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1
المؤلفون: Oscar Della Pasqua, Meindert Danhof, Huixin Yu, Ramona Graf, Vincent F.S. Dubois, Giovanni Smania, Anne S. Y. Chain
المصدر: British Journal of Clinical Pharmacology. 83:349-362
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Proarrhythmia, business.industry, Prolongation, Sotalol, medicine.disease, 030226 pharmacology & pharmacy, QT interval, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Cisapride, Moxifloxacin, Anesthesia, Linear regression, Medicine, Pharmacology (medical), business, Screening procedures, medicine.drug
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2
المؤلفون: Sebastian Polak, Blanca Rodriguez, Elisa Passini, Patrick Fanelli, Jin Zhai, Kevin Fitzgerald, Jeffrey Travis, Pierre Morissette, Anne S. Y. Chain, Frederick Sannajust, Christopher P. Regan
المصدر: Journal of Pharmacological and Toxicological Methods. 105:106804
مصطلحات موضوعية: Pharmacology, Guinea pig, medicine.medical_specialty, Arrhythmic risk, business.industry, Internal medicine, In silico, Qtc interval prolongation, Cardiology, Medicine, Toxicology, business
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3Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions
المؤلفون: Albert Hofman, Meindert Danhof, Oscar Della Pasqua, Charlotte van Noord, Jeanne P. Dieleman, Bruno H. Stricker, Anne S. Y. Chain, Miriam C. J. M. Sturkenboom
المصدر: British Journal of Clinical Pharmacology. 76:964-972
مصطلحات موضوعية: Pharmacology, education.field_of_study, medicine.medical_specialty, business.industry, Population, Sotalol, QT interval, Confidence interval, Rotterdam Study, Relative risk, Internal medicine, Anesthesia, Cohort, Cardiology, Medicine, Pharmacology (medical), education, business, Cohort study, medicine.drug
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4
المؤلفون: Meindert Danhof, Miriam C. J. M. Sturkenboom, Vincent F.S. Dubois, Anne S. Y. Chain, Oscar Della Pasqua
المصدر: British Journal of Clinical Pharmacology. 76:708-724
مصطلحات موضوعية: Pharmacology, business.industry, Long QT syndrome, Sotalol, Prolongation, medicine.disease, QT interval, Crossover study, Cisapride, Moxifloxacin, Pharmacodynamics, medicine, Pharmacology (medical), business, medicine.drug
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5
المساهمون: Medical Informatics
المصدر: Drug Discovery Today, 10(3), e373-e383. Elsevier Ltd.
مصطلحات موضوعية: Cardiovascular safety, business.industry, Drug Evaluation, Preclinical, Clinical settings, Drugs, Investigational, Pharmacology, Cardiovascular System, Translational Research, Biomedical, Drug development, New chemical entity, Pharmacology, Clinical, Drug Discovery, Animals, Humans, Molecular Medicine, Medicine, business
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6
المؤلفون: Pamela Gerenser, Christopher P. Regan, Spencer J. Dech, Anne S. Y. Chain, Pierre Morissette, Patrick Fanelli, Jeffrey Travis, Frederick Sannajust
المصدر: Journal of Pharmacological and Toxicological Methods. 88:208
مصطلحات موضوعية: Pharmacology, Drug development, Arrhythmic risk, business.industry, In silico, Medicine, Toxicology, Bioinformatics, business, Comparative evaluation
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7
المؤلفون: Meindert Danhof, Anne S. Y. Chain, David J. Spalding, O Della Pasqua, Dymphy R.H. Huntjens, Scott G. Summerfield, A Metcalf, A Strougo
المصدر: British Journal of Pharmacology. 153:1072-1084
مصطلحات موضوعية: Pharmacology, education.field_of_study, Chemistry, Population, Flurbiprofen, Intestinal absorption, NONMEM, Diclofenac, Pharmacokinetics, Pharmacodynamics, medicine, education, Rofecoxib, medicine.drug
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8
المؤلفون: M. Sturkenboom, Jeanne P. Dieleman, Meindert Danhof, O Della Pasqua, C. van Noord, Albert Hofman, Anne S. Y. Chain, Bruno H. Stricker
المصدر: Clinical Therapeutics. 35(8)
مصطلحات موضوعية: Clinical trial, Pharmacology, Nursing, Work (electrical), business.industry, Medicine, Pharmacology (medical), business
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9Not-in-trial simulation I: Bridging cardiovascular risk from clinical trials to real-life conditions
المؤلفون: Anne S Y, Chain, Jeanne P, Dieleman, Charlotte, van Noord, Albert, Hofman, Bruno H Ch, Stricker, Meindert, Danhof, Miriam C J M, Sturkenboom, Oscar, Della Pasqua
المصدر: British journal of clinical pharmacology. 76(6)
مصطلحات موضوعية: Adult, Male, Adolescent, Adrenergic beta-Antagonists, Sotalol, Middle Aged, Models, Biological, Risk Assessment, Healthy Volunteers, Statistics, Nonparametric, Methods in Clinical Pharmacology, Cohort Studies, Electrocardiography, Long QT Syndrome, Young Adult, Surveys and Questionnaires, Humans, Computer Simulation, Female, Prospective Studies
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10Assessing the probability of drug-induced QTc-interval prolongation during clinical drug development
المؤلفون: Meindert Danhof, Anne S. Y. Chain, O Della Pasqua, K M Krudys
المصدر: Clinical pharmacology and therapeutics. 90(6)
مصطلحات موضوعية: Drug, Adult, Male, medicine.medical_specialty, Adolescent, Drug-Related Side Effects and Adverse Reactions, media_common.quotation_subject, Bayesian probability, Guidelines as Topic, Pharmacology, QT interval, Models, Biological, Bayes' theorem, Young Adult, Heart Rate, Internal medicine, medicine, Humans, Pharmacology (medical), media_common, Clinical Trials as Topic, business.industry, Prolongation, Bayes Theorem, Middle Aged, Circadian Rhythm, Long QT Syndrome, Drug development, Pharmacodynamics, Drug Design, Dromotropic, Cardiology, Drug and Narcotic Control, Female, business