cGMP (cyclic GMP), medicine.disease, Receptor antagonist, 030104 developmental biology, chemistry, neuroprotection, Therapeutics. Pharmacology, medicine.symptom, business, 030217 neurology & neurosurgery, soluble guanylate cyclase (sGC), medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f32016c7ebcec298b36c97328d53b8a4
https://www.frontiersin.org/articles/10.3389/fphar.2021.656561/full

المؤلفون: Jia Lei, Joon Jung, Sylvie G. Bernier, Joel D. Moore, Glen Rennie, Mermerian Ara, Nicholas Robert Perl, Thomas Wai-Ho Lee, Andrew Carvalho, Barden Timothy Claude, Peter Germano, Jenny Tobin, Colleen Hudson, Renee Deming, Rajesh R. Iyengar, Takashi Nakai, G-Yoon Jamie Im, Paul A. Renhowe, Daniel P. Zimmer, Elise Kim

المصدر: Bioorganicmedicinal chemistry letters. 40

مصطلحات موضوعية: Male, Models, Molecular, Carboxylic acid, Hypertension, Pulmonary, Vasodilator Agents, Clinical Biochemistry, Carboxylic Acids, Drug Evaluation, Preclinical, Pharmaceutical Science, Administration, Oral, Pharmacology, Nitric Oxide, Biochemistry, Nitric oxide, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Glucuronides, Soluble Guanylyl Cyclase, Drug Discovery, medicine, Animals, Humans, Molecular Biology, chemistry.chemical_classification, Dose-Response Relationship, Drug, Organic Chemistry, Soluble Guanylate Cyclase Stimulator, medicine.disease, Pulmonary hypertension, Bioavailability, Oxidative Stress, chemistry, Metabolome, Molecular Medicine, Signal transduction, Metabolic profile, Guanylate cyclase, Protein Binding, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee9de2bad2e2d41649c98451bf1e9a94
https://pubmed.ncbi.nlm.nih.gov/33662540

المؤلفون: Mark G. Currie, John R. Hadcock, Juli E. Jones, Andrew Carvalho, Chad D. Schwartzkopf

المصدر: Diabetes. 69

مصطلحات موضوعية: Drug, medicine.medical_specialty, Creatinine, business.industry, Endocrinology, Diabetes and Metabolism, media_common.quotation_subject, Urinary system, Cmax, Hemodynamics, Metabolism, chemistry.chemical_compound, Endocrinology, chemistry, Weight loss, Internal medicine, Internal Medicine, medicine, medicine.symptom, business, Thermogenesis, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0ba9de97f4ff65247388bb7f43837aa0
https://doi.org/10.2337/db20-124-lb

المؤلفون: Jenny Tobin, Albert T. Profy, Ali R. Banijamali, Mark G. Currie, James Wakefield, Jaime L. Masferrer, G. Todd Milne, Daniel P. Zimmer, Andrew Carvalho, Peter Germano, Barden Timothy Claude

المصدر: Pharmacology Research & Perspectives
Pharmacology Research & Perspectives, Vol 8, Iss 2, Pp n/a-n/a (2020)

مصطلحات موضوعية: Male, medicine.medical_specialty, sGC, Metabolite, praliciguat, Glucuronidation, Adipose tissue, RM1-950, 030226 pharmacology & pharmacy, Excretion, Rats, Sprague-Dawley, 03 medical and health sciences, chemistry.chemical_compound, Feces, 0302 clinical medicine, Soluble Guanylyl Cyclase, Pharmacokinetics, Oral administration, nitric oxide, Internal medicine, QWBA, medicine, Animals, Bile, Rats, Long-Evans, Tissue Distribution, General Pharmacology, Toxicology and Pharmaceutics, Original Articles, Bioavailability, cGMP, Endocrinology, Pyrimidines, Neurology, chemistry, 030220 oncology & carcinogenesis, Pyrazoles, Original Article, excretion, Therapeutics. Pharmacology, absorption, metabolism, pharmacokinetics, Drug metabolism, mass balance

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b3e4df24159164c127118e8e21c0b4
http://europepmc.org/articles/PMC7171252

المؤلفون: Sarah Jacobson, Jenny Tobin, Renee Sarno, Jaime L. Masferrer, Andrew Carvalho, Boris Tchernychev, Yueh-Tyng Chien, G. Todd Milne, Jennifer G. Chickering, Peter Germano, Ali R. Banijamali, Gavrielle M Price, Emmanuel S. Buys, James Wakefield, Regina Graul, Juli E. Jones, Courtney Shea, Sylvie G. Bernier, Daniel P. Zimmer, Kristie Sykes, Mark G. Currie

المصدر: Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)

مصطلحات موضوعية: 0301 basic medicine, soluble guanylate cyclase, Vascular smooth muscle, medicine.drug_mechanism_of_action, cardioprotective, Inflammation, Pharmacology, Nitric oxide, Diabetic nephropathy, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, nitric oxide, medicine, Distribution (pharmacology), vascular inflammation, Pharmacology (medical), Original Research, Cardioprotection, business.industry, lcsh:RM1-950, medicine.disease, cGMP, olinciguat, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, medicine.symptom, business, Phosphodiesterase 5 inhibitor, renoprotective

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::235faf214a0dad4f1fdd0e1ad72b1cd8
https://pubmed.ncbi.nlm.nih.gov/32322204

المؤلفون: Andrew Carvalho, Ali R. Banijamali, Alicja Borowik, Frank Scheffler, Deepa Karunakaran, Jonathan Steele, Julia Shanu-Wilson, Richard Phipps, Ravi Manohar, Liam Evans

المصدر: Drug Metabolism and Pharmacokinetics. 35:S25

مصطلحات موضوعية: Pharmacology, chemistry.chemical_compound, Biotransformation, Biochemistry, Chemistry, Metabolite, Pharmaceutical Science, Pharmacology (medical), Guanylate cyclase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::665b53ad7c8fa1ca0c262a47252cf155
https://doi.org/10.1016/j.dmpk.2020.04.011