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1دورية أكاديمية
المؤلفون: Kent Miner, Katja Labitzke, Benxian Liu, Paul Wang, Kathryn Henckels, Kevin Gaida, Robin Elliott, Jian Jeffrey Chen, Longbin Liu, Anh Leith, Esther Trueblood, Kelly Hensley, Xing-Zhong Xia, Oliver Homann, Brian Bennett, Mike Fiorino, John Whoriskey, Gang Yu, Sabine Escobar, Min Wong, Teresa L. Born, Alison Budelsky, Mike Comeau, Dirk Smith, Jonathan Phillips, James A. Johnston, Joseph G. McGivern, Kerstin Weikl, David Powers, Karl Kunzelmann, Deanna Mohn, Andreas Hochheimer, John K. Sullivan
المصدر: Frontiers in Pharmacology, Vol 10 (2019)
مصطلحات موضوعية: TMEM16A antagonist, niclosamide, nitazoxanide, bronchodilator, desensitization, airway smooth muscle (ASM), Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Jay Shendure, Choli Lee, Wei Yang, Beth Martin, Florence M. Chardon, Anh Leith, Wei Chen, Riza M. Daza, Junhong Choi, Chase C. Suiter
المصدر: Nat Biotechnol
مصطلحات موضوعية: Computer science, DNA repair, Biomedical Engineering, Bioengineering, Genomics, Computational biology, Applied Microbiology and Biotechnology, Prime (order theory), Article, chemistry.chemical_compound, CRISPR, Guide RNA, Indel, Subgenomic mRNA, Gene Editing, Genome, Cas9, Targeted Gene Repair, Palindrome, DNA, Expression (computer science), chemistry, Molecular Medicine, CRISPR-Cas Systems, Biotechnology, RNA, Guide, Kinetoplastida
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfacef00e68b01fb4a180411bcdc54b9
https://europepmc.org/articles/PMC8847327/ -
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المؤلفون: Diego Calderon, Anh Leith, Beth Martin, Andria Ellis, Riza M. Daza, Florence M. Chardon, Jacob M. Tome, Cole Trapnell, Wei Chen, Choli Lee, Jay Shendure
مصطلحات موضوعية: Regulation of gene expression, Reporter gene, Chemistry, Multiplex, Computational biology, Trans-acting, Enhancer, Transcription factor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::80793b6178dd9940fb3e4654b02fa538
https://doi.org/10.1101/2020.09.30.321323 -
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المؤلفون: Sharon Wannberg, James B. Rottman, Sabine S. Escobar, Joel Tocker, Daniela Metz, Michael R. Comeau, Deanna Mohn, Kira Misura, Alison L. Budelsky, Anh Leith, Erika Rickel, Lori Siegel, John K. Sullivan, Cynthia R. Willis
المصدر: American Journal of Respiratory Cell and Molecular Biology. 53:810-821
مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Carbachol, Myocytes, Smooth Muscle, Clinical Biochemistry, Gene Expression, Bronchi, Proinflammatory cytokine, Contractility, medicine, Animals, Humans, Receptor, Molecular Biology, Cells, Cultured, Asthma, Mice, Knockout, Mice, Inbred BALB C, Receptors, Interleukin-17, business.industry, Interleukins, Interleukin-17, Interleukin, Cell Biology, respiratory system, medicine.disease, respiratory tract diseases, Mice, Inbred C57BL, Immunology, Methacholine, Interleukin 17, business, Muscle Contraction, Signal Transduction, medicine.drug
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المؤلفون: Riza M. Daza, Molly Gasperini, Jay Shendure, Anh Leith, Xingfan Huang, Joseph D. Janizek, Lea M. Starita, Zhang, Beth Martin, Gregory M. Findlay
مصطلحات موضوعية: 0303 health sciences, 030305 genetics & heredity, Genomics, Computational biology, Biology, ENCODE, Germline, 3. Good health, 03 medical and health sciences, Exon, Genome editing, 13. Climate action, Genetic variation, RNA splicing, Gene, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f964e7f1c9815ec367e262f7fb6a504d
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المؤلفون: Joseph D. Janizek, Lea M. Starita, Beth Martin, Gregory M. Findlay, Jay Shendure, Xingfan Huang, Riza M. Daza, Melissa D. Zhang, Anh Leith, Molly Gasperini
المصدر: Nature
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Genomics, Computational biology, Biology, ENCODE, Genome, Article, Germline, Cell Line, 03 medical and health sciences, Genome editing, Loss of Function Mutation, genome editing, Humans, Genetic Predisposition to Disease, RNA, Messenger, Gene, Gene Editing, Multidisciplinary, Genes, Essential, BRCA1 Protein, Genome, Human, Genetic Variation, Recombinational DNA Repair, Exons, BRCA1, Prognosis, Human genetics, VUS, 3. Good health, 030104 developmental biology, Hereditary Breast and Ovarian Cancer Syndrome, Female, Functional genomics, functional assay
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المؤلفون: Cole Trapnell, Jacob Schreiber, Dana Jackson, Nadav Ahituv, José L. McFaline-Figueroa, Seungsoo Kim, William Stafford Noble, Jay Shendure, Molly Gasperini, Melissa D. Zhang, Andrew J. Hill, Anh Leith, Beth Martin
المصدر: Cell, vol 176, iss 1-2
مصطلحات موضوعية: Medical and Health Sciences, Genome, 0302 clinical medicine, 2.1 Biological and endogenous factors, CRISPR, Clustered Regularly Interspaced Short Palindromic Repeats, Gene Regulatory Networks, Aetiology, 0303 health sciences, Chromosome Mapping, Genomics, Biological Sciences, single cell, Enhancer Elements, Genetic, genetic screen, Human, Biotechnology, Enhancer Elements, 1.1 Normal biological development and functioning, Quantitative Trait Loci, human genetics, Computational biology, Biology, eQTL, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Genetic, Underpinning research, Genetics, Humans, Enhancer, Gene, crisprQTL, 030304 developmental biology, Genome, Human, Gene Expression Profiling, Human Genome, CRISPRi, Stem Cell Research, Human genetics, Gene Expression Regulation, Expression quantitative trait loci, Human genome, enhancer, Generic health relevance, RNA-seq, CRISPR-Cas Systems, gene regulation, 030217 neurology & neurosurgery, Developmental Biology, Genetic screen, Genome-Wide Association Study, Transcription Factors
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871cd95dc7be24ccc23e7f8852be0e16
https://doi.org/10.1016/j.cell.2019.02.027 -
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المؤلفون: Cynthia R Willis, Yi-Ling Hu, Anh Leith, James B Rottman
المصدر: The Journal of Immunology. 182:34.3-34.3
مصطلحات موضوعية: Immunology, Immunology and Allergy
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3677d6dd2025e4a2737e999cb1a08a73
https://doi.org/10.4049/jimmunol.182.supp.34.3 -
10دورية أكاديمية
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