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المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Butler SC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cui J; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cardello C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Liu C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Brunazzi EA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Baessler A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Xie B; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Kunning SR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Ngiow SF; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Huang YJ; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Manne S; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA, USA., Delgoffe GM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Wherry EJ; Institute for Immunology and Immune Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Kirkwood JM; Department of Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. Electronic address: dvignali@pitt.edu.

المصدر: Cell [Cell] 2024 Aug 08; Vol. 187 (16), pp. 4355-4372.e22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Lymphocyte Activation Gene 3 Protein* , Programmed Cell Death 1 Receptor*/metabolism , CD8-Positive T-Lymphocytes*/immunology , CD8-Positive T-Lymphocytes*/metabolism , Interferon-gamma*/metabolism , Mice, Inbred C57BL* , Antigens, CD*/metabolism, Animals ; Mice ; Autocrine Communication ; Humans ; Melanoma/immunology ; Melanoma/drug therapy ; Female ; Cell Line, Tumor ; Melanoma, Experimental/immunology ; T-Cell Exhaustion

المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Karapetyan L; Division of Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania., Kirkwood JM; Division of Hematology and Oncology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2022 Dec 01; Vol. 28 (23), pp. 5030-5039.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/drug therapy , Melanoma*/genetics , Programmed Cell Death 1 Receptor*, Humans ; Antigens, CD/metabolism ; CD8-Positive T-Lymphocytes ; Immunotherapy/methods ; Clinical Trials, Phase III as Topic

المؤلفون: Cillo AR; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Somasundaram A; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Shan F; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Integrative Systems Biology (ISB) Graduate Program, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Cardello C; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Workman CJ; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Kitsios GD; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Ruffin AT; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Graduate Program of Microbiology and Immunology (PMI), University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Kunning S; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Lampenfeld C; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Onkar S; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Graduate Program of Microbiology and Immunology (PMI), University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Grebinoski S; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Graduate Program of Microbiology and Immunology (PMI), University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA., Deshmukh G; Meso Scale Discovery, A division of Meso Scale Diagnostics, LLC, 1601 Research Boulevard, Rockville, MD 20850-3173, USA., Methe B; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Liu C; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Nambulli S; Center for Vaccine Research, University of Pittsburgh, 3501 Fifth Avenue, Pittsburgh, PA 15261, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Andrews LP; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Duprex WP; Center for Vaccine Research, University of Pittsburgh, 3501 Fifth Avenue, Pittsburgh, PA 15261, USA.; Department of Microbiology and Molecular Genetics, University of Pittsburgh, Pittsburgh, PA, USA., Joglekar AV; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Center for Systems Immunology, Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Benos PV; Department of Computer Science, University of Pittsburgh, 4200 Fifth Avenue, Pittsburgh, PA 15260, USA.; Department of Computational and Systems Biology, University of Pittsburgh, 3420 Forbes Avenue, Pittsburgh, PA 15213, USA., Ray P; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; University of Pittsburgh Asthma Institute at the University of Pittsburgh Medical Center, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA., Ray A; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; University of Pittsburgh Asthma Institute at the University of Pittsburgh Medical Center, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA., McVerry BJ; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Zhang Y; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Lee JS; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA.; Acute Lung Injury Center of Excellence, Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA., Das J; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Center for Systems Immunology, Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Singh H; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Center for Systems Immunology, Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Morris A; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Division of Pulmonary, Allergy and Critical Care Medicine, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15213, USA., Bruno TC; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Vignali DAA; Department of Immunology, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15260, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA.

المصدر: Cell reports. Medicine [Cell Rep Med] 2021 Dec 21; Vol. 2 (12), pp. 100476. Date of Electronic Publication: 2021 Dec 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101766894 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-3791 (Electronic) Linking ISSN: 26663791 NLM ISO Abbreviation: Cell Rep Med Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19/*immunology , COVID-19/*mortality , Lung/*immunology , SARS-CoV-2/*pathogenicity, Aged ; COVID-19/blood ; COVID-19/virology ; Critical Illness ; Cytokines/blood ; Gene Regulatory Networks ; Humans ; Inflammation ; Lung/virology ; Models, Theoretical ; Monocytes/immunology ; Myeloid Cells/immunology ; Reproducibility of Results ; Viral Load

المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Vignali KM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Szymczak-Workman AL; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA., Burton AR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA., Brunazzi EA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Ngiow SF; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Harusato A; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Sharpe AH; Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA., Wherry EJ; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Taniuchi I; RIKEN Center for Integrative Medical Sciences, Yokohama, Kanagawa, Japan., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA 15232, USA. Electronic address: dvignali@pitt.edu.

المصدر: Immunity [Immunity] 2021 Oct 12; Vol. 54 (10), pp. 2209-2217.e6. Date of Electronic Publication: 2021 Sep 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: CD4-Positive T-Lymphocytes/*cytology , Cell Differentiation/*immunology , Cell Lineage/*immunology , Gene Editing/*methods , Integrases/*genetics, Alleles ; Animals ; CD8-Positive T-Lymphocytes/cytology ; Cell Line ; Mice

المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Somasundaram A; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Moskovitz JM; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Szymczak-Workman AL; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Liu C; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Cillo AR; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Lin H; Department of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA., Normolle DP; Department of Biostatistics, University of Pittsburgh School of Public Health, Pittsburgh, PA, USA., Moynihan KD; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA., Taniuchi I; RIKEN Center for Integrative Medical Sciences, Yokohama City, Kanagawa, Japan., Irvine DJ; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Kirkwood JM; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Medicine, Division of Hematology/Oncology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Lipson EJ; Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, and Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ferris RL; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Department of Otolaryngology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Bruno TC; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dvignali@pitt.edu.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.

المصدر: Science immunology [Sci Immunol] 2020 Jul 17; Vol. 5 (49).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101688624 Publication Model: Print Cited Medium: Internet ISSN: 2470-9468 (Electronic) Linking ISSN: 24709468 NLM ISO Abbreviation: Sci Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, CD/*immunology , Drug Resistance, Neoplasm/*immunology , Immune Checkpoint Inhibitors/*therapeutic use , Programmed Cell Death 1 Receptor/*antagonists & inhibitors , T-Lymphocytes/*immunology, ADAM10 Protein/antagonists & inhibitors ; ADAM10 Protein/immunology ; Adenocarcinoma/drug therapy ; Adenocarcinoma/genetics ; Adenocarcinoma/immunology ; Adenocarcinoma/pathology ; Animals ; Antigens, CD/blood ; Antigens, CD/genetics ; Cell Line, Tumor ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/immunology ; Colonic Neoplasms/pathology ; Encephalomyelitis, Autoimmune, Experimental/immunology ; Female ; Head and Neck Neoplasms/drug therapy ; Head and Neck Neoplasms/immunology ; Head and Neck Neoplasms/pathology ; Humans ; Immunotherapy ; Male ; Melanoma, Experimental/drug therapy ; Melanoma, Experimental/immunology ; Melanoma, Experimental/pathology ; Mice, Transgenic ; Programmed Cell Death 1 Receptor/immunology ; Skin Neoplasms/drug therapy ; Skin Neoplasms/immunology ; Skin Neoplasms/pathology ; Squamous Cell Carcinoma of Head and Neck/drug therapy ; Squamous Cell Carcinoma of Head and Neck/immunology ; Squamous Cell Carcinoma of Head and Neck/pathology ; Transcriptome ; Lymphocyte Activation Gene 3 Protein

المؤلفون: Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Yano H; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Graduate Program of Microbiology and Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. dvignali@pitt.edu.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA. dvignali@pitt.edu.

المصدر: Nature immunology [Nat Immunol] 2019 Nov; Vol. 20 (11), pp. 1425-1434. Date of Electronic Publication: 2019 Oct 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Autoimmune Diseases/*drug therapy , B7 Antigens/*antagonists & inhibitors , Costimulatory and Inhibitory T-Cell Receptors/*antagonists & inhibitors , Immunotherapy/*methods , Neoplasms/*drug therapy, Antigens, CD/immunology ; Autoimmune Diseases/immunology ; B7 Antigens/immunology ; Costimulatory and Inhibitory T-Cell Receptors/immunology ; Drug Therapy, Combination/methods ; Hepatitis A Virus Cellular Receptor 2/antagonists & inhibitors ; Hepatitis A Virus Cellular Receptor 2/immunology ; Humans ; Ligands ; Molecular Targeted Therapy/methods ; Neoplasms/immunology ; Receptors, Immunologic/antagonists & inhibitors ; Receptors, Immunologic/immunology ; Signal Transduction/drug effects ; Signal Transduction/immunology ; Lymphocyte Activation Gene 3 Protein

المؤلفون: Yano H; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Graduate Program in Microbiology and Immunology (PMI), University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Workman CJ; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.; Tumor Microenvironment Center, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.; Cancer Immunology and Immunotherapy Program, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.

المصدر: Immunology [Immunology] 2019 Jul; Vol. 157 (3), pp. 232-247. Date of Electronic Publication: 2019 Jun 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Review

بيانات الدورية: Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0374672 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2567 (Electronic) Linking ISSN: 00192805 NLM ISO Abbreviation: Immunology Subsets: MEDLINE

مواضيع طبية MeSH: Tumor Escape*, Lymphocytes, Tumor-Infiltrating/*immunology , Neoplasms/*immunology , T-Lymphocytes, Regulatory/*immunology, Animals ; Chemokines/immunology ; Chemokines/metabolism ; Humans ; Inflammation Mediators/metabolism ; Lymphocytes, Tumor-Infiltrating/metabolism ; Lymphocytes, Tumor-Infiltrating/pathology ; Neoplasms/metabolism ; Neoplasms/pathology ; Phenotype ; Receptors, Chemokine/immunology ; Receptors, Chemokine/metabolism ; Signal Transduction ; T-Lymphocytes, Regulatory/metabolism ; T-Lymphocytes, Regulatory/pathology ; Tumor Microenvironment

المؤلفون: Ratay ML; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States., Glowacki AJ; Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States., Balmert SC; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States., Acharya AP; Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States., Polat J; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States., Andrews LP; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States., Fedorchak MV; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States., Schuman JS; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Fox Center for Vision Restoration, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States., Vignali DAA; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States; Department of Tumor Microenvironment Center, University of Pittsburgh Cancer Institute, Pittsburgh, PA 15232, United States., Little SR; Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA 15216, United States; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, United States; Department of Immunology, University of Pittsburgh School of Medicine, Pittsburgh, PA 15260, United States. Electronic address: srlittle@pitt.edu.

المصدر: Journal of controlled release : official journal of the Controlled Release Society [J Control Release] 2017 Jul 28; Vol. 258, pp. 208-217. Date of Electronic Publication: 2017 May 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: Netherlands NLM ID: 8607908 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4995 (Electronic) Linking ISSN: 01683659 NLM ISO Abbreviation: J Control Release Subsets: MEDLINE

مواضيع طبية MeSH: Anti-Inflammatory Agents/*administration & dosage , Chemokine CCL22/*administration & dosage , Delayed-Action Preparations/*chemistry , Dry Eye Syndromes/*complications , Inflammation/*prevention & control , T-Lymphocytes, Regulatory/*drug effects, Animals ; Anti-Inflammatory Agents/therapeutic use ; Chemokine CCL22/therapeutic use ; Disease Models, Animal ; Drug Delivery Systems ; Dry Eye Syndromes/immunology ; Female ; Inflammation/immunology ; Mice, Inbred BALB C ; T-Lymphocytes, Regulatory/immunology