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1دورية أكاديمية
المؤلفون: Amy R. Rappaport, Sue-Jean Hong, Ciaran D. Scallan, Leonid Gitlin, Arvin Akoopie, Gregory R. Boucher, Milana Egorova, J. Aaron Espinosa, Mario Fidanza, Melissa A. Kachura, Annie Shen, Gloria Sivko, Anne Van Abbema, Robert L. Veres, Karin Jooss
المصدر: Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
مصطلحات موضوعية: Science
وصف الملف: electronic resource
Relation: https://doaj.org/toc/2041-1723
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2
المؤلفون: Amy R. Rappaport, Sue-Jean Hong, Ciaran D. Scallan, Leonid Gitlin, Arvin Akoopie, Gregory R. Boucher, Milana Egorova, J. Aaron Espinosa, Mario Fidanza, Melissa A. Kachura, Annie Shen, Gloria Sivko, Anne Van Abbema, Robert L. Veres, Karin Jooss
المصدر: Nature communications. 13(1)
مصطلحات موضوعية: Multidisciplinary, COVID-19 Vaccines, SARS-CoV-2, Vaccination, General Physics and Astronomy, COVID-19, General Chemistry, Antibodies, Viral, Antibodies, Neutralizing, Macaca mulatta, General Biochemistry, Genetics and Molecular Biology, Mice, Spike Glycoprotein, Coronavirus, Animals, Humans, RNA, Messenger
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3
المؤلفون: Leo Berezhkovsky, Mark Ultsch, Jan Smith, Wade S. Blair, Adam R. Johnson, Calum Macleod, Simon Charles Goodacre, Jason DeVoss, Jun Liang, Kapil Menghrajani, Jim Driscoll, Nico Ghilardi, Wenqian Yang, Steven Magnuson, Karen Williams, Anne van Abbema, Donnie Delarosa, Pawan Bir Kohli, Hieu Nguyen, Kathy Barrett, Steven Shia, Birong Zhang, Sue Sohn, Zhonghua Lin, Christine Chang, Mercedesz Balazs, Priscilla Mantik, Yingjie Lai, Charles Eigenbrot, Vickie Tsui, Amy Sambrone, Ivan Peng, Lawren C. Wu
المصدر: Bioorganicmedicinal chemistry letters. 27(18)
مصطلحات موضوعية: 0301 basic medicine, Imidazopyridine, Pyridines, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, In vivo, Psoriasis, Drug Discovery, medicine, Peptide bond, Humans, Molecular Biology, Protein Kinase Inhibitors, chemistry.chemical_classification, TYK2 Kinase, Dose-Response Relationship, Drug, Molecular Structure, Kinase, Aryl, Organic Chemistry, Imidazoles, medicine.disease, 030104 developmental biology, Enzyme, chemistry, Molecular Medicine, Selectivity, 030215 immunology
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المؤلفون: Yan Lou, Sharadha Subramanian, Yingyun Wang, Lifeng Wan, John Tellew, Laura Tandeske, Benjamin R. Taft, Kalyani Gampa, Jacob R. Haling, Gisele Nishiguchi, Lina Setti, Alice Rico, Sylvia Ma, Payman Amiri, Mallika Singh, Huw Tanner, Brent A. Appleton, Robert J. Aversa, Sepideh Vaziri, Shenlin Huang, Johanna M. Jansen, Anne Van Abbema, Jing Yuan, Vesselina G. Cooke, Hanne Merritt, Aaron Smith, Wenlin Shao, Valery Polyakov, Fei Feng, Savithri Ramurthy, Matthew Burger, Mulugeta Mamo, Lesley A. Mathews Griner, Vijay Sethuraman, Victoriano Tamez, Michael Patrick Dillon, Emma Lees, Ina Dix, Paul A. Barsanti, Richard Zang, Darrin Stuart, Mohammad Hekmat-Nejad
المصدر: Journal of medicinal chemistry. 60(12)
مصطلحات موضوعية: 0301 basic medicine, Proto-Oncogene Proteins B-raf, Mutant, Antineoplastic Agents, medicine.disease_cause, Crystallography, X-Ray, Proto-Oncogene Proteins p21(ras), 03 medical and health sciences, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, 0302 clinical medicine, 2,2'-Dipyridyl, Dogs, Drug Stability, Neoplasms, Drug Discovery, medicine, Structure–activity relationship, Animals, Humans, c-Raf, Molecular Targeted Therapy, Benzamide, Chemistry, Kinase, Drug discovery, Small molecule, Xenograft Model Antitumor Assays, Rats, 030104 developmental biology, Biochemistry, 030220 oncology & carcinogenesis, Drug Design, Benzamides, ras Proteins, Molecular Medicine, raf Kinases, KRAS
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5
المؤلفون: Wade S. Blair, Sue Sohn, Stanley Mark S, Pawan Bir Kohli, Leo Berezhkovskiy, Lawren C. Wu, James P. Driscoll, Charles Eigenbrot, Adam R. Johnson, Vickie Tsui, Birong Zhang, Paul Gibbons, Nico Ghilardi, Yingjie Lai, Jun Liang, Marya Liimatta, Amy Sambrone, Jeremy Murray, Young G. Shin, Jason Halladay, Yisong Xiao, Kathy Barrett, Christine Chang, Maureen Beresini, Steven Shia, Mark Ultsch, Bao Liang, Kapil Menghrajani, Jan Smith, Priscilla Mantik, Anne van Abbema, Steven Magnuson
المصدر: European Journal of Medicinal Chemistry. 67:175-187
مصطلحات موضوعية: Models, Molecular, TYK2 Kinase, Pharmacology, Dose-Response Relationship, Drug, Molecular Structure, Organic Chemistry, Inflammatory Bowel Diseases, General Medicine, Hit to lead, Combinatorial chemistry, Structure-Activity Relationship, chemistry.chemical_compound, chemistry, Biochemistry, Tyrosine kinase 2, Drug Discovery, Humans, HATU, Structure–activity relationship, Identification (biology), Protein Kinase Inhibitors, ADME
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6
المؤلفون: Sue Sohn, Nico Ghilardi, Priscilla Mantik, Christine Chang, Mercedesz Balazs, Paul Gibbons, Jan Smith, Ivan Peng, Jason DeVoss, Bing-Yan Zhu, Kathy Barrett, Wade S. Blair, Yisong Xiao, Steven Shia, Birong Zhang, Jim Driscoll, Donnie Delarosa, Young G. Shin, Jeremy Murray, Steven Magnuson, Leo Berezhkovsky, Wenqian Yang, Anne van Abbema, Charles Eigenbrot, Lawren C. Wu, Adam R. Johnson, Pawan Bir Kohli, Vickie Tsui, Mark Ultsch, Jason Halladay, Amy Sambrone, Yingjie Lai, Joseph P. Lyssikatos, Yanzhou Liu, Kapil Menghrajani, Jun Liang, Judy Young
المصدر: Journal of Medicinal Chemistry. 56:4521-4536
مصطلحات موضوعية: Models, Molecular, Administration, Oral, Aminopyridines, Biological Availability, Pharmacology, Crystallography, X-Ray, Interferon-gamma, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, Animals, Structure–activity relationship, Potency, 4-Aminopyridine, Benzamide, Cell potency, TYK2 Kinase, chemistry.chemical_classification, Gene knockdown, Chemistry, Janus Kinase 3, Stereoisomerism, Janus Kinase 1, Janus Kinase 2, STAT4 Transcription Factor, Interleukin-12, Rats, Enzyme, Biochemistry, Tyrosine kinase 2, Benzamides, Microsomes, Liver, Molecular Medicine, Protein Binding
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7
المؤلفون: Janusz J. Kulagowski, Claire Morris, Leslie Lee, Kathy Barrett, Sean P. Flynn, Richard Pastor, Michael Siu, Charles Eigenbrot, Deepak Sampath, Christine Chang, Jane R. Kenny, Aihe Zhou, Jeremy Murray, Joseph P. Lyssikatos, Christopher A. Hurley, Emily J. Hanan, Jeffrey M. Blaney, Wade S. Blair, Tom Rawson, Paul Gibbons, Steven Magnuson, Mark Ultsch, Anne van Abbema
المصدر: Journal of Medicinal Chemistry. 55:10090-10107
مصطلحات موضوعية: Models, Molecular, Pyrimidine, Somatic cell, Mice, SCID, Pharmacology, Pyrazolopyrimidine, Mice, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, hemic and lymphatic diseases, Drug Discovery, STAT5 Transcription Factor, Animals, Humans, Structure–activity relationship, Tissue Distribution, Phosphorylation, Protein Kinase Inhibitors, Janus kinase 2, Molecular Structure, biology, Kinase, food and beverages, Janus Kinase 2, Pyrimidines, chemistry, biology.protein, Molecular Medicine, Female, hormones, hormone substitutes, and hormone antagonists
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8
المؤلفون: Amy Rachel Rappaport, Kieu Lam, Renee Greer, Hadley Hanson, Petra Schreiner, Leonid Gitlin, Karin Jooss, Ciaran Daniel Scallan, Wade S. Blair, James Heyes, Anne van Abbema, Gijsbert Grotenbreg
المصدر: Cancer Research. 78:724-724
مصطلحات موضوعية: Cancer Research, medicine.medical_treatment, Heterologous, Biology, Virology, Viral vector, Vaccination, Immune system, Oncology, Cancer immunotherapy, Antigen, medicine, Expression cassette, Cancer vaccine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::934a606187e0f38a9fe33d7f56531baf
https://doi.org/10.1158/1538-7445.am2018-724 -
9
المؤلفون: Weihua Song, Daniel E. H. Afar, Peter Burger, Yu-Tzu Tai, Hervé Avet-Loiseau, Wanling Xie, Paul G. Richardson, Claire Mathiot, Audie G. Rice, Anne van Abbema, Xian Feng Li, Kenneth C. Anderson, Lynne Jesaitis, Edie Weller, Ingrid Caras, Alfred Ian Lee, Klaus Podar, Teru Hideshima, Nikhil C. Munshi, Myles B.C. Dillon, Merav Leiba, Debbie A. Law
المصدر: Blood. 112:1329-1337
مصطلحات موضوعية: Stromal cell, medicine.drug_class, Immunology, Biology, Monoclonal antibody, Biochemistry, Mice, Antigen, Antigens, Neoplasm, Bone Marrow, Signaling Lymphocytic Activation Molecule Family, Cell Adhesion, Tumor Cells, Cultured, medicine, Animals, Humans, RNA, Messenger, Receptors, Immunologic, Cell adhesion, Antibody-dependent cell-mediated cytotoxicity, Neoplasia, Bortezomib, SLAMF7, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, Cell Biology, Hematology, Xenograft Model Antitumor Assays, Molecular biology, medicine.anatomical_structure, Bone marrow, Stromal Cells, Multiple Myeloma, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f1999048162480a9413aa270f7095b
https://doi.org/10.1182/blood-2007-08-107292 -
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المؤلفون: Shankar Kumar, Gao Liu, Anne van Abbema, Susan Rhodes, Vladimir Vexler, Amulya Nanisetti, Benny P. Shum, John D. Shaughnessy, Melanie Wong, Naoya Tsurushita, Fenghuang Zhan, Shihao Chen, Daniel E. H. Afar, Aparna Draksharapu, Audie Rice, Mahrukh Huseni, David M. W. Powers, Bart Barlogie, Yin Zhang, Balaji Balasa, Marna Williams, Franklin Fuh, Mohamad A. Hussein, Eric D. Hsi, Roxanne Steinle, Susann Szmania, Myles B.C. Dillon, Frits van Rhee
المصدر: Clinical Cancer Research. 14:2775-2784
مصطلحات موضوعية: Cancer Research, Plasma Cells, CD34, Mice, SCID, Biology, Article, Mice, Signaling Lymphocytic Activation Molecule Family, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, medicine, Animals, Humans, Receptors, Immunologic, Elotuzumab, Multiple myeloma, Gene Expression Profiling, SLAMF7, Antibody-Dependent Cell Cytotoxicity, Antibodies, Monoclonal, medicine.disease, Xenograft Model Antitumor Assays, Molecular biology, Lymphocyte Subsets, Killer Cells, Natural, Haematopoiesis, medicine.anatomical_structure, Oncology, Female, Bone marrow, Stem cell, Multiple Myeloma, CD8, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a51201b042fb124cd1c452c079014fcf
https://doi.org/10.1158/1078-0432.ccr-07-4246
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