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المؤلفون: Kirk W. Johnson, Baolin Li, Ann Marie L. Ogden, David Bleakman, Yuewei Qian, Elizabeth Rex, He Wang
المصدر: ASSAY and Drug Development Technologies. 14:131-143
مصطلحات موضوعية: 0301 basic medicine, Glutamic Acid, Heterologous, Kainate receptor, Biology, Receptors, N-Methyl-D-Aspartate, Structure-Activity Relationship, 03 medical and health sciences, 0302 clinical medicine, Receptors, Kainic Acid, Postsynaptic potential, Drug Discovery, Neuropilin, Humans, Receptor, Cells, Cultured, Dose-Response Relationship, Drug, HEK 293 cells, Intracellular Signaling Peptides and Proteins, Membrane Proteins, Molecular biology, High-Throughput Screening Assays, Cell biology, HEK293 Cells, 030104 developmental biology, Membrane protein, Molecular Medicine, Disks Large Homolog 4 Protein, Postsynaptic density, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc2dcd1cfbc045872ce44c19909351fd
https://doi.org/10.1089/adt.2015.689 -
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المؤلفون: Brian M. Arnold, Miriam del Prado, Smriti Iyengar, Edward L. Mattiuz, Zhipei Wu, Mark A. Winter, David Bleakman, Ken H. Ho, Ann Marie L. Ogden, Paul L. Ornstein, Carrie K. Jones, Sandra Ann Filla, Brian Michael Mathes, Michael Gregory Bell, Douglas Richard Stack, Ana Maria Escribano, Thomas J. Bleisch, Ana I. Mateo, Kevin John Hudziak, Andrew Alt, Rosa Maria A. Simmons, Harlan E. Shannon, Robert E. Stratford, Jose A. Martinez-Perez, Esteban Dominguez, Ana M. Castaño
المصدر: Bioorganic & Medicinal Chemistry Letters. 23:6459-6462
مصطلحات موضوعية: Molecular Sequence Data, Clinical Biochemistry, Administration, Oral, Pain, Pharmaceutical Science, Pharmacology, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Receptors, Kainic Acid, Oral administration, In vivo, Drug Discovery, Animals, Prodrugs, Amino Acid Sequence, Molecular Biology, Benzoic acid, chemistry.chemical_classification, Chemistry, Organic Chemistry, Haplorhini, Prodrug, Isoquinolines, Amino acid, Disease Models, Animal, Molecular Medicine
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المؤلفون: Gary Gilmour, Ann Marie L. Ogden, Sally Loomis, Anthony J. Baucum, Teri L. Belecky-Adams, Jonathan M. Wilson, Kalpana M. Merchant
المصدر: Neuropharmacology. 99
مصطلحات موضوعية: Agonist, Male, medicine.medical_specialty, PF-2545920, medicine.drug_class, Phosphodiesterase Inhibitors, Mice, Transgenic, Medium spiny neuron, c-Fos, Rats, Sprague-Dawley, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Random Allocation, Dopamine receptor D1, Dopamine receptor D2, Internal medicine, Basal ganglia, medicine, Haloperidol, Animals, Pharmacology, Neurons, biology, Dose-Response Relationship, Drug, Phosphoric Diester Hydrolases, Receptors, Dopamine D2, Receptors, Dopamine D1, Benzazepines, Mice, Inbred C57BL, Neostriatum, Dopamine D2 Receptor Antagonists, Endocrinology, nervous system, chemistry, Dopamine Agonists, biology.protein, Quinolines, Pyrazoles, Proto-Oncogene Proteins c-fos, medicine.drug
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المؤلفون: Edward L. Mattiuz, Ann Marie L. Ogden, Ana M. Castaño, Zhipei Wu, Robert E. Stratford, E. Dominguez, Thomas J. Bleisch, Brian Michael Mathes, Brian M. Arnold, David Bleakman, Smriti Iyengar, Rosa Maria A. Simmons, Harlan E. Shannon, Sandra Ann Filla, Jose A. Martinez-Perez, Douglas Richard Stack, Ana I. Mateo, Miriam del Prado, Kevin John Hudziak, Andrew Alt, Michael Gregory Bell, Carrie K. Jones, Paul L. Ornstein, Jennifer L. Buckmaster, Ana Maria Escribano, Mark A. Winter, Ken H. Ho
المصدر: Journal of Medicinal Chemistry. 48:4200-4203
مصطلحات موضوعية: Analgesic, Biological Availability, Pain, Kainate receptor, Pharmacology, Cell Line, Receptors, Kainic Acid, Drug Discovery, Animals, Humans, Receptors, AMPA, Amino Acids, Receptor, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, chemistry.chemical_classification, Analgesics, Chemistry, Glutamate receptor, Antagonist, Prodrug, Recombinant Proteins, Rats, Amino acid, Disease Models, Animal, Spinal Cord, Biochemistry, Hyperalgesia, Molecular Medicine, Licking
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المؤلفون: Mary Gates, Michael J. O'Neill, Katherine Whalley, David Bleakman, David M. Lodge, Jim Vandergriff, Dennis M. Zimmerman, Phil Skolnick, Mark A Ward, Tracey K. Murray, Eric S. Nisenbaum, Edward R. Siuda, Polly Baumbarger, Caroline A Hicks, Christine S. Robinson, Ann Marie L. Ogden
المصدر: Journal of Pharmacology and Experimental Therapeutics. 306:752-762
مصطلحات موضوعية: Male, Prefrontal Cortex, Substantia nigra, Dioxoles, AMPA receptor, Pharmacology, Biology, Hippocampus, Neuroprotection, Rats, Sprague-Dawley, GAP-43 Protein, Piperidines, Neurotrophic factors, Excitatory Amino Acid Agonists, medicine, Animals, Humans, Receptors, AMPA, Oxidopamine, Receptor, alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid, Cells, Cultured, Neurons, Biphenyl Compounds, Glutamate receptor, Neurotoxicity, Parkinson Disease, Potentiator, medicine.disease, Amides, Corpus Striatum, Rats, Substantia Nigra, Disease Models, Animal, Neuroprotective Agents, Receptors, Glutamate, nervous system, 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine, Molecular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c286526e10b9e75c20dc622a880e6947
https://doi.org/10.1124/jpet.103.049445 -
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المؤلفون: Ken H. Ho, Edward L. Mattiuz, Ann Marie L. Ogden, Brian Michael Mathes, Ana I. Mateo, David Bleakman, Kevin John Hudziak, Donna K. Dieckman, Sandra Ann Filla, Mark A. Winter, Thomas J. Bleisch, Ana Maria Escribano, Paul L. Ornstein, Kirk W. Johnson, Douglas Richard Stack, Amy Clemens-Smith, Miriam del Prado, Ana M. Castaño, Mary A. Katofiasc, Robert E. Stratford, E. Dominguez, Michael Gregory Bell, Lee A. Phebus, Jose A. Martinez-Perez
المصدر: Journal of Medicinal Chemistry. 45:4383-4386
مصطلحات موضوعية: Stereochemistry, Migraine Disorders, Carboxylic Acids, Administration, Oral, Biological Availability, Kainate receptor, Pharmacology, Cell Line, Radioligand Assay, Receptors, Kainic Acid, Drug Discovery, medicine, Animals, Humans, Prodrugs, Rats, Wistar, Receptor, Dose-Response Relationship, Drug, Chemistry, Antagonist, Glutamate receptor, Esters, Biological activity, Prodrug, Isoquinolines, Rats, Disease Models, Animal, Mechanism of action, Competitive antagonist, Acute Disease, Molecular Medicine, Calcium, medicine.symptom, Excitatory Amino Acid Antagonists
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المؤلفون: Miriam del Prado, Ken H. Ho, Brian Michael Mathes, Smriti Iyengar, Mark A. Winter, Harlan E. Shannon, Carrie K. Jones, David K. Clawson, Ana Maria Escribano, Douglas Richard Stack, Esteban Dominguez, Paul L. Ornstein, Ana I. Mateo, Jose A. Martinez-Perez, Kevin John Hudziak, Andrew Alt, Edward L. Mattiuz, Brian M. Arnold, Sandra Ann Filla, Thomas J. Bleisch, Ana M. Castaño, Michael Gregory Bell, Rosa Maria A. Simmons, Robert E. Stratford, Ann Marie L. Ogden, Zhipei Wu, David Bleakman
المصدر: Bioorganicmedicinal chemistry letters. 23(23)
مصطلحات موضوعية: Male, Stereochemistry, Clinical Biochemistry, Analgesic, Molecular Sequence Data, Pharmaceutical Science, Administration, Oral, Pain, Tetrazoles, Biochemistry, Rats, Sprague-Dawley, chemistry.chemical_compound, Structure-Activity Relationship, Receptors, Kainic Acid, In vivo, Drug Discovery, Animals, Tetrazole, Prodrugs, Amino Acid Sequence, Receptor, Molecular Biology, Organic Chemistry, Prodrug, Isoquinolines, In vitro, Rats, Disease Models, Animal, chemistry, Molecular Medicine, Selectivity, Linker
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المؤلفون: Norton P. Peet, Ann Marie L. Ogden, David A. Demeter, Herschel J. R. Weintraub, Elaine C. Meng, Mark W. Dudley, Nelsen L. Lentz, Philippe Bey
المصدر: ChemInform. 22
مصطلحات موضوعية: Stereochemistry, Chemistry, medicine, Purine derivative, General Medicine, Adenosine receptor, Adenosine, medicine.drug
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المؤلفون: M. A. Staeger, Yaw Senyah, Miller Francis P, Timothy C. McCloskey, Ann Marie L. Ogden, Herbert J. Ketteler, John M. Kane, John H. Kehne, Dalton Christopher R, P. A. Chmielewski, Mark W. Dudley, Jerry A. Miller
المصدر: ChemInform. 25
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Aryl, Triazole derivatives, General Medicine, Strychnine, Medicinal chemistry
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المصدر: Journal of Medicinal Chemistry. 35:3263-3269
مصطلحات موضوعية: Cerebral Cortex, Steric effects, Molecular Structure, Pyrimidine, Stereochemistry, Molecular Conformation, Receptors, Purinergic, Substituent, Stereoisomerism, Adenosine receptor, Adenosine, Rats, chemistry.chemical_compound, Adenosine A1 receptor, Pyrimidines, chemistry, Purines, Drug Discovery, medicine, Animals, Pyrazoles, Molecular Medicine, Enantiomer, Receptor, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c4bd8f579f3cc7af14990f3df5c55f
https://doi.org/10.1021/jm00095a024
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