المؤلفون: Sarah Dugdale, Ian Yule, Anthony R Knight, Chen I-Jen, Tim Haymes, Sean Lightowler, Heather Simmonite, Mike Comer, Anthony Padfield, Teresa Brooks, Allan M. Jordan, A Misra, Guy A. Kennett, Angela Merrett, Simon Bedford, K Benwell, Melanie Wong, Karine G. Poullennec, Loic LeStrat, Mark Reece, Burkhard Klenke

المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5945-5949

مصطلحات موضوعية: Receptor, Adenosine A2A, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Receptor, Adenosine A2B, Biochemistry, Receptor subtype, Pulmonary Disease, Chronic Obstructive, Administration, Inhalation, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Antagonist, Adenosine receptor, Asthma, In vitro, Adenosine A2 Receptor Antagonists, Rats, Pharmacokinetic analysis, Pyrimidines, Nociception, Drug Design, Molecular Medicine, Adenosine A2B receptor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cca22fbb50c8948de07dce59be48f66
https://doi.org/10.1016/j.bmcl.2009.08.040

المؤلفون: Ruth Botting, Dominic Surry, Stefania Leonardi, Xin Tong, Steven Michael Mcateer, Roger John Gillespie, Scott Murray Weiss, Gemma Caroline Stratton, Allan M. Jordan, Michael Griffin, Mike Comer, A Misra, Vicki Ruston, Daniel L Selwood, Angela Merrett, Anthony R Knight, Mark Reece, Suneel Gaur, Samantha J Bamford, Richard I. Todd, Joanne Lerpiniere, Rebecca Upton, Mona Saadi, Antony Padfield, Sean Lightowler, Sarah Denny

المصدر: Journal of Medicinal Chemistry. 52:33-47

مصطلحات موضوعية: Azoles, Receptor, Adenosine A2A, Drug Evaluation, Preclinical, Pharmacology, Mice, Structure-Activity Relationship, Pharmacokinetics, Drug Discovery, Haloperidol, medicine, Animals, Humans, Structure–activity relationship, Potency, Amines, Receptor, Gait Disorders, Neurologic, Molecular Structure, Chemistry, Dopaminergic, Adenosine receptor, Adenosine A2 Receptor Antagonists, Rats, Pyrimidines, Drug Design, Molecular Medicine, Antagonism, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93e49abb4598c637eefa7bed58fa2258
https://doi.org/10.1021/jm800961g

المؤلفون: Angela, Merrett, Patricia, Thomas, Anne, Stephens, Rola, Moghabghab, Marilyn, Gruneir

المصدر: The Canadian nurse. 107(8)

مصطلحات موضوعية: Geriatric Nursing, Interprofessional Relations, Humans, Accidental Falls, Cooperative Behavior, Nursing Staff, Hospital, Aged

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::9c80af7c10af83ac822554588c5df31a
https://pubmed.ncbi.nlm.nih.gov/22128708

المؤلفون: Hart Terance William, Rachel Parsons, Ben Gibbons, Helen Browne, Macias Alba, Heather Simmonite, Sarah Dugdale, Sean Lightowler, Howard Langh Am Mansell, Guy A. Kennett, Anthony Padfield, Geraint L. Francis, Robert M. Pratt, Teresa Brooks, Timothy Haymes, Jalanie D’Alessandro, Natalia Matassova, K Benwell, Melanie Wong, Steven B. Walls, Stephen D. Roughley, A Misra, Zoe Daniels, Angela Merrett, Alan D. Robertson, Kiri Tan

المصدر: Bioorganicmedicinal chemistry letters. 22(2)

مصطلحات موضوعية: Models, Molecular, ERG1 Potassium Channel, Stereochemistry, Clinical Biochemistry, Azetidine, Pharmaceutical Science, Stereoisomerism, Biochemistry, Amidohydrolases, chemistry.chemical_compound, Structure-Activity Relationship, Cytochrome P-450 Enzyme System, Fatty acid amide hydrolase, In vivo, Drug Discovery, Structure–activity relationship, Animals, Cytochrome P-450 Enzyme Inhibitors, Humans, Urea, Enzyme Inhibitors, Molecular Biology, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Anandamide, Ether-A-Go-Go Potassium Channels, Rats, nervous system, chemistry, Molecular Medicine, Azetidines, lipids (amino acids, peptides, and proteins), psychological phenomena and processes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1ef0471571a1b51d463d6743f77c74
https://pubmed.ncbi.nlm.nih.gov/22209458

المؤلفون: Brian Dymock, Allan E. Surgenor, Joseph Schoepfer, Christophe Fromont, Carlos Garcia-Echeverria, Suzanne A. Eccles, Angela Hayes, Melanie Valenti, Paul Brough, Angela Merrett, Roderick E. Hubbard, Nicholas G. M. Davies, Martin J. Drysdale, Michael Rugaard Jensen, Heather Simmonite, Thomas Radimerski, Andrew Massey, Allan M. Jordan, Alan D. Robertson, Michael Wood, Lisa Wright, Patrick Chène, Florence I. Raynaud, Paul Webb, Steven B. Walls, Swee Y. Sharp, Paul Workman, Ben Davis, Xavier Barril, Antony Padfield, Stephen D. Roughley, Rachel Parsons, Jenifer Borgognoni

المصدر: Journal of medicinal chemistry. 52(15)

مصطلحات موضوعية: Male, Molecular model, In silico, Administration, Oral, Antineoplastic Agents, Fluorescence Polarization, Crystallography, X-Ray, Binding, Competitive, Mice, Drug Discovery, Animals, Humans, HSP90 Heat-Shock Proteins, IC50, chemistry.chemical_classification, Mice, Inbred BALB C, biology, Chemistry, Cell growth, Hsp90, Xenograft Model Antitumor Assays, Enzyme, Pyrimidines, Biochemistry, Enzyme inhibitor, Chaperone (protein), biology.protein, Molecular Medicine, Female

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6259b30e505d42781708a3bb781d7d0
https://pubmed.ncbi.nlm.nih.gov/19610616

المؤلفون: Paul A. Brough, Xavier Barril, Jenifer Borgognoni, Patrick Chene, Nicholas G. M. Davies, Ben Davis, Martin J. Drysdale, Brian Dymock, Suzanne A. Eccles, Carlos Garcia-Echeverria, Christophe Fromont, Angela Hayes, Roderick E. Hubbard, Allan M. Jordan, Michael Rugaard Jensen, Andrew Massey, Angela Merrett, Antony Padfield, Rachel Parsons, Thomas Radimerski

المصدر: Journal of Medicinal Chemistry; Aug2009, Vol. 52 Issue 15, p4794-4809, 16p

المؤلفون: Roger J. Gillespie, Samantha J. Bamford, Ruth Botting, Mike Comer, Sarah Denny, Suneel Gaur, Michael Griffin, Allan M. Jordan, Anthony R. Knight, Joanne Lerpiniere, Stefania Leonardi, Sean Lightowler, Steven McAteer, Angela Merrett, Anil Misra, Antony Padfield, Mark Reece, Mona Saadi, Daniel L. Selwood, Gemma C. Stratton

المصدر: Journal of Medicinal Chemistry; Jan2009, Vol. 52 Issue 1, p33-47, 15p