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1
المؤلفون: Allen Ebens, Klara Totpal, Robert Kelley, Mark S. Dennis, Melissa R. Junttila, Justin M. Scheer, Bryan Irving, Andrew Polson, Christoph Spiess, Eric Stefanich, Gail Lewis Phillips, Elizabeth Luis, Judy Young, Guangmin Li, Mary Mathieu, Yijin Li, Bu-Er Wang, Diego Ellerman, Robyn Clark, Maria Hristopoulos, Jennifer Johnston, Ji Li, Teemu T. Junttila
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17567e5e1fe58bc9405924b89debd588
https://doi.org/10.1158/0008-5472.22403234.v1 -
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المؤلفون: Neelie Zacharias, Vladimir N. Podust, Kimberly K. Kajihara, Douglas Leipold, Geoffrey Del Rosario, Desiree Thayer, Emily Dong, Maciej Paluch, David Fischer, Kai Zheng, Corinna Lei, Jintang He, Carl Ng, Dian Su, Luna Liu, Shabkhaiz Masih, William Sawyer, Jeff Tinianow, Jan Marik, Victor Yip, Guangmin Li, Josefa Chuh, J. Hiroshi Morisaki, Summer Park, Bing Zheng, Hilda Hernandez-Barry, Kelly M. Loyet, Min Xu, Katherine R. Kozak, Gail Lewis Phillips, Ben-Quan Shen, Cong Wu, Keyang Xu, Shang-Fan Yu, Amrita Kamath, Rebecca K. Rowntree, Dorothea Reilly, Thomas Pillow, Andrew Polson, Volker Schellenberger, Wouter L. W. Hazenbos, Jack Sadowsky
المصدر: Chemical Science. 13:3147-3160
مصطلحات موضوعية: General Chemistry
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bce602efd8f14a1021c22dad6d1512
https://doi.org/10.1039/d1sc05243h -
3
المؤلفون: Kyu Hong, Peter S. Dragovich, Bing Zheng, Douglas D. Leipold, Thomas H. Pillow, Andrew Polson, Peter Yan, Shang-Fan Yu, Montserrat Carrasco-Triguero, Melissa Schutten, Geoffrey Del Rosario, Rebecca K. Rowntree, Fiona Zhong, Jack Sadowsky, Donna W. Lee, Helen Booler
المصدر: Molecular Cancer Therapeutics. 20:340-346
مصطلحات موضوعية: 0301 basic medicine, Oncology, Cancer Research, Antibody-drug conjugate, medicine.medical_specialty, business.industry, CD22, medicine.disease, Lymphoma, Polatuzumab vedotin, body regions, Clinical trial, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, 030220 oncology & carcinogenesis, Internal medicine, medicine, Microtubule Inhibitor, Hodgkin lymphoma, business, Pinatuzumab vedotin
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::05119968230e699eb33bb8cdb1d79112
https://doi.org/10.1158/1535-7163.mct-20-0046 -
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المؤلفون: Volker Schellenberger, David Fischer, Bing Zheng, Thomas H. Pillow, Amrita V. Kamath, Carl Ng, Jan Marik, Corinna Lei, Dorothea Reilly, Shabkhaiz Masih, Kelly M. Loyet, Vladimir N. Podust, Kimberly Kajihara, Maciej Paluch, Andrew Polson, Gail Dianne Phillips, Summer Park, Luna Liu, Morisaki John Hiroshi, Kai Zheng, Guangmin Li, Dian Su, Douglas D. Leipold, Josefa Chuh, Victor Yip, Emily Dong, Shang-Fan Yu, Wouter L. W. Hazenbos, Jack Sadowsky, Geoffrey Del Rosario, Rebecca K. Rowntree, Jeff N. Tinianow, Neelie Zacharias, Min Xu, William S. Sawyer, Katherine R. Kozak, Hilda Hernandez-Barry, Jintang He, Cong Wu, Keyang Xu, Ben-Quan Shen
مصطلحات موضوعية: body regions, Antibody-drug conjugate, Biochemistry, biology, Homogeneous, Chemistry, fungi, parasitic diseases, biology.protein, Antibody
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a7d05e7d54cc2ba403b546592bdee064
https://doi.org/10.21203/rs.3.rs-356231/v1 -
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المؤلفون: Melissa Schutten, Brandon Latifi, Ola Saad, Steven T Laing, Shabkhaiz Masih, Jintang He, Isabel Figueroa, Katherine R. Kozak, Douglas D. Leipold, Randall C. Dere, M. Violet Lee, Brian R. Vuillemenot, Andrew Polson, Keyang Xu, Ben-Quan Shen, Montserrat Carrasco-Triguero, Luna Liu, Dian Su, Victor Yip, Bing Zheng, Amrita V. Kamath
المصدر: mAbs
مصطلحات موضوعية: 0301 basic medicine, Antibody-drug conjugate, Immunoconjugates, Metabolic Clearance Rate, Immunology, acute myeloid leukemia, Pharmacology, Benzodiazepines, Mice, 03 medical and health sciences, Species Specificity, Pharmacokinetics, Report, hemic and lymphatic diseases, Preclinical pharmacokinetics, Animals, Humans, Immunology and Allergy, Medicine, receptor occupancy, Lectins, C-Type, Pyrroles, Receptor, neoplasms, business.industry, PBD dimer, Antibodies, Monoclonal, Treatment options, Myeloid leukemia, Rats, Macaca fascicularis, 030104 developmental biology, Leukemia, Myeloid, Area Under Curve, Immunoglobulin G, Receptors, Mitogen, Pharmacodynamics, Acute Disease, CLL-1, business, pharmacokinetics, Conjugate
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المؤلفون: Chris Frantz, Keyang Xu, Katherine R. Kozak, Thomas H. Pillow, Zijin Xu, Geoffrey Del Rosario, Pragya Adhikari, Douglas D. Leipold, Andrew Polson, Jinhua Chen, Shang-Fan Yu, Mary Ann T. Go, Breanna S. Vollmar, Josefa dela Cruz-Chuh, Peter S. Dragovich, Amrita V. Kamath, Hans Erickson, Fiona Zhong, John S. Wai, Carl Ng, Melissa Schutten
المصدر: Molecular cancer therapeutics. 20(6)
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunoconjugates, Gemtuzumab ozogamicin, CD33, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Calicheamicin, medicine, Animals, Humans, Inotuzumab ozogamicin, Antibiotics, Antineoplastic, CD22, Myeloid leukemia, body regions, Disease Models, Animal, 030104 developmental biology, Oncology, chemistry, Calicheamicins, 030220 oncology & carcinogenesis, Cancer research, Linker, medicine.drug, Conjugate
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ea774d110d9f3fb9ee986f88f4881a
https://pubmed.ncbi.nlm.nih.gov/33722856 -
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المؤلفون: Lu Yang, Wing C. Chan, Teresa Sadras, Zhengshan Chen, Hassan Jumaa, Gauri Deb, Xin Yang, Jae-Woong Lee, Markus Müschen, Hans Clevers, Andrew Polson, Maurizio Mangolini, Joo Y. Song, Lai N. Chan, Janet Winchester, Kohei Kume, Gang Xiao, Huimin Geng, Mark E. Robinson, Shai Izraeli, Kadriye Nehir Cosgun
مصطلحات موضوعية: 0303 health sciences, Cell type, LGR5, Biology, medicine.disease, Cell biology, 03 medical and health sciences, Haematopoiesis, Leukemia, 0302 clinical medicine, 030220 oncology & carcinogenesis, Catenin, Cancer cell, medicine, Stem cell, Transcription factor, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181a35dae1297bfde44a1bd65568d7a7
https://doi.org/10.1101/2020.03.12.989277 -
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المؤلفون: Melissa Schutten, Keyang Xu, Bing Zheng, Aimee Fourie-O'Donohue, Hong Wang, Katherine R. Kozak, Steve R. Leong, Amrita V. Kamath, Andrew Polson, Isabel Figueroa, Montserrat Triguero-Carrasco, Doug Leipold
المصدر: mAbs. 10:738-750
مصطلحات موضوعية: Antibody-drug conjugate, Immunoconjugates, Sialic Acid Binding Ig-like Lectin 3, Immunology, CD33, Pharmacology, Models, Biological, 030226 pharmacology & pharmacy, 03 medical and health sciences, 0302 clinical medicine, Species Specificity, Pharmacokinetics, Cell Line, Tumor, Animals, Humans, Immunology and Allergy, Prospective Studies, Receptor, biology, Chemistry, Antibodies, Monoclonal, Pre-clinical development, Macaca fascicularis, HEK293 Cells, Tolerability, 030220 oncology & carcinogenesis, biology.protein, Antibody, Algorithms, Conjugate
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9Cathepsin B Is Dispensable for Cellular Processing of Cathepsin B-Cleavable Antibody–Drug Conjugates
المؤلفون: Tommy K. Cheung, Josefa Chuh, Katherine R. Kozak, Donglu Zhang, Yong Ma, Jack Sadowsky, Qui Phung, Robert W. Akita, Niña G. Caculitan, Byoung Chul Lee, Benjamin Haley, Yichin Liu, Andrew Polson, Mark X. Sliwkowski, Thomas H. Pillow
المصدر: Cancer Research. 77:7027-7037
مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Immunoconjugates, Antineoplastic Agents, Cathepsin B, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Humans, Prodrugs, Cells, Cultured, Cathepsin, Oligopeptide, Chemistry, Antibodies, Monoclonal, Valine, Cysteine protease, body regions, HEK293 Cells, 030104 developmental biology, Cell killing, Oncology, Monomethyl auristatin E, Biochemistry, 030220 oncology & carcinogenesis, Proteolysis, Citrulline, Drug Screening Assays, Antitumor, Oligopeptides, Linker, Cysteine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97963072f0241a139d445ff8921bb822
https://doi.org/10.1158/0008-5472.can-17-2391 -
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المؤلفون: Binqing Wei, Janet Gunzner-Toste, Guangmin Li, Helga Raab, Susan D. Spencer, Gail Lewis Phillips, Shang-Fan Yu, Katherine R. Kozak, Rachana Ohri, Jeffrey Lau, Philip Howard, Andrew Polson, Brian Safina, Luke Masterson, John A. Flygare, Thomas H. Pillow, Martine Darwish, Stephen J. Gregson, Gyoung-Dong Kang, Josefa dela Cruz-Chuh
المصدر: Journal of Medicinal Chemistry. 60:9490-9507
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Immunoconjugates, Cell Survival, Receptor, ErbB-2, Stereochemistry, Sialic Acid Binding Ig-like Lectin 2, Triazole, Pyrrolobenzodiazepine, Antineoplastic Agents, Breast Neoplasms, Benzodiazepines, Mice, 03 medical and health sciences, chemistry.chemical_compound, In vivo, Cell Line, Tumor, Neoplasms, Drug Discovery, Animals, Humans, Pyrroles, Maleimide, Piperazine, 030104 developmental biology, chemistry, Molecular Medicine, Female, Dimerization, Linker, Conjugate, Cysteine