يعرض 1 - 10 نتائج من 31 نتيجة بحث عن '"Anirudh Prahallad"', وقت الاستعلام: 0.83s تنقيح النتائج
  1. 1
    دورية أكاديمية
    Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models

    المؤلفون: Kathleen Sprouffske, Grainne Kerr, Cheng Li, Anirudh Prahallad, Ramona Rebmann, Verena Waehle, Ulrike Naumann, Hans Bitter, Michael R Jensen, Francesco Hofmann, Saskia M Brachmann, Stéphane Ferretti, Audrey Kauffmann

    المصدر: Computational and Structural Biotechnology Journal, Vol 18, Iss , Pp 323-331 (2020)

    مصطلحات موضوعية: Heterogeneity, Clonal evolution, Breast cancer, Metastasis, Patient derived xenograft models, Biotechnology, TP248.13-248.65

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2001037019302879; https://doaj.org/toc/2001-0370

    URL الوصول: https://doaj.org/article/f59eeb0474a14975baefb2770967be51

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  2. 2
    دورية أكاديمية
    PTPN11 Is a Central Node in Intrinsic and Acquired Resistance to Targeted Cancer Drugs

    المؤلفون: Anirudh Prahallad, Guus J.J.E. Heynen, Giovanni Germano, Stefan M. Willems, Bastiaan Evers, Loredana Vecchione, Valentina Gambino, Cor Lieftink, Roderick L. Beijersbergen, Federica Di Nicolantonio, Alberto Bardelli, Rene Bernards

    المصدر: Cell Reports, Vol 12, Iss 12, Pp 1978-1985 (2015)

    مصطلحات موضوعية: Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211124715009225; https://doaj.org/toc/2211-1247

    URL الوصول: https://doaj.org/article/ecb00508ecca451a9aef4546ea85d00b

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  3. 3
    دورية أكاديمية
    Intrinsic Resistance to MEK Inhibition in KRAS Mutant Lung and Colon Cancer through Transcriptional Induction of ERBB3

    المؤلفون: Chong Sun, Sebastijan Hobor, Andrea Bertotti, Davide Zecchin, Sidong Huang, Francesco Galimi, Francesca Cottino, Anirudh Prahallad, Wipawadee Grernrum, Anna Tzani, Andreas Schlicker, Lodewyk F.A. Wessels, Egbert F. Smit, Erik Thunnissen, Pasi Halonen, Cor Lieftink, Roderick L. Beijersbergen, Federica Di Nicolantonio, Alberto Bardelli, Livio Trusolino, Rene Bernards

    المصدر: Cell Reports, Vol 7, Iss 1, Pp 86-93 (2014)

    مصطلحات موضوعية: Biology (General), QH301-705.5

    وصف الملف: electronic resource

    Relation: http://www.sciencedirect.com/science/article/pii/S2211124714001612; https://doaj.org/toc/2211-1247

    URL الوصول: https://doaj.org/article/a91292cb8a2f4412b3021bca6241b5b1

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  4. 4
    A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors

    المؤلفون: Ana Ruiz-Saenz, Chloe E. Atreya, Changjun Wang, Bo Pan, Courtney A. Dreyer, Diede Brunen, Anirudh Prahallad, Denise P. Muñoz, Dana J. Ramms, Valeria Burghi, Danislav S. Spassov, Eleanor Fewings, Yeonjoo C. Hwang, Cynthia Cowdrey, Christina Moelders, Cecilia Schwarzer, Denise M. Wolf, Byron Hann, Scott R. VandenBerg, Kevan Shokat, Mark M. Moasser, René Bernards, J. Silvio Gutkind, Laura J. van ‘t Veer, Jean-Philippe Coppé

    المساهمون: Medical Oncology

    المصدر: Nature cancer, vol 4, iss 2
    Nature Cancer, 4(2), 240-256. Nature Research

    مصطلحات موضوعية: Proto-Oncogene Proteins B-raf, Cancer Research, MAP Kinase Signaling System, Colo-Rectal Cancer, ErbB Receptors, src-Family Kinases, Oncology, SDG 3 - Good Health and Well-being, Cyclooxygenase 2, 5.1 Pharmaceuticals, Humans, Development of treatments and therapeutic interventions, Colorectal Neoplasms, Digestive Diseases, Cancer

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d9e001b5e77db572bc8303604ef49a
    https://doi.org/10.1038/s43018-022-00508-5

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  5. 5
    Preclinical studies on the use of a P-selectin-blocking monoclonal antibody to halt progression of myelofibrosis in the Gata1 mouse model

    المؤلفون: Paola Verachi, Francesca Gobbo, Fabrizio Martelli, Mario Falchi, Antonio di Virgilio, Giuseppe Sarli, Celine Wilke, Andreas Bruederle, Anirudh Prahallad, Francesca Arciprete, Maria Zingariello, Anna Rita Migliaccio

    المصدر: Experimental Hematology. 117:43-61

    مصطلحات موضوعية: Cancer Research, Genetics, Cell Biology, Hematology, Molecular Biology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4c9ad3fe22a5ed55e99a9de7fd9c85
    https://doi.org/10.1016/j.exphem.2022.09.004

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  6. 6
    Siremadlin, a Human Double Minute-2 (HDM2) Inhibitor, Added to Ruxolitinib after Suboptimal Response to Ruxolitinib Alone in Patients with Myelofibrosis: Results from Part 1 of the Phase 1/2 Adore Study

    المؤلفون: Florian H Heidel, Andrew Charles Perkins, Andreas Reiter, Carl C. Crodel, Caroline Hasselbalch Riley, María Teresa Gómez-Casares, Istvan Takacs, Heiko Becker, Thomas Lehmann, Olga Vinogradova, Kate Burbury, Alessandro M. Vannucchi, Vikas Gupta, Claire Harrison, Marielle Wondergem, Jean-Jacques Kiladjian, Grace Cleary, Angela Zhang, Bruyère Mahuzier, Jagannath Kota, Anirudh Prahallad, David M Ross

    المصدر: Blood. 140:590-593

    مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::95c80d3c2ee4b6813cdad730c8b755c9
    https://doi.org/10.1182/blood-2022-158501

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  7. 7
    Ruxolitinib in Pediatric Patients with Treatment-Naïve or Steroid-Refractory Acute Graft-Versus-Host Disease: Primary Findings from the Phase I/II REACH4 Study

    المؤلفون: Franco Locatelli, Hyoung Jin Kang, Bénédicte Bruno, Virginie Gandemer, Fanny Rialland, Maura Faraci, Yoshiyuki Takahashi, Katsuyoshi Koh, Henrique Bittencourt, Grace Cleary, Christine Rosko, Pantelia Roussou, Annie St. Pierre, Anirudh Prahallad, Cristina Díaz-de-Heredia

    المصدر: Blood. 140:1376-1378

    مصطلحات موضوعية: Immunology, Cell Biology, Hematology, Biochemistry

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::426ef55e774b0b2658ab8b3d6882ef80
    https://doi.org/10.1182/blood-2022-155708

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  8. 8
    Genetic heterogeneity and clonal evolution during metastasis in breast cancer patient-derived tumor xenograft models

    المؤلفون: Cheng Li, Francesco Hofmann, Kathleen Sprouffske, Ramona Rebmann, Verena Waehle, Saskia M. Brachmann, Michael Rugaard Jensen, Stephane Ferretti, Grainne Kerr, Anirudh Prahallad, Ulrike Naumann, Audrey Kauffmann, Hans Bitter

    المصدر: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 323-331 (2020)
    Computational and Structural Biotechnology Journal

    مصطلحات موضوعية: lcsh:Biotechnology, Biophysics, Genomics, Biology, Biochemistry, Somatic evolution in cancer, Metastasis, 03 medical and health sciences, Breast cancer, 0302 clinical medicine, Stroma, Structural Biology, lcsh:TP248.13-248.65, Genetics, medicine, Exome sequencing, ComputingMethodologies_COMPUTERGRAPHICS, 030304 developmental biology, 0303 health sciences, Clonal evolution, Genetic heterogeneity, medicine.disease, Primary tumor, Computer Science Applications, Patient derived xenograft models, 030220 oncology & carcinogenesis, Cancer research, Heterogeneity, Research Article, Biotechnology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19375bcf82f7cffe17ea28ced78c6478
    https://doi.org/10.1016/j.csbj.2020.01.008

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  9. 9
    Abstract P124: JDQ443, a covalent irreversible inhibitor of KRAS G12C, exhibits a novel binding mode and demonstrates potent anti-tumor activity and favorable pharmacokinetic properties in preclinical models

    المؤلفون: Saskia M. Brachmann, Andreas Weiss, Daniel A. Guthy, Kim Beyer, Johannes Voshol, Michel Maira, Anirudh Prahallad, Diana Graus Porta, Christian Schnell, Nils Ostermann, Andrea Vaupel, Marc Gerspacher, Catherine Leblanc, Dirk Erdmann, Dario Sterker, Grainne Kerr, Giovannoni Jerome, Victoria Head, Rowan Stringer, Ruben De Kanter, Kearns Jeff, Danielle Roman, Toni Widmer, Peter Wessels, Eloisa Jimenez Nunez, Richard Sedrani, Frederic Zecri, Francesco Hofmann, Jeff Engleman, Edwige Lorthiois, Simona Cotesta

    المصدر: Molecular Cancer Therapeutics. 20:P124-P124

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ad4b8e929a5d91731e7278c2de32193c
    https://doi.org/10.1158/1535-7163.targ-21-p124

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  10. 10
    Modelling signalling networks from perturbation data

    المؤلفون: Mathurin Dorel, Torsten Gross, Anja Sieber, Nils Blüthgen, Evert Bosdriesz, Lodewyk F. A. Wessels, Bertram Klinger, Anirudh Prahallad

    المساهمون: Bioinformatics

    المصدر: Bioinformatics, 34(23), 4079-4086. Oxford University Press
    Dorel, M, Klinger, B, Gross, T, Sieber, A, Prahallad, A, Bosdriesz, E, Wessels, L F A & Blüthgen, N 2018, ' Modelling signalling networks from perturbation data ', Bioinformatics, vol. 34, no. 23, pp. 4079-4086 . https://doi.org/10.1093/bioinformatics/bty473

    مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Computer science, medicine.medical_treatment, Protein Tyrosine Phosphatase, Non-Receptor Type 11, Computational biology, Biochemistry, Targeted therapy, Cell Line, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Cell Line, Tumor, medicine, Humans, Intracellular signalling, Protein kinase A, Molecular Biology, Network model, Protein Tyrosine Phosphatase, Non-Receptor Type 11/genetics, Tumor, Akt signalling, 030102 biochemistry & molecular biology, business.industry, MAPK signalling, Colon cancer cell line, A protein, Computational Biology, Modular design, Computer Science Applications, Non-Receptor Type 11/genetics, Computational Mathematics, 030104 developmental biology, Signalling, Computational Theory and Mathematics, Colonic Neoplasms, Protein Tyrosine Phosphatase, Signal transduction, business, Software, Signal Transduction

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f007d6cb6b68ab4c38d58ee80ea40492
    https://doi.org/10.1093/bioinformatics/bty473

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