المؤلفون: Ruth Luthi-Carter, Barbara L Apostol, Anthone W Dunah, Molly M DeJohn, Laurie A Farrell, Gillian P Bates, Anne B Young, David G Standaert, Leslie M Thompson, Jang-Ho J Cha

المصدر: Neurobiology of Disease, Vol 14, Iss 3, Pp 624-636 (2003)

مصطلحات موضوعية: Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: http://www.sciencedirect.com/science/article/pii/S0969996103001724; https://doaj.org/toc/1095-953X

URL الوصول: https://doaj.org/article/4e6b60ce52e44b97b00d9332a0e9f1f1

المؤلفون: Darren P. Baker, Laura Silvian, Edward Lin, Chris Bergeron, Robert M. Arduini, Craig P. Wildes, Catherine Hession, Kevin Guckian, Jean-Christophe Hus, Anthone W. Dunah, Charles C. Banos, Douglas Marcotte

المصدر: Protein Science. 27:672-680

مصطلحات موضوعية: 0301 basic medicine, Chemistry, media_common.quotation_subject, Protein subunit, PDZ domain, AMPA receptor, Endocytosis, Biochemistry, Cell biology, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, medicine, Neuron, Internalization, Receptor, PICK1, Molecular Biology, 030217 neurology & neurosurgery, media_common

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::212ac2b24f808f8365e37735c02e02cb
https://doi.org/10.1002/pro.3361

المؤلفون: Flora Jow, Istvan J. Enyedy, Darren P. Baker, Catherine Hession, Chris Bergeron, Kenneth J. Rhodes, Robert H. Scannevin, Cassandra F. Borenstein, Gnanasambandam Kumaravel, Edward Yin-Shiang Lin, Timothy R. Chan, Anthone W. Dunah, Richard L. Huganir, Laura Silvian, Jinming Zou, Robert M. Arduini, Fang Qian, Ellen Rohde, Kevin Guckian, Marion Wittmann, Douglas Marcotte, Charles C. Banos

المصدر: Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)

مصطلحات موضوعية: 0301 basic medicine, Dendritic spine, Amyloid beta, Dendritic Spines, PDZ domain, lcsh:Medicine, PDZ Domains, Cell Cycle Proteins, AMPA receptor, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Animals, Calcium Signaling, Receptors, AMPA, Long-term depression, lcsh:Science, Calcium signaling, Multidisciplinary, Amyloid beta-Peptides, biology, Chemistry, lcsh:R, Brain, Nuclear Proteins, Neurodegenerative Diseases, Cell biology, 030104 developmental biology, Drug Design, Synaptic plasticity, Synapses, biology.protein, lcsh:Q, Calcium, PICK1, Carrier Proteins, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809e124eb19a18665035c8a00f6cabaf
http://europepmc.org/articles/PMC6128908

المؤلفون: Anthone W. Dunah, Thierry Bussiere, Kenneth J. Rhodes, Hairuo Peng, Lin Xu, Mahin Arastu, Gnanasambandam Kumaravel, Joy Wang, Melanie S. Brennan, Pamela A. Snodgrass-Belt, Arthur G. Taveras, Mi-young Jung, Tina Talreja, Sowmya Chollate, Zhili Xin, Diana Fahrer, Robert Dunstan, Robert H. Scannevin, Ellen Rohde, H. Moore Arnold

المصدر: Neuropharmacology. 103:57-68

مصطلحات موضوعية: Male, 0301 basic medicine, Gene isoform, Pathology, medicine.medical_specialty, Central nervous system, BACE1-AS, Plaque, Amyloid, Cleavage (embryo), Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, 0302 clinical medicine, Alzheimer Disease, Amyloid precursor protein, medicine, Animals, Protein Isoforms, Pharmacology, Aldehydes, Amyloid beta-Peptides, Dose-Response Relationship, Drug, biology, P3 peptide, Brain, medicine.disease, Rats, Inbred F344, Rats, Disease Models, Animal, Macaca fascicularis, 030104 developmental biology, medicine.anatomical_structure, biology.protein, Amyloid Precursor Protein Secretases, Alzheimer's disease, Amyloid precursor protein secretase, 030217 neurology & neurosurgery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e3c58874b2fa09f0f97a25626acfb40
https://doi.org/10.1016/j.neuropharm.2015.12.006

المؤلفون: Douglas J, Marcotte, Jean-Christophe, Hus, Charles C, Banos, Craig, Wildes, Robert, Arduini, Chris, Bergeron, Catherine A, Hession, Darren P, Baker, Edward, Lin, Kevin M, Guckian, Anthone W, Dunah, Laura F, Silvian

المصدر: Protein Science : A Publication of the Protein Society

مصطلحات موضوعية: Models, Molecular, proteolysis, Binding Sites, Crystallography, Molecular Conformation, Nuclear Proteins, PDZ Domains, PDZ domain small molecule inhibitors, Articles, class II PDZ binding motif, Article, Small Molecule Libraries, Structure-Activity Relationship, PDZ domain inhibitor cocrystallization, Drug Design, PICK1 PDZ domain crystal structure, Humans, Receptors, AMPA, Carrier Proteins, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8bedd5ddc5302836513b41b7e2443266
https://pubmed.ncbi.nlm.nih.gov/29280296

المؤلفون: Shuko Takeda, Susanne Wegmann, Benjamin D. Moore, Anthone W. Dunah, Rose Pitstick, Chloe K. Nobuhara, Caitlin Commins, Allyson D. Roe, Bradley T. Hyman, Paul H. Weinreb, George A. Carlson, Thierry Bussiere, Sarah L. DeVos, Christoph Hock, Anne Cheung, Jan Grimm, Fabio Montrasio, Marion Wittmann, Matthew P. Frosch, Roger M. Nitsch, Isabel Costantino

المساهمون: University of Zurich, Hyman, Bradley T

مصطلحات موضوعية: 0301 basic medicine, Male, Interneuron, Transgene, 610 Medicine & health, Mice, Transgenic, tau Proteins, Epitope, Pathology and Forensic Medicine, 03 medical and health sciences, Epitopes, 0302 clinical medicine, Alzheimer Disease, Interneurons, mental disorders, medicine, Extracellular, Animals, Humans, Molecular Targeted Therapy, Cognitive decline, Phosphorylation, Cells, Cultured, Aged, 80 and over, Neurons, Chemistry, Antibodies, Monoclonal, Brain, Regular Article, Neurofibrillary Tangles, 11359 Institute for Regenerative Medicine (IREM), Microfluidic Analytical Techniques, medicine.disease, In vitro, Cell biology, 2734 Pathology and Forensic Medicine, 030104 developmental biology, medicine.anatomical_structure, Female, Alzheimer's disease, 030217 neurology & neurosurgery

وصف الملف: Nobuhara_J_Pathology_2017.pdf - application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1219d1f2726721caa936d6e629fe50
https://europepmc.org/articles/PMC5455060/

المؤلفون: Roberto Malinow, Anthone W. Dunah, Charles C. Banos, Richard L. Huganir, Kenneth J. Rhodes, Timothy R. Chan, Helmut W. Kessels, Gnanasambandam Kumaravel, Stephanie Alfonso, Edward Lin, Kevin Guckian, Robert H. Scannevin

المساهمون: Netherlands Institute for Neuroscience (NIN)

المصدر: The European journal of neuroscience, 39(7), 1225-33. Wiley-Blackwell

مصطلحات موضوعية: Amyloid beta, Protein subunit, PDZ domain, Cell Cycle Proteins, Neurotransmission, Hippocampus, Article, Synapse, Mice, 03 medical and health sciences, 0302 clinical medicine, Animals, Receptors, AMPA, Receptor, Cells, Cultured, 030304 developmental biology, Neurons, 0303 health sciences, Amyloid beta-Peptides, biology, General Neuroscience, P3 peptide, Excitatory Postsynaptic Potentials, Nuclear Proteins, Peptide Fragments, Rats, 3. Good health, Synapses, biology.protein, Carrier Proteins, PICK1, Neuroscience, 030217 neurology & neurosurgery, Protein Binding

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822fd5e041b6d490a3407fc7e3a8bf26
https://hdl.handle.net/20.500.11755/afccf325-bbf2-4f33-a1c8-16e0e0416470

المؤلفون: Victor Hong, Andres McKenzie, Jianhua Chao, Erin K Harning, Ping Li, Francis Burrows, Jiandong Shi, Rachel Lough, Theodore J. Yun, Marcus F. Boehm, Gerardo Ibanez, Ryan Lamer, Kenneth W Weichert, Christina Boykin, Anthone W. Dunah, Istvan J. Enyedy, Christine Ambrose, Noelito Timple, Ryan Van de Water, Marilyn R. Kehry, Marco A. Biamonte, Joseph Arndt, Jeffrey Thompson, Srinivas Rao Kasibhatla, Cristina M Sandoval, Karen Lundgren, Kevin Hong, Pamela A. Snodgrass-Belt, Sarah A. Bixler

المصدر: Journal of Medicinal Chemistry. 55:7786-7795

مصطلحات موضوعية: chemistry.chemical_classification, biology, Chemistry, Ligand binding assay, Phases of clinical research, Alkyne, Hsp90, Molecular biology, In vitro, Pyrimidines, X-Ray Diffraction, In vivo, Heat shock protein, Drug Discovery, biology.protein, Humans, Molecular Medicine, Pyrroles, Gastric tumor, HSP90 Heat-Shock Proteins

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11fc27a2a6949bbbf83404c803f06d5a
https://doi.org/10.1021/jm300810x

المؤلفون: Robert H. Scannevin, Tina Talreja, Lin Xu, Gnanasambandam Kumaravel, David Kocisko, Arthur G. Taveras, Anthone W. Dunah, Hairuo Peng, Kenneth J. Rhodes, Ellen Rohde, H. Moore Arnold, Sowmya Chollate, Pamela A. Snodgrass-Belt, Mi-yong Jung, Andrew Zhang, Zhili Xin, Melanie N. Shackett

المصدر: Bioorganic & Medicinal Chemistry Letters. 21:7277-7280

مصطلحات موضوعية: Scaffold, Carboxylic acid, Clinical Biochemistry, Drug Evaluation, Preclinical, Administration, Oral, Pharmaceutical Science, Pharmacology, Biochemistry, Mice, chemistry.chemical_compound, Piperidines, Oral administration, Drug Discovery, Animals, γ secretase, Enzyme Inhibitors, Molecular Biology, Phenylacetates, chemistry.chemical_classification, Amyloid beta-Peptides, Nonsteroidal, Anti-Inflammatory Agents, Non-Steroidal, Organic Chemistry, Brain, Combinatorial chemistry, Peptide Fragments, Rats, chemistry, Drug Design, Molecular Medicine, Amyloid Precursor Protein Secretases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fff16ea306e260e39cfe769d34265e32
https://doi.org/10.1016/j.bmcl.2011.10.047

المؤلفون: Tina Talreja, Arthur G. Taveras, Michael Humora, Lawrence Gan, J. Hernan Cuervo, Kenneth J. Rhodes, Hairuo Peng, Lin Xu, Anthone W. Dunah, Gnanasambandam Kumaravel, Pamela A. Snodgrass-Belt, Mi-young Jung, Zhili Xin, Sowmya Chollate, Melanie N. Shackett, Ellen Rohde, H. Moore Arnold, Robert H. Scannevin

المصدر: ACS Medicinal Chemistry Letters. 2:786-791

مصطلحات موضوعية: biology, business.industry, Organic Chemistry, Notch signaling pathway, Pharmacology, Biochemistry, In vitro, Pharmacokinetics, In vivo, Oral administration, Pharmacodynamics, Drug Discovery, biology.protein, Medicine, Potency, business, Amyloid precursor protein secretase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f8cd4a82fc2be0e7dceb3dc620003c
https://doi.org/10.1021/ml200175q