المؤلفون: Marie Brännström, Pär Nordell, Britta Bonn, Andrew M. Davis, Anna-Pia Palmgren, Constanze Hilgendorf, Katarina Rubin, Ken Grime

المصدر: Pharmaceutics, Vol 7, Iss 4, Pp 554-564 (2015)

مصطلحات موضوعية: montelukast, OATP2B1, OATP1B1, hepatic uptake, transporters, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: http://www.mdpi.com/1999-4923/7/4/554; https://doaj.org/toc/1999-4923

URL الوصول: https://doaj.org/article/b7ecb137ad394c7fbfe6e98e03d50658

المؤلفون: Christian Tyrchan, Anna-Pia Palmgren, Hui-Fang Amy Chang, Yunhua Chen, Victoria Ullah, Karin Björhall, Annika Westin Eriksson, Rebecca Fransson, Mickael Mogemark, Tiiu Wennberg, Shuchun Zhao, Bold Peter, Linda Fredlund, Matthew Thomas, Eva Lamm Bergström, Nils Pemberton, Ulf Börjesson, Reed W. Smith, Mikael Brűlls, Johan Carlsson, Britt-Marie Fihn, Linda Öster, Mio Rodrigo Blomqvist, Hongbin Ge, Antonios Nikitidis, Wenzhen Yang, Anders Eriksson, Haijuan Huang, Sarah Lever, Perry Matthew, Kostas Karabelas, Helena Lindmark, Jens Petersen

المصدر: Journal of medicinal chemistry. 64(12)

مصطلحات موضوعية: Male, Class I Phosphatidylinositol 3-Kinases, Ovalbumin, High selectivity, Pharmacology, Crystallography, X-Ray, 01 natural sciences, 03 medical and health sciences, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, Rats, Inbred BN, Drug Discovery, medicine, Asthmatic patient, Potency, Structure–activity relationship, Animals, Class Ib Phosphatidylinositol 3-Kinase, Humans, Short duration, Protein Kinase Inhibitors, 030304 developmental biology, Asthma, 0303 health sciences, Sulfonamides, biology, Inhalation, Molecular Structure, Chemistry, medicine.disease, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Thiazoles, biology.protein, Leukocytes, Mononuclear, Molecular Medicine, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f1afe7cc480e1edf37ab207774eb9ff
https://pubmed.ncbi.nlm.nih.gov/34080862

المؤلفون: Britta Bonn, Andrew M. Davis, Ken Grime, Constanze Hilgendorf, Anna-Pia Palmgren, Katarina Rubin, Pär Nordell, Marie Brännström

المصدر: Pharmaceutics
Volume 7
Issue 4
Pages 554-564
Pharmaceutics, Vol 7, Iss 4, Pp 554-564 (2015)

مصطلحات موضوعية: chemistry.chemical_classification, business.industry, OATP2B1, Carboxylic acid, HEK 293 cells, Significant difference, OATP1B1, lcsh:RS1-441, Pharmaceutical Science, Transporter, Absorption (skin), Disposition, transporters, Pharmacology, Article, lcsh:Pharmacy and materia medica, hepatic uptake, chemistry, Cell culture, montelukast, medicine, business, Montelukast, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8be5d67ecd391cda2e8db017fd4d91db

المؤلفون: Britt-Marie Fihn, Anna-Pia Palmgren, Paul Courtney, Ken Grime, James Bird

المصدر: Xenobiotica; the fate of foreign compounds in biological systems. 43(6)

مصطلحات موضوعية: Cell Maintenance, Time Factors, Health, Toxicology and Mutagenesis, Cell, Organic Anion Transporters, Cell Separation, Matrix (biology), Pharmacology, Toxicology, Biochemistry, Substrate Specificity, Dogs, Cytochrome P-450 Enzyme System, Suspensions, medicine, Atorvastatin, Animals, Humans, Pyrroles, Primary cell, Glucuronosyltransferase, chemistry.chemical_classification, Cryopreservation, biology, Biological Transport, General Medicine, Enzyme assay, Rats, medicine.anatomical_structure, Enzyme, chemistry, Pharmaceutical Preparations, Heptanoic Acids, Hepatocyte, biology.protein, Hepatocytes, Drug metabolism

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc114ca20fb56602d50719e6dc3dd16
https://pubmed.ncbi.nlm.nih.gov/23137276