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المؤلفون: Yongsong Tian, Mohamed A. Shehata, Stine Juul Gauger, Carolina Veronesi, Louise Hamborg, Louise Thiesen, Jesper Bruus-Jensen, Johanne Schlieper Royssen, Ulrike Leurs, Anne Sofie G. Larsen, Jacob Krall, Sara M.Ø. Solbak, Petrine Wellendorph, Bente Frølund
المصدر: Journal of medicinal chemistry. 65(22)
مصطلحات موضوعية: Mice, Benzocycloheptenes, Binding Sites, Drug Discovery, Molecular Medicine, Animals, Brain, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Protein Binding
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المؤلفون: Geeske M. van Woerden, Christian D. Kelstrup, Emma K. Gowing, Inge S. Villumsen, Anders B. Klein, Birgitte Rahbek Kornum, Christine L. Gee, Nane Griem-Krey, Mohamed A. Shehata, Ulrike Leurs, Rasmus P. Clausen, Stine J. Gauger, Andrew N. Clarkson, Louise Hamborg, Anne Sofie G. Larsen, Chris C. Chi, Robert O. Burnie, Anders Bach, D. Steven Kerr, Jesper V. Olsen, Sara Marie Øie Solbak, Petrine Wellendorph, John Kuriyan, Ethan D McSpadden, Josh Houlton, Stine B. Vogensen, Selina M. W. Teurlings, Bente Frølund, Line B. Palmelund
المساهمون: Neurosciences
المصدر: Leurs, U, Klein, A B, McSpadden, E D, Griem-Krey, N, Solbak, S M O, Houlton, J, Villumsen, I S, Vogensen, S B, Hamborg, L, Gauger, S J, Palmelund, L B, Larsen, A S G, Shehata, M A, Kelstrup, C D, Olsen, J V, Bach, A, Burnie, R O, Kerr, D S, Gowing, E K, Teurlings, S M W, Chi, C C, Gee, C L, Frølund, B, Kornum, B R, van Woerden, G M, Clausen, R P, Kuriyan, J, Clarkson, A N & Wellendorph, P 2021, ' GHB analogs confer neuroprotection through specific interaction with the CaMKII alpha hub domain ', Proceedings of the National Academy of Sciences of the United States of America, vol. 118, no. 31 . https://doi.org/10.1073/pnas.2108079118
Proceedings of the National Academy of Sciences of the United States of America, 118(31):e2108079118. National Academy of Sciences
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, vol 118, iss 31مصطلحات موضوعية: Enzymologic, 0301 basic medicine, Carboxylic Acids, Excitotoxicity, Crystallography, X-Ray, medicine.disease_cause, 0302 clinical medicine, Neuropharmacology, G alpha subunit, Crystallography, Multidisciplinary, Chemistry, Biological Sciences, Small molecule, Neuroprotection, Stroke, 5.1 Pharmaceuticals, Development of treatments and therapeutic interventions, Sodium Oxybate, excitotoxicity, photoaffinity labeling, Protein Binding, Signal Transduction, photothrombotic stroke, photothrombotic storke, Cyclopentanes, Gene Expression Regulation, Enzymologic, 03 medical and health sciences, Protein Domains, Ca2+/calmodulin-dependent protein kinase, medicine, Humans, Binding site, x-ray crystallography, Pharmacology, Binding Sites, Photoaffinity labeling, Neurosciences, Brain Disorders, HEK293 Cells, 030104 developmental biology, Gene Expression Regulation, HOCPCA, X-Ray, Calcium-Calmodulin-Dependent Protein Kinase Type 2, Neuroscience, 030217 neurology & neurosurgery
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3968f82757f44ca335598be37cbc1e0
https://curis.ku.dk/portal/da/publications/ghb-analogs-confer-neuroprotection-through-specific-interaction-with-the-camkii-alpha-hub-domain(df178a50-331d-40f4-ae3d-8333cff82958).html
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